̽ѡ

Mattias Larsson

Mattias Larsson

Researcher | Docent
Visiting address: Widerströmska huset Tomtebodavägen 18 A, plan 3, 17165 Solna
Postal address: K9 Global folkhälsa, K9 GPH Alfvén Lönnroth, 171 77 Stockholm
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About me

  • • Medical Director, Family Medical Practice, International Clinic, Hanoi, Vietnam
    • Associate Professor, Department of Global Public Health, ̽ѡ
    • Honorary Professor, Hanoi Medical University

Research

  • My main area of research is “how people can use antimicrobials with optimal effect and minimal resistance development”.

    In 2003, I defended my PhD thesis at Karolinska Institute titled “Antibiotic use and resistance Assessing and Improving Utilization and Provision of Antibiotics and Other Drugs in Vietnam”. (). We have then followed the antibiotic use and antibiotic resistance situation in Vietnam.

    In 2000-2002 I was the joint national coordinator for another the EU-funded RCT assessing antimicrobial use and resistance among 3200 children in four communities in Peru and Bolivia where we found high and increasing rates of E. coli resistance to common antibiotics.

    Since 2011 I have surveyed Hospital acquired infections (HAI) and Carbapenem Resistant Enterobacteriasae (CRE) in Vietnamese hospitals. One study among 2233 patients in 12 Vietnamese hospitals showed that 52% were colonized with CRE. Being colonised has significant correlation to HAI, increased time of hospital care, increased crude mortality and costs. An admission CRE screening and cohort care project in pediatric ICU's could significantly decrease CRE acquisition from 90% to 48%, HAI incidence, duration of hospital stay and costs. I have worked with Vietnamese MoH to assess IPC measures as basis for policy making. Now implementing an EU project, JPI-AMR admission and discharge CRE screening, cohort care in hospital and a randomized controlled trial (RCT) to decrease CRE transmission in households and community.

    From 2006 to 2010 I was the Principal Investigator for “A RCT to assess antiretroviral treatment strategies in relation to adherence, resistance and virological failure” (DOTARV) implemented in Quang Ninh, Vietnam. My research students in the project, Dr. Do Duy Cuong defended his thesis in October 2012 with the title: “Antiretroviral therapy among HIV-infected persons in North-eastern Vietnam: Impact of peer support on virologic failure and mortality in a cluster randomized controlled trial” He is now head of the Infectious Disease Unit in Hanoi’s largest hospital Bach Mai. Dr. Vu Van Tam, defended with: Enhanced Antiretroviral Treatment support in relation to Quality of Life and Virological failure in low-income setting: a cluster RCT in Quang Ninh, Vietnam. He is now head of Uong Bi Hospital Infectious Disease Unit. We have also done RCT in pediatric and adolescent HIV cohorts to improve ART adherence and decrease virological, immunological and clinical treatment failure in HCMC, Hanoi, Hai Phong and Quang Ninh.

Teaching

  • Teacher at Global Health course for Medical students: Coordinator VT 2001, Five times with the students to Medical college, Thiruvanantupuram, Kerala, India (autumn 1998, autumn 2002, VT 2004, autumn 2005, autumn 2006), two times to Muhimbili Medical University, Dar Es Salaam, Tanzania, spring 2001 and spring 2008, Laos VT 2013, Uganda VT 2017.

    Initiated the Global Health Course for Medical students from ̽ѡ in Vietnam, two weeks of field visits and bedside teaching in Quang Nam/Binh Dinh and Hanoi, and in Vietnam 12 times since spring 2009 until 2023.

    Initiated and organised Global Pediatric Course 2016-18 with and Hospital Acquired Infection (HAI) and antibiotic resistance 2017, both with Vietnam National Children's Hospital, Tropical Medicine Course 2018 with Hospital for Tropical Diseases, HCMC.

    Coordinator for Global Health master Course Introduction Course fall 2022.

Articles

  • Article: JGH OPEN. 2023;7(12):916-922
    Nguyen LT; Le TD; Hoang LB; Vu VT; Nguyen TD; Luu HTM; Do PN; Nguyen AV; Dao LV; Larsson M; Olson L; Dao HV
  • Article: PLOS MEDICINE. 2023;20(6):e1004179
    Russell NJ; Stohr W; Plakkal N; Cook A; Berkley JA; Adhisivam B; Agarwal R; Ahmed NU; Balasegaram M; Ballot D; Bekker A; Berezin EN; Bilardi D; Boonkasidecha S; Carvalheiro CG; Chami N; Chaurasia S; Chiurchiu S; Colas VRF; Cousens S; Cressey TR; de Assis ACD; Dien TM; Ding Y; Dung NT; Dong H; Dramowski A; Madhusudhan DS; Dudeja A; Feng J; Glupczynski Y; Goel S; Goossens H; Hao DTH; Khan MI; Huertas TM; Islam MS; Jarovsky D; Khavessian N; Khorana M; Kontou A; Kostyanev T; Laoyookhon P; Lochindarat S; Larsson M; De Luca M; Malhotra-Kumar S; Mondal N; Mundhra N; Musoke P; Mussi-Pinhata MM; Nanavati R; Nakwa F; Nangia S; Nankunda J; Nardone A; Nyaoke B; Obiero CW; Owor M; Ping W; Preedisripipat K; Qazi S; Qi L; Ramdin T; Riddell A; Romani L; Roysuwan P; Saggers R; Roilides E; Saha SK; Sarafidis K; Tusubira V; Thomas R; Velaphi S; Vilken T; Wang X; Wang Y; Yang Y; Zunjie L; Ellis S; Bielicki JA; Walker AS; Heath PT; Sharland M
  • Journal article: FRONTIERS IN PUBLIC HEALTH. 2023;11:1110903
    Tran-Quang K; Nguyen-Thi-Dieu T; Tran-Do H; Pham-Hung V; Nguyen-Vu T; Tran-Xuan B; Larsson M; Duong-Quy S
  • Article: JAC-ANTIMICROBIAL RESISTANCE. 2022;4(2):dlac038
    Nguyen TPY; Nguyen TN; Doan HP; Nguyen TTD; Nguyen TBV; Bach TK; Vo BH; Larsson M; Olson L; Campbell J; Nguyen PNQ; Pham TD; Carrique-Mas J
  • Article: EXPERT REVIEW OF ANTI-INFECTIVE THERAPY. 2022;20(3):445-456
    Cook A; Sharland M; Yau Y; Bielicki J
  • Article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2022;59(2):106496
    Sriram KK; Ekedahl E; Ngoc TBH; Sewunet T; Berglund B; Lundberg L; Nematzadeh S; Nilsson M; Nilsson LE; Le NK; Dien MT; Hanberger H; Olson L; Larsson M; Giske CG; Westerlund F
  • Article: PLOS ONE. 2022;17(10):e0274419
    Sewunet T; Sriram KK; Ha HN; Sithivong N; Ngoc TBH; Sychareun V; Nengmongvang K; Larsson M; Olson L; Westerlund F; Giske CG
  • Article: PEDIATRICS INTERNATIONAL. 2022;64(1):e14853
    Khai TQ; Hung TD; Van PH; Trung NV; Bach TX; Larsson M; Sy D-Q; Thuy N-T
  • Article: ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL. 2021;10(1):162
    Berglund B; Ngoc TBH; Lundberg L; Ngai KL; Tarnberg M; Nilsson M; Bornefall E; Dung TKK; Welander J; Hai TL; Olson L; Dien TM; Nilsson LE; Larsson M; Hanberger H
  • Article: ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL. 2021;10(1):128
    Garpvall K; Duong V; Linnros S; Quoc TN; Mucchiano D; Modeen S; Lagercrantz L; Edman A; Le NK; Huong T; Hoang NTB; Le HT; Khu DT; Tran DM; Phuc PH; Hanberger H; Olson L; Larsson M
  • Journal article: TNU JOURNAL OF SCIENCE AND TECHNOLOGY. 2021;226(10):261-267
    Hiền NT; Loan LTH; Lâm NV; Hương TTT; Larsson M; Olson L; Chúc NTK; Toàn TK
  • Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(6):1916-1923
    Larsson M; Hoa QN; Olson L; Toan KT; Trung VN; Chuc TKN
  • Article: BMC INFECTIOUS DISEASES. 2021;21(1):472
    Long HN; Huong LTN; Tran BX; Larsson M; Rocha LEC; Thorson A; Stromdahl S
  • Article: EMERGING INFECTIOUS DISEASES. 2021;27(1):10-17
    Cuong DD; Vuong MN; An VN; Tra TD; Tuan QN; Phuong TT; Olson L; Larsson M
  • Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2020;109(12):2685-2691
    Pham NTH; Le NDT; Le NK; Nguyen KD; Larsson M; Olson L; Tran DM
  • Article: MICROBIOLOGYOPEN. 2020;9(12):e1130
    Tran TC; Pham BT; Pham VH; Ngo TA; Hanberger H; Larsson M; Olson L
  • Article: ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH. 2020;32(8):469-470
    Tran TC; Ngo TA; Nguyen TD; Olson L; Larsson M
  • Article: BMC PUBLIC HEALTH. 2020;20(1):1387
    Nguyen LH; Nguyen HLT; Larsson M; Tran BX; Stein ML; Rocha LEC; Stroemdahl S
  • Article: AMERICAN JOURNAL OF MEN'S HEALTH. 2020;14(3):1557988320926743
    Linh VPD; Quan HN; Ishizaki A; Larsson M; Nhung TPV; Cuong DD; Olson L; Thanh TD
  • Journal article: WORLD JOURNAL OF AIDS. 2020;10(03):186-194
    Tran CT; Pham DT; Nguyen DT; Linus O; Mattias L
  • Show more

All other publications

  • Preprint: RESEARCH SQUARE. 2023
    Pham NT; TT QB; Tran DM; Larsson M; Pham MP; Olson L
  • Preprint: MEDRXIV. 2022
    Russell N; Stöhr W; Plakkal N; Cook A; Berkley JA; Adhisivam B; Agarwal R; Balasegaram M; Ballot D; Bekker A; Berezin EN; Bilardi D; Boonkasidecha S; Carvalheiro CG; Chaurasia S; Chiurchiu S; Cousens S; Cressey TR; Dien TM; Ding Y; Dramowski A; Madhusudhan D; Dudeja A; Feng J; Glupczynski Y; Goossens H; Huertas TM; Islam MS; Jarovsky D; Khavessian N; Khorana M; Kostyanev T; Larsson M; De Luca M; Malhotra-Kumar S; Mussi-Pinhata MM; Nanavati R; Nangia S; Nankunda J; Nardone A; Nyaoke B; Obiero CW; Owor M; Ping W; Preedisripipat K; Qazi S; Ramdin T; Riddell A; Roilides E; Saha SK; Sarafidis K; Thomas R; Velaphi S; Vilken T; Wang Y; Yang Y; Zunjie L; Ellis S; Bielicki J; Walker AS; Heath PT; Sharland M
  • Preprint: SSRN ELECTRONIC JOURNAL. 2021
    Russell N; Stöhr W; Plakkal N; Cook A; Berkley JA; Adhisivam B; Agarwal R; Balasegaram M; Ballot D; Bekker A; Berezin EN; Bilardi D; Boonkasidecha S; Carvalheiro CG; Chaurasia S; Chiurchiu S; Cousens S; Cressey TR; Dien TM; Ding Y; Dramowski A; Madhusudhan D; Dudeja A; Feng J; Glupczynski Y; Goossens H; Islam MS; Jarovsky D; Khavessian N; Khorona M; Kostyanev T; Larsson M; De Luca M; Malhotra-Kumar S; Mussi-Pinhata MM; Nanavati R; Nangia S; Nankunda J; Nyaoke B; Obiero CW; Owor M; Ping W; Preedisripipat K; Qazi S; Ramdin T; Riddell A; Roilides E; Saha S; Sarafidis K; Thomas R; Velaphi SC; Vilken T; Wang Y; Yang Y; Zunjie L; Ellis S; Bielicki J; Walker S; Heath PT; Sharland M
  • Preprint: SSRN ELECTRONIC JOURNAL. 2021
    Russell N; Stöhr W; Plakkal N; Cook A; Berkley JA; Adhisivam B; Agarwal R; Balasegaram M; Ballot D; Bekker A; Berezin EN; Bilardi D; Boonkasidecha S; Carvalheiro CG; Chaurasia S; Chiurchiu S; Cousens S; Cressey TR; Dien TM; Ding Y; Dramowski A; Ds M; Dudeja A; Feng J; Glupczynski Y; Goossens H; Islam MS; Jarovsky D; Khavessian N; Khorona M; Kostyanev T; Larsson M; De Luca M; Malhotra-Kumar S; Mussi-Pinhata MM; Nanavati R; Nangia S; Nankunda J; Nyaoke B; Obiero CW; Owor M; Ping W; Preedisripipat K; Qazi S; Ramdin T; Riddell A; Roilides E; Saha S; Sarafidis K; Thomas R; Velaphi SC; Vilken T; Wang Y; Yang Y; Zunjie L; Ellis S; Bielicki J; Walker S; Heath PT; Sharland M
  • Conference publication: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2020;101:442
    Pham N; Le N; Olson L; Larsson M; Tran DM
  • Preprint: ARXIV. 2020
    Hochwarter S; Cuong DD; Chuc NTK; Larsson M
  • Preprint: SSRN ELECTRONIC JOURNAL. 2019
    Tran DM; Larsson M; Olson L; Hoang NT; Le NK; Khu DT; Nguyen HD; Vu TV; Trinh TH; Le TQ; Phan PT; Nguyen BG; Pham NH; H. B; Nguyen TV; Nguyen PT; Le ND; Huynh TM; Thu LT; Thanh TC; Berglund B; Nilsson LE; Bornefall E; Song LH; Hanberger H
  • Letter: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2018;73(4):1100-1102
    Berglund B; Ngoc TBH; Tarnberg M; Ngai KL; Welander J; Nilsson M; Dung TKK; Nilsson LE; Olson L; Hai TL; Larsson M; Hanberger H
  • Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2017;27:ckx187.201
    Riggi E; Le NK; Marrone G; Izurieta RO; Larsson M; Cuong DD
  • Letter: JOURNAL OF MEDICAL MICROBIOLOGY. 2013;62(Pt 11):1772-1773
    Quaglia A; Karlsson M; Larsson M; Taylor WR; Diep NTN; Trinh DT; Trung NV; Van Kinh N; Wertheim HFL
  • Letter: JOURNAL OF INFECTION. 2013;66(5):461-464
    Ta TDN; Thomas S; Larsson M; Horby P; Nguyen ND; Vu QD; Nguyen VT; Nguyen HH; van Doorn HR; Nguyen VK; Wertheim HFL
  • Editorial comment: PLOS MEDICINE. 2013;10(5):e1001429
    Wertheim HFL; Chandna A; Vu PD; Pham CV; Nguyen PDT; Lam YM; Nguyen CVV; Larsson M; Rydell U; Nilsson LE; Farrar J; Nguyen KV; Hanberger H
  • Thesis / dissertation: 2003
    Larsson, Mattias
  • Corrigendum: JOURNAL OF CLINICAL EPIDEMIOLOGY. 2003;56(6):604
    Chuc NT; Larsson M; Do NT; Diwan VK; Tomson GB; Falkenberg T

Grants

  • Swedish Research Council
    1 January 2022 - 31 December 2024
  • Swedish Research Council
    1 April 2018 - 31 December 2020
  • Swedish Research Council
    1 January 2015 - 31 December 2018
  • Swedish Research Council
    1 January 2012 - 31 December 2014
  • Medical Research Council
    31 July 2011 - 30 March 2017
  • Swedish Research Council
    1 January 2011 - 31 December 2013
  • Swedish Research Council
    1 January 2010 - 31 December 2012

Employments

  • Researcher, Department of Global Public Health, ̽ѡ, 2015-

Degrees and Education

  • Docent, ̽ѡ, 2015
  • Doctor Of Philosophy, Department of Global Public Health, ̽ѡ, 2003

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