Our research
In the group, we focus our research on the following aspects:
- Epidemiology, molecular biology and certain immunological mechanisms of hematological malignancie.;
- The biological role of lipoxygenases, a family of enzymes which catalyzes the formation of active lipid mediators. The studies focus on the expression of lipoxygenases as a diagnostic tool and biological function in lymphoma.
- Cellular/molecular aspects of carcinogenesis and aging. Here we emphasize the role of telomerase and telomere in cancer development and aging process. Telomerase is an enzyme elongating telomere at chromosome ends, and both telomerase and telomere are important players in cancer and aging.
Our study projects above have both biological and clinical implications, and the obtained results will contribute to precision medicine.
Ongoing research
- Telomerase activation and association with the ETS family transcription factor GABPA in cancer.
- The direct and indirect role of telomerase reverse transcriptase (TERT) in inhibition of virus infection.