Lithium treatment in bipolar disorder - biomarkers and effects
Lithium is the first-line treatment for bipolar disorder, but not everyone is helped by lithium.
We are therefore conducting a prospective study to identify clinically useful molecular markers with the aim of early detection of whether a patient will benefit from lithium therapy or not. We also participate in international consortia studying genetic factors behind bipolar disorder and the effects of lithium therapy. Furthermore, we study somatic side effects of lithium treatment.
Team leaders: Lena Backlund, Martin Schalling
Lena Backlund
Affiliated to ResearchMartin Schalling
ProfessorKey co-investigator
Catharina Lavebratt
Principal ResearcherCo-workers in the Translational Psychiatry Group:
Vincent Millischer
Affiliated to ResearchMartin Lundberg
Phd StudentKatja Ponzer
DoktorandFredrik Wikström
Affiliated to Research;Phd StudentAndra nyckelpersoner vid KI
Selected Publications
Millischer V, Matheson GJ, Bergen SE, Coombes BJ, Ponzer K, Wikström F, Jagiello K, Lundberg M, Stenvinkel P, Biernacka JM, Breuer O, Martinsson L, Landén M, Backlund L, Lavebratt C, Schalling M
Lancet Psychiatry 2022 Jun;9(6):447-457
Lundberg M, Millischer V, Backlund L, Martinsson L, Stenvinkel P, Sellgren CM, Lavebratt C, Schalling M
Front Psychiatry 2020 ;11():586083
Veldic M, Millischer V, Port JD, Ho AM, Jia YF, Geske JR, Biernacka JM, Backlund L, McElroy SL, Bond DJ, Villaescusa JC, Skime M, Choi DS, Lavebratt C, Schalling M, Frye MA
Transl Psychiatry 2019 05;9(1):149
Lundberg M, Biernacka JM, Lavebratt C, Druliner B, Ryu E, Geske J, Colby C, Boardman L, Frye M, Schalling M
Psychiatry Res 2020 04;286():112865
Backlund L, Wei YB, Martinsson L, Melas PA, Liu JJ, Mu N, Östenson CG, Ekström TJ, Schalling M, Lavebratt C
Mol Neuropsychiatry 2015 Jul;1(2):76-81
Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C
Int J Neuropsychopharmacol 2015 Jan;18(7):pyv002
Lavebratt C, Olsson S, Backlund L, Frisén L, Sellgren C, Priebe L, Nikamo P, Träskman-Bendz L, Cichon S, Vawter MP, Osby U, Engberg G, Landén M, Erhardt S, Schalling M
Mol Psychiatry 2014 Mar;19(3):334-41
Martinsson L, Wei Y, Xu D, Melas PA, Mathé AA, Schalling M, Lavebratt C, Backlund L
Transl Psychiatry 2013 May;3():e261