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Jaakko Patrakka

Jaakko Patrakka

Researcher | Docent
Telephone: +46852483595
Visiting address: Nobels väg 7, 17165 Solna
Postal address: H5 Laboratoriemedicin, H5 Patologi Patrakka, 141 52 Huddinge
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About me

  • Adjunct Professor of Pathology at the Department of Laboratory Medicine as of
    1 September 2020. Primary position: Doctor at Karolinska University Hospital

Research

  • Jaakko Patrakka is a clinical pathologist and researches kidney function and
    the mecha- nisms of chronic kidney disease. More specifically he is studying
    glomeruli – the network of millions of capillaries in the kidneys that
    produces primary urine. Glomerular diseases are the most common cause of
    death by kidney failure. With a better understanding of glomeruli and their
    diseases, Jaakko Patrakka hopes to contribute to the development of new
    diagnostic and prognostic tools and new drugs.
    His research involves the use of genetic and molecular tools, and spans the
    mapping of mechanisms in animal models to the search for biomarkers in
    patient material. Single-cell sequencing has also enabled Jaakko Patrakka’s
    group to characterise different cell types in the kidneys’ heterogeneous
    tissue, which has led to the discovery of a previously unknown glomerular
    cell type.
    The group is also collaborating with AstraZeneca on the development of new
    drug candidates.

Articles

  • Journal article: SCIENTIFIC REPORTS. 2024;14(1):11850
    Dabaghie D; Charrin E; Tonelius P; Rosengren B; Korkut G; Granqvist AB; Lal M; Patrakka J
  • Article: KIDNEY INTERNATIONAL. 2023;103(6):1120-1130
    Unnersjoe-Jess D; Butt L; Hoehne M; Sergei G; Fatehi A; Witasp A; Wernerson A; Patrakka J; Hoyer PF; Blom H; Schermer B; Bozek K; Benzing T
  • Article: COMMUNICATIONS BIOLOGY. 2023;6(1):208
    Charrin E; Dabaghie D; Sen I; Unnersjoe Jess D; Moller-Hackbarth K; Burmakin M; Mencke R; Zambrano S; Patrakka J; Olauson H
  • Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(2):311-321
    Levin A; Schwarz A; Hulkko J; He L; Sun Y; Barany P; Bruchfeld A; Herthelius M; Wennberg L; Ebefors K; Patrakka J; Betsholtz C; Nystrom J; Molne J; Hultenby K; Witasp A; Wernerson A
  • Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2022;33(11):2008-2025
    Hada I; Shimizu A; Takematsu H; Nishibori Y; Kimura T; Fukutomi T; Kudo A; Ito-Nitta N; Kiuchi Z; Patrakka J; Mikami N; Leclerc S; Akimoto Y; Hirayama Y; Mori S; Takano T; Yan K
  • Article: KIDNEY INTERNATIONAL. 2022;101(4):752-765
    Zambrano S; He L; Kano T; Sun Y; Charrin E; Lal M; Betsholtz C; Suzuki Y; Patrakka J
  • Article: KIDNEY INTERNATIONAL. 2021;100(4):809-823
    Moller-Hackbarth K; Dabaghie D; Charrin E; Zambrano S; Genove G; Li X; Wernerson A; Lal M; Patrakka J
  • Article: NATURE COMMUNICATIONS. 2021;12(1):2141
    He B; Chen P; Zambrano S; Dabaghie D; Hu Y; Moller-Hackbarth K; Unnersjoe-Jess D; Korkut GG; Charrin E; Jeansson M; Bintanel-Morcillo M; Witasp A; Wennberg L; Wernerson A; Schermer B; Benzing T; Ernfors P; Betsholtz C; Lal M; Sandberg R; Patrakka J
  • Article: KIDNEY INTERNATIONAL. 2021;99(4):1010-1020
    Unnersjoe-Jess D; Butt L; Hoehne M; Witasp A; Kuehne L; Hoyer PF; Patrakka J; Brinkkoetter PT; Wernerson A; Schermer B; Benzing T; Scott L; Brismar H; Blom H
  • Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020;35(12):2059-2072
    Levin A; Reznichenko A; Witasp A; Liu P; Greasley PJ; Sorrentino A; Blondal T; Zambrano S; Nordstrom J; Bruchfeld A; Barany P; Ebefors K; Erlandsson F; Patrakka J; Stenvinkel P; Nystrom J; Wernerson A
  • Article: SCIENTIFIC REPORTS. 2020;10(1):20037
    Rodriguez PQ; Unnersjo-Jess D; Zambrano SS; Guo J; Moller-Hackbarth K; Blom H; Jahnukainen T; Ebarasi L; Patrakka J
  • Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2019;30(9):1573-1586
    Zambrano S; Moeller-Hackbarth K; Li X; Rodriguez PQ; Charrin E; Schwarz A; Nystrom J; Wernerson AO; Lal M; Patrakka J
  • Article: SCIENTIFIC REPORTS. 2019;9(1):8888
    Schwarz A; Moller-Hackbarth K; Ebarasi L; Jess DU; Zambrano S; Blom H; Wernerson A; Lel M; Patrakka J
  • Article: KIDNEY INTERNATIONAL. 2018;94(6):1099-1110
    Borestrom C; Jonebring A; Guo J; Palmgren H; Cederblad L; Forslow A; Svensson A; Soderberg M; Reznichenko A; Nystrom J; Patrakka J; Hicks R; Maresca M; Valastro B; Collen A
  • Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2018;29(6):1679-1689
    Ma X; Schwarz A; Sevilla SZ; Levin A; Hultenby K; Wernerson A; Lal M; Patrakka J
  • Article: KIDNEY INTERNATIONAL. 2018;93(4):1008-1013
    Unnersjo-Jess D; Scott L; Sevilla SZ; Patrakka J; Blom H; Brismar H
  • Article: SCIENTIFIC REPORTS. 2018;8(1):4712
    Zambrano S; Rodriguez PQ; Guo J; Moller-Hackbarth K; Schwarz A; Patrakka J
  • Article: PLOS ONE. 2018;13(8):e0202400
    Hamano S; Nishibori Y; Hada I; Mikami N; Ito-Nitta N; Fukuhara D; Kudo A; Xiao Z; Nukui M; Patrakka J; Tryggvason K; Yan K
  • Article: CLINICAL AND EXPERIMENTAL NEPHROLOGY. 2017;21(4):677-684
    Suvanto M; Patrakka J; Jahnukainen T; Sjostrom P-M; Nuutinen M; Arikoski P; Kataja J; Kestila M; Jalanko H
  • Article: CELL METABOLISM. 2017;25(3):713-726
    Falkevall A; Mehlem A; Palombo I; Sahlgren BH; Ebarasi L; He L; Ytterberg AJ; Olauson H; Axelsson J; Sundelin B; Patrakka J; Scotney P; Nash A; Eriksson U
  • Show more

All other publications

  • Review: FRONTIERS IN ENDOCRINOLOGY. 2018;9:409
    Lal MA; Patrakka J
  • Corrigendum: PLOS ONE. 2015;10(5):e0126079
    Perisic L; Rodriguez PQ; Hultenby K; Sun Y; Lal M; Betsholtz C; Uhlen M; Wernerson A; Hedin U; Pikkarainen T; Tryggvason K; Patrakka J
  • Corrigendum: DEVELOPMENTAL DYNAMICS. 2012;241(2):431
    Xiao Z; Patrakka J; Nukui M; Chi L; Niu D; Betsholtz C; Pikkarainen T; Vainio S; Tryggvason K
  • Corrigendum: JOURNAL OF CLINICAL INVESTIGATION. 2012;122(2):780
    Yaddanapudi S; Altintas MM; Kistler AD; Fernandez I; Moeller CC; Wei C; Peev V; Flesche JB; Forst A-L; Li J; Patrakka J; Xiao Z; Grahammer F; Schiffer M; Lohmueller T; Reinheckel T; Gu C; Huber TB; Ju W; Bitzer M; Rastaldi MP; Ruiz P; Tryggvason K; Shaw AS; Faul C; Sever S; Reiser J
  • Review: NATURE REVIEWS NEPHROLOGY. 2009;5(8):463-468
    Patrakka J; Tryggvason K
  • Review: TRENDS IN MOLECULAR MEDICINE. 2007;13(9):396-403
    Patrakka J; Tryggvason K
  • Editorial comment: CELL. 2006;125(2):221-224
    Tryggvason K; Pikkarainen T; Patrakka J
  • Review: NEW ENGLAND JOURNAL OF MEDICINE. 2006;354(13):1387-1401
    Tryggvason K; Patrakka J; Wartiovaara J
  • Review: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2006;17(3):813-822
    Tryggvason K; Patrakka J
  • Published conference paper: KIDNEY INTERNATIONAL. 2000;58(3):972-980
    Patrakka J; Kestilä M; Wartiovaara J; Ruotsalainen V; Tissari P; Lenkkeri U; Männikkö M; Visapää I; Holmberg C; Rapola J; Tryggvason K; Jalanko H

Employments

  • Researcher, Department of Laboratory Medicine, ̽»¨¾«Ñ¡, 2016-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2013

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