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Sarcoma Genomics – Felix Haglund de Flon's Group

The Sarcoma Genomics research group is focused on biomarker discovery and investigating the tumor biology of sarcoma. We strive to advance precision medicine and improve outcomes for sarcoma patients.

Part of the:

Our research

Our research focuses on sarcoma genomics, integrating clinical, translational, and preclinical studies to improve diagnostics and treatment strategies. We aim to identify novel biomarkers, tumor subtypes, and therapeutic targets through whole-genome and transcriptome sequencing (WGTS) and methylation profiling.

Selected collaborations

  • Basel University Hospital, Switzerland
  • Lund University, Sweden
  • Harvard University, USA
  • Memorial Sloan Kettering Cancer Center, USA
  • Scandinavian Sarcoma Group

Publications

Selected publications

  • Article: CANCERS. 2024;16(22):3816
    Ofverholm I; Lin Y; Mondini J; Hardingz J; Braenstroem R; Tsagkozis P; Wirta V; Gellerbring A; Lindberg J; Chellappa V; Mayrhofer M; Haglund C; Haglund de Flon F; Wallander K
  • Article: ADVANCED SCIENCE. 2024;11(41):e2404510
    Chen Y; Su Y; Cao X; Siavelis I; Leo IR; Zeng J; Tsagkozis P; Hesla AC; Papakonstantinou A; Liu X; Huang W-K; Zhao B; Haglund C; Ehnman M; Johansson H; Lin Y; Lehtioe J; Zhang Y; Larsson O; Li X; de Flon FH
  • Article: CLINICAL CANCER RESEARCH. 2024;30(12):2647-2658
    Ofverholm I; Wallander K; Haglund C; Chellappa V; Wejde J; Gellerbring A; Wirta V; Renevey A; Caceres E; Tsagkozis P; Mayrhofer M; Papakonstantinou A; Linder-Stragliotto C; Branstrom R; Larsson O; Lindberg J; Lin Y; de Flon FH
  • Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(6):690-707
    Wallander K; Ofverholm I; Boye K; Tsagkozis P; Papakonstantinou A; Lin Y; de Flon FH
  • Article: BRITISH JOURNAL OF SURGERY. 2023;110(12):1857-1862
    Berndsen M; Renberg S; Holmebakk T; Hancke E; Puls F; Karlsson F; Stoldt S; Bjerkehagen B; de Flon FH; Muth A; Papakonstantinou A; Boye K; Lindskog S
  • Article: GENES CHROMOSOMES & CANCER. 2023;62(10):607-610
    Haglund C; Zemmler M; Tsagkozis P; Haglund de Flon F
  • Article: INTERNATIONAL JOURNAL OF CANCER. 2022;151(6):906-913
    Renberg S; Zhang Y; Karlsson F; Branstrom R; Ahlen J; Jalmsell L; Linder-Stragliotto C; Haglund de Flon F; Papakonstantinou A
  • Article: CANCER MEDICINE. 2022;11(14):2729-2734
    Zhang Y; Renberg S; Papakonstantinou A; de Flon FH
  • Article: BIOMOLECULES. 2022;12(2):292
    Zhang Y; Chen Y; Papakonstantinou A; Tsagkozis P; Linder-Stragliotto C; Haglund F
  • Article: MODERN PATHOLOGY. 2021;34(11):2020-2027
    Zhang Y; Chen Y; Yang C; Seger N; Hesla AC; Tsagkozis P; Larsson O; Lin Y; Haglund F
  • Article: ONCOLOGY REPORTS. 2021;46(2):168
    Yang C; Zhang Y; Segar N; Huang C; Zeng P; Tan X; Mao L; Chen Z; Haglund F; Larsson O; Chen Z; Lin Y
  • Article: CANCERS. 2021;13(15):3736
    Chen Y; Su H; Su Y; Zhang Y; Lin Y; Haglund F
  • Article: DIAGNOSTIC CYTOPATHOLOGY. 2021;49(1):46-53
    Zhang Y; Alagic Z; Tani E; Skorpil M; Tsagkozis P; Haglund F
  • Article: MOLECULAR ONCOLOGY. 2020;14(5):1101-1117
    Chen Y; Hesla AC; Lin Y; Ghaderi M; Liu M; Yang C; Zhang Y; Tsagkozis P; Larsson O; Haglund F
  • Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2020;1296:319-348
    Tsagozis P; Gonzalez-Molina J; Georgoudaki A-M; Lehti K; Carlson J; Lundqvist A; Haglund F; Ehnman M
  • Article: PLOS ONE. 2020;15(7):e0236291
    Yang C; Zhang Y; Chen Y; Ragaller F; Liu M; Corvigno S; Dahlstrand H; Carlson J; Chen Z; Nasman A; Waraky A; Lin Y; Larsson O; Haglund F
  • Article: CYTOPATHOLOGY. 2019;30(5):504-509
    Zhang Y; Wessman S; Wejde J; Tani E; Haglund F
  • Preprint: SSRN ELECTRONIC JOURNAL. 2019
    Chen Y; Hesla AC; Lin Y; Ghaderi M; Liu M; Yang C; Zhang Y; Tsagkozis P; Larsson O; Haglund F
  • Article: MODERN PATHOLOGY. 2018;31(12):1834-1841
    Lin Y; Seger N; Chen Y; Hesla AC; Wejde J; Ghaderi M; Tsagkozis P; Larsson O; Haglund F
  • Article: JOURNAL OF CLINICAL PATHOLOGY. 2018;71(9):832-839
    Lin Y; Seger N; Tsagkozis P; Hesla AC; Ghaderi M; Chen Y; Ehnman M; Warsito D; Wejde J; Larsson O; Haglund F
  • Show more

Funding

  • Cancerfonden
  • The Cancer Society in Stockholm
  • The Swedish Childhood Cancer Foundation
  • The Swedish Society of Medicine
  • The Swedish Sarcoma Society

Staff and contact

Group leader

All members of the group

Dissertations

Yi Chen
Genetic and molecular mechanisms of sarcomas 
4 March 2022

Yifan Zhang 
Morphologic and genetic features of sarcomas: improving diagnosis and exploring biomarkers
23 September 2023

Ahmed Waraky
Insulin-like growth factor 1 receptor, novel functions and future possibilities
22 September 2017

 

Keywords:
Biomarkers Cancer and Oncology Cell and Molecular Biology Genomics Medical Genetics and Genomics Show all
Content reviewer:
Felix Haglund de Flon
Erika Rindsjö
21-03-2025