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Jeroen Goos

Jeroen Goos

Assistant Professor
Visiting address: BioClinicum J5:20, Akademiska Str氓ket 1, Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Holmin Goos, 171 77 Stockholm
Part of:

Research

  • The focus of my research group lies with the development of new tools for the
    molecular imaging and treatment of patients with cancer. We use synthetic
    molecules, but also biological compounds, that are labelled with radioactive
    isotopes to specifically target the sites in the body where tumours are
    located. Some of these isotopes can be detected using diagnostic imaging
    devices (e.g. PET), whereas other isotopes are more suited for the delivery
    of therapeutic doses of radioactivity that kill the tumour cells.
    Our first research line aims at developing minimally invasive, nuclear
    treatment strategies for patients that suffer from brain cancer. We are
    using natural peptides and bispecific antibodies that are capable to
    cross the blood-brain barrier (BBB) and then specifically bind to tumour
    tissue.
    In our second research line, we are developing new (radio)chemistry to
    improve current pretargeting strategies. The pretargeting strategy
    attempts to decrease radioactive doses to healthy tissues by injecting the
    targeting vector (e.g. an antibody) and radioactive ligand separately, which
    then ligate within the target tissue. By optimising the chemical and
    physiological properties of both, the radioactive doses to healthy
    tissues can significantly be reduced.
    In our third research line, we use imaging isotopes to track immune cells in
    the human body during immune cell therapy.

Articles

  • Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:108801
    Zafar I; Li K; Zammit J; Palm KP; Davydova M; Varshney M; Lu L; Tran T; Bergstrom T; Swartling FJ; Lewis J; Holmin S; Goos J
  • Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:108673
    Friberger I; Tran T; Lu L; Milton S; Samen E; Goos J; Carlsten M; Holmin S
  • Article: EJNMMI RESEARCH. 2023;13(1):73
    Friberger I; Nilsson JNN; Lu L; Siikanen J; Ardenfors O; Milton S; Samen E; Goos JACM; Carlsten M; Holmin S; Tran TAA
  • Article: MOLECULAR IMAGING AND BIOLOGY. 2021;23(6):952-962
    Friberger I; Jussing E; Han J; Goos JACM; Siikanen J; Kaipe H; Lambert M; Harris RA; Samen E; Carlsten M; Holmin S; Tran TA
  • Article: ONCOIMMUNOLOGY. 2020;9(1):1832761
    Nugteren S; Goos JACM; Delis-van Diemen PM; Simons-Oosterhuis Y; Lindenbergh-Kortleve DJ; van Haaften DH; Sanders J; Meijer GA; Fijneman RJA; Samsom JN
  • Article: POLYMER CHEMISTRY. 2020;11(35):5681-5692
    Leiske MN; Mahmoud AM; Warne NM; Goos JACM; Pascual S; Montembault V; Fontaine L; Davis TP; Whittaker MR; Kempe K
  • Journal article: MACROMOLECULAR RAPID COMMUNICATIONS. 2020;41(11)
    Goos JACM; Davydova M; Lengkeek N; Greguric I; Whittaker MR; Quinn JF; Baell JB; Lewis JS; Davis TP
  • Article: MACROMOLECULAR RAPID COMMUNICATIONS. 2020;41(11):e2000061
    Goos JACM; Davydova M; Lengkeek N; Greguric I; Whittaker MR; Quinn JF; Baell JB; Lewis JS; Davis TP
  • Article: NUCLEAR MEDICINE AND BIOLOGY. 2020;84-85:63-72
    Goos JACM; Davydova M; Dilling TR; Cho A; Cornejo MA; Gupta A; Price WS; Puttick S; Whittaker MR; Quinn JF; Davis TP; Lewis JS
  • Article: THERANOSTICS. 2020;10(2):567-584
    Goos JACM; Cho A; Carter LM; Dilling TR; Davydova M; Mandleywala K; Puttick S; Gupta A; Price WS; Quinn JF; Whittaker MR; Lewis JS; Davis TP
  • Article: JOURNAL OF NUCLEAR MEDICINE. 2019;60(11):1569-1578
    Pereira PMR; Mandleywala K; Ragupathi A; Carter LM; Goos JACM; Janjigian YY; Lewis JS
  • Article: BRITISH JOURNAL OF CANCER. 2016;115(12):1565-1574
    den Uil SH; Coupe VMH; Linnekamp JF; van den Broek E; Goos JACM; Diemen PMD-V; Belt EJT; van Grieken NCT; Scott PM; Vermeulen L; Medema JP; Bril H; Stockmann HBAC; Cormier RT; Meijer GA; Fijneman RJA
  • Journal article: CANCER RESEARCH. 2016;76(14_Supplement):3125
    den Uil SH; Coupe VMH; Linnekamp JF; van den Broek E; Goos JACM; Delis-van Diemen PM; Belt EJT; van Grieken NCT; Scott PM; Vermeulen L; Medema JP; Bril H; Stockmann HBAC; Cormier RT; Meijer GA; Fijneman RJ
  • Article: ONCOTARGET. 2016;7(2):2123-2134
    Goos JACM; Coupe VMH; van de Wiel MA; Diosdado B; Delis-Van Diemen PM; Hiemstra AC; de Cuba EMV; Belien JAM; van Oordt CWM-VDH; Geldof AA; Meijer GA; Hoekstra OS; Fijneman RJA
  • Article: NUCLEAR MEDICINE AND BIOLOGY. 2016;43(1):63-72
    Goos JACM; Verbeek J; Geldof AA; Hiernstra AC; van de Wiel MA; Adamzek KA; Delis-Van Diemen PM; Stroud SG; Bradley DP; Meijer GA; Hoekstra OS; Fijneman RJA; Windhorst AD
  • Article: ANNALS OF SURGERY. 2016;263(1):138-145
    Goos JACM; de Cuba EMV; Coupe VMH; Diosdado B; Delis-Van Diemen PM; Karga C; Belien JAM; van Oordt CWM-VDH; Geldof AA; Meijer GA; Hoekstra OS; Fijneman RJA
  • Article: ONCOTARGET. 2015;6(28):26278-26290
    Lenos K; Goos JACM; Vuist IM; den Uil SH; Delis-van Diemen PM; Belt EJT; Stockmann HBAC; Bril H; de Wit M; Carvalho B; Giblett S; Pritchard CA; Meijer GA; van Kooyk Y; Fijneman RJA; van Vliet SJ
  • Article: BRITISH JOURNAL OF CANCER. 2014;111(4):749-755
    Goos JACM; Hiemstra AC; Coupe VMH; Diosdado B; Kooijman W; Delis-Van Diemen PM; Karga C; Belien JAM; van Oordt CWM-VDH; Geldof AA; Meijer GA; Hoekstra OS; Fijneman RJA
  • Article: ONCOGENE. 2014;33(29):3861-3868
    Than BLN; Goos JACM; Sarver AL; O'Sullivan MG; Rod A; Starr TK; Fijneman RJA; Meijer GA; Zhao L; Zhang Y; Largaespada DA; Scott PM; Cormier RT
  • Article: BRITISH JOURNAL OF CANCER. 2013;109(9):2445-2452
    Goos JACM; Coupe VMH; Diosdado B; Diemen PMD-V; Karga C; Belien JAM; Carvalho B; van den Tol MP; Verheul HMW; Geldof AA; Meijer GA; Hoekstra OS; Fijneman RJA
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All other publications

  • Corrigendum: MOLECULAR IMAGING AND BIOLOGY. 2022;24(3):510
    Friberger I; Jussing E; Han J; Goos JACM; Siikanen J; Kaipe H; Lambert M; Harris RA; Samen E; Carlsten M; Holmin S; Tran TA
  • Book chapter: HANDBOOK OF RADIOPHARMACEUTICALS. 2020;p. 535-570
    Goos JACM; Kein盲nen O; Zeglis BM; Lewis JS
  • Preprint: BIORXIV. 2020
    Oni TE; Bautista C; Merrill JR; Goos JACM; Rivera KD; Miyabayashi K; Biffi G; Garcia L; Plenker D; Patel H; Elyada E; Samaritano M; Yu KH; Pappin DJ; Goggins MG; Hruban RH; Lewis JS; Lyons SK; Yeh JT; Tuveson DA
  • Review: FRONTIERS IN PHARMACOLOGY. 2018;9:831
    Chang D; Lim M; Goos JACM; Qiao R; Ng YY; Mansfeld FM; Jackson M; Davis TP; Kavallaris M
  • Conference publication: CANCER RESEARCH. 2015;75(15_Supplement):3419
    Goos JACM; de Cuba EMV; Coupe VMH; Diosdado B; Delis-van Diemen PM; Karga C; Belien JAM; Menke - Van der Houven van Oordt CW; Geldof AA; Meijer GA; Hoekstra OS; Fijneman RJA
  • Conference publication: CANCER RESEARCH. 2014;74(19_Supplement):2853
    Goos JACM; Hiemstra AC; Coup茅 VMH; Diosdado B; Kooijman W; Diemen PMD-V; Karga C; Beli毛n JAM; Oordt CWM-VDHV; Geldof AA; Meijer GA; Hoekstra OS; Fijneman RJA
  • Conference publication: CANCER RESEARCH. 2014;74(19_Supplement):112
    Verbeek J; Goos JA; Geldof AA; Hiemstra AC; Hoekstra OS; Meijer GA; Stroud S; Bradley D; Fijneman RJ; Windhorst AD

Grants

  • Swedish Research Council
    1 January 2022 - 31 December 2025

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