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CANOPTIPHYS

CanOptiPhys - Optimizing Physical function before surgery: effects on complications and physical function after gastrointestinal Cancer surgey in older people at risk.

This project is an extension of the previous Better in Better out project, see publications below.

The study is a joint study between ̽»¨¾«Ñ¡, Karolinska University Hospital, South General Hospital, Ersta Hospital, Academic Primary Health Care Center and RISE Research Institute of Sweden.

Patients are recruited at the hospital when a decision about surgery has been set. The intervention in the RCT is performed in the older person’s home, led by physiotherapists working in primary care. The intervention consists of a combination of respiratory training and individually adjusted functional exercise, which has not been evaluated previously. If the study shows positive effects, it can be of great importance for older persons’ independence and quality of life as well as from a socioeconomic perspective. 

Recruitment of participants ended in June, 2023 and analyses are ongoing.

Principal Investigator

Profile image

Elisabeth Rydwik

Senior Lecturer/Physcial Therapist

Project members

Mikael Andersson, PhD

PhD, surgeon

Johanna Danielsson, PhD student

Julia Engström Sid, PhD student

Malin Nygren-Bonnier, docent

Christian Sturesson, docent, surgeon

Mattias Soop, PhD, surgeon

Anders Thorell, professor, surgeon

Publications


Andersson M, Egenvall M, Danielsson J, Thorell A, Sturesson C, Soop M, Nygren-Bonnier M, Rydwik E
Trials 2023 Jan;24(1):41

Publications from the previous Better in Better out project


Egenvall M, Karlsson E, Nygren-Bonnier M, Franzén E, Rydwik E
Clin Nutr ESPEN 2021 Dec;46():330-335


Karlsson E, Farahnak P, Franzén E, Nygren-Bonnier M, Dronkers J, van Meeteren N, Rydwik E
PLoS One 2019 ;14(7):e0219158


Karlsson E, Dahl O, Rydwik E, Nygren-Bonnier M, Bergenmar M
Support Care Cancer 2020 Aug;28(8):3945-3953


Karlsson E, Egenvall M, Farahnak P, Bergenmar M, Nygren-Bonnier M, Franzén E, Rydwik E
Eur J Surg Oncol 2018 11;44(11):1760-1767


Karlsson E, Franzén E, Nygren-Bonnier M, Bergenmar M, Rydwik E
J Geriatr Oncol 2019 07;10(4):610-617

Doctoral thesis

Emelie Karlsson 2019:

Content reviewer:
02-04-2025