Petter H枚glund
Professor/Senior Physician | Head of department | Docent
E-mail: petter.hoglund@ki.se
Telephone: +46852482914
Mobile phone: +46705596201
Visiting address: , Huddinge/Stockholm
Postal address: H7 Medicin, Huddinge, H7 Hematologi H枚glund, 171 77 Stockholm
About me
- Head of Department/prefekt at the Department for Medicine, Huddinge (MedH) and research Group Leader for Immunological tolerance and transfusion immunology at HERM, KI.
I am a professor of basic immunology, especially clinically applied cell therapy and transplantation, at the Department of Medicine, Huddinge. I moved here in 2011, after two decades working as a scientist at the Karolinska Campus in Solna.
I gained my PhD in 1993 at the Department of Tumor Biology, 探花精选, KI and I finished my 探花精选 training in 1996. From 1996 to 1999, I worked as a postdoctoral scientist at the Institut de G茅n茅tique et de Biologie Mol茅culaire et Cellulaire (IGBMC), Strasbourg, France.
In 1999, I was awarded the Young Investigator Award by the Cancer Research Institute in the USA, and received the Swedish Society of Medicine's young senior research fellow prize in 2001. In 2003, I became associate professor (docent) in immunology at KI and from 2011, obtained my professorship.
During the period 1999-2010 I conducted research at MTC, KI, with funding from the Wenner-Gren Foundations, the Swedish Cancer Society, Vetenskapsr氓det, 探花精选 and the Karolinska University Hospital. My main research interests are the regulation of Natural Killer (NK) cell specificity.
Academic honours, awards and prizes
Appointed Professor of basal immunology, especially clinically applied cell therapy and transplantation at 探花精选 in 2011.
Research
- NK cells (natural killer cells) are a type of lymphocyte that is considered part of the non-adaptive immune system and can recognize and kill virus-infected cells and cancer cells. When the immune system recovers after a stem cell transplantation, NK cells can contribute to important anti-cancer effects in patients with leukaemia - a reaction called Graft-versus-Leukaemia (GvL).
One of my research aims is to understand the molecular mechanisms that govern the formation of NK cells in the body. We are particularly interested in how NK cell are 鈥渆ducated鈥 in vivo, how they learn to distinguish self from non self and which mechanisms that regulate the responsiveness of NK cells. More recently, my group has also started to expore the role of NK cells s immune barriers to blod and platelet transfusions in patients.
Articles
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;100(2):e13374
- Article: HLA. 2024;103(3):e15429
- Article: BLOOD ADVANCES. 2024;8(3):571-580
- Journal article: CLINICAL IMMUNOLOGY COMMUNICATIONS. 2023;3:31-36
- Article: TRANSFUSION. 2023;63(11):2040-2051
- Article: SCIENCE SIGNALING. 2023;16(780):eabq0752
- Article: HEMASPHERE. 2023;7(4):e872
- Article: INTERNATIONAL JOURNAL OF IMMUNOGENETICS. 2023;50(2):65-74
- Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(11):e005577
- Article: TRANSFUSION. 2022;62(8):1636-1642
- Article: BLOOD. 2022;139(5):704-716
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:854312
- Article: FRONTIERS IN PUBLIC HEALTH. 2022;10:1073318
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;196(1):224-233
- Article: MALARIA JOURNAL. 2021;20(1):441
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(1):e13037
- Article: LIFE SCIENCE ALLIANCE. 2021;4(4):e202000723
- Article: TRANSFUSION. 2021;61(4):1222-1234
- Article: TRANSFUSION. 2021;61(2):464-473
- Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;92(6):e12997
- Article: TRANSFUSION MEDICINE AND HEMOTHERAPY. 2020;47(5):385-395
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504
- Article: TRANSFUSION. 2019;59(3):945-952
- Article: LEUKEMIA. 2019;33(2):522-527
- Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249
- Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2018;88(6):e12731
- Article: VOX SANGUINIS. 2018;113(8):779-786
- Article: TRANSFUSION. 2018;58(11):2657-2668
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(2):212-224
- Article: THROMBOSIS RESEARCH. 2018;162:69-76
- Article: FRONTIERS IN IMMUNOLOGY. 2018;9:3173
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142
- Article: NATURE COMMUNICATIONS. 2017;8(1):224
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;85(6):417-424
- Article: NATURE COMMUNICATIONS. 2017;8:15627
- Journal article: ISBT SCIENCE SERIES. 2017;12(1):148-153
- Article: TRANSFUSION MEDICINE. 2017;27(1):43-51
- Article: VOX SANGUINIS. 2017;112(1):33-39
- Article: SCIENTIFIC REPORTS. 2016;6:37996
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1758-1769
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2016;434:9-15
- Article: IMMUNOLOGY AND CELL BIOLOGY. 2016;94(2):177-184
- Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123
- Article: TRANSFUSION. 2016;56(2):370-382
- Article: TRANSFUSION. 2014;54(3):602-612
- Article: BLOOD TRANSFUSION. 2013;11(3):456-459
- Article: FRONTIERS IN IMMUNOLOGY. 2013;4:65
- Article: ACTA DERMATO-VENEREOLOGICA. 2012;92(6):609-614
- Article: JOURNAL OF IMMUNOLOGY. 2012;188(5):2218-2226
- Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2011;11(11):2472-2482
- Article: BIOPHYSICAL JOURNAL. 2011;101(5):1257-1269
- Article: JOURNAL OF IMMUNOLOGY. 2011;187(2):760-773
- Article: PLOS ONE. 2010;5(10):e13174
- Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2010;25(8):2764-2771
- Article: JOURNAL OF IMMUNOLOGY. 2010;184(5):2272-2280
- Article: JOURNAL OF AUTOIMMUNITY. 2010;34(1):66-72
- Article: PLOS ONE. 2009;4(6):e6046
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2009;119(5):1251-1263
- Article: IMMUNITY. 2009;30(3):337-347
- Article: BLOOD. 2009;113(11):2434-2441
- Article: JOURNAL OF IMMUNOLOGY. 2009;182(3):1460-1468
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2934-2937
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):3191-3199
- Article: MOLECULAR IMMUNOLOGY. 2008;45(11):3059-3064
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2007;37(2):516-527
- Article: JOURNAL OF IMMUNOLOGY. 2006;177(5):2908-2916
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2006;36(2):264-266
- Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2005;307(1-2):73-81
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2005;201(7):1145-1155
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(48):16873-16878
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(11):3091-3101
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(1-2):134-142
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(6):1646-1653
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(1):71-78
- Article: INTERNATIONAL IMMUNOLOGY. 2004;16(1):1-11
- Article: IMMUNOLOGY. 2003;110(3):313-321
- Article: CANCER IMMUNITY. 2003;3:6
- Journal article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2003;10(2-4):183-192
- Article: BULLETIN OF MATHEMATICAL BIOLOGY. 2003;65(2):199-218
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2001;194(10):1519-1530
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(2):525-533
- Article: INTERNATIONAL IMMUNOLOGY. 1999;11(8):1239-1245
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 1999;189(2):331-339
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(12):4198-4206
- Article: JOURNAL OF IMMUNOLOGY. 1998;161(11):6133-6138
- Article: DIABETES. 1998;47(8):1207-1211
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 1998;187(3):427-432
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(1):370-378
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 1997;186(3):353-364
- Article: TRANSPLANTATION. 1997;63(1):119-123
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(1):342-345
- Article: CARCINOGENESIS. 1995;16(10):2515-2521
- Article: TRANSPLANTATION. 1995;60(3):281-286
- Article: MOLECULAR IMMUNOLOGY. 1995;32(11):789-794
- Article: CANCER RESEARCH. 1995;55(9):1911-1916
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(5):1286-1291
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All other publications
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(1):e13347
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;98(6):e13340
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;97(6)
- Review: HEMASPHERE. 2023;7(1):e814
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(6)
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(5)
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(3)
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(2)
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13199
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(6)
- Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2022;97(6):E207-E210
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(5):e13173
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(4):e13165
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(3):e13147
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(2):e13141
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(1):e13127
- Letter: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(10):2531-2534
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(1)
- Review: FRONTIERS IN IMMUNOLOGY. 2021;12:640578
- Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(7):E163-E166
- Editorial comment: HEMASPHERE. 2020;4(3):e406
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;91(4):e12878
- Review: TRANSFUSION MEDICINE REVIEWS. 2019;33(4):231-235
- Editorial comment: TRANSFUSION. 2019;59(6):1945-1952
- Review: PEDIATRIC BLOOD AND CANCER. 2018;65(12):e27361
- Letter: TRANSPLANTATION. 2017;101(5):e190-e192
- Review: EXPERT REVIEW OF HEMATOLOGY. 2016;9(5):479-487
- Review: CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY. 2016;395:95-114
- Review: IMMUNOLOGICAL REVIEWS. 2015;267(1):167-177
- Other: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2012;61(4):587-591
- Review: NATURE REVIEWS IMMUNOLOGY. 2010;10(10):724-734
- Review: CURRENT OPINION IN IMMUNOLOGY. 2009;21(6):634-640
- Review: TRENDS IN IMMUNOLOGY. 2009;30(4):143-149
- Corrigendum: MOLECULAR IMMUNOLOGY. 2008;45(14):3863
- Review: SEMINARS IN CANCER BIOLOGY. 2006;16(5):393-403
- Editorial comment: SEMINARS IN CANCER BIOLOGY. 2006;16(5):331-332
- Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2006;2006(317):pe2
- Review: CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY. 2006;298:259-277
- Review: TRENDS IN IMMUNOLOGY. 2005;26(11):613-618
- Published conference paper: MOLECULAR IMMUNOLOGY. 2005;42(4):397-403
- Review: SEMINARS IN IMMUNOLOGY. 2003;15(6):317-324
- Review: IMMUNOLOGICAL REVIEWS. 1999;169:139-146
- Review: IMMUNOLOGICAL REVIEWS. 1997;155:11-28
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Grants
- Swedish Research Council1 January 2022 - 31 December 2024
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Transfusion treatment of leukemia patients: predictors of transfusion outcome and immunological consequences of chronic transfusion dependence.Swedish Cancer Society1 January 2018
- Swedish Research Council1 June 2017 - 30 June 2017
- Molecular and clinical studies of the development and function of NK cells.Swedish Cancer Society1 January 2017
- Molecular and clinical studies of the development and function of NK cells.Swedish Cancer Society1 January 2016
- Molecular and clinical studies of the development and function of NK cells.Swedish Cancer Society1 January 2015
- Swedish Research Council1 January 2013 - 31 December 2015
- Swedish Research Council1 January 2012 - 31 December 2016
Employments
- Professor/Senior Physician, Department of Medicine, Huddinge, 探花精选, 2023-
Degrees and Education
- Docent, 探花精选, 2003
- University Medical Degree, 探花精选, 1997
Leadership and responsibility assignments
- Head of department, Department of Medicine, Huddinge, 探花精选, 2021-