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Hyperbaric oxygen therapy (HBOT) is a clinical method used for 14 different diagnoses where oxygen is given at 240-280 kPa (compared to breathing room air ~21kPa or breathing pure oxygen ~100kPa). The chamber is located at the Karolinska University Hospital in Solna.
 

Research projects

Hyperbaric Oxygen for Treatment of Long COVID syndrome; A Randomized, Placebo-Controlled, Double-Blind, Phase II Clinical Trial

Principal Investigator Anders Kjellberg
Contact Person: Anders Kjellberg
Coordinating Investigator: Peter Lindholm

Financial support: Swedish Research Council, The Swedish Heart Lung Foundation and Avtal om Läkarutbildning och Forskning (ALF).

A Randomized, Controlled, Open Label, Multicentre Clinical Trial to explore Safety and Efficacy of Hyperbaric Oxygen for preventing ICU admission, Morbidity and Mortality in Adult Patients With COVID-19

Coordinating investigator Anders Kjellberg

Sponsor representative Peter Lindholm

Contact: Anders Kjellberg

Read more about the clinical trial 

Selected publications

Kjellberg A, Douglas J, Pawlik M T, Kraus M, Oscarsson N, Zheng X et al
BMJ Open, protocol

Kjellberg A, De Maio A, Lindholm P 
Med Hypotheses 2020 Nov;144():110224

Biomarkers in HBOT

PhD-project for Anders Kjellberg.
Main supervisor P. Lindholm.

Supervisors K.Rodriguez-Wallberge S.Catrina, X.Zheng and E.Weitzberg

Biomarkers for oxidative stress and HIF1 upregulation during Hyperbaric Oxygen and Ischemia Reperfusion Injury- a Translational project on Hyperbaric oxygen for Preconditioning.

Rich-Art study group

Local PI KI Anders Kjellberg. PI Niclas Oscarsson.

Selected publications

Oscarsson N, Müller B, Rosén A, Lodding P, Mölne J, Giglio D, et al
Lancet Oncol. 2019 Nov;20(11):1602-1614

Imaging and the lung in diving medicine

Selected publications

Lindholm P, Swenson ER, Martínez-Jiménez S, Guo HH
Am. J. Respir. Crit. Care Med. 2018 10;198(8):1088-1089

Schiffer TA, Lindholm P
Eur. J. Appl. Physiol. 2013 Mar;113(3):803-10

Lindholm P, Norris CM, Braver JM, Jacobson F, Ferrigno M
Respir Physiol Neurobiol 2009 Jun;167(2):189-94

Lindholm P, Ekborn A, Oberg D, Gennser M
J. Appl. Physiol. 2008 Apr;104(4):912-7

Lindholm P, Nyrén S
Eur. J. Appl. Physiol. 2005 Aug;94(5-6):646-51

Hypoxia and hyperoxia

Selected publications

Manselin TA, Södergård O, Larsen FJ, Lindholm P
Physiol Rep 2017 Jan;5(2):

Lindholm P, Lundgren CE
Undersea Hyperb Med ;33(6):463-7

Lindholm P, Gennser M
Eur. J. Appl. Physiol. 2005 Mar;93(5-6):701-7

Lindholm P, Sundblad P, Linnarsson D
J. Appl. Physiol. 1999 Dec;87(6):2122-7

Magnetic resonance imaging in pulmonary embolism (Dr Lindholms radiology research)

PhD-student: Deepa Gopalan

MD, PhD: Koshiar Medson

Selected publications

Gopalan D, Nordgren-Rogberg A, Le EPV, Pavey H, Tarkin J, Nyrén S, et al
J Am Heart Assoc 2020 Nov;9(21):e018075

Nyrén S, Nordgren Rogberg A, Vargas Paris R, Bengtsson B, Westerlund E, Lindholm P
Acta Radiol 2017 Mar;58(3):272-278

Rogberg AN, Gopalan D, Westerlund E, Lindholm P
Acta Radiol 2019 Nov;60(11):1576-1583

Medson K, Vargas-Paris R, Nordgren-Rogberg A, Sigbergsdottir A, Nyrén S, Lindholm P
Eur J Radiol Open 2019 ;6():315-319

Support our research

Collaborations

• Kenny Rodriguez-Wallberg, Professor, Department of Oncology-Pathology, ̽»¨¾«Ñ¡.
• Nicklas Oscarsson, MD, Sahlgrenska Academy, Gothemburg.
• Sergiu-Bogdan Catrina, Lecturer/senior physician, Research group leader of the group Growth and Metabolism, Department of Molecular Medicine and Surgery, Karolinska Insitutet.
• Bo-Michael Bellander, Lecturer senior, adjunct, Department of Clinical Neuroscience, ̽»¨¾«Ñ¡.
• Xiao-Wei Zheng, Senior lab manager, Department of Molecular Medicine and Surgery, Ì½»¨¾«Ñ¡.
• Agneta Larsson, Affiliated to research, Department of Physiology and Pharmacology, Ì½»¨¾«Ñ¡.
• Eddie Weitzberg, Professor/senior physician of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Ì½»¨¾«Ñ¡.
• Michael Nekludov, MD, PhD, postdoc, Department of Oncology-Pathology, ̽»¨¾«Ñ¡.
• Malin Nygren-Bonnier, Associate Professor and Senior Lecturer,  Division of Physiotherapy, Department of NVS, ̽»¨¾«Ñ¡ and the Medical Unit of Occupational Therapy and Physiotherapy at the Karolinska University Hospital.
• Judith Bruchfeld, Affiliated to research, Department of Medicine at ̽»¨¾«Ñ¡.
• Marcus StÃ¥hlberg, Affiliated to research, Department of Medicine at ̽»¨¾«Ñ¡.
• Mikael Runold, Överläkare Karolinska Universitetssjukhuset
• Anna Norrby-Teglund, MD, PhD, Professor, Center for Infectious Medicine, ̽»¨¾«Ñ¡, and Karolinska University Hospital.
• Folke Lind, M.D., Ph.D., FUHM, Assistant Professor (retired), Karolinska Insitutet, Physician Emeritus, Karolinska University hospital, Senior Consultant Hyperbaric Medicine
• John Pernow, Professor i kardiologi vid institutionen för medicin, ̽»¨¾«Ñ¡
• Carl-Johan Sundberg, Professor i molekylär och tillämpad arbetsfysiologi vid institutionen för fysiologi och farmakologi, samt prefekt vid institutionen för lärande, informatik, management och etik (LIME), ̽»¨¾«Ñ¡