探花精选

Jesper S盲fholm

Jesper S盲fholm

Research Specialist
Visiting address: Nobels v盲g 13, 17177 Stockholm
Postal address: C6 Institutet f枚r milj枚medicin, C6 Integrativ metabolomik Wheelock, 171 77 Stockholm

About me

  • I am currently employed as a Research Specialist in the research environment of the Unit of Integrative Metabolomics. My group consists of supervising two master students, one postdoc and two affilliated scientists. My lab is currently located at Centre for Molecular Medicine (CMM).

     

  •  

  • I initiated my PhD-studies within 

  • the field of airway pharmacology and physiology in 2008 and graduated 2013. This was followed by post graduate work 2014-2018 on mechanisms in asthmatic airway inflammation and I subsequently acquired an assistant professorship for continuation of translational airway pharmacology studies of lipid mediators, airway hyperresponsiveness and inflammation using /in vivo, ex vivo/ and /in vitro/ methods in both animal and human tissue. I am currently a supervisor of three PhD-students in the lab and have successfully supervised Master students during
    their graduation projects. 
  • Between 1999 and 2012 I worked at Astra Zeneca within the departements Safety 
  • Assessment, Neuroscience and Molecular Toxicology as a research technician.

     

  • *Awards*
    * In 2020 I was given the IMM Junior Faculty Strategic Award by The
    Institute of Environmental Medicine, IMM, 探花精选.
    * In 2017 I was awarded the Veritas Pharma Inc. Dom Spina Prize by the
    British Pharmacological Society.
    *Commissions of trust*
    * 2018-2019 I was the organiser of a bi-monthly seminar series within
    physiology and pharmacology at Karolinska Instiutet.
    * 2014-2017 I was board member of Centre for Allergy Research PhD and
    Postdoc Association at Karolinska Instiutet.
    * 2009-2013 I was member of the Educational Board at the Institute of
    Environmental Medicine at Karolinska Instiutet.
    * High School Education (Chemistry), Europaskolan, Str盲ngn盲s, 1998-2001
    * Master of Science in Biology (MSc), Uppsala Universitet, Uppsala,
    2003-2007
    * Doctor of Philosophy (PhD), Institute of Environmental Medicine and
    Experimental Asthma and Allergy Research, 探花精选, Stockholm
    2008-2013

Research

  • Asthma is a major public health concern affecting between 5 and 10% of the
    population. The exacerbations of asthma occur on a background of chronic
    inflammation where inflammatory cells, such as eosinophils and mast cells,
    and their respective mediators, including lipid mediators, orchestrate
    different patterns of inflammation and bronchoconstriction. The purpose of my
    research programme is to define the role of different lipid mediators for
    airway function in relation to the pathobiology of asthma.

Teaching

  • I teach the sections anatomy, physiology, pharmacology, toxicology and pathophysiology of the pulmonary system as well as animal models in pulmonary diseases at two International Master's 

  • Programme (Master's Programme in Toxicology and Master's Programme in Translational Physiology and Pharmacology) at 探花精选. 
  • I also lecture in allergy, airway diseases and inflammation.

     

  • I also teaching visiting researchers, internship students, master students, doctoral students and post-doctoral students in scientific methodology, design of quantitative research, methods for systematic literature review, clinical immunology and allergy, diagnosis and management of asthma and other respiratory diseases, and prevention strategies of allergy and asthma.

Articles

  • Article: ANALYTICAL CHEMISTRY. 2024;96(45):17950-17959
    Smith MJ; Nie M; Adner M; Safholm J; Wheelock CE
  • Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2024;79(12):3464-3474
    Thulin H; Mansouri L; Altman M; Merid SK; Lundahl J; Nilsson C; Safholm J
  • Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2024;78(2):313-319
    Thulin H; Safholm J; Lundahl J; Jovic V; Adner M; Nilsson C
  • Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1393802
    Gong Y; Johnsson A-K; Safholm J; Al-Ameri M; Sachs E; Vali K; Nilsson G; Ronnberg E
  • Article: ONCOIMMUNOLOGY. 2023;12(1):2233402
    Brownlie D; von Kries A; Valenzano G; Wild N; Yilmaz E; Safholm J; Al-Ameri M; Alici E; Ljunggren H-G; Schliemann I; Aricak O; de Flon FH; Michaelsson J; Marquardt N
  • Journal article: AUTHOREA. 2023
    Thulin H; S盲fholm J; Lundahl J; Jovic V; Adner M; Nilsson C
  • Article: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2023;168:106761
    Belikova M; Al-Ameri M; Orre A-C; Safholm J
  • Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1151754
    Ronnberg E; Ravindran A; Mazzurana L; Gong Y; Safholm J; Lorent J; Dethlefsen O; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Dahlin JS; Mjosberg J; Nilsson G
  • Article: SCIENTIFIC REPORTS. 2022;12(1):18924
    Liu J; Nie M; Dong C; Safholm J; Pejler G; Nilsson G; Adner M
  • Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2022;934:175257
    Safholm J; Abma W; Bankova LG; Boyce JA; Al-Ameri M; Orre A-C; Wheelock CE; Dahlen S-E; Adner M
  • Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(9):2677-2687
    Tang X; Ronnberg E; Safholm J; Thulasingam M; Trauelsen M; Schwartz TW; Wheelock CE; Dahlen S-E; Nilsson G; Haeggstrom JZ
  • Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2021;907:174282
    Safholm J; Abma W; Liu J; Balgoma D; Fauland A; Kolmert J; Wheelock CE; Adner M; Dahlen S-E
  • Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2021;1866(5):158886
    Johnsson A-K; Ronnberg E; Fuchs D; Kolmert J; Safholm J; Claesson H-E; Hamberg M; Wheelock CE; Nilsson G; Dahlen S-E
  • Article: CELL RESEARCH. 2021;31(5):554-568
    Mazzurana L; Czarnewski P; Jonsson V; Wigge L; Ringner M; Williams TC; Ravindran A; Bjorklund AK; Safholm J; Nilsson G; Dahlen S-E; Orre A-C; Al-Ameri M; Hoog C; Hedin C; Szczegielniak S; Almer S; Mjosberg J
  • Article: FRONTIERS IN IMMUNOLOGY. 2021;12:804812
    Ronnberg E; Boey DZH; Ravindran A; Safholm J; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Dahlin JS; Nilsson G
  • Article: FRONTIERS IN IMMUNOLOGY. 2021;12:761317
    Che KF; Paulsson M; Piersiala K; Sax J; Mboob I; Rahman M; Rekha RS; Safholm J; Adner M; Bergman P; Cardell L-O; Riesbeck K; Linden A
  • Article: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2020;149:106428
    Abma W; Noreby M; Wheelock CE; Dahlen S-E; Adner M; Safholm J
  • Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(3):808-817.e2
    Manson ML; Safholm J; James A; Johnsson A-K; Bergman P; Al-Ameri M; Orre A-C; Karrman-Mardh C; Dahlen S-E; Adner M
  • Article: CELLS. 2019;8(11):1372
    Tebroke J; Lieverse OE; Saefholm S; Schulte G; Nilsson G; Roennberg E
  • Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):984-992
    Safholm J; Manson ML; Bood J; Al-Ameri M; Orre A-C; Raud J; Dahlen S-E; Adner M
  • Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2019;49(3):285-291
    Ekstedt S; Safholm J; Georen SK; Cardell LO
  • Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1361
    Ronnberg E; Ghaib A; Ceriol C; Enoksson M; Arock M; Safholm J; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Ekoff M; Nilsson G
  • Article: ANALYTICAL CHEMISTRY. 2018;90(17):10239-10248
    Kolmert J; Fauland A; Fuchs D; Safholm J; Gomez C; Adner M; Dahlen S-E; Wheelock CE
  • Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2193
    Ravindran A; Ronnberg E; Dahlin JS; Mazzurana L; Safholm J; Orre A-C; Al-Ameri M; Peachell P; Adner M; Dahlen S-E; Mjosberg J; Nilsson G
  • Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1321-1330.e4
    Marquardt N; Kekalainen E; Chen P; Kvedaraite E; Wilson JN; Ivarsson MA; Mjosberg J; Berglin L; Safholm J; Manson ML; Adner M; Al-Ameri M; Bergman P; Orre A-C; Svensson M; Dahlen B; Dahlen S-E; Ljunggren H-G; Michaelsson J
  • Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;136(5):1232-1239.e1
    Safholm J; Manson ML; Bood J; Delin I; Orre A-C; Bergman P; Al-Ameri M; Dahlen S-E; Adner M
  • Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2014;740:302-311
    Manson ML; Safholm J; Al-Ameri M; Bergman P; Orre A-C; Sward K; James A; Dahlen S-E; Adner M
  • Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;718(1-3):277-282
    Safholm J; Dahlen S-E; Adner M
  • Article: BRITISH JOURNAL OF PHARMACOLOGY. 2013;168(4):794-806
    Safholm J; Dahlen S-E; Delin I; Maxey K; Stark K; Cardell L-O; Adner M
  • Article: AMERICAN JOURNAL OF PHYSIOLOGY - LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;303(11):L956-L966
    Pulkkinen V; Manson ML; Safholm J; Adner M; Dahlen S-E
  • Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2010;333(1):273-280
    Adner M; Larsson B; Safholm J; Naya I; Miller-Larsson A
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All other publications

  • Conference publication: 2024;:pa348
    S盲fholm J; Dahl茅n S-E; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa896
    Xiang Y; Liu J; Nie M; Nilsson G; Safholm J; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa895
    Adner M; Nie M; Liu J; Xiang Y; Nilsson G; Safholm J
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa2185
    Belikova M; Johnsson A-K; Kolmert J; Wheelock CE; Abma W; Al-Ameri M; Dimberg A; Sachs E; Jalali KV; Adner M; Nilsson G; Dahlen S-E; Safholm J
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa2665
    Seren RM; Abma W; Kolmert J; Safholm J; Wheelock CE
  • Preprint: CHEMRXIV. 2024
    Smith M; Nie M; Adner M; S盲fholm J; Wheelock C
  • Letter: CLINICAL AND EXPERIMENTAL ALLERGY. 2023;53(10):1062-1066
    Belikova M; Safholm J; Al-Ameri M; Orre A-C; Dahlen S-E; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa595
    Nie M; Liu J; Safholm J; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa4404
    Liu J; Xiang Y; Nie M; Wong A; Safholm J; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa1303
    Xiang Y; Liu J; Nie M; Safholm J; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa4405
    Safholm J; Dahlen S-E; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:oa4209
    Belikova M; Safholm J; Al-Ameri M; Orre A-C; Dahlen S-E; Adner M
  • Preprint: AUTHOREA. 2023
    Thulin H; S盲fholm J; Lundahl J; Jovic V; Adner M; Nilsson C
  • Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a2809
    Safholm J; Dahlen S; Adner M
  • Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;78:179
    Thulin H; Safholm J; Lundahl J; Jovic V; Adner M; Nilsson C
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:2392
    Liu J; Nie M; Dong C; Safholm J; Pejler G; Nilsson G; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2022;60:2519
    Safholm J; Abma W; Wheelock CE; Dahlen S; Adner M
  • Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;76(7):2270-2273
    Liu J; Kolmert J; Safholm J; Johnsson A-K; Zurita J; Wheelock CE; Dahlen S-E; Nilsson G; Adner M
  • Preprint: AUTHOREA PREPRINTS. 2021
    R枚nnberg E; Hao DBZ; Ravindran A; S盲fholm J; Orre A-C; Al-Ameri M; Adner M; Dahl茅n S-E; Dahlin J; Nilsson G
  • Preprint: BIORXIV. 2021
    R枚nnberg E; Boey DZH; Ravindran A; S盲fholm J; Orre A-C; Al-Ameri M; Adner M; Dahl茅n S-E; Dahlin J; Nilsson G
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2043
    Liu J; Kolmert J; Safholm J; Wheelock CE; Dahlen S-E; Nilsson G; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2897
    Safholm J; Abma W; Liu J; Balgoma D; Kolmert J; Fauland A; Wheelock CE; Adner M; Dahlen S-E
  • Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 2020;177(11):2581-2582
    Abma W; Safholm J; Wheelock C; Dahlen S-E; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa4092
    Ekstedt S; Safholm J; Stenberg H; Tufvesson ET; Diamant Z; Bjermer L; Georen SK; Cardell LO
  • Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 2019;176(16):3021
    Abma W; Safholm J; Wheelock C; Dahlen S; Adner M
  • Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 2019;176(16):3037-3038
    Safholm J; Lee T; Ting H; Wheelock C; Orre A; Bergman P; Al-Ameri M; Adner M; Dahlen S
  • Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74:87
    Hockerlind RE; Dahlin J; Tebroke J; Lieverse J; Ravindran A; Safholm J; Nilsson G
  • Preprint: BIORXIV. 2018
    R枚nnberg E; Ghaib A; Ceriol C; Enoksson M; Arock M; S盲fholm J; Ekoff M; Nilsson G
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1044
    Safholm J; Balgoma D; Fauland A; Gomez C; Kolmert J; Adner M; Wheelock C; Dahlen S-E
  • Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2018;197
    Safholm J; Bood J; Bergman P; Orre A; Al-Ameri M; Dahlen S; Adner M
  • Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):300
    Avinash R; Hockerlind ER; Dahlin J; Bergman P; Orre A-C; Adner M; Safholm J; Dahlen S-E; Peachell P; Mjosberg J; Nilsson G
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2016;48:pa5054
    Safholm J; Bood J; Dahlen S-E; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2016;48:oa1983
    Lazarinis N; Bood J; Gomez C; Kolmert J; Safholm J; Lantz A-S; Henriksson E; Wheelock C; Dahlen S-E; Dahlen B
  • Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:67-68
    Marquardt N; Kekalainen E; Wilson JN; Ivarsson MA; Mjosberg J; Safholm J; Manson ML; Adner M; Al-Ameri M; Bergman P; Orre A-C; Dahlen B; Dahlen S-E; Ljunggren H-G; Michaelsson J
  • Other: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;70(11):1353-1355
    Protudjer JLP; Binnmyr J; Grundstrom J; Manson ML; Marquardt N; Safholm J; Ullemar V
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:oa4465
    Safholm J; Manson M; Bood J; Delin I; Orre A-C; Bergman P; Al-Ameri M; Dahlen S-E; Adner M
  • Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa3603
    Manson M; James A; Safholm J; Al-Ameri M; Bergman P; Orre A-C; Dahlen S-E; Adner M
  • Thesis / dissertation: 2013
    S盲fholm, Jesper
  • Conference publication: 2012;:a6477
    Pulkkinen V; Safholm J; Manson M; Adner M; Dahlen S-EK
  • Review: PULMONARY PHARMACOLOGY AND THERAPEUTICS. 2011;24(4):361-366
    Safholm J; Lovdahl C; Swedin L; Boels PJM; Dahlen S-E; Arner A; Adner M
  • Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2011;183:a6381
    Dahlen S-E; Pulkkinen V; Safholm J; Manson M; Adner M
  • Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2009;179:a6323
    Safholm J; Stark K; Cardell L-O; Dahlen S-E; Adner M
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Grants

  • Swedish Heart-Lung Foundation
    1 January 2021 - 31 December 2023

Employments

  • Research Specialist, Institute of Environmental Medicine, 探花精选, 2022-

Degrees and Education

  • Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, 探花精选, 2013

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