̽»¨¾«Ñ¡

Kaarina Kowalec

Kaarina Kowalec

Affiliated to Research
Visiting address: Nobelsvägen 12a, 17165 SOLNA
Postal address: C8 Medicinsk epidemiologi och biostatistik, C8 MEB I Lu, 171 77 Stockholm

About me

  • I am a tenure-track Assistant Professor position at the Rady Faculty of Health Sciences at University of Manitoba and hold an Affiliated Research
    position at the ̽»¨¾«Ñ¡. My research aims to identify precision medicine approaches to neurological diseases and psychiatric disorders by combining genomics, biostatistics, and epidemiology, to advance the outcomes of those affected by neurological and psychiatric disorders. Our work regularly involves an extensive network of Canadian, American, Swedish, and other International collaborators. I am funded by the US Department of Defense, US NIMH and the Consortium of Multiple Sclerosis Centres. We are a "dry-lab" focussed on computation and analysis, but collaborate with "wet-lab" groups internationally.


    During my postdoctoral and PhD studies, I held fellowships from the European Commission (Horizon-2020), and the Canadian Institutes of Health Research (CIHR), including the Marie Skłodowska-Curie Actions-Horizon 2020 European Fellowship (€180K) and the Government of Canada Banting Fellowship, with over 20 awards during my PhD alone, totalling over $960K in personal salary awards, and $1.8M in peer-reviewed operating and team grants. From 2017-19, I was a Postdoctoral researcher at the Karolinska Institute with Professor Patrick Sullivan and the KI-Psychiatric Genomics Institute to harness my collaborative, problem-solving abilities that I have developed during my doctoral training and apply them to the intricate issues faced today by the psychiatric community. My projects involved utilizing the Swedish National Register data, the Sweden Schizophrenia Study, and other psychiatric cohort studies.

Research

  • Theme 1: Epidemiology and genomics of poor outcomes in schizophrenia
    Schizophrenia (SCZ) is one of the top 15 leading causes of disability worldwide, with the average number of life years lost ~30 years. Those with SCZ are at 15-25 times higher risk for suicide, compared to the general population. It is currently estimated that ~200, 000 Canadians have SCZ. In 2004, the direct healthcare and non-healthcare costs related to SCZ in Canada were estimated at >$2B, and when considering additional losses, resulted in a total cost estimate of $6.85B. Features associated with poor outcomes in SCZ include childhood adversities (e.g. neglect), family history of psychiatric disorders, and SCZ genomic burden (the weighted sum of the number of SCZ genetic risk variants within each individual). There are currently no means of predicting, at first clinical presentation, who will experience a poor outcome in SCZ. Our overall goal is early detection of those at high risk for poor outcomes in SCZ, thereby triggering logical and effective interventions to mitigate the personal, social, and societal costs associated with severe SCZ. Our overarching translational goal is to develop valid and clinically useful models that predict crucial clinical outcomes for psychiatry and to implement the predictive models on a provincial and national scale.

    Projects:
    1. Investigating the association between accelerated DNA methylation age and mortality in SCZ. This work is published in .
    2. Using population-based Swedish National register data and extensive genomic data to examine treatment resistance in schizophrenia (published in ).​â¶Ä‹
    3. Investigating the role of genetic variation in association with specific and all cause mortality in schizophrenia. This work is published in .

     

    Theme 2: Epidemiology and genomics of poor outcomes in multiple sclerosis (MS) and other chronic immunoinflammatory diseases

    The prevention of poor outcomes, such as serious adverse drug reactions associated with MS therapies or the development of psychiatric disorders, is essential for those with MS and other chronic immunoinflammatory diseases. Currently, there are few clinically useful predictors of poor outcomes in MS. Variability in the genes that underscore drug biotransformation may be the key to identifying and predicting who is at greatest risk of serious adverse drug reactions and likewise, investigating the genes that underlie polygenic traits like psychiatric disorders, may also be important in investigating those at greatest risk for a psychiatric disorder. Findings from our cutting-edge work (published in ,  ,  ,  ,  and ) could improve outcomes in MS and contribute to the future development of precision medicine approaches to MS and other autoimmune diseases.

    Projects:
    1. Understanding psychiatric comorbidity in chronic immunoinflammatory diseases using genomics​:  ​We published work modelling longitudinal depressive symptoms in IMID to understand their evolution and identify any associated factors (including polygenic risk scores), with the overall goal of identifying those at highest risk of higher depressive symptom burden. This work is published in . We then followed this with an assessment of depression polygenicity in multiple sclerosis and this work is published in  and an assessment of anxiety polygenicity in MS, published in . We also aimed to better understand the bidirectional relationship between multiple sclerosis and depression using Mendelian randomization and found no evidence for a causal role for this relationship. This was published in .
    2. Understanding factors associated with substance use disorder in those with inflammatory bowel disease and rheumatoid arthritis in Manitoba. These projects are now published in  and .
    3. Genomic variants associated with DMF induced lymphopenia in MS [GenDMF-MS]: Seeking to predict and ultimately prevent adverse drug reactions in people with MS. An international pharmacogenomic investigation of lymphopenia due to dimethyl fumarate in multiple sclerosis, funded by the . The protocol for this work can be found  and the project is in the analysis stage.

Teaching

  • 2024

    • Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed ~50 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
    • Lecturer, College of Pharmacy, University of Manitoba PHMD2004: Instructed ~50 students in Critical Appraisal Pharmacotherapy Literature 1 (One 3-hour lecture)
    • Mentor,  College of Pharmacy, University of Manitoba PHMD4000: Instructed 6 fourth year PharmD students in a research project (12 weeks each).

    2023

    • Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed 35 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
    • Lecturer, College of Pharmacy, University of Manitoba PHRM7102: Instructed 8 graduate students in Pharmacoepidemiology (One 3-hour lecture).

    2022

    • Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed 55 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
    • Mentor, College of Pharmacy, University of Manitoba PHMD4000: Instructed two fourth year PharmD students in a research project (12 weeks each).

    2021

    • Lecturer, College of Pharmacy, University of Manitoba PHMD2012: Planned the course syllabus and pre-recorded 10 lectures to be given as part of the Pharmacogenetics course (60-minutes each).

    2020

    • Lecturer, College of Pharmacy, University of Manitoba PHRM3640: Instructed 55 undergraduate Pharmacy students in Principles of Biotechnology (8 lectures of 75-minutes each).

    2019

    • Lecturer, College of Pharmacy, University of Manitoba PHRM4470: Current Topics in Pharmacy (1 hour)
    • Lecturer, College of Pharmacy, University of Manitoba PHRM7260: Instructed 1 lecture of Pharmacy Graduate Student Seminar (1 hour)
    • Lecturer, College of Pharmacy, University of Manitoba PHRM3520: Instructed 55 undergraduate Pharmacy students in Scientific Literature Evaluation (5 lectures of 90-minutes each).
    • Lecturer, University of North Carolina-Chapel Hill and ̽»¨¾«Ñ¡: Instructed 20 researchers in R-Statistical Software tutoria
    • Teaching and Learning Certificate, University of Manitoba: Two-year program designed to develop the knowledge, skills, and reflective practice.

    2012-2016

    • Teaching Assistant, Department of Biochemistry & Molecular Biology, Faculty of Science, UBC: Instructed undergraduate weekly laboratory session; monitored and assisted student biochemical and molecular biology experiments; evaluated student assignments, examinations, and progress; consistently rated highly amongst third-year undergraduate students.

    2011-2012

    • Laboratory Instructor, Biology Program, Faculty of Science, UBC: BIOL 140 Laboratory Investigations in Life Science: Instructed weekly laboratory sessions and preparatory sessions to enable students to participate in the scientific process; facilitated discussions with students and recorded student progress; assessed student work (assignments, written work, exams) and kept accurate records of student attendance, participation, and marks.

    2008-2009

    • Problem-Based Learning Facilitator, Rady College of Medicine, Department of Medical Microbiology, University of Manitoba

Articles

  • Article: EBIOMEDICINE. 2025;112:105576
    Nguyen T-D; Meijsen JJ; Sigstroem R; Kuja-Halkola R; Xiong Y; Harder A; Kowalec K; Pasman JA; Scarpa C; Horbeck E; Jonsson L; Hagg S; Mullins N; O'Connell KS; Dalman C; Helenius D; Zetterberg R; Larsson H; Lichtenstein P; Andreassen OA; Werge T; Buil A; Landen M; Sullivan PF; Lu Y
  • Article: JAMA PSYCHIATRY. 2024;81(12):1246-1252
    Song J; Pasman JA; Johansson V; Kuja-Halkola R; Harder A; Karlsson R; Lu Y; Kowalec K; Pedersen NL; Cannon TD; Hultman CM; Sullivan PF
  • Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2024;91:105866
    Hu C; Vasileiou ES; Salter A; Marrie RA; Kowalec K; Fitzgerald KC
  • Article: SCHIZOPHRENIA RESEARCH. 2024;272:69-76
    Shirinbakhshmasoleh M; Aboulatta L; Leong C; Riel H; Liu K; Delaney JC; Bolton JM; Falk J; Alessi-Severini S; Eltonsy S; Kowalec K
  • Article: JAMA NEUROLOGY. 2024;81(11):1170-1177
    Salter A; Lancia S; Kowalec K; Fitzgerald KC; Marrie RA
  • Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2024;11(6):1393-1404
    Kowalec K; Harder A; Dolovich C; Fitzgerald KC; Salter A; Lu Y; Bernstein CN; Bolton JM; Cutter G; Fisk JD; Gelernter J; Graff LA; Haegg S; Hitchon CA; Levey DF; Lublin FD; Mckay KA; Patten S; Patki A; Stein MB; Tiwari HK; Wolinsky JS; Marrie RA
  • Article: BMJ GLOBAL HEALTH. 2024;9(5):e015098
    Schindell BG; Fredborg B; Kowalec K; Shaw S; Kangbai JB; Kindrachuk J
  • Article: NEUROLOGY. 2024;102(5):e209135
    Salter A; Lancia S; Kowalec K; Fitzgerald KC; Marrie RA
  • Article: PHARMACOGENOMICS. 2024;25(4):175-186
    Al Maruf A; Shields M; Fryza A; Wondrasek A; Leong C; Kowalec K; Bousman C
  • Article: HEALTH SCIENCE REPORTS. 2024;7(1):e1844
    Wondrasek A; Fryza A; Aziz MA; Leong C; Kowalec K; Al Maruf A
  • Article: FRONTIERS IN PHARMACOLOGY. 2024;15:1469552
    Peymani P; Berard A; Winquist B; Kaul P; Sheehy O; Lavu A; Leong C; Falk J; Delaney JA; Kowalec K; Ng M; Ruth C; Aboulatta L; Alessi-Severini S; Dragan R; Derksen S; Barrett O; Shams G; Eltonsy S
  • Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(10):714-722
    Thuy-Dung N; Kowalec K; Pasman J; Larsson H; Lichtenstein P; Dalman C; Sullivan PF; Kuja-Halkola R; Lu Y
  • Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):301
    Xiong Y; Karlsson R; Song J; Kowalec K; Rueck C; Sigstroem R; Jonsson L; Clements CC; Andersson E; Boberg J; Lewis CM; Sullivan PF; Landen M; Lu Y
  • Article: JOURNAL OF PSYCHOSOMATIC RESEARCH. 2023;172:111415
    Marrie RA; Lix LM; Bolton JM; Fisk JD; Fitzgerald KC; Graff LA; Hitchon CA; Kowalec K; Marriott JJ; Patten SB; Salter A; Bernstein CN
  • Article: NEUROLOGY. 2023;101(5):e522-e532
    Kowalec K; Fitzgerald KC; Salter A; Dolovich C; Harder A; Bernstein CN; Bolton J; Cutter GR; Graff LA; Hagg S; Hitchon CA; Lu Y; Lublin F; McKay KA; Patten SB; Patki A; Tiwari HK; Wolinsky JS; Marrie RA
  • Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2023;43(4):313-319
    Froese B; Aquino G; Valencia E; Tan Q; Yogendran M; Katz C; Bolton JM; Falk J; Kowalec K; Chateau D; Delaney JC; Logsetty S; Spiwak R; Enns MW; Sareen J; Alessi-Severini S; Olafson K; Eltonsy S; Leong C
  • Journal article: BMJ OPEN. 2023;13(6):e073782
    Almweisheer S; Bernstein CN; Graff LA; Patten SB; Bolton J; Fisk JD; Hitchon CA; Marriott JJ; Marrie RA; CIHR Team in Defining the Burden and Managing the
  • Article: LANCET REGIONAL HEALTH-EUROPE. 2023;29:100621
    Pasman JA; Meijsen J; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lua Y
  • Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACY. 2023;45(1):233-239
    Offiah R; Aboulatta L; Peymani P; Aloud B; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Eltonsy S
  • Article: BMJ PAEDIATRICS OPEN. 2023;7(1):e001686
    Aboulatta L; Kowalec K; Leong C; Delaney JA; Falk J; Alessi-Severini S; Chateau D; Tan Q; Kearns K; Raimondi C; Vaccaro C; Lavu A; Haidar L; Peymani P; Eltonsy S
  • Article: FRONTIERS IN PSYCHIATRY. 2023;14:1260420
    Joyees J; Marrie RA; Bernstein CN; Bolton JM; Fisk JD; Graff LA; Hitchon C; Patten SB; Kowalec K
  • Article: NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2023;10(1):e200062
    Vasileiou ES; Hu C; Bernstein CN; Lublin F; Wolinsky JS; Cutter GR; Sotirchos ES; Kowalec K; Salter A; Saidha S; Mowry EM; Calabresi PA; Marrie RA; Fitzgerald KC
  • Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(11):844-852
    Sigstrom R; Kowalec K; Jonsson L; Clements CC; Karlsson R; Nordenskjold A; Palsson E; Sullivan PF; Landen M
  • Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e198
    Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hägg S; Hitchon C; Bernstein CN; Cutter G; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
  • Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e31-e32
    Lu Y; Kowalec K; Werge T; Andreassen O; Sullivan P
  • Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e270
    Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M; Lu Y
  • Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e32-e33
    Kowalec K; Karlsson R; Lu Y; Song J; Yao S; Szatkiewicz J; Kähler A; Schalling M; Österholm A-M; Hultman C; Lavebratt C; Landen M; Karlsson H; Dalman C; Sullivan P
  • Article: GENERAL HOSPITAL PSYCHIATRY. 2022;77:21-28
    Kowalec K; Salter A; Fitzgerald KC; Patel M; Han J; Lu Y; Bolton JM; Hitchon C; Bernstein CN; Patten S; Graff LA; Marriott JJ; Marrie RA
  • Article: BMC RESEARCH NOTES. 2022;15(1):162
    Aboulatta L; Kowalec K; Delaney J; Alessi-Severini S; Leong C; Falk J; Eltonsy S
  • Article: MOLECULAR PSYCHIATRY. 2022;27(5):2439-2447
    Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz JP; Larsson H; Lichtenstein P; Hultman CM; Sullivan PF
  • Article: JAMA PSYCHIATRY. 2022;79(3):260-269
    Pardinas AF; Smart SE; Willcocks IR; Holmans PA; Dennison CA; Lynham AJ; Legge SE; Baune BT; Bigdeli TB; Cairns MJ; Corvin A; Fanous AH; Frank J; Kelly B; McQuillin A; Melle I; Mortensen PB; Mowry BJ; Pato CN; Periyasamy S; Rietschel M; Rujescu D; Simonsen C; St Clair D; Tooney P; Wu JQ; Andreassen OA; Kowalec K; Sullivan PF; Murray RM; Owen MJ; MacCabe JH; O'Donovan MC; Walters JTR
  • Article: MOLECULAR PSYCHIATRY. 2022;27(3):1667-1675
    Thuy-Dung N; Harder A; Xiong Y; Kowalec K; Hagg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan PF; Lu Y
  • Article: PLOS ONE. 2022;17(11):e0278072
    Aboulatta L; Peymani P; Vaccaro C; Leong C; Kowalec K; Delaney J; Falk J; Alessi-Severini S; Aloud B; Eltonsy S
  • Article: FRONTIERS IN PHARMACOLOGY. 2022;13:886652
    Leong C; Kowalec K; Eltonsy S; Bolton JM; Enns MW; Tan Q; Yogendran M; Chateau D; Delaney JA; Sareen J; Falk J; Spiwak R; Logsetty S; Alessi-Severini S
  • Article: FRONTIERS IN PHARMACOLOGY. 2022;13:871136
    Shouman W; Delaney JA; Kowalec K; Ng M; Ruth C; Falk J; Leong C; Alessi-Severini S; Lavu A; Peymani P; Eltonsy S
  • Article: ACR OPEN RHEUMATOLOGY. 2021;3(12):889-896
    Kowalec K; Carney H; Patel M; Hitchon C; Bolton JM; Patten SB; Graff LA; Bernstein CN; Peschken C; Marrie RA
  • Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(13):2077-2084
    Harroud A; Marrie RA; Fitzgerald KC; Salter A; Lu Y; Patel M; Kowalec K
  • Article: MOLECULAR PSYCHIATRY. 2021;26(8):4487-4495
    Kowalec K; Lu Y; Sariaslan A; Song J; Ploner A; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
  • Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):163
    Kowalec K; Lu Y; Song J; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
  • Article: ELIFE. 2021;10:e58430
    Hannon E; Dempster EL; Mansell G; Burrage J; Bass N; Bohlken MM; Corvin A; Curtis CJ; Dempster D; Di Forti M; Dinan TG; Donohoe G; Gaughran F; Gill M; Gillespie A; Gunasinghe C; Hulshoff HE; Hultman CM; Johansson V; Kahn RS; Kaprio J; Kenis G; Kowalec K; MacCabe J; McDonald C; McQuillin A; Morris DW; Murphy KC; Mustard CJ; Nenadic I; O'Donovan MC; Quattrone D; Richards AL; Rutten BP; St Clair D; Therman S; Toulopoulou T; Van Os J; Waddington JL; Sullivan P; Vassos E; Breen G; Collier DA; Murray RM; Schalkwyk LS; Mill J
  • Article: INFLAMMATORY BOWEL DISEASES. 2021;27(1):58-64
    Carney H; Marrie RA; Bolton JM; Patten SB; Graff LA; Bernstein CN; Kowalec K
  • Article: NEUROLOGY. 2020;95(5):e446-e456
    Salter A; Kowalec K; Fitzgerald KC; Cutter G; Marrie RA
  • Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s236
    Kowalec K; Bernstein CN; Hitchon C; Bolton J; Marrie RA
  • Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):157
    Kowalec K; Hannon H; Mansell G; Burrage J; Ori APS; Ophoff RA; Mill J; Sullivan PF
  • Article: NATURE GENETICS. 2018;50(8):1081-1085
    Kowalec K; Wright GEB; Drogemoller BI; Aminkeng F; Bhavsar AP; Kingwell E; Yoshida EM; Traboulsee A; Marrie RA; Kremenchutzky M; Campbell TL; Duquette P; Chalasani N; Wadelius M; Hallberg P; Xia Z; De Jager PL; Denny JC; Davis MF; Ross CJD; Tremlett H; Carleton BC
  • Article: NEUROLOGY. 2018;90(4):e332-e341
    McCormack M; Gui H; Ingason A; Speed D; Wright GEB; Zhang EJ; Secolin R; Yasuda C; Kwok M; Wolking S; Becker F; Rau S; Avbersek A; Heggeli K; Leu C; Depondt C; Sills GJ; Marson AG; Auce P; Brodie MJ; Francis B; Johnson MR; Koeleman BPC; Striano P; Coppola A; Zara F; Kunz WS; Sander JW; Lerche H; Klein KM; Weckhuysen S; Krenn M; Gudmundsson LJ; Stefansson K; Krause R; Shear N; Ross CJD; Delanty N; Pirmohamed M; Carleton BC; Cendes F; Lopes-Cendes I; Liao W-P; O'Brien TJ; Sisodiya SM; Cherny S; Kwan P; Baum L; Cavalleri GL
  • Article: NEUROLOGY. 2017;89(24):2455-2461
    Kowalec K; McKay KA; Patten SB; Fisk JD; Evans C; Tremlett H; Marrie RA
  • Journal article: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017;88:173
    Kowalec K; Wright GEB; Drögemöller BI; Aminkeng F; Bhavsar AP; Kingwell E; Yoshida EM; Traboulsee A; Marrie RA; Kremenchutzky M; Campbell TL; Duquette P; Chalasani N; Wadelius M; Hallberg P; Xia Z; De Jager P; Ross C; Tremlett H; Carleton B
  • Journal article: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017;88:167
    Abel S; Aminkeng F; Kowalec K; Drogemoller B; Wright G; Bader R; Stortz J; Yoshida E; Lee S; Al-Judaibi B; Kim R; Tam E; Ramji A; Ross C; Carleton B
  • Article: BMJ OPEN. 2017;7(5):e016276
    Kowalec K; Kingwell E; Carruthers R; Marrie RA; Bernatsky S; Traboulsee A; Ross CJD; Carleton B; Tremlett H
  • Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2016;85(3):328-333
    Osiowy C; Kowalec K; Giles E
  • Article: NATURE GENETICS. 2015;47(9):1079-1084
    Aminkeng F; Bhavsar AP; Visscher H; Rassekh SR; Li Y; Lee JW; Brunham LR; Caron HN; van Dalen EC; Kremer LC; van der Pal HJ; Amstutz U; Rieder MJ; Bernstein D; Carleton BC; Hayden MR; Ross CJD
  • Article: JOURNAL OF VIRAL HEPATITIS. 2013;20(2):122-130
    Kowalec K; Minuk GY; Borresen ML; Koch A; McMahon BJ; Simons B; Osiowy C
  • Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2013;2(1):57-59
    Kowalec K; Yoshida EM; Traboulsee A; Carleton B; Tremlett H
  • Article: JOURNAL OF MEDICAL VIROLOGY. 2012;84(9):1369-1375
    Minuk GY; Kowalec K; Caouette S; Larke B; Osiowy C
  • Article: JOURNAL OF MEDICAL VIROLOGY. 2010;82(6):942-948
    Osiowy C; Kaita K; Solar K; Mendoza K
  • Show more

All other publications

  • Corrigendum: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2024;44(3):211
    Froese B; Aquino G; Valencia E; Tan Q; Yogendran M; Katz C; Bolton JM; Falk J; Kowalec K; Chateau D; Delaney JC; Logsetty S; Spiwak R; Enns MW; Sareen J; Alessi-Severini S; Olafson K; Eltonsy S; Leong C
  • Preprint: MEDRXIV. 2023
    Lu Y; Kowalec K; Song J; Karlsson R; Harder A; Giusti-Rodríguez P; Sullivan PF; Yao S
  • Preprint: RES SQ. 2023;RES SQ
    Lu Y; Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigstrom R; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M
  • Review: FRONTIERS IN IMMUNOLOGY. 2023;14:1197195
    Marrie RA; Fisk JD; Fitzgerald K; Kowalec K; Maxwell C; Rotstein D; Salter A; Tremlett H
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E159
    Kowalec K; Song J; Yao S; Karlsson R; Lu Y; Bergen S; Harder A; Kahler A; Osterholm A-M; Hultman C; Sullivan P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E50
    Thi TDN; Kuja-Halkola R; Kowalec K; Harder A; Xiong Y; Landen M; Hagg S; Lichtenstein P; Larsson H; Buil A; Meijsen J; Sullivan P; Dalman C; Pasman J; Lu Y
  • Preprint: MEDRXIV. 2022
    Aboulatta L; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Chateau D; Tan Q; Kearns K; Raimondi C; Lavu A; Haidar L; Vaccaro C; Eltonsy S
  • Review: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2022;111(4):919-930
    Johnson D; Wilke MAP; Lyle SM; Kowalec K; Jorgensen A; Wright GEB; Drogemoller BI
  • Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):212
    Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hagg S; Hitchon C; Bernstein CN; Cutter G; Marriott JJ; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
  • Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(1_SUPPL):52
    Hu C; Marrie RA; Salter A; Kowalec K; Fitzgerald K
  • Conference publication: BIRTH DEFECTS RESEARCH. 2022;114(9):395
    Aboulatta L; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Eltonsy S
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E137-E138
    Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz J; Larsson H; Lichtenstein P; Hultman C; Sullivan P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E237
    Yao S; Lu Y; Kowalec K; Song J; Karlsson R; Harder A; Sullivan P
  • Review: PSYCHOLOGICAL MEDICINE. 2021;51(13):2168-2177
    Legge SE; Santoro ML; Periyasamy S; Okewole A; Arsalan A; Kowalec K
  • Preprint: MEDRXIV. 2021
    Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan P; Lu Y
  • Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(1_SUPPL):58-59
    Harroud A; Marrie R; Richards B; Fitzgerald K; Salter A; Lu Y; Patel M; Kowalec K
  • Preprint: BIORXIV. 2020
    Hannon E; Dempster EL; Mansell G; Burrage J; Bass N; Bohlken MM; Corvin A; Curtis CJ; Dempster D; Di Forta M; Dinan TG; Donohoe G; Gaughran F; Gill M; Gillespie A; Gunasinghe C; Hulshoff HE; Hultman CM; Johansson V; Kahn RS; Kaprio J; Kenis G; Kowalec K; MacCabe J; McDonald C; McQuillin A; Morris DW; Murphy KC; Mustard C; Nenadic I; O’Donovan MC; Quattrone D; Richards AL; Rutten BP; St Clair D; Therman S; Toulopoulou T; Van Os J; Waddington JL; Consortium WTCC; consortium CA; Sullivan P; Vassos E; Breen G; Collier DA; Murray R; Schalkwyk LS; Mill J
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S184
    Lu Y; Kowalec K; Drange OK; Tesli M; Weinsheimer S; Folkersen L; Werge T; Andreassen O; Reichborn-Kjennerud T; Sullivan P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S85-S86
    Kowalec K; Yi L; Drange OK; Weinsheimer S; Tesli M; Folkersen L; Werge T; Andreassen OA; Reichborn-Kjennerud T; Sullivan P
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S215
    Kowalec K; Yi L; Sariaslan A; Song J; Ploner A; Dalman C; Hultman C; Larsson H; Lichtenstein P; Sullivan P
  • Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:648
    Kowalec K; Bernstein CN; Hitchon C; Bolton J; Marrie RA
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1099-1100
    Hannon E; Dempster E; Mansell G; Schalkwyk L; Murray R; McQuillin A; Kowalec K; St Clair D; Morris D; Sullivan P; O'Donovan M; MacCabe J; Collier D; Mill J
  • Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1332-1333
    Kowalec K; Hannon E; Mansell G; Burrage J; Mill J; Sullivan P
  • Editorial comment: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2017;12:1-3
    Mckay KA; Kowalec K; Brinkman F; Finlay BB; Horwitz M; Manges AR; Osborne L; Tremlett H
  • Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2017;23:991
    Kowalec K; McKay K; Patten SB; Fisk JD; Evans C; Tremlett H; Marrie RA
  • Review: EXPERT OPINION ON DRUG SAFETY. 2014;13(10):1305-1317
    Kowalec K; Kingwell E; Yoshida EM; Marrie RA; Kremenchutzky M; Campbell TL; Wadelius M; Carleton B; Tremlett H
  • Review: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2013;2(3):183-192
    Kowalec K; Carleton B; Tremlett H
  • Show more

Grants

  • Capitalising on our differences: A gathering to better understand and advocate for Early Career Health Researchers in Canada
    Canadian Institutes of Health Research
    1 January 2023 - 31 December 2023
  • Precision Genomics Suite
    Canada Foundation for Innovation
    22 November 2022
  • Psychiatric Disorder Genomic Risk Scores as a Correlate of Disease Activity and Progression in Multiple Sclerosis
    Congressionally Directed Medical Research Programs
    15 July 2020 - 14 July 2024
  • Enhancing CAN-AIM capacity to respond to drug safety and effectiveness queries
    Canadian Institutes of Health Research
    1 September 2019 - 31 August 2022
  • Identifying Clinical, Demographic, & Genomic Risk Factors for Treatment-Resistant Psychiatric Disorders
    Canadian Institutes of Health Research
    1 April 2018 - 3 January 2019
  • The Drug Safety and Effectiveness Cross-Disciplinary Training (DSECT) Program
    Canadian Institutes of Health Research
    1 November 2015 - 28 February 2022
  • Genotype specific approaches to beta-interferon therapy in Multiple Sclerosis
    Canadian Institutes of Health Research
    1 May 2011 - 31 October 2014

Employments

  • Assistant Professor, Genetics, University of Manitoba, 2019-
  • Affiliated to Research, Department of Medical Epidemiology and Biostatistics, ̽»¨¾«Ñ¡, 2025-2027

Degrees and Education

  • PhD, Genetics and epidemiology, University of British Columbia, 2016
  • MSc, Viral genetics, University of Manitoba, 2011
  • BSc, Microbiology, University of Manitoba, 2008

News from KI

Events from KI