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Hyperbarmedicin – Peter Lindholms forskargrupp

Vi studerar effekterna av syretryck hos patienter som behandlas med hyperbar syrebehandling och friska människor i extrema miljöer.

En bild av Anders Kjellberg och Peter Lindholm.

Hyperbaric oxygen therapy (HBOT) is a clinical method used for 14 different diagnoses where oxygen is given at 240-280 kPa (compared to breathing room air ~21kPa or breathing pure oxygen ~100kPa). The chamber is located at the Karolinska University Hospital in Solna.
 

Research projects

Hyperbaric Oxygen for Treatment of Long COVID syndrome; A Randomized, Placebo-Controlled, Double-Blind, Phase II Clinical Trial

Principal Investigator Anders Kjellberg
Contact Person: Anders Kjellberg
Coordinating Investigator: Peter Lindholm

Financial support: Swedish Research Council, The Swedish Heart Lung Foundation and Avtal om Läkarutbildning och Forskning (ALF).

A Randomized, Controlled, Open Label, Multicentre Clinical Trial to explore Safety and Efficacy of Hyperbaric Oxygen for preventing ICU admission, Morbidity and Mortality in Adult Patients With COVID-19

Coordinating investigator Anders Kjellberg

Sponsor representative Peter Lindholm

Contact:

Read more about the clinical trial 

Selected publications


Kjellberg A, Douglas J, Pawlik M T, Kraus M, Oscarsson N, Zheng X et al
BMJ Open, protocol


Kjellberg A, De Maio A, Lindholm P 
Med Hypotheses 2020 Nov;144():110224


Biomarkers in HBOT

PhD-project for Anders Kjellberg.
Main supervisor P. Lindholm.

Supervisors K.Rodriguez-Wallberge S.Catrina, X.Zheng and E.Weitzberg

Biomarkers for oxidative stress and HIF1 upregulation during Hyperbaric Oxygen and Ischemia Reperfusion Injury- a Translational project on Hyperbaric oxygen for Preconditioning.


Rich-Art study group

Local PI KI Anders Kjellberg. PI Niclas Oscarsson.

Selected publications


Oscarsson N, Müller B, Rosén A, Lodding P, Mölne J, Giglio D, et al
Lancet Oncol. 2019 Nov;20(11):1602-1614


Imaging and the lung in diving medicine

Selected publications


Lindholm P, Swenson ER, Martínez-Jiménez S, Guo HH
Am. J. Respir. Crit. Care Med. 2018 10;198(8):1088-1089


Schiffer TA, Lindholm P
Eur. J. Appl. Physiol. 2013 Mar;113(3):803-10


Lindholm P, Norris CM, Braver JM, Jacobson F, Ferrigno M
Respir Physiol Neurobiol 2009 Jun;167(2):189-94


Lindholm P, Ekborn A, Oberg D, Gennser M
J. Appl. Physiol. 2008 Apr;104(4):912-7


Lindholm P, Nyrén S
Eur. J. Appl. Physiol. 2005 Aug;94(5-6):646-51


Hypoxia and hyperoxia

Selected publications


Manselin TA, Södergård O, Larsen FJ, Lindholm P
Physiol Rep 2017 Jan;5(2):


Lindholm P, Lundgren CE
Undersea Hyperb Med ;33(6):463-7


Lindholm P, Gennser M
Eur. J. Appl. Physiol. 2005 Mar;93(5-6):701-7


Lindholm P, Sundblad P, Linnarsson D
J. Appl. Physiol. 1999 Dec;87(6):2122-7

Magnetic resonance imaging in pulmonary embolism (Dr Lindholms radiology research)

PhD-student: Deepa Gopalan

MD, PhD: Koshiar Medson

Selected publications


Gopalan D, Nordgren-Rogberg A, Le EPV, Pavey H, Tarkin J, Nyrén S, et al
J Am Heart Assoc 2020 Nov;9(21):e018075


Nyrén S, Nordgren Rogberg A, Vargas Paris R, Bengtsson B, Westerlund E, Lindholm P
Acta Radiol 2017 Mar;58(3):272-278


Rogberg AN, Gopalan D, Westerlund E, Lindholm P
Acta Radiol 2019 Nov;60(11):1576-1583


Medson K, Vargas-Paris R, Nordgren-Rogberg A, Sigbergsdottir A, Nyrén S, Lindholm P
Eur J Radiol Open 2019 ;6():315-319

Support our research

Publikationer

Utvalda publikationer

  • Article: BMJ OPEN. 2021;11(7):e046738
    Kjellberg A; Douglas J; Pawlik MT; Kraus M; Oscarsson N; Zheng X; Bergman P; Franberg O; Kowalski JH; Nyren SP; Silvanius M; Skold M; Catrina S-B; Rodriguez-Wallberg KA; Lindholm P
  • Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2020;9(21):e018075
    Gopalan D; Nordgren-Rogberg A; Le EPV; Pavey H; Tarkin J; Nyren S; Auger W; Lindholm P
  • Article: MEDICAL HYPOTHESES. 2020;144:110224
    Kjellberg A; De Maio A; Lindholm P
  • Article: ACTA RADIOLOGICA. 2019;60(11):1576-1583
    Rogberg AN; Gopalan D; Westerlund E; Lindholm P
  • Article: THE LANCET ONCOLOGY. 2019;20(11):1602-1614
    Oscarsson N; Muller B; Rosen A; Lodding P; Molne J; Giglio D; Hjelle KM; Vaagbo G; Hyldegaard O; Vangedal M; Salling L; Kjellberg A; Lind F; Ettala O; Arola O; Seeman-Lodding H
  • Article: EUROPEAN JOURNAL OF RADIOLOGY OPEN. 2019;6:315-319
    Medson K; Vargas-Paris R; Nordgren-Rogberg A; Sigbergsdottir A; Nyren S; Lindholm P
  • Editorial comment: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2018;198(8):1088-1089
    Lindholm P; Swenson ER; Martinez-Jimenez S; Guo HH
  • Article: ACTA RADIOLOGICA. 2017;58(3):272-278
    Nyren S; Rogberg AN; Paris RV; Bengtsson B; Westerlund E; Lindholm P
  • Article: PHYSIOLOGICAL REPORTS. 2017;5(2):e13119
    Manselin TA; Södergård O; Larsen FJ; Lindholm P
  • Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2013;113(3):803-810
    Schiffer TA; Lindholm P
  • Article: RESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY. 2009;167(2):189-194
    Lindholm P; Norris CMJ; Braver JM; Jacobson F; Ferrigno M
  • Article: JOURNAL OF APPLIED PHYSIOLOGY. 2008;104(4):912-917
    Lindholm P; Ekborn A; Oeberg D; Gennser M
  • Article: UNDERSEA AND HYPERBARIC MEDICINE. 2006;33(6):463-467
    Lindholm P; Lundgren CEG
  • Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2005;94(5-6):646-651
    Lindholm P; Nyrén S
  • Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2005;93(5-6):701-707
    Lindholm P; Gennser M
  • Article: JOURNAL OF APPLIED PHYSIOLOGY. 1999;87(6):2122-2127
    Lindholm P; Sundblad P; Linnarsson D

Medarbetare och kontakt

Gruppledare

Alla medarbetare i gruppen

Collaborations

  • , Professor, Department of Oncology-Pathology, ̽»¨¾«Ñ¡.
  • Nicklas Oscarsson, MD, Sahlgrenska Academy, Gothemburg.
  • , Lecturer/senior physician, Research group leader of the group Growth and Metabolism, Department of Molecular Medicine and Surgery, Karolinska Insitutet.
  • , Lecturer senior, adjunct, Department of Clinical Neuroscience, ̽»¨¾«Ñ¡.
  • , Senior lab manager, Department of Molecular Medicine and Surgery, Ì½»¨¾«Ñ¡.
  • , Affiliated to research, Department of Physiology and Pharmacology, Ì½»¨¾«Ñ¡.
  • , Professor/senior physician of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Ì½»¨¾«Ñ¡.
  • MD, PhD, postdoc, Department of Oncology-Pathology, ̽»¨¾«Ñ¡.
  • , Associate Professor and Senior Lecturer,  Division of Physiotherapy, Department of NVS, ̽»¨¾«Ñ¡ and the Medical Unit of Occupational Therapy and Physiotherapy at the Karolinska University Hospital.
  • , Affiliated to research, Department of Medicine at ̽»¨¾«Ñ¡.
  • , Affiliated to research, Department of Medicine at ̽»¨¾«Ñ¡.
  • Mikael Runold, Överläkare Karolinska Universitetssjukhuset
  • , MD, PhD, Professor, Center for Infectious Medicine, ̽»¨¾«Ñ¡, and Karolinska University Hospital.
  • , M.D., Ph.D., FUHM, Assistant Professor (retired), Karolinska Insitutet, Physician Emeritus, Karolinska University hospital, Senior Consultant Hyperbaric Medicine
  • , Professor i kardiologi vid institutionen för medicin, ̽»¨¾«Ñ¡
  • Carl-Johan Sundberg, Professor i molekylär och tillämpad arbetsfysiologi vid institutionen för fysiologi och farmakologi, samt prefekt vid institutionen för lärande, informatik, management och etik (LIME), ̽»¨¾«Ñ¡
Nyckelord:
Anestesi och intensivvård Fysiologi Radiologi och bildbehandling
PL
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2024-03-22