探花精选

Vasco Sousa

Vasco Sousa

Senior Research Infrastructure Specialist
Telephone: +46852483254
Visiting address: BioClinicum J5:20, Akademiska str氓ket 1, Karolinska universitetssjukh, 17164 Solna
Postal address: K8 Klinisk neurovetenskap, K8 Imaging CF ARG, 171 77 Stockholm
Part of:

About me

  • I'm currently head of unit / manager of the autoradiography core facility. Our main mission is to help develop new pharmaceuticals and imaging tracers with clinical significance. Together with the other facilities in our division and the Center for Imaging Research (CIR), we form a hub for cutting-edge imaging research that is internationally recognized.
    I have worked at the 探花精选 since late 2010. I have over 7 years of experience as a senior lab manager and for 5 years as coordinator for the Strategic Research Area Neuroscience (StratNeuro). Between 2011 and 2014 I was a postdoctoral researcher.

    Education:
    2010 - PhD in Neuroscience from the Faculty of Medicine, University of Lisbon (PT).
    2005 - BSc Hon degree in Neuroscience from the University of Glasgow (UK).

Research

  • The autoradiography core facility (ARG CF) is a core facility at the Division of Imaging Core Facilities, Department of Clinical Neuroscience, Karolinska Institute. Our facility is fully outfitted and staffed to support radioligand binding and autoradiography studies. We provide full service and consultation, or training and access to equipment for our users to carry out their studies.
    The methods that our facility specializes in are important in pharmacology and cellular signaling research, as well as for development and validation of tracers for positron emission tomography (PET) imaging.
    Radioligand binding is used to study the binding properties of a radioactive isotope-labelled compound (radioligand) to a specific target, such as a receptor or enzyme.
    Autoradiography is used to visualize the location and distribution of a radioligand in a sample and assess its target-specificity.

Teaching

  • @ Department of Clinical Neuroscience, 探花精选 (Stockholm, SE),
    鈥 2011-present: course co-organizer, teaching and examiner in the doctoral course 鈥淣europsychopharmacology鈥 (course #2526).
    鈥 2017: Taught 鈥淏ehavioral tests for measuring depression鈥 in the doctoral course 鈥淢aking the most of Behavioral Methods in Rat and Mouse (course #CFK 2946).
    鈥 2011-2013: Taught 鈥減re-clinical models of major depressive disorder鈥 on the 鈥淔rontiers in Translational Medicine鈥 course within the KI MSc. program.
    鈥 Doctoral students advised
    . 2014: Tiberiu Loredan Stan (as co-supervisor)
    鈥 Master鈥檚 students advised
    . 2013-2014 co-supervised 3 students from University of Milan, through the Erasmus program, 6 month projects.

    @ Faculty of Medicine & Faculty of Science, University of Lisbon (Lisbon, PT)
    鈥 2008-2010: Taught 鈥渃annabinoid pharmacology鈥 on the Biochemistry Msc program (Faculty of Science) and the Neuroscience Msc program (Faculty of Medicine).
    鈥 2007-2010: Taught "measuring neurotransmitter release鈥 on the practical course 鈥淣euroscience鈥, which was part of the 3rd year Medical degree program at the Faculty of Medicine.

Articles

  • Article: BRAIN. 2024;:1099-1105
    Akkuratov EE; Sorrell F; Picton LD; Sousa VC; Paucar M; Jans D; Svensson L-B; Lindskog M; Fritz N; Liebmann T; Sillar KT; Rosewich H; Svenningsson P; Brismar H; Miles GB; Aperia A
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;23(1):410
    Veenit V; Zhang X; Ambrosini A; Sousa V; Svenningsson P
  • Article: MOLECULAR PSYCHIATRY. 2021;26(7):3253-3265
    Sousa VC; Mantas I; Stroth N; Hager T; Pereira M; Jiang H; Jabre S; Paslawski W; Stiedl O; Svenningsson P
  • Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2020;374(1):126-133
    Becanovic K; de Donno MV; Sousa VC; Tedroff J; Svenningsson P
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(28):7906-7911
    Bigio B; Mathe AA; Sousa VC; Zelli D; Svenningsson P; McEwen BS; Nasca C
  • Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(10):1714-1722
    Stan TL; Sousa VC; Zhang X; Ono M; Svenningsson P
  • Article: NEUROBIOLOGY OF AGING. 2014;35(7):1680-1685
    Sousa VC; Vital J; Costenla AR; Batalha VL; Sebastiao AM; Ribeiro JA; Lopes LV
  • Article: TRANSLATIONAL PSYCHIATRY. 2014;4(6):e395
    Stan TL; Alvarsson A; Branzell N; Sousa VC; Svenningsson P
  • Article: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. 2014;121:82-87
    Schijven D; Sousa VC; Roelofs J; Olivier B; Olivier JDA
  • Article: PURINERGIC SIGNALLING. 2014;10(2):251-267
    Assaife-Lopes N; Sousa VC; Pereira DB; Ribeiro JA; Sebastiao AM
  • Journal article: JOURNAL OF CAFFEINE AND ADENOSINE RESEARCH. 2013;3(2):85-95
    Sousa VC; Ribeiro JA; Sebasti茫o AM
  • Article: NEUROPSYCHOPHARMACOLOGY. 2011;36(9):1823-1836
    Diogenes MJ; Costenla AR; Lopes LV; Jeronimo-Santos A; Sousa VC; Fontinha BM; Ribeiro JA; Sebastiao AM
  • Article: NEUROPSYCHOPHARMACOLOGY. 2011;36(2):472-487
    Sousa VC; Assaife-Lopes N; Ribeiro JA; Pratt JA; Brett RR; Sebastiao AM

All other publications

  • Conference publication: GASTROENTEROLOGY. 2024;166(5):s-605
    MacKay J; Jucaite A; Csel茅nyi Z; Johnstr枚m P; Dahl K; Schou M; Stenkrona P; Sousa VC; H枚gn盲sbacka A; Gonzalez MAC; Giffen P; Bouma G; Nys J; Br眉lls M; Duncan M; Larsson J; Lundahl A; Les KA; Bergare J; Elmore CS; Kiraga J; Bl茅 F-X; Fowler A; Belvisi MG; Marks DJ
  • Conference publication: JOURNAL OF CROHNS & COLITIS. 2024;18(Supplement_1):i263
    MacKay J; Jucaite A; Csel茅nyi Z; Johnstr枚m P; Dahl K; Schou M; Stenkrona P; Sousa V; Gonzalez MC; Giffen P; Bouma G; Nys J; Br眉lls M; Duncan M; Larsson J; Lundahl A; Les K; Bergare J; Elmore C; Kiraga J; Bl茅 FX; Fowler A; Belvisi M; Marks D
  • Conference publication: JOURNAL OF CROHNS & COLITIS. 2024;18:I260
    MacKay J; Jucaite A; Cselenyi Z; Johnstrom P; Dahl K; Schou M; Stenkrona P; Sousa V; Gonzalez MC; Giffen P; Bouma G; Nys J; Brulls M; Duncan M; Larsson J; Lundahl A; Les K; Bergare J; Elmore C; Kiraga J; Ble FX; Fowler A; Belvisi M; Marks D
  • Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:108437
    H枚gn盲sbacka A; Gonzalez MAC; Cselenyi Z; Jucaite A; Dahl K; Johnstrom P; Sousa V; Bergare J; Nys J; Gardiner P; Br眉lls M; Gehrmann U; Ble F-X; Les K; Elmore C; Mackay J; Halldin C; Marks D; Schou M
  • Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:S31-S32
    Hognasbacka A; Gonzalez MAC; Cselenyi Z; Jucaite A; Dahl K; Johnstrom P; Sousa V; Bergare J; Nys J; Gardiner P; Brulls M; Gehrmann U; Ble F-X; Les K; Elmore C; Mackay J; Halldin C; Marks D; Schou M
  • Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2023;50(SUPPL 1):S254
    Schou M; Pike A; Jucaite A; Johnstrom P; Gonzalez MC; Hognasbacka A; Dahl K; Ghosh A; Johannes J; Staniszewska A; Leo E; Hamerlik P; Davies B; Cosulich S; Swales J; Lawrence R; Squatrito M; Mueller N; Sousa V; Bartek J; Stragliotto G; Stenkrona P; Farde L; Halldin C; Cselenyi Z
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2016;26:S371-S372
    Mathe AA; Nikosjkov A; Sousa V; Weide-Fischer C; Lennartsson A; Wegener G; Svenningsson P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25:S97-S98
    Pereira M; Sousa V; Svenningsson P
  • Conference publication: NEUROPSYCHOPHARMACOLOGY. 2015;40:S152-S153
    Mathe A; Nikosjkov A; Sousa V; Weide-Fischer C; Lennartsson A; Wegener G; Svenningsson P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S259
    Pereira M; Sousa VC; Stan T; Fischer CW; Wegener G; Olivier JDA; Mathe AA; Svenningsson P
  • Conference publication: NEUROPSYCHOPHARMACOLOGY. 2013;38:S553-S554
    Mathe A; Sousa V; Fischer CW; Stan TL; Wegener G; Lennartsson A; Svenningsson P
  • Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2012;15:155
    Stan TL; Sousa V; Zhang X; Alvarsson A; Ono M; Svenningssson P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21:S408-S409
    Sousa VC; Zhang X; Qi H; El Yacoubi M; Vaugeois JM; Svenningsson P

Grants

  • Autoradiography Core facility
    Core facility anslag (SLL/KI)
    1 January 2019 - 31 December 2021
  • 鈥淢echanisms of HPA axis and circadian rhythm dysregulation, with implications for sleep disorders and major depression鈥
    Rut and Arvid Wolff Memorial Foundation
    18 November 2013 - 30 November 2014
  • 鈥淚nvestigation of gene-environment interactions and biochemical mechanisms in the onset and development of major depression鈥
    The Wenner-Gren Foundation
    1 January 2012 - 31 March 2014
  • short term grant for collaborative work at Strathclyde University
    European Cooperation in Science and Technology (COST)
    1 April 2010 - 30 June 2010
  • 鈥淐ross-talk mechanisms between adenosine and endocannabinoids鈥
    The Portuguese Foundation for Science and Technology (FCT)
    1 March 2006 - 31 March 2010

Employments

  • Senior Research Infrastructure Specialist, Department of Clinical Neuroscience, 探花精选, 2024-
  • Co-ordinator for StratNeuro, 探花精选, 2019-2023
  • Post-doctoral researcher, Neuropsychopharmacology, Department of Clinical Neuroscience, 探花精选, 2011-2014
  • Visiting Researcher, Neuropsychopharmacology, Department of Clinical Neuroscience, 探花精选, 2010-2011

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