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Epidemiology of sarcoidosis and systemic lupus erythematosus – Team Elizabeth Arkema

Our overarching goal is to better understand the causes and consequences of sarcoidosis and lupus. Our mission is to provide evidence-based answers to etiological and clinical questions using epidemiological methods.

Our goal and mission

Our overarching goal is to better understand the causes and consequences of sarcoidosis and lupus. Specifically, our aims are to:

  • Identify risk factors for sarcoidosis and lupus
  • Reduce the time from symptoms to diagnosis
  • Improve treatment strategies for sarcoidosis and lupus
  • Minimize the long-term consequences of sarcoidosis and lupus

Our mission is to provide evidence-based answers to etiological and clinical questions using epidemiological methods.

About our research

We use contemporary Swedish population-based register data to better understand the demographic, clinical and lifestyle factors which drive increased risks of outcomes related to chronic inflammatory diseases, in particular, lupus and sarcoidosis. Our work focuses on quantifying risks so that care for people with lupus and sarcoidoisis can be improved.

Sweden’s high quality and comprehensive healthcare data allow us to conduct large-scale investigations of risk factors for and outcomes after sarcoidosis and lupus. These nationwide data from health and demographic registers form the basis of our data repository for research. It is further enriched by the inclusion of clinical and laboratory data from hospital-based registers.

Publications

Selected publications

  • Article: RHEUMATOLOGY. 2025;:keaf004
    Patasova K; Dehara M; Mantel A; Bixo M; Arkema EV; Holmqvist M
  • Article: RHEUMATOLOGY. 2025;64(1):117-125
    Nguyen NV; Svenungsson E; Dominicus A; Altman M; Hellgren K; Simard JF; Arkema EV
  • Article: BMJ OPEN. 2024;14(12):e090555
    Gernaat SAM; Simard JF; Altman M; Svenungsson E; Arkema EV
  • Article: JOURNAL OF AUTOIMMUNITY. 2024;149:103127
    Arkema EV; Rossides M; Cozier YC
  • Article: EUROPEAN RESPIRATORY JOURNAL. 2024;64(6):2400277
    Arkema EV; Sachs MC; Dominicus A; Eklund A; Smed-Sorensen A; Grunewald J; Blomberg A
  • Article: CHEST. 2024;166(5):1082-1092
    Rossides M; Kullberg S; Arkema EV
  • Article: LUPUS. 2024;33(11):1192-1202
    Mageau A; Simard JF; Svenungsson E; Arkema EV
  • Article: SCIENTIFIC REPORTS. 2024;14(1):19260
    Ziehfreund S; Tizek L; Arkema EV; Zink A
  • Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2024;39(3):313-322
    Dehara M; Kullberg S; Bixo M; Sachs MC; Grunewald J; Arkema EV
  • Review: JOURNAL OF INTERNAL MEDICINE. 2023;293(6):668-680
    Rossides M; Darlington P; Kullberg S; Arkema EV

Funding

Grants

  • Swedish Research Council
  • Swedish Heart-Lung Foundation
  • Swedish Cancer Society
  • Swedish Research Council

Our work is supported by grants from, among others:

  • Swedish Research Council
  • Swedish Heart-Lung Foundation
  • National Institutes of Health
  • Swedish Society for Medicine
  • Strategic Research Area in Epidemiology (SFO Epi)
  • Ingegerd Johansson Foundation
  • ̽»¨¾«Ñ¡ Research Foundation

Staff and contact

Group leader

All members of the group


Statistician

Collaboration

Our work brings together the expertise of clinicians, immunologists and epidemiologists. Collaborations are essential for the exchange of expertise from all scientific fields and we welcome researchers interested in chronic inflammatory disease research to contact us.

Keywords:
Autoimmunity and Inflammation Epidemiology Public Health, Global Health and Social Medicine Rheumatology Sarcoidosis
Content reviewer:
12-06-2024