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Johan Lindberg

Johan Lindberg

Principal Researcher
Telephone: +46852482616
Visiting address: Nobels väg 12a, 17165 Solna
Postal address: C8 Medicinsk epidemiologi och biostatistik, C8 MEB Grönberg Lindberg, 171 77 Stockholm
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About me

  • Principal Researcher at the Department of Medical Epidemiology and Biostatistics (MEB), ̽»¨¾«Ñ¡, with a focus on biomarker discovery and cancer genomics assay development. Leading a multidisciplinary team comprising PhD students, postdocs, engineers, and bioinformaticians.

     

    My team has established and is responsible for a sample- and analysis process at KI/SciLife to enable biomarker driven randomized clinical trials and prospective research projects. The process encompasses reception and storage of biomaterial, subsequent processing for Illumina sequencing and analysis using an in-house developed bioinformatics pipeline and curation software. The setup is made possible through collaboration with KI biobank and Clinical Genomics at SciLife lab. Since 2016 >5500 samples from >50 hospitals in 6 European countries has been analysed and reported. The main studies have been ALASCCA and . The first result from the ProBio trial was and the ALASCCA trial met its primary endpoint which was recently presented at .

     

    The sample- and analysis process has been optimized, enabling a two-week turnover of results even to trial sites in other countries such as Belgium. Consequently, the weekly team activities have strong similarities to a routine diagnostic setting with tight timelines and uptime requirements. To give patients in clinical routine access to improved diagnostics and state-of-the art genomics the iPCM (implementation of Personalized Cancer Medicine) project was launched in late 2020 with the goal to implement the research infrastructure for genomic profiling in clinical routine at Clinical Pathology, Karolinska Hospital. Hitherto, genomic analysis of  and has been implemented as routine diagnostic tests with many more yet to come. 

Research

  • Cancer genomics, liquid biopsy, assay development, clinical trials. 

Teaching

  • Teaching subject area: Genetics, Cancer Genomics, Biotechnology, Bioinformatics. 

    Responsible for the annual course . The course is aimed towards PhD students and postdocs performing research in the subject area. 

    Course evaluations are available from and .

Articles

  • Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2025;43(4_SUPPL):lba125
    Martling A; Lindberg J; Myrberg IH; Nilbert M; Mayrhofer M; Gronberg H; Glimelius B; ALASCCA TSG
  • Article: CANCERS. 2024;16(22):3816
    Ofverholm I; Lin Y; Mondini J; Hardingz J; Braenstroem R; Tsagkozis P; Wirta V; Gellerbring A; Lindberg J; Chellappa V; Mayrhofer M; Haglund C; Haglund de Flon F; Wallander K
  • Article: NATURE MEDICINE. 2024;30(11):3291-3302
    De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjalm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Thellenberg Karlsson C; Janes E; Sandzen J; Schatteman P; Vigmostad M; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
  • Journal article: ANNALS OF ONCOLOGY. 2024;35:s991-s992
    Broer L; Oldenburg J; Mortezavi A; Lindberg J; Discacciati A; Karlsson CT; Ullen A; Janes E; Enblad G; Pettersson L; Vigmostad MN; Hjalm-Eriksson ME; Olsson M; Schatteman P; Ghysel C; De Laere B; Gronberg H; Ost P; Eklund M; Crippa A
  • Journal article: ANNALS OF ONCOLOGY. 2024;35:s978
    Kristiansen A; Sautois B; Crippa A; Mortezavi A; Discacciati A; Karlsson CT; Ullen A; Janes E; Enblad G; Oldenburg J; Sandzen J; Vigmostad MN; Hjalm-Eriksson ME; De Laere B; Strijbos MH; Ghysel C; Lindberg J; Eklund M; Ost P; Gronberg H
  • Journal article: ANNALS OF ONCOLOGY. 2024;35:s987
    Bultijnck R; Strijbos MH; Mortezavi A; Lindberg J; Discacciati A; Karlsson CT; Ullen A; Janes E; Enblad G; Oldenburg J; Sautois B; Hjalm-Eriksson ME; Haugnes HS; Schatteman P; Ghysel C; De Laere B; Eklund M; Gronberg H; Ost P; Crippa A
  • Journal article: ANNALS OF ONCOLOGY. 2024;35:s980
    Crippa A; Mortezavi A; Discacciati A; Karlsson CT; Strijbos MH; Janes E; Enblad G; Sautois B; Ullen A; Stenner-Liewen F; Hjalm-Eriksson ME; De Maeseneer DJ; Schatteman P; Ghysel C; Oldenburg J; Lindberg J; Ost P; Eklund M; Gronberg H; De Laere B
  • Journal article: BRITISH JOURNAL OF SURGERY. 2024;111:znae175.055
    Pappas C; Olauson H; Haglund F; Lindberg J; Beergrehn C; Tham E; Sjovall A
  • Article: CLINICAL CANCER RESEARCH. 2024;30(12):2647-2658
    Ofverholm I; Wallander K; Haglund C; Chellappa V; Wejde J; Gellerbring A; Wirta V; Renevey A; Caceres E; Tsagkozis P; Mayrhofer M; Papakonstantinou A; Linder-Stragliotto C; Branstrom R; Larsson O; Lindberg J; Lin Y; de Flon FH
  • Article: NATURE COMMUNICATIONS. 2024;15(1):1828
    Fonseca NM; Maurice-Dror C; Herberts C; Tu W; Fan W; Murtha AJ; Kollmannsberger C; Kwan EM; Parekh K; Schonlau E; Bernales CQ; Donnellan G; Ng SWS; Sumiyoshi T; Vergidis J; Noonan K; Finch DL; Zulfiqar M; Miller S; Parimi S; Lavoie J-M; Hardy E; Soleimani M; Nappi L; Eigl BJ; Kollmannsberger C; Taavitsainen S; Nykter M; Tolmeijer SH; Boerrigter E; Mehra N; van Erp NP; De Laere B; Lindberg J; Gronberg H; Khalaf DJ; Annala M; Chi KN; Wyatt AW
  • Journal article: NATURE MEDICINE. 2024;30(11)
    De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjalm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Thellenberg Karlsson C; Janes E; Sandzen J; Schatteman P; Vigmostad M; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
  • Article: EUROPEAN UROLOGY OPEN SCIENCE. 2023;53:63-66
    Vanwelkenhuyzen J; Van Bos E; Van Bruwaene S; Lesage K; Maes A; Ustmert S; Lavent F; Beels L; Groenberg H; Ost P; Lindberg J; De Laere B
  • Article: CLINICAL CHEMISTRY. 2023;69(4):386-398
    Norgaard M; Bjerre MT; Fredsoe J; Vang S; Jensen JB; De Laere B; Groenberg H; Borre M; Lindberg J; Sorensen KD
  • Article: ANNALS OF ONCOLOGY. 2022;33(8):750-768
    Pascual J; Attard G; Bidard F-C; Curigliano G; De Mattos-Arruda L; Diehn M; Italiano A; Lindberg J; Merker JD; Montagut C; Normanno N; Pantel K; Pentheroudakis G; Popat S; Reis-Filho JS; Tie J; Seoane J; Tarazona N; Yoshino T; Turner NC
  • Article: ELIFE. 2022;11:e71569
    Renaud G; Norgaard M; Lindberg J; Gronberg H; De Laere B; Jensen JB; Borre M; Andersen CL; Sorensen KD; Maretty L; Besenbacher S
  • Article: ISCIENCE. 2022;25(7):104663
    Liu B; Wang Y; Weitz P; Lindberg J; Hartman J; Wang W; Egevad L; Gronberg H; Eklund M; Rantalainen M
  • Article: BIOINFORMATICS. 2022;38(13):3462-3469
    Weitz P; Wang Y; Kartasalo K; Egevad L; Lindberg J; Gronberg H; Eklund M; Rantalainen M
  • Article: PROSTATE. 2022;82(5):576-583
    Lindh C; Samaratunga H; Delahunt B; Bergstrom R; Chellappa V; Yaxley J; Lindberg J; Egevad L
  • Article: NATURE CANCER. 2022;3(2):251-261
    Tamborero D; Dienstmann R; Rachid MH; Boekel J; Lopez-Fernandez A; Jonsson M; Razzak A; Brana I; De Petris L; Yachnin J; Baird RD; Loriot Y; Massard C; Martin-Romano P; Opdam F; Schlenk RF; Vernieri C; Masucci M; Villalobos X; Chavarria E; Balmana J; Apolone G; Caldas C; Bergh J; Ernberg I; Frohling S; Garralda E; Karlsson C; Tabernero J; Voest E; Rodon J; Lehtio J
  • Article: FRONTIERS IN GENETICS. 2022;13:820493
    Deng W; Murugan S; Lindberg J; Chellappa V; Shen X; Pawitan Y; Vu TN
  • Show more

All other publications

  • Corrigendum: NATURE MEDICINE. 2024;30(11):3381
    De Laere B; Crippa A; Discacciati A; Larsson B; Persson M; Johansson S; D'hondt S; Bergstrom R; Chellappa V; Mayrhofer M; Banijamali M; Kotsalaynen A; Schelstraete C; Vanwelkenhuyzen JP; Hjaelm-Eriksson M; Pettersson L; Ullen A; Lumen N; Enblad G; Karlsson CT; Jaenes E; Sandzen J; Schatteman P; Vigmostad MN; Olsson M; Ghysel C; Sautois B; De Roock W; Van Bruwaene S; Anden M; Verbiene I; De Maeseneer D; Everaert E; Darras J; Aksnessether BY; Luyten D; Strijbos M; Mortezavi A; Oldenburg J; Ost P; Eklund M; Gronberg H; Lindberg J
  • Preprint: MEDRXIV. 2024
    Mayrhofer M; Bergström R; Chellappa V; Kotsalaynen A; Murugan S; Crippa A; De Laere B; Urtishak K; Sorensen KD; Garg K; Singh U; Eklund M; Grönberg H; Lindberg J
  • Editorial comment: EUROPEAN UROLOGY FOCUS. 2022;8(6):1617-1621
    De laere B; Crippa A; Discacciati A; Larsson B; Oldenburg J; Mortezavi A; Ost P; Eklund M; Lindberg J; Gronberg H
  • Review: ACTA ONCOLOGICA. 2022;61(4):523-530
    Merk C; Martling A; Lindberg J; Benhaim L; Taieb J; Lind P
  • Review: EUROPEAN UROLOGY FOCUS. 2021;7(4):687-691
    Kartasalo K; Bulten W; Delahunt B; Chen P-HC; Pinckaers H; Olsson H; Ji X; Mulliqi N; Samaratunga H; Tsuzuki T; Lindberg J; Rantalainen M; Wahlby C; Litjens G; Ruusuvuori P; Egevad L; Eklund M
  • Preprint: ARXIV. 2021
    Liu B; Wang Y; Weitz P; Lindberg J; Hartman J; Egevad L; Grönberg H; Eklund M; Rantalainen M
  • Preprint: BIORXIV. 2021
    Renaud G; Nørgaard M; Lindberg J; Grönberg H; De Laere B; Jensen JB; Borre M; Andersen CL; Sørensen KD; Maretty L; Besenbacher S
  • Letter: JOURNAL OF CLINICAL ONCOLOGY. 2019;37(24):2181-2182
    De Laere B; Ost P; Gronberg H; Lindberg J
  • Letter: JAMA ONCOLOGY. 2019;5(7):1060-1062
    De Laere B; Rajan P; Gronberg H; Dirix L; Lindberg J; Mayrhofer M; Whitington T; van Dam P-J; Van Oyen P; Ghysel C; Ampe J; Ost P; Demey W; Hoela L; Schrijvers D; Brouwers B; Lybaert W; Everaert E; De Maeseneer D; Strijbos M; Bols A; Fransis K; Beije N; de Kruijff I; van Dam V; Brouwer A; Goossens D; Heyrman L; Van den Eynden G; Rutten A; Del Favero J; Rantalainen M; Sleijfer S; Ullen A; Yachnin J; Van Laere S; De laere L; Develter T; Vantieghem S; Herman S; Coifs G; Lamotte V; Boumans A; Baitar A; Haeck R; Wallays G
  • Editorial comment: EUROPEAN UROLOGY. 2018;74(6):739-740
    Nordstrom T; Lindberg J; Eklund M
  • Corrigendum: EBIOMEDICINE. 2017;17:238
    Ross-Adams H; Lamb AD; Dunning MJ; Halim S; Lindberg J; Massie CM; Egevad LA; Russell R; Ramos-Montoya A; Vowler SL; Sharma NL; Kay J; Whitaker H; Clarkh J; Hurst R; Gnanapragasam VJ; Shah NC; Warren AY; Cooper CS; Lynch AG; Stark R; Mills IG; Gronberg H; Neal DE
  • Review: GENOMICS. 2010;95(1):1-6
    Lindberg J; Lundeberg J

Grants

  • Liquid biopsies in metastatic prostate cancer
    Swedish prostate cancer foundation
    1 February 2024 - 1 February 2026
  • Swedish Cancer Society
    1 January 2024
  • Liquid biopsies in metastatic prostate cancer
    Radium Hemmets Research Funds
    1 January 2024 - 1 January 2026
  • Detection of inactivating genomic alterations in BRCA1/2 and establishment of a tissue selection algorithm to maximise the probability of successful screening.
    AstraZeneca (Sweden)
    1 January 2024 - 31 December 2026
  • Swedish Research Council
    1 January 2022 - 31 December 2025
  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • Swedish Research Council
    1 January 2021 - 31 December 2024
  • Swedish Cancer Society
    1 January 2021
  • Swedish Research Council
    1 January 2020 - 31 December 2020
  • Swedish Research Council
    1 January 2019 - 31 December 2022
  • Swedish Research Council
    1 January 2018 - 31 December 2020
  • Swedish Research Council
    1 December 2017 - 31 December 2020
  • Swedish Research Council
    1 January 2013 - 31 December 2016
  • Swedish Research Council
    1 January 2010 - 31 December 2012

Employments

  • Principal Researcher, Department of Medical Epidemiology and Biostatistics, ̽»¨¾«Ñ¡, 2022-

Supervision

  • Cecilia Merk, 2022

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