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Malignant melanoma – Hildur Helgadottir's Group

Our research is focused on malignant melanoma. We study melanoma incidence, biology, genetics and different aspects related to prevention and treatment of the disease.

Hildur Helgadottir's research group.
Hildur Helgadottir's research group

Our projects

1. Epidemiological studies in which health and population registers are used to map factors linked to melanoma.

2. Preventive studies to identify high-risk individuals, such as those with genetic predisposition, and to identify unknown genetic factors associated with melanoma.

3. We are studying melanoma in younger individuals to better understand factors that are related to early onset and treatment of melanoma in young patients ().

4. A phase II study in which we investigate whether the effect of immunotherapy can be improved by adding precision radiation to the metastases ().

5. Studies to identify molecular factors that may predict treatment effect in patients with metastatic melanoma (BioMelanoma).

6. Clinically relevant issues regarding genetic predisposition, treatment prediction and the emergence of treatment resistance in metastatic melanoma are also elucidated through studies on tumor models in in vitro and in vivo studies.

Networks

  • -The Melanoma Genetics Consortiom
  • -Melanoma in Children, Adolescents, and Young Adults
  • SMSG -Swedish Melanoma Study Group
  • SweFAM -Swedish Network on Familial Melanoma

 

Publications

Selected publications

  • Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2025
    Girmay Y; Portelli F; Mikiver R; Lapins J; Isaksson K; Helgadottir H
  • Article: JAMA DERMATOLOGY. 2024;160(11):1201-1210
    Helgadottir H; Mikiver R; Schultz K; Nielsen K; Portelli F; Lapins J; Puig S; Isaksson K
  • Article: IMMUNO-ONCOLOGY AND TECHNOLOGY. 2024;22:100713
    Costa Svedman F; Liapi M; MÃ¥nsson-Broberg A; Chatzidionysiou K; Egyhazi Brage S
  • Article: EUROPEAN JOURNAL OF CANCER. 2024;202:114010
    Helgadottir H; Matikas A; Fernebro J; Frodin J-E; Ekman S; Rodriguez-Wallberg KA
  • Article: ACTA ONCOLOGICA. 2023;62(12):1921-1930
    Backlund E; Grozman V; Brage SE; Lewensohn R; Lindberg K; Helgadottir H
  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2023;115(9):1077-1084
    Helgadottir H; Ny L; Ullenhag GJ; Falkenius J; Mikiver R; Bagge RO; Isaksson K
  • Letter: ACTA ONCOLOGICA. 2023;62(6):565-570
    Helgadottir H; Schultz K; Lapins J; Vassilaki I; All-Eriksson C; Hoiom V
  • Letter: ACTA ONCOLOGICA. 2022;61(9):1116-1120
    Costa Svedman F; Jalsenius M; Grozman V; Bergqvist M; Soderdahl F; Rotstein S; Ny L; Egyhazi Brage S; Helgadottir H
  • Article: CANCERS. 2022;14(15):3587
    Svedman FC; Das I; Tuominen R; Ramqvist ED; Hoiom V; Brage SE
  • Letter: ACTA ONCOLOGICA. 2022;61(7):869-873
    Backlund E; Yang M; Grozman V; Masucci G; Falkenius J; Eriksson H; Jovanovic B; Hammarlund K; Isacsson U; Radu C; Abel E; Karlsson K; Palanco Zamora R; Wersall P; Edback U; Wickstrom S; Darai Ramqvist E; Egyhazi Brage S; Kiessling R; Viktorsson K; Franzen B; Lewensohn R; Olofsson Bagge R; Ullenhag GJ; Ny L; Lindberg K; Helgadottir H
  • Editorial comment: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(3 PT A):736-740.e6
    Das I; Tuominen R; Helleday T; Hansson J; Berglund UW; Brage SE
  • Article: GENETICS IN MEDICINE. 2022;24(1):157-169
    Yang M; Johnsson P; Brautigam L; Yang XR; Thrane K; Gao J; Tobin NP; Zhou Y; Yu R; Nagy N; Engstrom PG; Tuominen R; Eriksson H; Lundeberg J; Tucker MA; Goldstein AM; Egyhazi-Brage S; Zhao J; Cao Y; Hoiom V
  • Article: CANCER RESEARCH. 2021;81(9):2545-2555
    Karlsson MJ; Svedman FC; Tebani A; Kotol D; Hoiom V; Fagerberg L; Edfors F; Uhlen M; Brage SE; Maddalo G
  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2021;113(3):318-328
    Helgadottir H; Isaksson K; Fritz I; Ingvar C; Lapins J; Hoiom V; Newton-Bishop J; Olsson H
  • Article: JOURNAL OF MEDICAL GENETICS. 2020;57(5):316-321
    Helgadottir H; Ghiorzo P; van Doorn R; Puig S; Levin M; Kefford R; Lauss M; Queirolo P; Pastorino L; Kapiteijn E; Potrony M; Carrera C; Olsson H; Hoiom V; Jonsson G
  • Article: CELL DEATH & DISEASE. 2019;10(9):663
    Das I; Wilhelm M; Hoiom V; Marquez RF; Svedman FC; Hansson J; Tuominen R; Brage SE
  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2016;108(11):djw135
    Helgadottir H; Hoiom V; Tuominen R; Nielsen K; Jonsson G; Olsson H; Hansson J

Funding

  • The Swedish Cancer Society
  • The Cancer Research Funds of Radiumhemmet
  • ³§Âáö²ú±ð°ù²µ²õ³Ù¾±´Ú³Ù±ð±ô²õ±ð²Ô
  • Region Stockholm grants (ALF)
  • ̽»¨¾«Ñ¡'s research funds
  • SciLifeLab Post-doc grant
  • European Union Funding -Horizon Europe

Staff and contact

Group leader

All members of the group

Fernanda Costa Svedman

Affiliated to research
Keywords:
Cancer and Oncology Cell and Molecular Biology Medical Genetics and Genomics
Content reviewer:
06-03-2025