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Molly Stevens group

Our goal is to study the fundamental science of cell-material interactions and apply this knowledge to the design of biomaterials that translate into clinical solutions.

Our research

The ability to regenerate damaged tissue is one of the great challenges in the fields of tissue engineering and regenerative medicine. Our goal is to study the fundamental science of cell-material interactions and apply this knowledge to the design of biomaterials that translate into clinical solutions. Our group is developing approaches to control cell behaviour through their innate ability to sense and respond to local meso-, micro-, and nanoscale patterns of chemistry, stiffness, and topography. Our polymer systems can be functionalised for drug delivery and with biological and synthetic cues to instruct the entire lifecycle of the tissue, from cell binding and differentiation, to cell-induced material remodeling and ultimate tissue organisation and function. These materials though designed for the clinic can be also used as platform systems to study a wide variety of instructive environments for tissue regeneration and cell fate. The Stevens group is also innovating how the cell-material interface can be explored with cutting edge materials analysis approaches such as live cell micro-Raman spectroscopy and correlative nanoscale resolution imaging approaches.

Collaboration

We are working in close collaboration with our sister group at Imperial College London, UK .

The Stevens group has been awarded over 20 major awards including the 2014 Research group of the year at the European Life Sciences Awards and the EU40 Prize from the European Materials Research Society for best materials scientist under 40.

Publications

Selected publications

  • Article: NATURE MATERIALS. 2015;14(5):532-539
    Chiappini C; De Rosa E; Martinez JO; Liu X; Steele J; Stevens MM; Tasciotti E
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(14):4280-4285
    Autefage H; Gentleman E; Littmann E; Hedegaard MAB; Von Erlach T; O'Donnell M; Burden FR; Winkler DA; Stevens MM
  • Article: ADVANCED HEALTHCARE MATERIALS. 2014;3(9):1381-1386
    Chow LW; Armgarth A; St-Pierre J-P; Bertazzo S; Gentilini C; Aurisicchio C; McCullen SD; Steele JAM; Stevens MM
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(16):5908-5913
    Horejs C-M; Serio A; Purvis A; Gormley AJ; Bertazzo S; Poliniewicz A; Wang AJ; DiMaggio P; Hohenester E; Stevens MM
  • Review: TISSUE ENGINEERING PART B-REVIEWS. 2014;20(1):1-16
    Harrison RH; St-Pierre J-P; Stevens MM
  • Article: NATURE MATERIALS. 2013;12(6):576-583
    Bertazzo S; Gentleman E; Cloyd KL; Chester AH; Yacoub MH; Stevens MM
  • Article: NATURE NANOTECHNOLOGY. 2012;7(12):821-824
    de la Rica R; Stevens MM
  • Review: SCIENCE TRANSLATIONAL MEDICINE. 2012;4(160):160sr4
    Pashuck ET; Stevens MM
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(35):14170-14175
    Boonrungsiman S; Gentleman E; Carzaniga R; Evans ND; McComb DW; Porter AE; Stevens MM
  • Article: NATURE MATERIALS. 2012;11(7):604-607
    Rodriguez-Lorenzo L; de la Rica R; Alvarez-Puebla RA; Liz-Marzan LM; Stevens MM
  • Article: NATURE CHEMISTRY. 2011;3(8):582-589
    Mager MD; LaPointe V; Stevens MM
  • Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2011;133(5):1438-1450
    Hung A; Mwenifumbo S; Mager M; Kuna JJ; Stellacci F; Yarovsky I; Stevens MM
  • Article: BIOMATERIALS. 2010;31(14):3949-3956
    Gentleman E; Fredholm YC; Jell G; Lotfibakhshaiesh N; O'Donnell MD; Hill RG; Stevens MM
  • Article: NATURE MATERIALS. 2009;8(9):763-770
    Gentleman E; Swain RJ; Evans ND; Boonrungsiman S; Jell G; Ball MD; Shean TAV; Oyen ML; Porter A; Stevens MM
  • Review: NATURE MATERIALS. 2009;8(6):457-470
    Place ES; Evans ND; Stevens MM
  • Review: SCIENCE. 2005;310(5751):1135-1138
    Stevens MM; George JH
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(32):11450-11455
    Stevens MM; Marini RP; Schaefer D; Aronson J; Langer R; Shastri VP

Staff and contact

Group leader

All members of the group

Keywords:
Biomaterials Science Medical Biotechnology (Focus on Cell Biology (incl. Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Content reviewer:
29-04-2024