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Sebastian Lewandowski

Sebastian Lewandowski

Senior Research Specialist
Visiting address: CMM, Visionsgatan 18, 5 tr, 17176 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Harris Lewandowski, 171 77 Stockholm
Part of:

About me

  • 2018 - ongoing - Team Leader at the Department of Clinical Neuroscience and Center for Molecular Medicine
    2008 - 2018 - Postdoc. Ulf Eriksson group, ̽»¨¾«Ñ¡
    2005 - PhD degree. Nencki Institute of Experimental Biology, Warsaw, Poland
    1997 - MSc degree. University of Gdansk, Poland

Research

  • Our team studies cellular mechanisms of cerebrovascular injury mechanisms in ALS neurodegeneration to find novel clinical biomarkers and therapeutic solutions.

    Publication highlight:
    MÃ¥nberg A. et al. Nature Medicine, April 2021


    Nature Medicine News and Views, April 2021


    Karolinska Institute Press release.


    Our web resource for cell-specific gene expression in ALS:


    We look at how blood vessel dysfunction and vascular remodelling lead to
    increased severity of Amyotrophic Lateral Sclerosis (ALS) and FTD using
    bioinformatics, in-vivo rodent models and clinical samples. We collaborate
    with the leading neurology centres in Europe and US including UZ Leuven in
    Belgium, Univ. Utrecht in Holland, Ulm Univ. in Germany and UCSD in San
    Diego. Our results lead to novel off-label drug applications to therapy and
    biomarkers in neurodegeneration including ALS, stroke and multiple sclerosis.

    We offer Master student, PhD and Postdoc positions to highly motivated and 
    enthusiastic researchers. For details, send an email to sebastian.lewandowski@ki.se

Teaching

  • 2020 - ongoing - PhD course director  
    2008 - ongoing - Lecturer and group discussion leader in the Biomedicine program
    2018 - ongoing - MSc student supervision 

Articles

  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2025;:e171077
    Protzmann J; Zeitelhofer M; Stefanitsch C; Torrente D; Adzemovic MZ; Matjunins K; Randel SJ; Lewandowski SA; Muhl L; Eriksson U; Nilsson I; Su EJ; Lawrence DA; Fredriksson L
  • Journal article: EBIOMEDICINE. 2024;110:105470
    Lewandowski SA; Kular L; Jagodic M
  • Journal article: CEREBRAL CIRCULATION - COGNITION AND BEHAVIOR. 2024;6:100049
    Månberg A; Skene N; Sanders F; Szczepinska A; Remnestål J; De Vocht J; Anink J; Vergunst-Bosch H; Rodriguez-Vieitez E; Gilthorpe J; Harris R; Aronica E; Van Damme P; Ludolph A; Veldink J; Ingre C; KTH PN; Lewandowski S
  • Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2023;11:1169962
    Hipke K; Pitter B; Hruscha A; van Bebber F; Modic M; Bansal V; Lewandowski SA; Orozco D; Edbauer D; Bonn S; Haass C; Pohl U; Montanez E; Schmid B
  • Article: NEUROTHERAPEUTICS. 2021;18(3):1963-1979
    Peters S; Kuespert S; Wirkert E; Heydn R; Jurek B; Johannesen S; Hsam O; Korte S; Ludwig FT; Mecklenburg L; Mrowetz H; Altendorfer B; Poupardin R; Petri S; Thal DR; Hermann A; Weishaupt JH; Weis J; Aksoylu IS; Lewandowski SA; Aigner L; Bruun T-H; Bogdahn U
  • Article: NATURE MEDICINE. 2021;27(4):640-646
    Manberg A; Skene N; Sanders F; Trusohamn M; Remnestal J; Szczepinska A; Aksoylu IS; Lonnerberg P; Ebarasi L; Wouters S; Lehmann M; Olofsson J; von Gohren Antequera I; Domaniku A; De Schaepdryver M; De Vocht J; Poesen K; Uhlen M; Anink J; Mijnsbergen C; Vergunst-Bosch H; Hubers A; Klappe U; Rodriguez-Vieitez E; Gilthorpe JD; Hedlund E; Harris RA; Aronica E; Van Damme P; Ludolph A; Veldink J; Ingre C; Nilsson P; Lewandowski SA
  • Journal article: DISEASE MODELS & MECHANISMS. 2020;13(5):dmm045310
    Crivello M; Hogg MC; Jirstrom E; Halang L; Woods I; Rayner M; Coughlan KS; Lewandowski SA; Prehn JHM
  • Article: DISEASE MODELS & MECHANISMS. 2019;12(8):dmm040238
    Crivello M; Hogg MC; Jirstrom E; Halang L; Wood I; Rayner M; Coughlan KS; Lewandowski SA; Prehn JHM
  • Article: NEUROBIOLOGY OF DISEASE. 2018;119:26-40
    Nonneman A; Criem N; Lewandowski SA; Nuyts R; Thal DR; Pfrieger FW; Ravits J; Van Damme P; Zwijsen A; Van Den Bosch L; Robberecht W
  • Article: NEUROPHARMACOLOGY. 2018;133:503-511
    Crivello M; O'Riordan SL; Woods I; Cannon S; Halang L; Coughlan KS; Hogg MC; Lewandowski SA; Prehn JHM
  • Article: ACTA NEUROPATHOLOGICA. 2016;131(3):453-464
    Lewandowski SA; Nilsson I; Fredriksson L; Lonnerberg P; Muhl L; Zeitelhofer M; Adzemovic MZ; Nichterwitz S; Lawrence DA; Hedlund E; Eriksson U
  • Article: PLOS ONE. 2012;7(6):e38760
    Abrams MB; Nilsson I; Lewandowski SA; Kjell J; Codeluppi S; Olson L; Eriksson U
  • Article: CARCINOGENESIS. 2009;30(4):575-579
    Vedin L-L; Lewandowski SA; Parini P; Gustafsson J-A; Steffensen KR
  • Article: ONCOGENE. 2008;27(7):1019-1032
    Williams C; Edvardsson K; Lewandowski SA; Stroem A; Gustafsson J-A
  • Article: ONCOGENE. 2005;24(30):4789-4798
    Lewandowski SA; Thiery J; Jalil A; Leclercq G; Szczylik C; Chouaib S
  • Article: INTERNATIONAL JOURNAL OF CANCER. 2004;110(6):783-787
    Skrzypczak M; Bieche I; Szymczak S; Tozlu S; Lewandowski S; Girault I; Radwanska K; Szczylik C; Jakowicki JA; Lidereau R; Kaczmarek L
  • Article: CANCER LETTERS. 2001;164(2):143-148
    Giermasz A; Nowis D; Jalili A; Basak G; Marczak M; Makowski M; Czajka A; Mlynarczuk I; Hoser G; Stok T; Lewandowski S; Jakóbisiak M

All other publications

  • Review: FRONTIERS IN VETERINARY SCIENCE. 2023;10:1135282
    Cannon AE; Zurrer WE; Zejlon C; Kulcsar Z; Lewandowski S; Piehl F; Granberg T; Ineichen BV
  • Review: FRONTIERS IN NEUROLOGY. 2022;13:947347
    Zejlon C; Nakhostin D; Winklhofer S; Pangalu A; Kulcsar Z; Lewandowski S; Finnsson J; Piehl F; Ingre C; Granberg T; Ineichen BV
  • Preprint: RESEARCH SQUARE. 2021
    Zejlon C; Nakhostin D; Winklhofer S; Pangalu A; Lewandowski S; Finnsson J; Piehl F; Ingre C; Granberg T; Ineichen BV
  • Preprint: BIORXIV. 2021
    Zeitelhofer M; Stefanitsch C; Protzmann J; Torrente D; Adzemovic MZ; Lewandowski SA; Muhl L; Eriksson U; Nilsson I; Su EJ; Lawrence DA; Fredriksson L
  • Corrigendum: NATURE MEDICINE. 2021;27(7):1308
    Manberg A; Skene N; Sanders F; Trusohamn M; Remnestal J; Szczepinska A; Aksoylu IS; Lonnerberg P; Ebarasi L; Wouters S; Lehmann M; Olofsson J; von Gohren Antequera I; Domaniku A; De Schaepdryver M; De Vocht J; Poesen K; Uhlen M; Anink J; Mijnsbergen C; Vergunst-Bosch H; Hubers A; Klappe U; Rodriguez-Vieitez E; Gilthorpe JD; Hedlund E; Harris RA; Aronica E; Van Damme P; Ludolph A; Veldink J; Ingre C; Nilsson P; Lewandowski SA
  • Conference publication: INTERNATIONAL JOURNAL OF STROKE. 2020;15(1_SUPPL):624-625
    Zeitelhofer M; Stefanitsch C; Adzemovic M; Sue J; Lewandowski S; Muhl L; Nilsson I; Lawrence D; Fredriksson L
  • Review: PHARMACOLOGY & THERAPEUTICS. 2016;167:108-119
    Lewandowski SA; Fredriksson L; Lawrence DA; Eriksson U
  • Editorial comment: EXPERIMENTAL NEUROLOGY. 2014;257:182-185
    Abrams MB; Nilsson I; Kjell J; Lewandowski S; Codeluppi S; Eriksson U; Olson L
  • Book chapter: HORMONAL CARCINOGENESIS IV. 2005;p. 314-320
    Skrzypczak M; Zagulska-Szymczak S; Lidereau R; Bieche I; Lewandowski S; Radwanska K; Szczylik C; Vidaud M; Jakowicki JA; Kaczmarek L
  • Review: FEBS LETTERS. 2002;524(1-3):1-5
    Lewandowski S; Kalita K; Kaczmarek L

Grants

  • Swedish Research Council
    1 January 2022 - 31 December 2024
  • Swedish Brain Foundation
    1 January 2022 - 1 January 2024
  • Molecular phenotyping of brain metabolism in asymptomatic ALS/FTD patients
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    1 January 2022 - 1 January 2024
  • Frick Foundation
    1 January 2021 - 1 January 2022

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