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Real-world-data in multiple sclerosis – Anna Glaser's research group

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system affecting more than two million people world-wide. MS is the second most common cause of neurological disability in young adults. The disease progression varies between patients but often causes different degrees of disability.

About our research

In the research group we use data from the Swedish MS register sometimes also linked to data from Swedish public databases such as the National Board of Health and Welfare (Socialstyrelsen), Statistics Sweden (SCB) and the Swedish Social Insurance Agency (Försäkringskassan). 

Using this type of “real-world data”, we want to describe disease progression, treatment methods and socio-economic outcomes in MS patients. Our hope is that our studies will contribute to increased knowledge about factors that affect MS disease with the ambition to ultimately create improved and cost-effective health care for MS patients.

The research group includes molecular biologists, statisticians and neurologists.

Research Projects

  • MS clinical course
    Description and analysis of MS disease progression. Studies of different factors influencing disease progression.
     
  • Treatment studies
    Safety and efficacy studies.
     
  • Health economic consequences of MS
    Costs of MS, sick leave, disability pension, income.
     

Publications

Selected publications

  • Letter: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2024;88:105726
    He A; Manouchehrinia A; Glaser A; Butzkueven H; Ciccarelli O; Hillert J; McKay KA
  • Article: JOURNAL OF NEUROLOGY. 2024;271(6):3616-3624
    Glaser A; Butzkueven H; van der Walt A; Gray O; Spelman T; Zhu C; Trojano M; Iaffaldano P; Battaglia MA; Lucisano G; Vukusic S; Vukusic I; Casey R; Horakova D; Drahota J; Magyari M; Joensen H; Pontieri L; Elberling F; Klyve P; Mouresan EF; Forsberg L; Hillert J
  • Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2023;94(4):284-289
    He A; Spelman T; Manouchehrinia A; Ciccarelli O; Hillert J; McKay K
  • Article: MULTIPLE SCLEROSIS JOURNAL - EXPERIMENTAL, TRANSLATIONAL AND CLINICAL. 2023;9(1):20552173231153557
    Forsberg L; Spelman T; Klyve P; Manouchehrinia A; Ramanujam R; Mouresan E; Drahota J; Horakova D; Joensen H; Pontieri L; Magyari M; Ellenberger D; Stahmann A; Rodgers J; Witts J; Middleton R; Nicholas R; Bezlyak V; Adlard N; Hach T; Lines C; Vukusic S; Soilu-Hanninen M; van der Walt A; Butzkueven H; Iaffaldano P; Trojano M; Glaser A; Hillert J
  • Article: THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. 2023;16:17562864231198963
    Nicholas R; Rodgers J; Witts J; Lerede A; Friede T; Hillert J; Forsberg L; Glaser A; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Pontieri L; Magyari M; Ellenberger D; Stahmann A; Butzkueven H; Van der Walt A; Bezlyak V; Lines C; Middleton R
  • Article: FRONTIERS IN NEUROLOGY. 2023;14:1274194
    Spelman T; Magyari M; Butzkueven H; van der Walt A; Vukusic S; Trojano M; Iaffaldano P; Horakova D; Drahota J; Pellegrini F; Hyde R; Duquette P; Lechner-Scott J; Sajedi SA; Lalive P; Shaygannejad V; Ozakbas S; Eichau S; Alroughani R; Terzi M; Girard M; Kalincik T; Grand'Maison F; Skibina O; Khoury SJ; Yamout B; Sa MJ; Gerlach O; Blanco Y; Karabudak R; Oreja-Guevara C; Altintas A; Hughes S; Mccombe P; Ampapa R; de Gans K; Mcguigan C; Soysal A; Prevost J; John N; Inshasi J; Stawiarz L; Manouchehrinia A; Forsberg L; Sellebjerg F; Glaser A; Pontieri L; Joensen H; Rasmussen PV; Sejbaek T; Poulsen MB; Christensen JR; Kant M; Stilund M; Mathiesen H; Hillert J
  • Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2023;69:104456
    Teni FS; Machado A; Murley C; He A; Fink K; Gyllensten H; Glaser A; Alexanderson K; Hillert J; Friberg E
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2022;28(7):1051-1059
    Spelman T; Forsberg L; McKay K; Glaser A; Hillert J
  • Article: ANNALS OF NEUROLOGY. 2022;91(3):417-423
    McKay KA; Bedri SK; Manouchehrinia A; Stawiarz L; Olsson T; Hillert J; Fink K
  • Article: JAMA NEUROLOGY. 2021;78(10):1197-1204
    Spelman T; Magyari M; Piehl F; Svenningsson A; Rasmussen PV; Kant M; Sellebjerg F; Joensen H; Hillert J; Lycke J
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(12):1875-1883
    Manouchehrinia A; Kingwell E; Zhu F; Tremlett H; Hillert J; Ramanujam R
  • Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2021;92(10):1096-1102
    Hedstrom AK; Hillert J; Olsson T; Alfredsson L
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(10):1543-1555
    Iaffaldano P; Lucisano G; Butzkueven H; Hillert J; Hyde R; Koch-Henriksen N; Magyari M; Pellegrini F; Spelman T; Sorensen PS; Vukusic S; Trojano M
  • Article: SCIENTIFIC REPORTS. 2021;11(1):14987
    Karrenbauer VD; Bedri SK; Hillert J; Manouchehrinia A
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(8):1240-1249
    Ramanujam R; Zhu F; Fink K; Karrenbauer VD; Lorscheider J; Benkert P; Kingwell E; Tremlett H; Hillert J; Manouchehrinia A
  • Article: JAMA NEUROLOGY. 2021;78(4):478-482
    McKay KA; Friberg E; Razaz N; Alexanderson K; Hillert J
  • Article: FRONTIERS IN NEUROLOGY. 2021;12:647811
    Hillert J; Magyari M; Soelberg Sorensen P; Butzkueven H; Van Der Welt A; Vukusic S; Trojano M; Iaffaldano P; Pellegrini F; Hyde R; Stawiarz L; Manouchehrinia A; Spelman T
  • Editorial comment: NATURE REVIEWS NEUROLOGY. 2020;16(4):191-192
    Hillert J
  • Article: LANCET NEUROLOGY. 2020;19(4):307-316
    He A; Merkel B; Brown JWL; Ryerson LZ; Kister I; Malpas CB; Sharmin S; Horakova D; Havrdova EK; Spelman T; Izquierdo G; Eichau S; Trojano M; Lugaresi A; Hupperts R; Sola P; Ferraro D; Lycke J; Grand'Maison F; Prat A; Girard M; Duquette P; Larochelle C; Svenningsson A; Petersen T; Grammond P; Granella F; Van Pesch V; Bergamaschi R; McGuigan C; Coles A; Hillert J; Piehl F; Butzkueven H; Kalincik T
  • Article: NEUROLOGY. 2020;94(9):e932-e941
    McKay KA; Ernstsson O; Manouchehrinia A; Olsson T; Hillert J
  • Article: FRONTIERS IN IMMUNOLOGY. 2020;11:583560
    Dunn N; Fogdell-Hahn A; Hillert J; Spelman T
  • Article: NEUROLOGY. 2019;92(24):e2764-e2773
    Mckay KA; Hillert J; Manouchehrinia A
  • Article: JAMA NEUROLOGY. 2019;76(6):665-671
    Beiki O; Frumento P; Bottai M; Manouchehrinia A; Hillert J
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2017;23(14):1938-1946
    Manouchehrinia A; Westerlind H; Kingwell E; Zhu F; Carruthers R; Ramanujam R; Ban M; Glaser A; Sawcer S; Tremlett H; Hillert J
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2017;23(9):1233-1240
    Kavaliunas A; Manouchehrinia A; Stawiarz L; Ramanujam R; Agholme J; Hedstrom AK; Beiki O; Glaser A; Hillert J
  • Article: JAMA NEUROLOGY. 2015;72(10):1117-1123
    Ramanujam R; Hedstrom A-K; Manouchehrinia A; Alfredsson L; Olsson T; Bottai M; Hillert J
  • Review: ACTA NEUROLOGICA SCANDINAVICA. 2015;132(199):11-19
    Hillert J; Stawiarz L
  • Show more

Staff and contact

Group leader

All members of the group

Keywords:
Epidemiology Multiple Sclerosis Neurology Neurosciences Public Health, Global Health and Social Medicine
03-02-2025