Understanding microbe-induced stomach cancer – the key to a workable strategy for worldwide prevention
Stomach cancer is the 4th most common cancer and 2nd leading cause of cancer-related deaths worldwide. Helicobacter pylori infection is the single most important risk factor for stomach cancer.
Although theoretically population-based widespread eradication of the bacterium can reduce stomach cancer incidence and mortality, the concerns of inducing multidrug resistance problems and iatrogenic diseases related to Helicobacter pylori eradication, have hampered the implementation of this approach. We aim to develop a cost-effective and safe program for stomach cancer prevention through identification of high-risk groups, on which chemoprevention or endoscopic screening can be targeted.
Prinicipal Investigator
Project Acronym
PreventStoCan (project number 682663)
Funder
ERC consolidator grant
Team Members
Weimin Ye
Principal Investigator, ProfessorAmir Sohrabi
Affiliated to ResearchJoar Franzén
Phd StudentYun Du
Affiliated to ResearchFormer team members
- Huan Song
- Justine Debelius
- Ulrika Zagai
- Nikolaos Tertipis
- Isabella Ekheden
Publications
Zhang T, Yang X, Yin X, Yuan Z, Chen H, Jin L, Chen X, Lu M, Ye W
J Periodontol 2022 07;93(7):988-1002
Yin X, Yang X, Zhang T, Yuan Z, Chen H, Jin L, Chen X, Lu M, Ye W
J Cancer 2021 ;12(10):3089-3097
Sohrabi A, Franzen J, Tertipis N, Zagai U, Li W, Zheng Z, Ye W
Diagnostics (Basel) 2021 Aug;11(9):
Man J, Ni Y, Yang X, Zhang T, Yuan Z, Chen H, Chen X, Lu M, Ye W
Front Nutr 2021 ;8():774530
Song H, Ekheden IG, Ploner A, Ericsson J, Nyren O, Ye W
Int J Epidemiol 2018 04;47(2):440-449