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Katalin Dobra

Katalin Dobra

Professor/Senior Physician
Visiting address: BioClinicum Visionsgatan 4, 17176 SOLNA
Postal address: K7 Onkologi-Patologi, K7 Forskning Dobra, 171 77 Stockholm

About me

  • I am Senior Physician and Professor of Clinical Pathology at the Department of Oncology-Pathology.

Research

  • My research is about cancer of the lungs and pleurae – diseases that generally have a poor prognosis. In my research group, we study both primary cancer and metastases and our long-term goal is to help cancer patients obtain earlier and more accurate diagnoses and prognoses so that they can be given personalised treatment. The research spans the mapping of fundamental mechanisms of tumour growth to the development of new analytical methods and biomarkers.

    I have a particular interest in the protein syndecan 1, which, in being involved in cell division, is relevant to tumour growth. The protein is anchored to the cell membrane, but we have made the surprising discovery that it is also found in the nucleus. We have also shown that soluble syndecan 1 in bodily fluids can be used as a biomarker for identifying aggressive tumours requiring more extensive treatment.

Articles

  • Article: CANCERS. 2024;17(1):81
    Rosier M; Krstulovic A; Kim HR; Kaur N; Enakireru EM; Symmes D; Dobra K; Chen R; Evans CA; Gad AKB
  • Article: CYTOPATHOLOGY. 2023;34(5):456-465
    Mansour MSI; Huseinzade A; Seidal T; Hejny K; Maty A; Taheri-Eilagh F; Mager U; Dejmek A; Dobra K; Brunnstrom H
  • Article: HAEMATOLOGICA. 2023;108(9):2422-2434
    Hagey DW; Kvedaraite E; Akber M; Goergens A; Javadi J; Greenwood TVB; Bjorklund C; Akefeldt SO; Hannegard-Hamrin T; Arnell H; Dobra K; Herold N; Svensson M; El Andaloussi S; Henter J-I; Lourda M
  • Article: CANCER MEDICINE. 2023;12(5):5334-5340
    Hjerpe A; Demir E; Abd-Own S; Dobra K
  • Journal article: REVISTA CHILENA DE LITERATURA. 2023;(108):2422-2434
    Hagey DW; Kvedaraite E; Akber M; Gorgens A; Javadi J; Greenwood TVB; Bjorklund C; Akefeldt SO; Hannegard-Hamrin T; Arnell H; Dobra K; Herold N; Svensson M; El Andaloussi S; Henter J-I; Lourda M
  • Article: JOURNAL OF CLINICAL PATHOLOGY. 2022;75(5):302-309
    Lindquist KE; Ciornei C; Westbom-Fremer S; Gudinaviciene I; Ehinger A; Mylona N; Urdar R; Lianou M; Svensson F; Seidal T; Haglund F; Dobra K; Bendek M; Bardoczi E; Szablewska A; Witkowski M; Ramnefjell M; De las Casas LE; Gulyas M; Hegedus A; Micke P; Brunnstrom H
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(9):4517
    Mansour MSI; Malmros K; Mager U; Lindquist KE; Hejny K; Holmgren B; Seidal T; Dejmek A; Dobra K; Planck M; Brunnstrom H
  • Article: BIOMOLECULES. 2021;11(11):1721
    Ericson Lindquist K; Gudinaviciene I; Mylona N; Urdar R; Lianou M; Darai-Ramqvist E; Haglund F; Bendek M; Bardoczi E; Dobra K; Brunnstroem H
  • Article: BIOMOLECULES. 2021;11(11):1606
    Javadi J; Goergens A; Vanky H; Gupta D; Hjerpe A; EL-Andaloussi S; Hagey D; Dobra K
  • Article: BIOLOGY-BASEL. 2021;10(6):521
    Kumar-Singh A; Parniewska MM; Giotopoulou N; Javadi J; Sun W; Szatmari T; Dobra K; Hjerpe A; Fuxe J
  • Article: PATHOLOGY. 2021;53(4):446-453
    Klebe S; Nakatani Y; Dobra K; Butnor KJ; Roden AC; Nicholson AG; Marchevsky AM; Husain AN; Segal A; Walts AE; Weynand B; Michael CW; Dacic S; Godbolt D; Attanoos R; Santoni-Rugiu E; Galateau-Salle F; Hiroshima K; Moreira AL; Burn J; Nabeshima K; Gibbs AR; Churg A; Litzky LA; Brcic L; Tsao MS; Mino-Kenudson M; Rorvig SB; Tazelaar HD; Krausz T; Zhang YZ; Chirieac LR; Beasley MB; Hjerpe A
  • Article: CANCER CYTOPATHOLOGY. 2021;129(6):468-478
    Mansour MSI; Seidal T; Mager U; Dobra K; Brunnstrom H; Dejmek A
  • Article: DIAGNOSTIC CYTOPATHOLOGY. 2021;49(5):606-614
    Abd Own S; Hoijer J; Hillerdahl G; Dobra K; Hjerpe A
  • Article: CANCERS. 2021;13(4):685
    Keller M; Reis K; Hjerpe A; Dobra K; Aspenstrom P
  • Article: CANCERS. 2021;13(4):655
    Javadi J; Heidari-Hamedani G; Schmalzl A; Szatmari T; Metintas M; Aspenstrom P; Hjerpe A; Dobra K
  • Article: ONCOTARGET. 2020;11(50):4637-4647
    Reis K; Arbiser JL; Hjerpe A; Dobra K; Aspenström P
  • Article: BIOMOLECULES. 2020;10(8):E1113-1113
    Javadi J; Dobra K; Hjerpe A
  • Article: BIOMOLECULES. 2020;10(7):E1034-1034
    Kumar-Singh A; Shrinet J; Parniewska MM; Fuxe J; Dobra K; Hjerpe A
  • Article: LIVER INTERNATIONAL. 2019;39(2):382-388
    von Seth E; Ouchterlony H; Dobra K; Hjerpe A; Arnelo U; Haas S; Bergquist A
  • Article: ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE. 2018;142(8):893-901
    Hjerpe A; Abd-Own S; Dobra K
  • Article: BMC CELL BIOLOGY. 2017;18(1):34
    Szatmari T; Mundt F; Kumar-Singh A; Mobus L; Otvos R; Hjerpe A; Dobra K
  • Article: CANCER CYTOPATHOLOGY. 2017;125(12):908-917
    Mansour MSI; Seidal T; Mager U; Baigi A; Dobra K; Dejmek A
  • Journal article: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):s2021
    Mansour M; Seidal T; Mager U; Baigi A; Dobra K; Dejmek A
  • Article: ONCOTARGET. 2017;8(47):82885-82896
    Hillerdal C-O; Otvos R; Szatmari T; Abd Own S; Hillerdal G; Dackland A-L; Dobra K; Hjerpe A
  • Article: MATRIX BIOLOGY. 2017;59:3-22
    Karousou E; Misra S; Ghatak S; Dobra K; Goette M; Vigetti D; Passi A; Karamanos NK; Skandalis SS
  • Journal article: EURASIAN JOURNAL OF PULMONOLOGY. 2017;19(3):130-138
    Arslan S; Mundt F; Metintas S; Ak G; Dobra K; Hjerpe A; Metintas M
  • Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2016;14(1):295
    Robles AI; Olsen KS; Tsui DWT; Georgoulias V; Creaney J; Dobra K; Vyberg M; Minato N; Anders RA; Borresen-Dale A-L; Zhou J; Saetrom P; Nielsen BS; Kirschner MB; Krokan HE; Papadimitrakopoulou V; Tsamardinos I; Roe OD
  • Article: CLINICAL NUCLEAR MEDICINE. 2016;41(4):263-267
    Uhlen N; Grundberg O; Jacobsson H; Sundin A; Dobra K; Sanchez-Crespo A; Axelsson R; Kolbeck K-G
  • Journal article: PLEURA AND PERITONEUM. 2016;1(3):119-133
    Szulkin A; Szatmari T; Hjerpe A; Dobra K
  • Article: CELLULAR SIGNALLING. 2015;27(10):2054-2067
    Heidari-Hamedani G; Vives RR; Seffouh A; Afratis NA; Oosterhof A; van Kuppevelt TH; Karamanos NK; Metintas M; Hjerpe A; Dobra K; Szatmari T
  • Article: CANCER CYTOPATHOLOGY. 2015;123(8):449-453
    Hjerpe A; Dobra K
  • Article: DIAGNOSTIC CYTOPATHOLOGY. 2015;43(7):563-576
    Hjerpe A; Ascoli V; Bedrossian CWM; Boon ME; Creaney J; Davidson B; Dejmek A; Dobra K; Fassina A; Field A; Firat P; Kamei T; Kobayashi T; Michael CW; Onder S; Segal A; Vielh P
  • Article: GENES AND CANCER. 2015;6(3-4):119-128
    Ötvös R; Szulkin A; Hillerdal C-O; Celep A; Yousef-Fadhel E; Skribek H; Hjerpe A; Székely L; Dobra K
  • Article: ACTA CYTOLOGICA. 2015;59(1):2-16
    Hjerpe A; Ascoli V; Bedrossian CWM; Boon ME; Creaney J; Davidson B; Dejmek A; Dobra K; Fassina A; Field A; Firat P; Kamei T; Kobayashi T; Michael CW; Onder S; Segal A; Vielh P
  • Article: BMC CANCER. 2014;14:709
    Szulkin A; Otvos R; Hillerdal C-O; Celep A; Yousef-Fadhel E; Skribek H; Hjerpe A; Szekely L; Dobra K
  • Article: MOLECULAR & CELLULAR PROTEOMICS. 2014;13(3):701-715
    Mundt F; Johansson HJ; Forshed J; Arslan S; Metintas M; Dobra K; Lehtio J; Hjerpe A
  • Article: BIOMED RESEARCH INTERNATIONAL. 2014;2014:419853-11
    Mundt F; Heidari-Hamedani G; Nilsonne G; Metintas M; Hjerpe A; Dobra K
  • Article: PLOS ONE. 2013;8(6):e65903
    Szulkin A; Nilsonne G; Mundt F; Wasik AM; Souri P; Hjerpe A; Dobra K
  • Article: PLOS ONE. 2013;8(8):e72030
    Mundt F; Nilsonne G; Arslan S; Csuros K; Hillerdal G; Yildirim H; Metintas M; Dobra K; Hjerpe A
  • Article: FRONTIERS IN ONCOLOGY. 2013;3:203
    Darai-Ramqvist E; Nilsonne G; Flores-Staino C; Hjerpe A; Dobra K
  • Article: PLOS ONE. 2012;7(10):e48091
    Szatmari T; Mundt F; Heidari-Hamedani G; Zong F; Ferolla E; Alexeyenko A; Hjerpe A; Dobra K
  • Article: PLOS ONE. 2012;7(8):e40521
    Roe OD; Szulkin A; Anderssen E; Flatberg A; Sandeck H; Amundsen T; Erlandsen SE; Dobra K; Sundstrom SH
  • Article: PLOS ONE. 2012;7(6):e39474
    Peterfia B; Fuele T; Baghy K; Szabadkai K; Fullar A; Dobos K; Zong F; Dobra K; Hollosi P; Jeney A; Paku S; Kovalszky I
  • Article: JOURNAL OF IMMUNOLOGY. 2011;187(7):3546-3554
    Enqvist M; Nilsonne G; Hammarfjord O; Wallin RPA; Bjoerkstroem NK; Bjornstedt M; Hjerpe A; Ljunggren H-G; Dobra K; Malmberg K-J; Carlsten M
  • Article: BMC CANCER. 2011;11:314
    Skandalis SS; Labropoulou VT; Ravazoula P; Likaki-Karatza E; Dobra K; Kalofonos HP; Karamanos NK; Theocharis AD
  • Article: PLOS ONE. 2011;6(6):e14816
    Zong F; Fthenou E; Mundt F; Szatmari T; Kovalszky I; Szilak L; Brodin D; Tzanakakis G; Hjerpe A; Dobra K
  • Article: INTERNATIONAL JOURNAL OF CANCER. 2010;127(9):1999-2008
    An Z; Dobra K; Lock JG; Stromblad S; Hjerpe A; Zhang H
  • Article: LUNG CANCER. 2010;68(1):39-43
    Flores-Staino C; Darai-Ramqvist E; Dobra K; Hjerpe A
  • Article: CELL PROLIFERATION. 2010;43(1):29-40
    Zong F; Fthenou E; Castro J; Peterfia B; Kovalszky I; Szilak L; Tzanakakis G; Dobra K
  • Article: PLOS ONE. 2009;4(10):e7346
    Zong F; Fthenou E; Wolmer N; Hollosi P; Kovalszky I; Szilak L; Mogler C; Nilsonne G; Tzanakakis G; Dobra K
  • Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2009;28(1):92
    Nilsonne G; Olm E; Szulkin A; Mundt F; Stein A; Kocic B; Rundlof A-K; Fernandes AP; Bjornstedt M; Dobra K
  • Article: IN VIVO. 2009;23(1):69-76
    Fthenou E; Zong F; Zafiropoulos A; Dobra K; Hjerpe A; Tzanakakis GN
  • Article: CONNECTIVE TISSUE RESEARCH. 2008;49(3-4):270-272
    Dobra K; Hjerpe A
  • Article: CONNECTIVE TISSUE RESEARCH. 2008;49(3-4):249-251
    Hjerpe A; Dobra K
  • Article: DIFFERENTIATION. 2007;75(2):123-132
    Rundlof A-K; Fernandes AP; Selenius M; Babic M; Shariatgorji M; Nilsonne G; Ilag LL; Dobra K; Bjornstedt M
  • Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(46):35116-35128
    Theocharis AD; Seidel C; Borset M; Dobra K; Baykov V; Labropoulou V; Kanakis I; Dalas E; Karamanos NK; Sundan A; Hjerpe A
  • Article: FREE RADICAL BIOLOGY AND MEDICINE. 2006;41(6):874-885
    Nilsonne G; Sun X; Nyström C; Rundlöf A-K; Potamitou Fernandes A; Björnstedt M; Dobra K
  • Article: CANCER LETTERS. 2006;232(2):161-169
    Sun XJ; Gulyás M; Hjerpe A; Dobra K
  • Article: JOURNAL OF PATHOLOGY. 2005;207(1):91-101
    Sun XJ; Wei L; Lidén J; Hui G; Dahlman-Wright K; Hjerpe A; Dobra K
  • Article: ANTICANCER RESEARCH. 2004;24(2B):599-603
    Liu ZW; Dobra K; Hauzenberger D; Klominek J
  • Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2004;34(4):797-801
    Seidel C; Gulyás M; David G; Dobra K; Theocharis AD; Hjerpe A
  • Article: ANTICANCER RESEARCH. 2003;23(3B):2435-2444
    Dobra K; Nurminen M; Hjerpe A
  • Article: ANTICANCER RESEARCH. 2002;22(6C):4157-4162
    Syrokou A; Dobra K; Tzanakakis GN; Hjerpe A; Karamanos NK
  • Article: EXPERIMENTAL CELL RESEARCH. 2002;274(2):235-245
    Brockstedt U; Dobra K; Nurminen M; Hjerpe A
  • Journal article: JOURNAL OF MUSCULOSKELETAL RESEARCH. 2001;5(02):79-88
    Dobra K; Hjerpe A
  • Article: DIFFERENTIATION. 2000;66(4-5):181-188
    Sun XJ; Dobra K; Björnstedt M; Hjerpe A
  • Article: AMERICAN JOURNAL OF CLINICAL PATHOLOGY. 2000;114(2):203-209
    Brockstedt U; Gulyas M; Dobra K; Dejmek A; Hjerpe A
  • Article: EXPERIMENTAL CELL RESEARCH. 2000;258(1):12-22
    Dobra K; Andäng M; Syrokou A; Karamanos NK; Hjerpe A
  • Article: DIFFERENTIATION. 1999;65(2):89-96
    Gulyás M; Dobra K; Hjerpe A
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All other publications

  • Preprint: PREPRINTS.ORG. 2024
    Rosier M; Krstulović A; Kim HR; Kaur N; Enakireru EM; Symmes D; Dobra K; Chen R; Evans C; Gad A
  • Book chapter: THE EXTRACELLULAR MATRIX AND THE TUMOR MICROENVIRONMENT: BIOLOGY OF EXTRACELLULAR MATRIX. 2022;p. 49-73
    Kovalszky I; Baghy K; Reszegi A; Hollósi P; Hjerpe A; Dobra K
  • Review: ACTA CYTOLOGICA. 2021;65(6):501-509
    Mansour MSI; Lindquist KE; Seidal T; Mager U; Mohlin R; Tran L; Hejny K; Holmgren B; Violidaki D; Dobra K; Dejmek A; Planck M; Brunnstrom H
  • Review: TRANSLATIONAL LUNG CANCER RESEARCH. 2020;9(3):934-943
    Hjerpe A; Own SA; Dobra K
  • Review: CYTOPATHOLOGY. 2019;30(1):31-38
    Engels M; Michael C; Dobra K; Hjerpe A; Fassina A; Firat P
  • Conference publication: JOURNAL OF HEPATOLOGY. 2018;68:S217
    von Seth E; Ouchterlony H; Haas S; Dobra K; Hjerpe A; Bergquist AM
  • Book chapter: SEROUS EFFUSIONS. 2018;p. 259-281
    Dobra K; Hjerpe A
  • Book chapter: SEROUS EFFUSIONS. 2018;p. 171-189
    Dobra K; Hjerpe A
  • Conference publication: JOURNAL OF THORACIC ONCOLOGY. 2017;12(11):S2020
    Mansour M; Seidal T; Mager U; Baigi A; Dobra K; Dejmek A
  • Review: PLEURA AND PERITONEUM. 2016;1(3):119-133
    Szulkin A; Szatmári T; Hjerpe A; Dobra K
  • Corrigendum: CELLULAR SIGNALLING. 2015;27(12):2599-2600
    Heidari-Hamedani G; Vives RR; Seffouh A; Afratis NA; Oosterhof A; van Kuppevelt TH; Karamanos NK; Metintas M; Hjerpe A; Dobra K; Szatmari T
  • Review: CYTOPATHOLOGY. 2015;26(3):142-156
    Hjerpe A; Ascoli V; Bedrossian CWM; Boon ME; Creaney J; Davidson B; Dejmek A; Dobra K; Fassina A; Field A; Firat P; Kamei T; Kobayashi T; Michael CW; Onder S; Segal A; Vie P
  • Review: DISEASE MARKERS. 2015;2015:796052-13
    Szatmari T; Otvos R; Hjerpe A; Dobra K
  • Review: CYTOJOURNAL. 2015;12:26
    Hjerpe A; Ascoli V; Bedrossian C; Boon M; Creaney J; Davidson B; Dejmek A; Dobra K; Fassina A; Field A; Firat P; Kamei T; Kobayashi T; Michael CW; Tnder S; Segal A; Vielh P
  • Editorial comment: BIOMED RESEARCH INTERNATIONAL. 2015;2015:482879-2
    Skandalis SS; Dobra K; Goette M; Karousou E; Misra S
  • Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1840(8):2491-2497
    Kovalszky I; Hjerpe A; Dobra K
  • Review: FRONTIERS IN ONCOLOGY. 2013;3:310
    Szatmari T; Dobra K
  • Book chapter: SEROUS EFFUSIONS. 2012;p. 151-165
    Dobra K; Hjerpe A
  • Book chapter: SEROUS EFFUSIONS. 2012;p. 225-240
    Dobra K; Hjerpe A
  • Meeting abstract: LUNG CANCER. 2006;54:S52
    Nilsonne G; Stein A; Rundloef A-K; Fernandes AP; Bjoernstedt M; Hjerpe A; Dobra K
  • Conference publication: ANTICANCER RESEARCH. 2004;24(5D):3473
    Nilsonne G; Sun X; Nystrom C; Rundlof A-K; Nurminen M; Bjornstedt M; Dobra K
  • Doctoral thesis: 2002
    Dobra K
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Employments

  • Professor/Senior Physician, Department of Oncology-Pathology, ̽»¨¾«Ñ¡, 2022-

Degrees and Education

  • Docent, ̽»¨¾«Ñ¡, 2010
  • Doctor Of Philosophy, Department of Laboratory Medicine, ̽»¨¾«Ñ¡, 2002

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