̽»¨¾«Ñ¡

Mattias Svensson

Mattias Svensson

Principal Researcher | Docent
Visiting address: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postal address: H7 Medicin, Huddinge, H7 CIM Svensson, 171 77 Stockholm
Part of:

About me

  • Expertise in preclinical research in the field of immunology and infection,
    myeloid immune cells, host pathogen interactions and cell biology.
    Conduct translational projects based on preclinical science. This includes
    participation in the two international projects, PerAID and PERMIT, which
    focus on personalized medicine for infectious diseases (2019-2024).
    Particular interest in: Infection and immunology, as well as human myeloid
    immune cells such as monocytes, dendritic cells and macrophages in acute and
    chronic tissue inflammation.
    Current position: Research group leader, associate professor.
    Is Director of Doctoral Education at the Department of Medicine, Huddinge and
    Chairman of the Dissertation Committee at ̽»¨¾«Ñ¡.
    1995, MSc, Biology, Lund University, Sweden
    2000, PhD, Immunology, Lund University, Sweden
    2001-2004, Post doctoral Fellow, London School of Hygiene and Tropical
    Medicin, London, UK
    2010, Associate Professor, Immunology, ̽»¨¾«Ñ¡, Sweden

Research

  • Our research group [1] at the Center for Infectious Medicine (CIM [2]),
    Department of Medicine, Huddinge conducts research aimed at understanding how
    the tissue microenvironment affects bacterial properties, immune cell
    responses and immune-mediated pathology with special focus on tissue-specific
    cells' ability to form myeloid cell functions in bacterial infections and
    chronic inflammatory conditions.
    We strive to identify proteins and metabolites that are important for
    tissue-specific cells, such as fibroblasts, to shape the microenvironment for
    the function of myeloid immune cells and the specific properties of bacteria.
    The goal is to:
    1. Develop customized human organotypic models for disease mechanism
    identification, biomarker detection, and validation of interventions in sever
    bacterial infectious diseases
    2. Utilize identified disease mechanisms to develop tailored therapy and
    implement personalized medicine in sever infectious diseases.
    3. Identify central host-derived mediators which in the tissue environment
    drives bacteria behavior and characteristics, such as biofilm formation and
    persistence.
    Of particular interest are the two gram-positive bacteria Streptococcus
    pyogenes and Staphylococcus aureus. Both of these gram-positive bacteria can
    cause very aggressive invasive infections such as toxic shock, necrotizing
    pneumonia and necrotizing fasciitis which are associated with significant
    morbidity and mortality.
    [1] /en/medh/mattias-svensson-group-studies-of-tissue-microbiology-and-immunology
    [2] /en/medh/center-for-infectious-medicine-cim

Articles

  • Article: JOURNAL OF BIOMEDICAL SCIENCE. 2024;31(1):26
    Toelken LA; Paulikat AD; Jachmann LH; Reder A; Salazar MG; Medina LMP; Michalik S; Voelker U; Svensson M; Norrby-Teglund A; Hoff KJ; Lammers M; Siemens N
  • Article: NATURE COMMUNICATIONS. 2024;15(1):1752
    Kvedaraite E; Lourda M; Mouratidou N; Duking T; Padhi A; Moll K; Czarnewski P; Sinha I; Xagoraris I; Kokkinou E; Damdimopoulos A; Weigel W; Hartwig O; Santos TE; Soini T; Van Acker A; Rahkonen N; Tullberg MF; Ringqvist E; Buggert M; Jorns C; Lindforss U; Nordenvall C; Stamper CT; Unnersjoe-Jess D; Akber M; Nadisauskaite R; Jansson J; Vandamme N; Sorini C; Grundeken ME; Rolandsdotter H; Rassidakis G; Villablanca EJ; Idestroem M; Eulitz S; Arnell H; Mjoesberg J; Henter J-I; Svensson M
  • Article: PHARMACEUTICS. 2024;16(1):117
    Quinones-Vico MI; Fernandez-Gonzalez A; Ubago-Rodriguez A; Moll K; Norrby-Teglund A; Svensson M; Gutierrez-Fernandez J; Torres JM; Arias-Santiago S
  • Article: HAEMATOLOGICA. 2023;108(9):2422-2434
    Hagey DW; Kvedaraite E; Akber M; Goergens A; Javadi J; Greenwood TVB; Bjorklund C; Akefeldt SO; Hannegard-Hamrin T; Arnell H; Dobra K; Herold N; Svensson M; El Andaloussi S; Henter J-I; Lourda M
  • Article: JOURNAL OF BIOMEDICAL SCIENCE. 2023;30(1):52
    Shumba P; Sura T; Moll K; Chakrakodi B; Toelken L; Hossmann J; Hoff K; Hyldegaard O; Nekludov M; Svensson M; Arnell P; Skrede S; Norrby-Teglund A; Siemens N
  • Article: NATURE COMMUNICATIONS. 2023;14(1):4008
    Movert E; Bolarin JS; Valfridsson C; Velarde J; Skrede S; Nekludov M; Hyldegaard O; Arnell P; Svensson M; Norrby-Teglund A; Cho KH; Elhaik E; Wessels MR; Raberg L; Carlsson F
  • Article: CELL REPORTS MEDICINE. 2023;4(5):101038
    Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Idestrom M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjosberg J
  • Article: CLINICAL IMMUNOLOGY. 2023;249:109276
    Rath E; Medina LMP; Jahagirdar S; Mosevoll KA; Damas JK; Madsen MB; Svensson M; Hyldegaard O; dos Santos VAPM; Saccenti E; Norrby-Teglund A; Skrede S; Bruun T
  • Article: RESPIRATORY RESEARCH. 2023;24(1):62
    Palma Medina LM; Babacic H; Dzidic M; Parke A; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgard J; Moll K; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-JK; Sandberg J; Gredmark-Russ S; Rooyackers O; Svensson MJ; Chambers BI; Eriksson L; Pernemalm MK; Bjorkstrom N; Aleman S; Ljunggren H-G; Klingstrom J; Stralin K; Norrby-Teglund A
  • Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
    Ljunggren H-G; Heggernes Ask E; Cornillet Jeannin M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio Gomez A; Dzidic M; Filipovic I; Flodstrom-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Eriksson LI; Aleman S; Malmberg K-J; Stralin K; Bjorkstrom NK
  • Article: AMERICAN JOURNAL OF PATHOLOGY. 2022;192(4):653-670
    Ashenafi S; Muvva JR; Mily A; Snall J; Zewdie M; Chanyalew M; Rehn A; Rahman S; Aseffa G; Bekele A; Aderaye G; Lema B; Svensson M; Brighenti S
  • Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510
    Cornillet M; Strunz B; Rooyackers O; Ponzetta A; Chen P; Muvva JR; Akber M; Buggert M; Chambers BJ; Dzidic M; Filipovic I; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Parrot T; Perez-Potti A; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Eriksson LI; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK
  • Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2021;65(11):e0065821-10.1128/aac.00621
    Bergsten H; Medina LMP; Morgan M; Moll K; Skutlaberg DH; Skrede S; Wajima T; Svensson M; Norrby-Teglund A
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
    Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LMP; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgard J; Moll K; Garcia M; Maleki KT; Klingstrom J; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sonnerborg A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(14):149523
    Medina LMP; Rath E; Jahagirdar S; Bruun T; Madsen MB; Stralin K; Unge C; Hansen MB; Arnell P; Nekludov M; Hyldegaard O; Lourda M; Santos VAPMD; Saccenti E; Skrede S; Svensson M; Norrby-Teglund A
  • Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(4):1315-1321
    Kvedaraite E; Lourda M; Han H; Tesi B; Mitchell J; Idestrom M; Mouratidou N; Rassidakis G; Greenwood TVB; Cohen-Aubart F; Jadersten M; Akefeldt SO; Svensson M; Kannourakis G; Bryceson YT; Haroche J; Henter J-I
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
    Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
  • Article: EMBO MOLECULAR MEDICINE. 2020;12(11):e12695
    Subramanian K; Iovino F; Tsikourkitoudi V; Merkl P; Ahmed S; Berry SB; Aschtgen M-S; Svensson M; Bergman P; Sotiriou GA; Henriques-Normark B
  • Article: SCIENTIFIC REPORTS. 2020;10(1):17444
    Gorchs L; Ahmed S; Mayer C; Knauf A; Moro CF; Svensson M; Heuchel R; Rangelova E; Bergman P; Kaipe H
  • Article: CELL. 2020;183(1):158-168.e14
    Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
  • Show more

All other publications

  • Editorial comment: CLINICAL INFECTIOUS DISEASES. 2020;71(7):1772-1775
    Bergsten H; Madsen MB; Bergey F; Hyldegaard O; Skrede S; Arnell P; Oppegaard O; Itzek A; Perner A; Svensson M; Norrby-Teglund A
  • Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2020;191(1):115-119
    Lourda M; Wideskold S; Kvedaraite E; Gavhed D; Akber M; von Bahr Greenwood T; Svensson M; Olsson-Akefeldt S; Henter J-I
  • Review: FRONTIERS IN MEDICINE. 2020;7:537
    Berry SB; Haack AJ; Theberge AB; Brighenti S; Svensson M
  • Editorial comment: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2020;1294:V-VI
    Norrby-Teglund A; Svensson M; Skrede S
  • Review: CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY. 2018;430:29-54
    Svensson M; Chen P
  • Letter: BLOOD. 2016;128(9):1302-1305
    Lourda M; Olsson-Akefeldt S; Gavhed D; Nygell UA; Berlin G; Laurencikas E; Greenwood TVB; Svensson M; Henter J-I
  • Review: FRONTIERS IN MICROBIOLOGY. 2015;6:388
    Gustafsson R; Svensson M; Fogdell-Hahn A
  • Editorial comment: NATURE GENETICS. 2013;45(2):116-118
    Jagodic M; Stridh P; Gad AKB; Paine A; Udekwu KI; Sjoholm LK; Svensson M; Pan-Hammarstrom Q
  • Review: PHARMACEUTICALS. 2010;3(8):2733-2750
    Svensson M; Chen P; Hammarfjord O
  • Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2008;1150:213-216
    Jacobson S; Kumagai-Braesch M; Tibell A; Svensson M; Flodstroem-Tullberg M
  • Review: TRENDS IN IMMUNOLOGY. 2006;27(12):580-587
    Svensson M; Kaye PM
  • Review: IMMUNOLOGICAL REVIEWS. 2004;201:239-253
    Kaye PM; Svensson M; Ato M; Maroof A; Polley R; Stager S; Zubairi S; Engwerda CR
  • Published conference paper: FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY. 2000;27(4):313-320
    Yrlid U; Svensson M; Johansson C; Wick MJ
  • Review: BEHRING INSTITUTE MITTEILUNGEN. 1997;(98):197-211
    Svensson M; Pfeifer J; Stockinger B; Wick MJ

Grants

  • Swedish Research Council
    1 January 2024 - 31 December 2026
  • Swedish Research Council
    1 January 2019 - 31 July 2019
  • Swedish Research Council
    1 January 2014 - 31 December 2017
  • Swedish Research Council
    1 January 2010 - 31 December 2012
  • Swedish Research Council
    1 January 2010 - 31 December 2012
  • Swedish Research Council
    1 January 2009 - 31 December 2009

Employments

  • Principal Researcher, Department of Medicine, Huddinge, ̽»¨¾«Ñ¡, 2022-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2010

News from KI

Events from KI