探花精选

About the Karolinska ATMP Center

The Karolinska ATMP Center, a collaboration between 探花精选 and Karolinska University Hospital, is a leading ATMP Center in Europe with research, production and treatment under one roof. The center has high ambitions to strengthen and deepen collaboration with public actors and pharmaceutical companies.

Background

The major advances in research and development of advanced therapies in the ATMP field have the potential to treat and cure diseases in a way that has not been possible with traditional drugs and treatments. We are already seeing examples of gene therapy drastically improving the survival of patients suffering from certain types of cancer.

The collaboration between KI and Karolinska University Hospital on cell and gene therapies has a long tradition:

Already in 1975, the foundations were laid for today鈥檚 department of in Huddinge, which is the unit in Sweden that performs the most stem cell transplants and cell therapies. Today, children and adult patients with cancer and immune diseases are offered blood stem cell transplantation and several ATMP drugs within standard treatment and clinical trials. Karolinska's program is and includes not only CAST but also pediatric hematology and transfusion medicine (KITM). At CAST, Sweden's first standard treatment with CAR-T cells was performed in 2019.

The Vecura GMP unit at the in Huddinge, which today consists of 13 clean rooms, produced Sweden's first gene therapy drug for clinical trials in 1997 and the first CAR-T cells to enter clinical trials in Europe in 2014. Another GMP facility with a special focus on immunotherapy is located at the Karolinska Comprehensive Cancer Center (KCCC) in Solna.

In 2019, the first pre-GMP unit in the Nordic region was inaugurated at 探花精选 Campus Flemingsberg, with five clean rooms. The pre-GMP unit is an important bridge between research laboratories and Vecura and has been instrumental in the development of two therapeutic products currently undergoing clinical trials.

Mission statement

The Karolinska ATMP Center aims to consolidate all activities in advanced therapeutics at 探花精选 and Karolinska University Hospital to strengthen the development and implementation of cell, gene and tissue therapies.

Organisation

Knut Steffensen, Director, Karolinska ATMP Center

Ewa Ellis, coordinator Karolinska ATMP Center

Steering Committee

Olof Akre, R&D Director, Karolinska University Hospital.

Mathias Axelsson, Head of Medical Diagnostics Karolinska (MDK), Karolinska University Hospital.

Martin Berg枚, Vice President, 探花精选.

Jonas Fuxe, Head of the Department of Laboratory Medicine, 探花精选.

, Acting CEO, Karolinska University Hospital.

Matti S盲llberg, Dean KI South, 探花精选.

Christina Sundqvist, Coordinator Steering Committee, 探花精选.

Board of Directors

Knut Steffensen, Director, Karolinska ATMP Center.

R&D

Director: Samir EL Andaloussi, Professor, 探花精选.
Deputy Director: Rula Zain-Luqman, Docent, Karolinska University Hospital.

Production

Director: Pontus Blomberg, Docent, Karolinska University Hospital.
Deputy Director: Gustaf Ahl茅n, PhD, 探花精选.

Clinical Research and Implementation

Director: Stephan Mielke, Professor, 探花精选.
Deputy Director: Teng Wang, Docent, Karolinska University Hospital.

Content reviewer:
28-01-2025