探花精选

New drug candidate under development

Oncopeptides has a new drug candidate for the treatment of a form of cancer of the blood, multiple myeloma, under development. KI Innovations played a key role in getting the project underway.

Picture on Rolf Lewensohn dressed in a blure shirt.
Rolf Lewensohn. Photo: H氓kan Lindgren.

was founded in 2000 by some of Sweden鈥檚 leading oncological, clinical and 探花精选 researchers. The innovation behind Oncopeptides builds on the development of a cytotoxin that searches for and targets a specific type of cancer cell. However, the development phase took longer than expected due to uncertainty surrounding its effectiveness.

鈥淲e then came into contact with the leading multiple myeloma research group at the Dana-Farber Cancer Institute, , that was able to confirm our results. They saw so much potential in the project that they wanted to take control of it completely. This spurred interest among Swedish investors and accelerated the pace of our work,鈥 explains , professor of oncology at 探花精选, and consultant at Karolinska University Hospital.

Capital was soon raised in Sweden to conduct Phase 1 and Phase 2 trials in co-operation with, among others, the Dana-Farber Cancer Institute.

Clinicians as a driving force

During Oncopeptides鈥 first three years of operation, Lewensohn served as CEO.

鈥淚t was an instructive journey that provided entirely new perspectives on the opportunities of achieving clinical benefit from discoveries, and showed how we can meet the university鈥檚 third responsibility, namely to work with society and industry.鈥

鈥淥ne of the strengths behind Oncopeptides was that development was led by clinicians,鈥 he says.

鈥淭his was a virtually unique situation because as it was us heading-up the project, we understood the potential that lay in the use of the drug. It was a major advantage to have awareness of the patient鈥檚 perspective.鈥

Oncopeptides was listed in 2017, and work is now underway on the upcoming Phase 3 clinical trial.

鈥淲e had early contact with KI Innovations who supported us with investment and contributed to business development and provided advice. We currently anticipate having a new drug ready in the next couple of years,鈥 says Lewensohn.

Quick facts

An incurable cancer

Every year, close to 700 people in Sweden contract myeloma, a bone marrow cancer. It is a chronic condition, which develops in considerably different ways between individuals. While the condition is incurable, survival rates have improved every year in the past 10 years, thanks to the large number of new drug treatments that have been developed.

SB
Content reviewer:
KI Kommunikati鈥
15-09-2024