̽»¨¾«Ñ¡

Kristian Dreij

Kristian Dreij

Principal Researcher | Docent
Visiting address: Nobels väg 13, 17177 Stockholm
Postal address: C6 Institutet för miljömedicin, C6 Biokemisk toxikologi Dreij, 171 77 Stockholm

About me

  • Head of Unit and Research Group Leader at the Institute of Environmental Medicine, ̽»¨¾«Ñ¡.


    I received my Ph.D. in Toxicology in 2005 from the laboratory of Prof. Jernström at KI. My research focused on the protective role of cellular metabolism and DNA repair against carcinogenic environmental contaminants. Following my Ph.D., I worked as a postdoctoral fellow in the laboratory of Prof. Scicchitano at the Department of Biology, New York University, where our project focused on the effects of chemical interactions with DNA and how cells deal with the resulting damage.


    My current research aims to shift the focus from studying the genotoxic effects of single chemicals to understanding the effects of complex mixtures found in our environment. We investigate genotoxicity in exposed populations and on human cells using environmental samples. This allows us to identify mechanisms of mixture toxicity and improve health risk assessment of environmental pollution. Current projects focus on urban and rural air pollution, and past projects have investigated genotoxic mixture effects in the context of soil contamination, indoor air quality in pre-schools, and occupational exposure to pesticides. We also study the effects of genotoxic chemicals and mixtures on transcription and replication fidelity by analyzing RNA and DNA mutagenesis.


    In 2016, I was appointed Associate Professor/Docent in Toxicology, and I am also Deputy Program Director of the global at ̽»¨¾«Ñ¡.

Selected publications

  • Article: ENVIRONMENT INTERNATIONAL. 2024;190:108942
    Galvao MFDO; Scaramboni C; Endirlik BU; Silva AV; Oberg M; Pozza SA; Watanabe T; Rodrigues PCDO; Vasconcellos PDC; Sadiktsis I; Dreij K
  • Article: ENVIRONMENTAL POLLUTION. 2023;316(Pt 1):120510
    Endirlik BU; Wincent E; Dreij K
  • Article: ENVIRONMENT INTERNATIONAL. 2022;166:107345
    Galvao MFDO; Sadiktsis I; Pedro TM; Dreij K
  • Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2021;129(6):67008
    Ali I; Dreij K; Baker S; Hogberg J; Korhonen A; Stenius U
  • Article: ENVIRONMENT INTERNATIONAL. 2020;143:105913
    Cunha V; Vogs C; Bihanic FL; Dreij K
  • Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2019;695:133942
    Cuenca JB; Tirado N; Barral J; Ali I; Levi M; Stenius U; Berglund M; Dreij K
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(18):4731-4736
    Ezerskyte M; Paredes JA; Malvezzi S; Burns JA; Margison GP; Olsson M; Scicchitano DA; Dreij K
  • Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2017;51(15):8805-8814
    Dreij K; Mattsson A; Jarvis IWH; Lim H; Hurkmans J; Gustafsson J; Bergvall C; Westerholm R; Johansson C; Stenius U
  • Article: NUCLEIC ACIDS RESEARCH. 2017;45(11):6520-6529
    Paredes JA; Ezerskyte M; Bottai M; Dreij K
  • Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2015;49(6):3869-3877
    Wincent E; Jonsson ME; Bottai M; Lundstedt S; Dreij K
  • Review: TOXICOLOGY. 2014;321:27-39
    Jarvis IWH; Dreij K; Mattsson Å; Jernström B; Stenius U

Articles

  • Article: ENVIRONMENTAL POLLUTION. 2024;363(Pt 2):125189
    Martins C; Carvalho LM; Cabral IM; Saude L; Dreij K; Costa PM
  • Article: ATMOSPHERIC RESEARCH. 2024;305:107423
    Scaramboni C; Farias CN; Vasconcellos PDC; Levi M; Sadiktsis I; Pozza SA; Umbuzeiro GDA; Watanabe T; Rodrigues PCDO; Grandis A; Buckeridge MS; Campos MLAM; Kippler M; Dreij K; Galva MFDO
  • Article: ENVIRONMENT INTERNATIONAL. 2024;189:108798
    Igra AM; Trask M; Rahman SM; Dreij K; Lindh C; Krais AM; Persson L-A; Rahman A; Kippler M
  • Article: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY. 2024;108:104453
    Martins C; Galvao MFDO; Costa PM; Dreij K
  • Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2024;21(3):305
    Barrón Cuenca J; Dreij K; Tirado N
  • Article: TOXICOLOGY IN VITRO. 2023;91:105628
    Scaramboni C; Campos MLAM; Dorta DJ; Oliveira DPD; Medeiros SRBD; Galva MFDO; Dreij K
  • Article: CHEMOSPHERE. 2023;332:138862
    Sadiktsis I; Galvao MDO; Mustafa M; Toublanc M; Endirlik BU; Silvergren S; Johansson C; Dreij K
  • Article: ENVIRONMENTAL RESEARCH. 2023;227:115787
    Rahman SM; Igra AM; Essig JY; Ekstrom E-C; Dreij K; Trask M; Lindh C; El Arifeen S; Rahman A; Krais AM; Kippler M
  • Article: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY. 2022;96:103999
    Endirlik BU; Bakir E; Okcesiz A; Guler A; Hamurcu Z; Eken A; Dreij K; Gurbay A
  • Article: FOOD CONTROL. 2022;132:108528
    Ekner H; Dreij K; Sadiktsis I
  • Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 2022;63(1):4-17
    Barron Cuenca J; de Oliveira Galvao MF; Unlu Endirlik B; Tirado N; Dreij K
  • Article: AUTOPHAGY. 2021;17(5):1259-1277
    Gonzalez-Rodriguez P; Cheray M; Fullgrabe J; Salli M; Engskog-Vlachos P; Keane L; Cunha V; Lupa A; Li W; Ma Q; Dreij K; Rosenfeld MG; Joseph B
  • Article: SCIENCE OF THE TOTAL ENVIRONMENT. 2021;755(Pt 1):142709
    Lim H; Sadiktsis I; Galvao MFDO; Westerholm R; Dreij K
  • Article: VASCULAR MEDICINE. 2021;26(1):3-10
    Ziegler L; Lundqvist J; Dreij K; Wallen H; de Faire U; Paulsson-Berne G; Hedin U; Matic L; Gigante B
  • Article: SCIENTIFIC REPORTS. 2020;10(1):13513
    Liang S; Ezerskyte M; Wang J; Pelechano V; Dreij K
  • Article: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2020;30(4):730-742
    Barron Cuenca J; Tirado N; Vikstrom M; Lindh CH; Stenius U; Leander K; Berglund M; Dreij K
  • Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 2020;61(5):560-573
    Maselli BS; Cunha V; Lim H; Bergvall C; Westerholm R; Dreij K; Watanabe T; Cardoso AA; Pozza SA; Umbuzeiro GA; Kummrow F
  • Article: ENVIRONMENTAL RESEARCH. 2020;182:108989
    Dreij K; Lundin L; Le Bihanic F; Lundstedt S
  • Article: ENVIRONMENTAL POLLUTION. 2020;256:113381
    Galvao MFDO; Sadiktsis I; Batistuzzo de Medeiros SR; Dreij K
  • Journal article: ENVIRONMENTAL EPIDEMIOLOGY. 2019;3(Supplement 1):22-23
    J B; N T; J B; C L; U S; M B; K D
  • Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 2019;60(7):607-616
    Maselli BS; Giron MCG; Lim H; Bergvall C; Westerholm R; Dreij K; Watanabe T; Cardoso AA; Umbuzeiro GA; Kummrow F
  • Article: CARCINOGENESIS. 2019;40(4):580-591
    Zheng H; Jarvis IWH; Bottai M; Dreij K; Stenius U
  • Article: ENVIRONMENTAL POLLUTION. 2019;246:678-687
    McCarrick S; Cunha V; Zapletal O; Vondracek J; Dreij K
  • Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy565.p2625
    Ziegler L; Lundqvist J; Perisic L; Gajulapuri A; Dreij K; Frumento P; Paulsson-Berne G; Wallen H; De Faire U; Hedin U; Gigante B
  • Article: REDOX BIOLOGY. 2018;17:171-179
    Brautigam L; Zhang J; Dreij K; Spahiu L; Holmgren A; Abe H; Tew KD; Townsend DM; Kelner MJ; Morgenstern R; Johansson K
  • Journal article: FRONTIERS IN MARINE SCIENCE. 2018;5
    Martins C; Cunha V; Dreij K; Costa P
  • Article: ANTIOXIDANTS & REDOX SIGNALING. 2017;26(6):229-246
    Johansson K; Cebula M; Rengby O; Dreij K; Carlstrom KE; Sigmundsson K; Piehl F; Arner ESJ
  • Article: MUTAGENESIS. 2017;32(1):127-137
    Di Bucchianico S; Cappellini F; Le Bihanic F; Zhang Y; Dreij K; Karlsson HL
  • Article: MUTAGENESIS. 2016;31(6):643-653
    Le Bihanic F; Di Bucchianico S; Karlsson HL; Dreij K
  • Article: TOXICOLOGY RESEARCH. 2016;5(3):788-799
    Wincent E; Le Bihanic F; Dreij K
  • Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2015;49(5):3101-3109
    Lim H; Mattsson Ã…; Jarvis IWH; Bergvall C; Bottai M; Morales DA; Kummrow F; Umbuzeiro GA; Stenius U; Westerholm R; Dreij K
  • Article: TOXICOLOGY LETTERS. 2014;229(1):25-32
    Jarvis IWH; Bergvall C; Morales DA; Kummrow F; Umbuzeiro GA; Westerholm R; Stenius U; Dreij K
  • Article: JOURNAL OF CHROMATOGRAPHY A. 2014;1355:100-106
    Lim H; Bergvall C; Jarvis I; Mattsson Ã…; Dreij K; Stenius U; Westerholm R
  • Article: ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. 2014;55(6):510-517
    Umbuzeiro GA; Kummrow F; Morales DA; Alves DKM; Lim H; Jarvis IWH; Bergvall C; Westerholm R; Stenius U; Dreij K
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(50):20057-20062
    Brautigam L; Jensen LDE; Poschmann G; Nystrom S; Bannenberg S; Dreij K; Lepka K; Prozorovski T; Montano SJ; Aktas O; Uhlen P; Stuehler K; Cao Y; Holmgren A; Berndt C
  • Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2013;266(3):408-418
    Jarvis IWH; Bergvall C; Bottai M; Westerholm R; Stenius U; Dreij K
  • Article: CHEMICAL RESEARCH IN TOXICOLOGY. 2012;25(4):862-872
    Niziolek-Kierecka M; Dreij K; Lundstedt S; Stenius U
  • Article: PLOS ONE. 2012;7(8):e43209
    Kadekar S; Silins I; Korhonen A; Dreij K; Al-Anati L; Hogberg J; Stenius U
  • Article: DNA REPAIR. 2011;10(8):877-886
    Lagerqvist A; Hakansson D; Lundin C; Prochazka G; Dreij K; Segerback D; Jernstrom B; Tornqvist M; Franke H; Seidel A; Erixon K; Jenssen D
  • Article: PLOS ONE. 2011;6(8):e23128
    Dreij K; Chaudhry QA; Jernstrom B; Morgenstern R; Hanke M
  • Article: NUCLEIC ACIDS RESEARCH. 2010;38(22):8178-8187
    Burns JA; Dreij K; Cartularo L; Scicchitano DA
  • Article: CARCINOGENESIS. 2010;31(6):1149-1157
    Dreij K; Rhrissorrakrai K; Gunsalus KC; Geacintov NE; Scicchitano DA
  • Article: DNA REPAIR. 2008;7(8):1202-1212
    Lagerqvist A; Hakansson D; Prochazka G; Lundin C; Dreij K; Segerback D; Jernstrom B; Tornqvist M; Seidel A; Erixon K; Jenssen D
  • Article: CHEMICAL RESEARCH IN TOXICOLOGY. 2003;16(5):590-597
    Cho KB; Dreij K; Jernström B; Gräslund A
  • Article: CHEMICAL RESEARCH IN TOXICOLOGY. 2002;15(2):170-179
    Sundberg K; Dreij K; Seidel A; Jernström B
  • Show more

All other publications

  • Corrigendum: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2022;32(5):782
    Barron Cuenca J; Tirado N; Vikstrom M; Lindh CH; Stenius U; Leander K; Berglund M; Dreij K
  • Corrigendum: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2020;30(4):768
    Cuenca JB; Tirado N; Vikstrom M; Lindh CH; Stenius U; Leander K; Berglund M; Dreij K
  • Review: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2019;16(23):E4718-4718
    Martins C; Dreij K; Costa PM
  • Published conference paper: JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS. 2014;262:244-260
    Chaudhry QA; Hanke M; Morgenstern R; Dreij K
  • Meeting abstract: TOXICOLOGY LETTERS. 2012;211:S60-S61
    Dreij K; Chaudhry QA; Zhang J; Sundberg K; Jernstrom B; Hanke M; Morgenstern R
  • Meeting abstract: TOXICOLOGY LETTERS. 2012;211:S68-S69
    Dreij K; Malvezzi S; Burns J; Scicchitano DA; Stenius U
  • Meeting abstract: TOXICOLOGY LETTERS. 2012;211:S54-S55
    Kadekar S; Silins I; Korhonen A; Dreij K; Al-Anati L; Hogberg J; Stenius U
  • Meeting abstract: TOXICOLOGY LETTERS. 2012;211:S35
    Dreij K; Jarvis I; Bergvall C; Lundstedt S; Roger W; Stenius U
  • Book chapter: THE CHEMICAL BIOLOGY OF DNA DAMAGE. 2010;p. 399-437
    Dreij K; Burns JA; Dimitri A; Nirenstein L; Noujnykh T; Scicchitano DA
  • Doctoral thesis: 2005
    Dreij K
  • Published conference paper: CHEMICAL RESEARCH IN TOXICOLOGY. 2005;18(4):655-664
    Dreij K; Seidel A; Jernström B
  • Published conference paper: POLYCYCLIC AROMATIC COMPOUNDS. 2004;24(4-5):549-566
    Dreij K; Bajak E; Sundberg K; Cotgreave I; Jernström B; Seidel A; Gusnanto A
  • Published conference paper: CHEMICAL RESEARCH IN TOXICOLOGY. 2002;15(6):825-831
    Dreij K; Sundberg K; Johansson AS; Nordling E; Seidel A; Persson B; Mannervik B; Jernström B
  • Published conference paper: POLYCYCLIC AROMATIC COMPOUNDS. 2002;22(3-4):947-953
    Sundberg K; Dreij K; Jernström B; Seidel A
  • Published conference paper: POLYCYCLIC AROMATIC COMPOUNDS. 2002;22(3-4):823-829
    Dreij K; Sundberg K; Jernström B; Johansson AS; Mannervik B; Seidel A
  • Published conference paper: CHEMICO-BIOLOGICAL INTERACTIONS. 2001;133(1-3):91-94
    Sundberg K; Dreij K; Berntsen S; Seidel A; Jernström B

Grants

  • Swedish Research Council
    1 January 2023 - 31 December 2026
  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2023 - 31 December 2026
  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2022 - 31 December 2025
  • Swedish Research Council
    1 January 2020 - 31 December 2021
  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2020 - 31 December 2022
  • Swedish Foundation for International Cooperation in Research and Higher Education
    1 January 2020 - 1 January 2023
  • Swedish Research Council
    1 January 2018 - 31 December 2021
  • Swedish Research Council
    1 January 2017 - 31 December 2019
  • Measurement of PAHs in indoor and outdoor air at preschools in Stockholm.
    Stockholm Regional Council
    1 February 2016 - 31 December 2018
  • Swedish Research Council
    1 January 2013 - 31 December 2016
  • Swedish International Development Cooperation Agency
    1 January 2013 - 1 January 2021
  • Swedish Research Council
    1 January 2012 - 31 December 2014
  • FP7 Marie Curie International Reintegration Grants
    1 May 2010 - 1 May 2012

Employments

  • Principal Researcher, Institute of Environmental Medicine, ̽»¨¾«Ñ¡, 2022-
  • Researcher, Institute of Environmental Medicine, ̽»¨¾«Ñ¡, 2015-2021

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2016
  • Doctor Of Philosophy, Institute of Environmental Medicine, ̽»¨¾«Ñ¡, 2005

Leadership and responsibility assignments

  • Head of unit, Institute of Environmental Medicine, ̽»¨¾«Ñ¡, 2022-
  • Deputy Programme Director, Master's Programme in Toxicology, Institute of Environmental Medicine, ̽»¨¾«Ñ¡, 2012-

Supervision

  • Jessika Barrón Cuenca, Genotoxic effects among Bolivian farmers exposed to mixtures of pesticides : population and in vitro based studies,
  • Monika Ezerskyte, The impact of transcriptional mutagenesis on cellular homeostasis,
  • Sandeep Kadekar, Gender differences in chemical carcinogenesis,
  • Carla Martins, Carcinogenic toxicants and emerging pollutants. A comprehensive case-study on toxicant interactions in vivo and in vitro: from Molecular Toxicology to Environmental Risk Assessment,

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