̽»¨¾«Ñ¡

Mattias Carlström

Mattias Carlström

Professor
Telephone: +46852486850
Visiting address: Solnavägen 9, Biomedicum B5, 17165 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa Reaktiva syreradikaler och kväveoxid i njur- och hjärtkärlforskning, 171 77 Stockholm
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About me

  • Mattias Carlström is Professor of Cardiorenal Physiology and group leader for Reactive oxygen species and nitric oxide signaling in Reno-Cardio-Metabolic Regulation at the Department of Physiology and Pharmacology.

    Education
    Professor of Cardiorenal Physiology, ̽»¨¾«Ñ¡, Dept. of Physiology & Pharmacology (2022-)
    Associate Professor of Physiology, ̽»¨¾«Ñ¡, Dept. of Physiology & Pharmacology (2015-2022)
    Adjunct Assistant Professor, Georgetown University, Washington DC, Dept. of Medicine, Div of Nephrology & Hypertension (2011-)
    Postdoc: Georgetown University, Div. of Nephrology & Hypertension, DC, USA, (2009-2011)
    Postdoc: ̽»¨¾«Ñ¡, Dept. of Physiology & Pharmacology (2008-2009)
    PhD Medicine, Dept. of Medical Cell Biology, Uppsala University (2008)
    Degree of Master of Science in Pharmacy, Uppsala University (2003)
    Degree of Master of Science in Pharmaceutical Science, Uppsala University (2002)


    Academic honours, awards and prizes
    2022: SRP Diabetes - The Rolf Luft Grant for Instrumentation

    2019: Novo Nordisk Foundation (5 years) – Ascending Investigator Grant - Endocrinology & Metabolism

    2019: Distinguished Professor, Weifang Medical University, China

    2019. Senior Research Award (2 years), ̽»¨¾«Ñ¡

    2017: Heart and Lung Foundation (3 years) – Prince Daniel’s Award, Sweden

    2015: Fo-Ass Research Grant (4 years), ̽»¨¾«Ñ¡

    2012: Lewis T. Preston Research Achievement Award, Georgetown University, USA

    2012: Top Young Investigator Award, ASN, Kidney Week, Philadelphia, USA

    2011: Lewis T. Preston Research Achievement Award, Georgetown University, USA

    2011: Fellows Forum Presentation Winner, National Kidney Foundation, NIH, USA

    2010: Young Investigator Award – Society Free Radical Biology Meeting, Orlando, USA

    2010: Fellows Forum Presentation Winner, National Kidney Foundation, NIH, USA

    2009: Young Investigator Award – 3rd Int. Meeting on the Role of Nitrite in Physiology, Pathophysiology, and Therapeutics, Sweden

    2007: Young Investigator Award - Scand. Physiol. Society Annual Meeting, Norway

Research

  • Emerging evidence suggests that renal oxidative stress and nitric oxide (NO) deficiency is linked to cardiovascular disease and diabetic complications. Mechanisms are not clear, but exaggerated NADPH oxidase- and mitochondria-derived superoxide production and NO deficiency may impair vascular function and lead to impairment of renal autoregulation. Using a translational design, our projects aim to characterize the mechanisms for superoxide and NO formation, interaction and influence on renal, cardiovascular and metabolic functions in health and disease. Novel dietary and pharmacological therapeutic strategies, focusing on dampening of vascular oxidative stress, are investigated and characterized in experimental disease models and in patients with reno-cardio-metabolic disorders, including chronic kidney disease, hypertension and type 2 diabetes.

Teaching

  • -Kidney physiology, pathophysiology and pharmacology (teaching at various courses and programs)

    -Cardiovascular physiology, pathophysiology and pharmacology (teaching at various courses and programs)

Articles

  • Article: BRITISH JOURNAL OF PHARMACOLOGY. 2025;182(2):417-431
    Collado A; Jiao T; Kontidou E; Carvalho LRRA; Chernogubova E; Yang J; Zaccagnini G; Zhao A; Tengbom J; Zheng X; Rethi B; Alvarsson M; Catrina S-B; Mahdi A; Carlstroem M; Martelli F; Pernow J; Zhou Z
  • Journal article: LIFE SCIENCES. 2024;359:123257
    Fernandes-Costa F; da Silva RTG; de Almeida AJPO; de Medeiros IA; Tafuri LSDA; dos Santos GJ; Carlstrom M; Cruz JC
  • Article: NUTRIENTS. 2024;16(23):4105
    Carvalho LRRA; Tyden M; Shimari M; Zhuge Z; Schiffer TA; Monteiro MMDO; Lundberg JO; Weitzberg E; Andersson DC; Fellstroem B; Carlstrom M
  • Article: LAB ANIMAL. 2024;53(11):336-346
    Carvalho LRRA; Shimari M; Boeder AM; Zhuge Z; Cai M; Leijding C; Gastaldello S; Kleschyov AL; Schiffer TA; Guimaraes DD; Picozzi G; Lund LH; Fellstrom B; Weitzberg E; Lundberg JO; Hagberg CE; Pironti G; Andersson DC; Carlstrom M
  • Journal article: EUROPEAN HEART JOURNAL. 2024;45:ehae666.3757
    Pironti G; Hage C; Carlstrom M; Champeroux P; Stahlberg M; Stromberg P; Lovati E; Andersson DC; Lund LH
  • Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024;35(10):10.1681/asn.20247ztatrk0
    Fellstrom BC; Carvalho L; Tyden M; Monteiro M; Andersson DC; Schiffer TA; Carlstrom M
  • Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39:gfae069-0503-1131
    Carvalho L; Tyden M; Fellstrom B; Monteiro MMDO; Andersson D; Schiffer T; Carlstrom M
  • Journal article: ANTIOXIDANTS. 2024;13(4):489
    Schiffer TA; Carvalho LRRA; Guimaraes D; Boeder A; Wikström P; Carlström M
  • Article: MOLECULAR METABOLISM. 2024;82:101912
    Ducommun S; Jannig PR; Cervenka I; Murgia M; Mittenbuhler MJ; Chernogubova E; Dias JM; Jude B; Correia JC; Van Vranken JG; Ocana-Santero G; Porsmyr-Palmertz M; Haworth SM; Martinez-Redondo V; Liu Z; Carlstrom M; Mann M; Lanner JT; Teixeira AI; Maegdefessel L; Spiegelman BM; Ruas JL
  • Article: SCIENTIFIC REPORTS. 2024;14(1):4025
    Carvalho LRRA; Boeder AM; Shimari M; Kleschyov AL; Esberg A; Johansson I; Weitzberg E; Lundberg JO; Carlstrom M
  • Article: REDOX BIOLOGY. 2024;69:102984
    Carlstrom M; Carvalho LRRA; Guimaraes D; Boeder A; Schiffer TA
  • Article: ANTIOXIDANTS. 2024;13(4):489
    Schiffer TA; Carvalho LRRA; Guimaraes D; Boeder A; Wikstrom P; Carlstrom M
  • Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3099
    Yang JN; Sundqvist M; Zheng X; Jiao T; Collado A; Mahdi A; Tengbom J; Mergia E; Zhou Z; Carlstrom M; Akaike T; Cortese-Krott M; Weitzberg E; Lundberg JO; Pernow J
  • Article: PHYSIOLOGICAL REPORTS. 2023;11(22):e15886
    Krmar RT; Franzen S; Karlsson L; Strandberg H; Tornroth-Horsefield S; Andresen JK; Jensen BL; Carlstrom M; Frithiof R
  • Article: PEDIATRIC RESEARCH. 2023;94(4):1373-1379
    Roberts DN; Vallen P; Cronhjort M; Alfven T; Sandblom G; Tonroth-Horsefield S; Jensen BL; Lonnqvist P-A; Frithiof R; Carlstrom M; Krmar RT
  • Article: NATURE CHEMICAL BIOLOGY. 2023;19(10):1267-1275
    Kleschyov AL; Zhuge Z; Schiffer TA; Guimaraes DD; Zhang G; Montenegro MF; Tesse A; Weitzberg E; Carlstrom M; Lundberg JO
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693
    Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
  • Article: JOURNAL OF FUNCTIONAL FOODS. 2023;104:105526
    Fernandes-Costa F; da Silva RTG; Flor AFDL; Brandao MCR; Athayde-Filho PF; Franca-Falcao MDS; Braga VDA; dos Santos GJ; Carlstrom M; Cruz JDC
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14):e2212476120
    Tarnawski L; Shavva VS; Kort EJ; Zhuge Z; Nilsson I; Gallina AL; Martinez-Enguita D; Sahlgren BH; Weiland M; Caravaca AS; Schmidt S; Chen P; Abbas K; Wang F-H; Ahmed O; Eberhardson M; Farnert A; Weitzberg E; Gustafsson M; Kehr J; Malin SG; Hult H; Carlstrom M; Jovinge S; Olofsson PS
  • Article: REDOX BIOLOGY. 2023;60:102612
    Zhuge Z; Haworth SM; Nihlen C; Carvalho LRRA; Heuser SK; Kleschyov AL; Nasiell J; Cortese-Krott MM; Weitzberg E; Lundberg JO; Carlstroem M
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All other publications

  • Review: PHARMACOLOGICAL REVIEWS. 2024;76(6):1038-1062
    Carlstroeurom M; Weitzberg E; Lundberg JO
  • Review: WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY. 2024;40(6):190
    Boeder AM; Spiller F; Carlstrom M; Izidio GS
  • Conference publication: 2024
    Lundberg J; Kleschyov AL; Zhuge Z; Schiffer TA; Guimarães DD; Zhang G; Montenegro MF; Tesse A; Weitzberg E; Carlström M
  • Corrigendum: PEDIATRIC RESEARCH. 2024;95(5):1382
    Roberts DN; Vallen P; Cronhjort M; Alfven T; Sandblom G; Tornroth-Horsefield S; Jensen BL; Lonnqvist P-A; Frithiof R; Carlstrom M; Krmar RT
  • Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39:I821-I822
    Carvalho L; Tyden M; Fellstrom B; Monteiro MMDO; Andersson D; Schiffer T; Carlstrom M
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2024;76:5415-5417
    Leijding C; Kaewin S; Andreasson K; Schiffer T; Galindo-Feria A; Horuluoglu B; Carlstrom M; Gastaldello S; Alexanderson H; Lundberg I; Andersson D
  • Conference publication: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2024;42(2):491-492
    Leijding C; Gastaldello S; Andreasson KM; Schiffer T; Kaewin S; Yamada T; Carlstrom M; Lundberg IE; Alexanderson H; Andersson DC
  • Preprint: RESEARCH SQUARE. 2023
    Carlstrom M; Carvalho L; Boeder A; Shimari M; Kleshchev A; Esberg A; Johansson I; Weitzberg E; Lundberg J
  • Preprint: RESEARCH SQUARE. 2023
    Kleschyov A; Zhuge Z; Schiffer T; Guimarães D; Zhang G; Montenegro M; Tesse A; Weitzberg E; Carlström M; Lundberg J
  • Book chapter: THE ROLE OF NITRIC OXIDE IN TYPE 2 DIABETES. 2022;p. 107-127
    Bahadoran Z; Mirmiran P; Carlström M; Ghasemi A
  • Book chapter: THE ROLE OF NITRIC OXIDE IN TYPE 2 DIABETES. 2022;p. 67-86
    Bahadoran Z; Carlström M; Mirmiran P; Ghasemi A
  • Book chapter: THE ROLE OF NITRIC OXIDE IN TYPE 2 DIABETES. 2022;p. 39-66
    Bahadoran Z; Carlström M; Mirmiran P; Ghasemi A
  • Conference publication: ACTA PHYSIOLOGICA. 2022;236:137
    Landberg C; Gastaldello S; Andreasson K; Schiffer T; Carlstrom M; Lundberg IE; Alexanderson H; Andersson DC
  • Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S25
    Collado A; Jiao T; Zaccagnini G; Yang J; Carlstrom M; Martelli F; Pernow J; Zhou Z
  • Review: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2021;116:38-46
    Bahadoran Z; Mirmiran P; Carlstrom M; Ghasemi A
  • Review: NATURE REVIEWS NEPHROLOGY. 2021;17(9):575-590
    Carlstrom M
  • Preprint: BIORXIV. 2021
    Tarnawski L; Gallina A; Kort E; Shavva V; Zhuge Z; Martínez-Enguita D; Weiland M; Caravaca A; Schmidt S; Wang F; Färnert A; Weitzberg E; Gustafsson M; Eberhardson M; Hult H; Kehr J; Malin S; Carlström M; Jovinge S; Olofsson P
  • Review: JOURNAL OF APPLIED PHYSIOLOGY. 2021;130(4):914-922
    Ferguson SK; Woessner MN; Holmes MJ; Belbis MD; Carlstrom M; Weitzberg E; Allen JD; Hirai DM
  • Conference publication: EUROPEAN JOURNAL OF HEART FAILURE. 2021;23:31
    Pironti G; Gastaldello S; Rassier D; Carlstrom M; Lund LH; Westerblad H; Yamada T; Andersson D
  • Other: ACTA PHYSIOLOGICA. 2020;230(4):1-2
    Schnermann J; Carlstrom M; Hansell P; Palm F; Phillipson M; Sallstrom J
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Grants

  • Swedish Research Council
    1 January 2025 - 31 December 2028
  • Swedish Heart-Lung Foundation
    1 January 2021 - 31 December 2021
  • Swedish Research Council
    1 January 2021 - 31 December 2024
  • Coordenação de Aperfeicoamento de Pessoal de Nível Superior
    2 April 2019
  • Swedish Heart-Lung Foundation
    1 January 2019 - 31 December 2021
  • Swedish Research Council
    1 January 2017 - 31 December 2020
  • Swedish Research Council
    1 January 2012 - 31 December 2014
  • Deutsche Forschungsgemeinschaft
    1 January 2011 - 31 December 2021
  • Swedish Research Council
    1 January 2011 - 31 December 2013
  • Swedish Research Council
    1 January 2009 - 31 December 2010

Employments

  • Professor, Department of Physiology and Pharmacology, ̽»¨¾«Ñ¡, 2022-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2015

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