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Yizhou Hu

Yizhou Hu

Visiting address: Solnav盲gen 9, 6C, 17177 Stockholm
Postal address: C2 Medicinsk biokemi och biofysik, C2 Molekyl盲r neurobiologi Ernfors, 171 77 Stockholm
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About me

  • Molecular system biology, work on molecular biochemistry and translational
    medicine since 2005, coding since 2008.
    * Ph.D., Pathology (Oncology and Molecular Cell Biology), Translational
    Cancer Biology Program, Faculty of Medicine, University of Helsinki,
    Finland
    * M.Sc., Genetics (Human Genetics and Bioinformatics), Faculty of Biological
    and Environmental Sciences, University of Helsinki, Finland
    * B.Sc., Biotechnology (Medical Biotechnology), Life Science College of
    Soochow University, Suzhou, China

Research

  • Nervous system tumor, single-cell/spatial technology, developmental
    neurobiology, and deep learning.
    *Recent Publications: *
    * Neogenin suppresses tumor progression and metastasis via inhibiting
    Merlin/YAP signaling [1], Cell Death Discov., 2023
    * Neural network learning defines glioblastoma features to be of neural
    crest perivascular or radial glia lineages [2], Sci Adv., 2022
    * Single cell transcriptional zonation of human psoriasis skin identifies an
    alternative immunoregulatory axis conducted by skin resident cells
    [3], Cell Death Dis., 2021
    *Software:*
    1) SWAPLINE, Single-cell Weighted Assignment and Projection on developmental
    LINEages [4]
    2) scCAMEL, learning-based single-cell analysis toolkits,
    website: [5]
    *Dataset visualization:*
    1. Single cell transcriptional zonation of human psoriasis skin identifies
    an alternative immunoregulatory axis conducted by skin resident cells, Cell
    Death Dis., 2021
    Website: [6]
    [1]
    [2]
    [3]
    [4] _GBMlineage2022
    [5]
    [6]

Selected publications

  • Journal article: NATURE NEUROSCIENCE. 2024;27(12):2326-2340
    Yu H; Nagi SS; Usoskin D; Hu Y; Kupari J; Bouchatta O; Yan H; Cranfill SL; Gautam M; Su Y; Lu Y; Wymer J; Glanz M; Albrecht P; Song H; Ming G-L; Prouty S; Seykora J; Wu H; Ma M; Marshall A; Rice FL; Li M; Olausson H; Ernfors P; Luo W
  • Article: SCIENCE. 2024;385(6712):eado6593
    Fatt MP; Zhang M-D; Kupari J; Altinkok M; Yang Y; Hu Y; Svenningsson P; Ernfors P
  • Article: CELL DEATH DISCOVERY. 2023;9(1):47
    Hu X; Li L; Li F; Yang Y; An J; Zhou X; Zhang R; Shi L; Zhao H; Wang J; Hu Y; Xu Y
  • Article: SCIENCE ADVANCES. 2022;8(23):eabm6340
    Hu Y; Jiang Y; Behnan J; Ribeiro MM; Kalantzi C; Zhang M-D; Lou D; Haring M; Sharma N; Okawa S; Del Sol A; Adameyko I; Svensson M; Persson O; Ernfors P
  • Article: CELL DEATH AND DISEASE. 2021;12(5):450
    Gao Y; Yao X; Zhai Y; Li L; Li H; Sun X; Yu P; Xue T; Li Y; Hu Y
  • Article: NATURE COMMUNICATIONS. 2021;12(1):2141
    He B; Chen P; Zambrano S; Dabaghie D; Hu Y; Moller-Hackbarth K; Unnersjoe-Jess D; Korkut GG; Charrin E; Jeansson M; Bintanel-Morcillo M; Witasp A; Wennberg L; Wernerson A; Schermer B; Benzing T; Ernfors P; Betsholtz C; Lal M; Sandberg R; Patrakka J
  • Article: NATURE COMMUNICATIONS. 2021;12(1):1510
    Kupari J; Usoskin D; Parisien M; Lou D; Hu Y; Fatt M; Lonnerberg P; Spangberg M; Eriksson B; Barkas N; Kharchenko PV; Lore K; Khoury S; Diatchenko L; Ernfors P

Articles

  • Journal article: JOURNAL OF DERMATOLOGICAL TREATMENT. 2024;35(1):2337264
    Gao Y; Li C; Tong M; Hu Y; Li Y
  • Journal article: NEURO-ONCOLOGY. 2024;26(10):1878-1894
    Chen Y; Zhuo R; Sun L; Tao Y; Li G; Zhu F; Xu Y; Wang J; Li Z; Yu J; Yin H; Wu D; Li X; Fang F; Xie Y; Hu Y; Wang H; Yang C; Shi L; Wang X; Zhang Z; Pan J
  • Article: BMC CANCER. 2024;24(1):89
    Li L; Xia S; Zhao Z; Deng L; Wang H; Yang D; Hu Y; Ji J; Huang D; Xin T
  • Article: NATURE METABOLISM. 2023;5(7):1188-1203
    Barreby E; Strunz B; Nock S; Naudet L; Shen JX; Johansson H; Soennerborg I; Ma J; Urgard E; Pallett LJ; Hu Y; Fardellas A; Azzimato V; Vankova A; Levi L; Morgantini C; Maini MK; Stal P; Rosshart SP; Coquet JM; Nowak G; Naeslund E; Lauschke VM; Ellis E; Bjoerkstroem NK; Chen P; Aouadi M
  • Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1265517
    Gao Y; Na M; Yao X; Li C; Li L; Yang G; Li Y; Hu Y
  • Article: STEM CELL REPORTS. 2022;17(5):1089-1104
    Muhl L; He L; Sun Y; Mae MA; Pietila R; Liu J; Genove G; Zhang L; Xie Y; Leptidis S; Mocci G; Stritt S; Osman A; Anisimov A; Hemanthakumar KA; Rasanen M; Hansson EM; Bjorkegren J; Vanlandewijck M; Blomgren K; Makinen T; Peng X-R; Hu Y; Ernfors P; Arnold TD; Alitalo K; Lendahl U; Betsholtz C
  • Article: BMC CANCER. 2018;18(1):1215
    Li L; Huang Y; Gao Y; Shi T; Xu Y; Li H; Hyytiainen M; Keski-Oja J; Jiang Q; Hu Y; Du Z

All other publications

  • Preprint: BIORXIV. 2023;BIORXIV
    Yu H; Usoskin D; Nagi SS; Hu Y; Kupari J; Bouchatta O; Cranfill SL; Gautam M; Su Y; Lu Y; Wymer J; Glanz M; Albrecht P; Song H; Ming G-L; Prouty S; Seykora J; Wu H; Ma M; Rice FL; Olausson H; Ernfors P; Luo W
  • Preprint: BIORXIV. 2020
    Kupari J; Usoskin D; Lou D; Parisien M; Hu Y; Fatt M; L枚nnerberg P; Sp氓ngberg M; Eriksson B; Barkas N; Kharchenko PV; Lor茅 K; Khoury S; Diatchenko L; Ernfors P

Grants

  • Decoding the molecular and cellular regulatory logic in malignant brain cancer
    脜ke Wibergs Foundation
    1 January 2025 - 31 December 2026
  • Decoding the molecular and cellular regulatory logic in glioblastoma
    脜ke Wibergs Foundation
    1 January 2024 - 31 December 2025
  • Decoding the gene regulatory programme in glioblastoma
    脜ke Wibergs Foundation
    1 January 2023 - 31 December 2024
  • Identifying the perivascular propagating cells of Glioblastoma
    SSMF
    1 March 2021 - 28 February 2023

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