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Skin diseases – Lennart Emtestam group

Since the 1980's, the group has worked with non-invasive measuring techniques for aid in the diagnosis of the skin. The methods are based on the principle that pathological tissue has different physical properties compared to normal skin.

The group is part of the Infectious Diseases and Dermatology Unit at the Department of Medicine, Huddinge (MedH).

Projects

1. Skin cancer diagnostic tool using electrical impedance spectroscopy

This project includes work with a non-invasive tool based on electrical impedance for distinguishing various pathological tissue from normal skin. The project is under commercialization. For more information about the project, visit 

Main collaborator:

  • , CLINTEC, ̽»¨¾«Ñ¡.

Funding:

  • Edvard Welander Foundation
  • Finsen foundation
  • Cancer and Allergy Foundation
  • Stockholm City Council
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2. Skin cancer diagnostic tool based on micromachined interface for high-resolution THz spectroscopy (MTSSC)

This project focuses on developing a micromachined interface for microwave/THz characterization of skin tissue, mainly for distinguishing skin anomalies from healthy tissue and for distinguishing malignant and benign skin tumors.

Collaborators:

  • KTH-EE-MST-RF MEMS (Joachim Oberhammer)
  • Uppsala University (UU) - Signals and Systems (Anders Rydberg)
  • Optiga AB (Lars Tenerz)

Funding:

  • Vinnova
  • Edvard Welander Foundation
  • Finsen Foundation

3. Hidradenitis suppurativa

Hidradenitis suppurativa is a cicatrizing and frequently persistent inflammatory disorder of the sebaceous follicles and terminal hair follicles of apocrine gland-bearing areas in the adult. This project started in the 1980s and focuses on investigating different aspects of the disease, including treatment, etiology and epidemiology. Two important contributions to the scientific community from the group: First, a minimal-invasive carbon dioxide laser treatment was developed by Jan Lapins. Second, the internationally established "Sartorius Score" a disease severity assessment tool was proposed by Karin Sartorius.

Collaborators:

  • Copenhagen University (Gregor Jemec)
  • University Hospital of Northern Norway (Gisli Ingvarsson)

Funding:

  • Edvard Welander Foundation
  • Finsen foundation
  • Cancer and Allergy Foundation
  • Stockholm City Council
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Publications

Selected publications

  • Editorial comment: BRITISH JOURNAL OF DERMATOLOGY. 2021;184(5):796-798
    Emtestam L; Lapins J; Sartorius K
  • Article: ARCHIVES OF DERMATOLOGICAL RESEARCH. 2020;312(10):715-724
    Riis PT; Saunte DM; Sigsgaard V; Villani AP; Guillem P; Pascual JC; Kappe NN; Vanlaerhoven AMJD; van der Zee HH; Prens EP; El-Domyati M; Abdel-Wahab H; Moftah N; Abdelghani R; Agut-Busquet E; Romani J; Hlela C; van den Worm L; Bettoli V; Calamo G; Gurer MA; Beksac B; Matusiak L; Glowaczewska A; Szepietowski JC; Emtestam L; Lapins J; Kottb HR; Fatani M; Weibel L; Theiler M; Delage-Toriel M; Thi THL; Nassif A; Becherel P-A; Dolenc-Voljc M; Doss N; Bouazzi D; Benhadou F; del Marmol V; Jemec GBE
  • Article: DERMATOLOGY. 2020;236(4):281-288
    Killasli H; Sartorius K; Emtestam L; Svensson A
  • Editorial comment: BRITISH JOURNAL OF DERMATOLOGY. 2018;178(3):591-592
    Emtestam L; Sartorius K
  • Article: BRITISH JOURNAL OF DERMATOLOGY. 2018;178(3):715-721
    Thorlacius L; Garg A; Ingram JR; Villumsen B; Riis PT; Gottlieb AB; Merola JF; Dellavalle R; Ardon C; Baba R; Bechara FG; Cohen AD; Daham N; Davis M; Emtestam L; Fernandez-Penas P; Filippelli M; Gibbons A; Grant T; Guilbault S; Gulliver S; Harris C; Harvent C; Houston K; Kirby JS; Matusiak L; Mehdizadeh A; Mojica T; Okun M; Orgill D; Pallack L; Parks-Miller A; Prens EP; Randell S; Rogers C; Rosen CF; Choon SE; van der Zee HH; Christensen R; Jemec GBE
  • Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2018;32(2):307-312
    Riis PT; Saunte DM; Benhadou F; del Marmol V; Guillem P; El-Domyati M; Abdel-Wahab H; Antoniou C; Dessinioti C; Gurer MA; Beksac B; Szepietowski JC; Matusiak L; Emtestam L; Lapins J; Riad H; Doss N; Massa AF; Hamzavi I; Nicholson C; Dolenc-Voljc M; Kim KH; Ohn J; Zouboulis CC; Karagiannidis I; Mokos ZB; Durinec P; Jemec GBE
  • Editorial comment: BRITISH JOURNAL OF DERMATOLOGY. 2017;177(3):625-627
    Emtestam L; Sartorius K
  • Letter: DERMATOLOGIC SURGERY. 2017;43(4):604-605
    Emtestam L; Lapins J; Sartorius K
  • Article: JOURNAL OF AMERICAN ACADEMY OF DERMATOLOGY. 2016;75(6):1151-1155
    Riis PT; Boer J; Prens EP; Saunte DML; Deckers IE; Emtestam L; Sartorius K; Jemec GBE