探花精选

Division of Virology and Immunology

The Division of Virology and Immunology at the Department of Microbiology, Tumor and Cell Biology (MTC) at 探花精选 comprises ten research groups working on different aspects of molecular virology, viral immunity, T- and B-cell biology, vaccine responses to complex antigens and tumor immunology. Our vision is to drive innovative studies that advance our understanding of viral diseases and cancers, and to develop treatments that will make significant contributions to global health.

Division of Virology and Immunology- Research Groups and teams

 

Regulation of Gene Expression during Viral Infection- Gerald McInerney Group

Our research concerns the study of the interactions between viruses and their host cells in the early stages of infection. Using Semliki Forest virus as a model, we are exploring the involvement of cellular pathways such as autophagy, stress granules and the type I interferon system in the cellular responses to viral infection.

Regulation of Gene Expression during Viral Infection 鈥 Gerald McInerney Group

 

Contact

Profile image

Gerald Mc Inerney

Division Head and Research Group Leader

 

Genetic basis for B and T cell recognition and function- Gunilla Karlsson Hedestam Group

Our research focuses on adaptive immune responses and qualitative properties of B- and T-cell repertoires. A specific interest in the group is to understand individual variation in germline V, D and J genes and how this influences antigen-specific responses in the context of infection, vaccination and autoimmunity.

Genetic basis for B and T cell recognition and function 鈥 Gunilla Karlsson Hedestam Group

 

Contact

 

Inflammatory responses in cancer and autoimmunity- Mikael Karlsson's Group

Autoinflammation is part of several types of diseases. It drives auto-reactive B cells that contribute to autoimmune disease and create an environment in which tumors are allowed to grow. Our group studies the innate mechanism that are connected to this with special focus on B cells and Macrophages.

Inflammatory responses in cancer and autoimmunity 鈥 Mikael Karlsson's Group

 

Contact

Profile image

Mikael Karlsson

Research Group Leader

 

Immunodeficiency Diseases- Lisa Westerberg Group

The overall goal of our research is to understand how a compromised immune system leads to immunodeficiency with high incidence of autoimmunity and hematological cancers. We have a particular focus on how inborn mutations in actin regulators affect immune cell-cell communication, trafficking, and maintenance of genomic stability. Our research aims at revealing critical mechanisms for correct regulation of the immune system in health and disease and to identifying new targets for therapy.

Immunodeficiency Diseases 鈥 Lisa Westerberg Group 

 

Contact

Profile image

Lisa Westerberg

Research Group Leader

 

 

Computational Virology and Immunology - Ben Murrell Research Group

We work across the computational/experimental divide, currently focusing on developing probabilistic models and inference algorithms for studying evolving systems (including viruses and the immune responses against them) and designing  interventions.

Computational Virology and Immunology - Ben Murrell Research Group

Contact

Profile image

Benjamin Murrell

Research Group Leader

 

Immunological memory of Innate Lymphoid Cells- Itziar Martinez Gonzalez Project

Our research interests are focused in the study of the biology of memory Group 2 Innate Lymphoid Cells (ILC2s) in type 2 immunity.

Itziar Martinez Gonzalez Project

 

Jonathan Coquet Group

Our group is interested in how T cells develop and differentiate in response to antigens and cytokines. In particular, the group is focused on understanding the role of T cells in allergy and cancer.

 

Jonathan Coquet Group

 

Profile image

Jonathan Coquet

Principal Researcher

 

Pia Dosenovic team

Studies B cells for the development of new vaccines.

Profile image

Pia Dosenovic

Principal Researcher

 

 

Sheward Lab

The development of effective vaccines against HIV and other highly variable viruses for which there are no licensed vaccines is a major global health priority. The ability to pre-emptively vaccinate against clades of viruses with pandemic potential could also prevent another global pandemic.

Sheward Lab

Daniel Sheward

Assistant Professor

Staff and contact

Head of Division

All members of the group