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Rongrong Fan

Rongrong Fan

Principal Researcher | Docent
Visiting address: Blickagången 16, 14152 Flemingsberg
Postal address: H7 Medicin, Huddinge, H7 BioNut Fan, 171 77 Stockholm

About me

  • Lab page:
    /en/bionut/liver-and-monocyte-remodelling-in-non-alcoholic-fatty-liver-disease-and-cardiovascular

    Research grants:

    Swedish research council (Vetenskapsrådet)

    EFSD / Novo Nordisk Future Leaders Award 


  • Cancerfonden

    The Rolf Luft Grant for Instrumentation 


  • SRP diabetes 

  • KI faculty-funded senior researcher 

  • CIMED
    NOVO NORDISK Foundation
    KI Doctoral funding
    Ã…ke Wibergs Stiftelse
    Diabetes Wellness Sverige Foundation
    EFSD / Lilly research fellowship
    KI foundation

    Commission of trust:
    Editorial board: Frontiers in Endocrinology 2021-.
    Guest editor: Frontiers in Endocrinology 2020-2021.
    Steering Committee: lipoprotein research networks in KI south campus
    (supported by CIMED).
    Grant evaluation task for: ANR, VR, FWF, KID, etc
    Invited reviewer in: Nat Com, JCI, eLife, JBC, FASEB J, Diabetologia, etc.
    Organizing committee and chairs for domestic and international conferences.

Research

  • My research combines the phenotypic/clinical analysis with multi-OMICs approaches to understand the fundamental question of how over-nutritional
    signals alter chromatin remodelling to promote metabolic disease development. We have so far analyzed different patient samples in the transcriptomic, cistromic and epigenomic levels and identified a group of interesting candidates involved in species-conserved and disease-relevant regulation of glucose and lipid metabolism. Of particular interest is the transcription factor coregulator GPS2, the dysregulation of which is associated with de-repressed inflammation and impaired lipid oxidation pathways, leading to type 2 diabetes and liver disease progression.
    The ongoing research activity involves further investigation of the coregulator-based mechanisms in the genomic and epigenomic level in various
    disease contexts. Understanding such pathways is crucial for better deciphering disease mechanisms which is ultimately required for identifying
    novel targets with diagnostic and intervention potential.

Teaching

  • Main supervisor of 3 ongoing PhD student and 1 postdoc
    Cosupervisor of 1 ongoing PhD student and 2 completed PhD students
    Project supervisor of 5 bachelor students and 2 Master student
    More than 200 teaching hours in Bachelor, Master and PhD courses

    Master level course director
    Professional university pedagogy training (equivalent to more than 5 weeks)

Articles

  • Article: CELL METABOLISM. 2024;:S1550-4131(24)00413-3
    Lin K; Wei L; Wang R; Li L; Song S; Wang F; He M; Pu W; Wang J; Wazir J; Cao W; Yang X; Treuter E; Fan R; Wang Y; Huang Z; Wang H
  • Article: SCIENCE ADVANCES. 2024;10(1):eadi2689
    Ludzki AC; Hansen M; Zareifi D; Jalkanen J; Huang Z; Omar-Hmeadi M; Renzi G; Klingelhuber F; Boland S; Ambaw YA; Wang N; Damdimopoulos A; Liu J; Jernberg T; Petrus P; Arner P; Krahmer N; Fan R; Treuter E; Gao H; Ryden M; Mejhert N
  • Article: NUCLEIC ACIDS RESEARCH (NAR). 2023;51(3):1067-1086
    Huang Z; Efthymiadou A; Liang N; Fan R; Treuter E
  • Article: NATURE COMMUNICATIONS. 2023;14(1):224
    Lin J; Sun S; Zhao K; Gao F; Wang R; Li Q; Zhou Y; Zhang J; Li Y; Wang X; Du L; Wang S; Li Z; Lu H; Lan Y; Song D; Guo W; Chen Y; Gao F; Zhao Y; Fan R; Guan J; He W
  • Article: BIOMATERIALS RESEARCH. 2022;26(1):64
    Ma J; Xu X; Fu C; Xia P; Tian M; Zheng L; Chen K; Liu X; Li Y; Yu L; Zhu Q; Yu Y; Fan R; Jiang H; Li Z; Yang C; Xu C; Long Y; Wang J; Li Z
  • Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2022;37(7):723-733
    Yuan S; Chen J; Li X; Fan R; Arsenault B; Gill D; Giovannucci EL; Zheng J-S; Larsson SC
  • Article: STAR PROTOCOLS. 2022;3(2):101338
    Huang Z; Wang C; Treuter E; Fan R
  • Article: CELL COMMUNICATION AND SIGNALING. 2022;20(1):45
    Zhuang T; Wang B; Tan X; Wu L; Li X; Li Z; Cai Y; Fan R; Yang X; Zhang C; Xia Y; Niu Z; Liu B; Cao Q; Ding Y; Zhou Z; Huang Q; Yang H
  • Article: MOLECULAR CELL. 2021;81(5):953-968.e9
    Huang Z; Liang N; Goni S; Damdimopoulos A; Wang C; Ballaire R; Jager J; Niskanen H; Han H; Jakobsson T; Bracken AP; Aouadi M; Venteclef N; Kaikkonen MU; Fan R; Treuter E
  • Article: ENVIRONMENTAL TOXICOLOGY. 2020;35(11):1170-1178
    Mai X; Zhou F; Lin P; Lin S; Gao J; Ma Y; Fan R; Ting W; Huang C; Yin D; Kang Z
  • Article: CARDIOVASCULAR DIABETOLOGY. 2020;19(1):182
    Ling W; Huang Y; Huang Y-M; Fan R-R; Sui Y; Zhao H-L
  • Article: CELL BIOLOGY INTERNATIONAL. 2019;43(8):940-953
    Kang Z; Zeng J; Zhang T; Lin S; Gao J; Jiang C; Fan R; Yin D
  • Article: NATURE COMMUNICATIONS. 2019;10(1):1684
    Liang N; Damdimopoulos A; Goni S; Huang Z; Vedin L-L; Jakobsson T; Giudici M; Ahmed O; Pedrelli M; Barilla S; Alzaid F; Mendoza A; Schroder T; Kuiper R; Parini P; Hollenberg A; Lefebvre P; Francque S; Van Gaal L; Staels B; Venteclef N; Treuter E; Fan R
  • Article: THE FASEB JOURNAL. 2019;33(2):1631-1643
    Huang Z; Liang N; Damdimopoulos A; Fan R; Treuter E
  • Article: METHODS IN MOLECULAR BIOLOGY. 2019;1951:167-178
    Liang N; Fan R; Goñi S; Treuter E
  • Article: DIABETOLOGY AND METABOLIC SYNDROME. 2019;11(1):94
    Sui Y; Kong X; Fan R; Ye Y; Mai H; Zhuo S; Lu W; Ruan P; Fang S; Yang T
  • Article: CELL REPORTS. 2018;24(11):2957-2971.e6
    Drareni K; Ballaire R; Barilla S; Mathew MJ; Toubal A; Fan R; Liang N; Chollet C; Huang Z; Kondili M; Foufelle F; Soprani A; Roussel R; Gautier J-F; Alzaid F; Treuter E; Venteclef N
  • Article: ONCOGENE. 2018;37(19):2586-2600
    He H; Sinha I; Fan R; Haldosen L-A; Yan F; Zhao C; Dahlman-Wright K
  • Article: ANTIOXIDANTS AND REDOX SIGNALING. 2017;27(13):962-976
    Zhou Y; Chung ACK; Fan R; Lee HM; Xu G; Tomlinson B; Chan JCN; Kong APS
  • Article: NATURE MEDICINE. 2016;22(7):780-791
    Fan R; Toubal A; Goni S; Drareni K; Huang Z; Alzaid F; Ballaire R; Ancel P; Liang N; Damdimopoulos A; Hainault I; Soprani A; Aron-Wisnewsky J; Foufelle F; Lawrence T; Gautier J-F; Venteclef N; Treuter E
  • Article: DIABETOLOGIA. 2013;56(2):423-433
    Kang ZF; Deng Y; Zhou Y; Fan RR; Chan JCN; Laybutt DR; Luzuriaga J; Xu G
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2013;123(1):362-379
    Toubal A; Clement K; Fan R; Ancel P; Pelloux V; Rouault C; Veyrie N; Hartemann A; Treuter E; Venteclef N
  • Article: CELL TRANSPLANTATION. 2013;22(1):147-158
    Xu H; Tsang KS; Chan JCN; Yuan P; Fan R; Kaneto H; Xu G
  • Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY. 2011;43(4):525-534
    Li X-L; Chen T; Wong Y-S; Xu G; Fan R-R; Zhao H-L; Chan JCN
  • Article: PLOS ONE. 2011;6(5):e20443
    Fan R; Kang Z; He L; Chan J; Xu G
  • Article: DIABETES, OBESITY AND METABOLISM. 2010;12(9):815-824
    Fan R; Li X; Gu X; Chan JCN; Xu G
  • Article: AMERICAN JOURNAL OF PHYSIOLOGY - RENAL PHYSIOLOGY. 2010;298(2):F391-F400
    Sui Y; Zhao H-L; Fan R-R; Guan J; He L; Lee HM; Chan JCN; Tong PCY
  • Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY. 2009;41(7):1526-1535
    Li X-L; Xu G; Chen T; Wong Y-S; Zhao H-L; Fan R-R; Gu X-M; Tong PCY; Chan JCN
  • Article: KIDNEY INTERNATIONAL. 2008;74(4):467-477
    Zhao H-L; Sui Y; Guan J; He L; Zhu X; Fan R-R; Xu G; Kong APS; Ho CS; Lai FMM; Rowlands DK; Chan JCN; Tong PCY
  • Show more

All other publications

  • Review: ACTA PHARMACOLOGICA SINICA. 2024;45(10):1997-2010
    Wang M-M; Zhao Y; Liu J; Fan R-R; Tang Y-Q; Guo Z-Y; Li T
  • Editorial comment: FRONTIERS IN ENDOCRINOLOGY. 2021;12:828635
    Fan R; Pineda-Torra I; Venteclef N
  • Review: THE FASEB JOURNAL. 2020;34(7):8796-8809
    Kang Z; Fan R
  • Preprint: SSRN ELECTRONIC JOURNAL. 2020
    Yang X; Sui Y; Liu F; Kang Z; Wu S; Zhao J; Zhang Y; Wang H; Sun Y; Zhao P; Zhang Y; Zhao Y; Wang J; Xiao F; Zhan Q; Wang X; Fan R; Duan J
  • Review: FRONTIERS IN ENDOCRINOLOGY. 2019;10:411
    Liang N; Jakobsson T; Fan R; Treuter E
  • Review: FEBS LETTERS. 2017;591(19):2959-2977
    Treuter E; Fan R; Huang Z; Jakobsson T; Venteclef N
  • Review: HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. 2016;233:95-135
    Giudici M; Goni S; Fan R; Treuter E

Grants

  • Swedish Research Council
    1 January 2024 - 31 December 2026
  • From epigenetics to functional epigenetics: investigating enhancers and silencers in human metabolic tissues
    Novo Nordisk Foundation
    1 January 2022 - 31 December 2026
  • Swedish Research Council
    1 January 2020 - 31 December 2023
  • Epigenomic medicine in type 2 diabetes and atherosclerosis: targeting macrophage enhancers
    Novo Nordisk Foundation
    1 January 2020 - 31 December 2022

Employments

  • Principal Researcher, Department of Medicine, Huddinge, ̽»¨¾«Ñ¡, 2024-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2022

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