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History

Cellular electron microscopy has been a key technique for understanding the cell’s core elements and mechanisms since the 1950s. Electron microscopic methods have laid the foundation for a number of Nobel Prizes and have given us much of the basic understanding of human cells’ overall structure, physiology and mechanisms—basically the foundation of all modern medicine.

In recent years, electron microscopy has undergone extremely rapid development through a combination of significantly better optics, sample processing, detectors and image processing. The development has given rise to the so-called “Resolution Revolution,” which in recent years has gradually increased the average resolution of biological preparations significantly. Part of the discoveries and methodology resulted in a Nobel Prize to Richard Henderson, Jaques Dubochet and Joachim Frank in 2017. At the beginning of this revolution, a visionary decision by ̽����ѡ’s (KI’s) leadership was made to build premises for a future electron microscopy center nearby the Biomedicum building at the KI Solna campus. These premises have now been built specifically for high-end bio̽����ѡ electron microscopy. During 2019-2020 the newly built KI 3D-EM core facility was equipped with the best possible equipment, enabling a much broader group of KI researchers to utilize the enormous advances in electron microscopy in recent years.