Jan-Bernd Stukenborg
Senior Lecturer | Docent
E-mail: jan-bernd.stukenborg@ki.se
Telephone: +46852482788
Visiting address: BioMedicum A4, Solnavägen 9, 17165 Solna
Postal address: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Stukenborg, 171 77 Stockholm
About me
- I am working right now as senior lecturer and group leader (NORDFERTIL research lab Stockholm) at the Department of Women’s and Children’s
Health, Childhood Cancer Research Unit, ̽ѡ and University Hospital, Stockholm, Sweden. In addtion to my work as group leader, I am the research coordinator of NORDFERTIL (www.nordfertil.org).
*COURSES AND DEGREES*
2001 - 2005 - Study of Biology, Westphalian Wilhelms University (WWU), Münster Germany
2005 - Diploma-thesis (Master Thesis; Biology), Centre of Reproductive Medicine and Andrology (CeRA), WWU, Münster, Germany & University of
Pittsburgh, USA
2005 - 2009 - Ph.D.-studies (Biology), CeRA, WWU, Münster, Germany
*DOCTORAL DEGREE*
2009 - Biology (Reproductive Biology), Title: “/In vitro/ differentiation of male germ cells.” CeRA, WWU, Münster, Germany; PhD supervision: Prof.
Dr. E. Liebau; Prof. Dr. S. Schlatt
*POSTDOC APPOINTMENTS*
2009 – 2013 - Post-Doc at the Department of Women’s and Children’s Health, Pediatric Endocrinology Unit, ̽ѡ; supervision:
Prof. Dr. Olle Söder
*DOCENT-LEVEL COMPETENCE*
2016 - Docent in Reproductive Biology; ̽ѡ
Research
- *Main research areas: *
* Germ cell differentiation /in vivo/ and /in vitro./
* Fertility preservation techniques in children with gonadal dysfunctions.
* Experiments on /in vitro/ differentiation techniques include novel cell culture approaches with human and animal gonadal cells as well as human
embryonic and human induced pluripotent stem cells (hESCs and hiPSCs).
Teaching
- *Ongoing supervision of a PhD candidate:*
1) Yanhua Cui, ̽ѡ
Title: “Novel strategies to preserve future fertility in boys and .”
Registration: 2018-09-11
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Kirsi Jahnukainen, MD, PhD (̽ѡ, Sweden),
Michael Landreh, PhD (̽ѡ
2) Hajar Ali Mohammed Ba Omar, ̽ѡ
Title: “Effects of haematological and oncological diseases on
spermatogonial stem cell populations in boys.”
Registration: 2018-09-04
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Kirsi Jahnukainen, MD, PhD (̽ѡ, Sweden),
Nikolas Herold, MD (̽ѡ)
3) Yifan Yang, ̽ѡ
Title: “Effects of ̽ѡ treatments of gonadal development in boys and
.”
Registration: 2020-01-15
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Kirsi Jahnukainen, MD, PhD (̽ѡ, Sweden);
Jingtao Guo, PhD (University of Utah, USA)
4) Femke Harteveld, ̽ѡ
Title: “Macrophages and the testicular microenvironment in humans.”
Registration: 2020-10-10
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Kirsi Jahnukainen, MD, PhD (̽ѡ, Sweden);
Susana Chuva de Sousa Lopes, PhD (University of Leiden, The Netherlands)
*Ongoing supervision of a PhD candidate as co-supervisor:*
1) Ieva Masliukaite, University of Amsterdam, The Netherlands
Title: “Propagation of human SSCs”.
Registration: 2015-10-20; main supervisor: Sjoerd Repping, MD, PhD
(University of Amsterdam, The Netherlands), co-supervision: Ans M. M. van
Pelt, PhD (University of Amsterdam, The Netherlands), Jan-Bernd Stukenborg,
PhD (̽ѡ, Sweden).
2) Melanie Poganitsch-Korhonen, University of Helsinki, Finland;
Title: “Male fertility, late morbidity and ageing after childhood cancer”
Registration: 2014-09-24; main supervisor Kirsi Jahnukainen, MD, PhD
(University of Helsinki, Finland), co-supervision: Jan-Bernd Stukenborg, PhD
(̽ѡ, Sweden)
3) Bethel Embiae, ̽ѡ
Title: "Functional characterization and targeting of neuroblastoma cell of
origin"
Registration: 2021-01.20; main supervisor: Ninib Baryawno, PhD (Karolinska
Institutet); co-supervision: John Inge Johnson, PhD (̽ѡ),
Malin Wickström Näsman, PhD (̽ѡ), Jan-Bernd Stukenborg,
PhD (̽ѡ)
*PhD candidates supervised up to the defence of the candidate’s doctoral
thesis:*
1) Magdalena Kurek, ̽ѡ
Title: “Human induced pluripotent stem cells differentiation towards the
male germ cell lineage.”
Registration: 2015-01-19; halftime seminar: 2017-05-31; defence: 2019-10-25
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Olle Söder, MD, PhD (̽ѡ, Sweden), Sarita
Panula, PhD (̽ѡ), Rod Mitchell, MD, PhD (University
Edinburgh, UK)
2) Halima Al-Balushi, ̽ѡ
Title: “In vitro models aiming for fertility preservation.”
Registration: 2014-04-22; halftime seminar: 2016-08-31; defence: 2018-11-16
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Olle Söder, MD, PhD (̽ѡ, Sweden); Outi
Hovatta, MD, PhD (̽ѡ, Sweden); Elisabet Åkesson, MD, PhD
(̽ѡ, Sweden)
3) Joao Pedro Alves Lopes, ̽ѡ
Title: “Novel culture systems to model testicular function and
organization.” Registration: 2015-01-19; halftime seminar: 2017-06-07;
defense: 2018-08-31
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Olle Söder, MD, PhD (̽ѡ, Sweden), Ellen
Goossens, PhD (VUB, Belgium)
4) Mina Nikolova Mincheva, University of Münster, Germany
Title: “Interaction of male gonadal cell types in differentiation cell
culture” Registration: 2015-01-01; defense: 2018-03-15
main supervisor: Stefan Schlatt, PhD (University of Münster, Germany),
co-supervision: Sylvia Kaiser, PhD (University of Münster, Germany),
Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden)
5) Ahmed Reda, ̽ѡ
Title: “Artificial testis to study early gonadal development and germ cell
徱ڴڱԳپپDz.”
Registration: 2012-04-24; halftime seminar: 2014-06-03; defence: 2016-09-30;
main supervisor: Jan-Bernd Stukenborg, PhD (̽ѡ, Sweden);
co-supervision: Olle Söder, MD, PhD (̽ѡ, Sweden); Kirsi
Jahnukainen, MD, PhD (̽ѡ, Sweden & University of Helsinki,
Finland
6) Sarita Panula, ̽ѡ
Title: “Differentiation and charaterization of human iPSC derived germ
cells and the derivation of patient specific iPSC lines for the study of
infertility.” Registration: 2009-11-12; halftime seminar: 2012-09-18;
defence: 2015-06-09; main supervisor: Outi Hovatta, MD, PhD (Karolinska
Institutet, Sweden); co-supervision: Olle Söder, MD, PhD (Karolinska
Institutet, Sweden); Jan-Bernd Stukenborg, PhD (̽ѡ,
Sweden), Renee Reijo Pera (Stanford University, USA)
Articles
- Article: ADVANCED SCIENCE. 2025;:e2410533
- Article: CANCER RESEARCH. 2025;85(6):1015-1034
- Article: REPRODUCTION AND FERTILITY. 2025;6(1):e240116
- Article: BRITISH JOURNAL OF HAEMATOLOGY. 2024;205(1):229-235
- Article: HUMAN REPRODUCTION OPEN. 2024;2024(3):hoae049
- Article: HUMAN REPRODUCTION OPEN. 2024;2024(2):hoae010
- Article: DEVELOPMENTAL CELL. 2023;58(20):2097-2111.e3
- Journal article: HUMAN REPRODUCTION. 2023;38(Supplement_1)
- Article: REPRODUCTION AND FERTILITY. 2023;4(2):RAF-22-0050
- Article: DEVELOPMENTAL CELL. 2022;57(9):1160-1176.e5
- Article: METHODS IN MOLECULAR BIOLOGY. 2022;2490:235-249
- Article: FRONTIERS IN TOXICOLOGY. 2022;4:825734
- Article: BMC BIOLOGY. 2021;19(1):212
- Article: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM. 2021;35(5):101567
- Article: FERTILITY AND STERILITY. 2021;116(3):713-720
- Article: FASEB JOURNAL. 2021;35(5):e21513
- Article: CELL STEM CELL. 2021;28(4):764-778.e4
- Article: CELLS. 2021;10(2):241
- Article: BMC MEDICINE. 2020;18(1):374
- Article: ANNALS OF ONCOLOGY. 2020;31(12):1664-1678
- Article: CANCERS. 2020;12(10):E2830-2830
- Article: MOLECULAR HUMAN REPRODUCTION. 2020;26(6):374-388
- Article: HUMAN REPRODUCTION OPEN. 2020;2020(3):hoaa016
- Article: JOURNAL OF CLINICAL MEDICINE. 2020;9(1):E266-266
- Article: DEVELOPMENTAL BIOLOGY. 2019;456(1):25-30
- Article: REPRODUCTIVE TOXICOLOGY. 2019;90:68-76
- Article: HUMAN REPRODUCTION. 2019;34(11):2297-2310
- Article: ENDOCRINOLOGY. 2019;160(1):133-142
- Article: HUMAN REPRODUCTION. 2018;33(9):1677-1683
- Article: HUMAN REPRODUCTION. 2018;33(4):636-645
- Article: NATURE PROTOCOLS. 2018;13(2):248-259
- Article: MOLECULAR HUMAN REPRODUCTION. 2018;24(2):55-63
- Article: STEM CELLS INTERNATIONAL. 2018;2018:7127042-9
- Article: ANNALS OF BIOMEDICAL ENGINEERING. 2017;45(7):1783-1794
- Article: BIOMATERIALS. 2017;130:76-89
- Article: JOURNAL OF ENDOCRINOLOGY. 2017;232(2):247-257
- Article: STEM CELL REPORTS. 2017;8(1):30-38
- Article: TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS. 2016;107(6):225-242
- Article: MOLECULAR HUMAN REPRODUCTION. 2016;22(9):601-612
- Article: ENDOCRINOLOGY. 2016;157(6):2461-2468
- Article: PLOS ONE. 2016;11(10):e0165268
- Article: HUMAN REPRODUCTION. 2015;30(2):256-267
- Article: PLOS ONE. 2015;10(12):e0144029
- Article: REPRODUCTION. 2014;147(6):875-883
- Article: TISSUE & CELL. 2014;46(1):86-96
- Article: FRONTIERS IN ENDOCRINOLOGY. 2014;5:21
- Journal article: INTERNATIONAL JOURNAL OF CHILD HEALTH AND NUTRITION. 2014;3(2):99-107
- Article: PLOS ONE. 2014;9(8):e103809
- Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2013;372(1-2):96-104
- Journal article: L'ENDOCRINOLOGO. 2013;14(1):45
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2012;97(12):4588-4595
- Article: SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE. 2012;58(6):330-338
- Article: FEBS JOURNAL. 2012;279(24):4589-4597
- Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 2012;35(2):211-213
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;418(3):489-493
- Article: SEXUAL DEVELOPMENT. 2011;5(4):188-196
- Article: SEXUAL DEVELOPMENT. 2010;4(4-5):199-212
- Article: ENDOCRINOLOGY. 2010;151(6):2898-2910
- Journal article: BIOLOGY OF REPRODUCTION. 2009;81(Suppl_1):184
- Article: JOURNAL OF ANDROLOGY. 2008;29(3):312-329
- Article: ENDOCRINOLOGY. 2008;149(4):1736-1747
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All other publications
- Editorial comment: MOLECULAR HUMAN REPRODUCTION. 2024;30(2):gaae009
- Review: NPJ MICROGRAVITY. 2023;9(1):24
- Review: HORMONE RESEARCH IN PAEDIATRICS. 2023;96(2):190-206
- Letter: HAEMATOLOGICA. 2022;107(4):975-979
- Editorial comment: FRONTIERS IN ENDOCRINOLOGY. 2022;13:1027813
- Preprint: BIORXIV. 2021
- Review: ANDROLOGY. 2020;8(4):825-834
- Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(3):E1028-1028
- Review: ECANCERMEDICALSCIENCE. 2020;14:1016
- Review: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(11-12):599-608
- Conference publication: HUMAN REPRODUCTION. 2019;34:47-48
- Review: HUMAN REPRODUCTION UPDATE. 2018;24(2):176-191
- Review: ENDOCRINE CONNECTIONS. 2018;7(2):R69-R87
- Letter: LEUKEMIA. 2017;31(6):1460-1463
- Conference publication: HUMAN REPRODUCTION. 2017;32:40-41
- Conference publication: HUMAN REPRODUCTION. 2017;32:8
- Book chapter: GENETICS OF HUMAN INFERTILITY: MONOGRAPHS IN HUMAN GENETICS. 2017;p. 162-172
- Book chapter: MALE HYPOGONADISM: CONTEMPORARY ENDOCRINOLOGY. 2017;p. 235-256
- Conference publication: HUMAN REPRODUCTION. 2017;32:8-9
- Review: FERTILITY AND STERILITY. 2016;106(7):1652-1657.e2
- Conference publication: BONE MARROW TRANSPLANTATION. 2016;51:S453
- Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2016;86:257
- Review: CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY. 2015;22(3):217-223
- Conference publication: HUMAN REPRODUCTION. 2015;30:327
- Review: ASIAN JOURNAL OF ANDROLOGY. 2014;16(1):50-59
- Review: HORMONE RESEARCH IN PAEDIATRICS. 2014;81(1):2-12
- Review: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2012;97(12):4341-4351
- Other: ASIAN JOURNAL OF ANDROLOGY. 2012;14(5):796
- Conference publication: INTERNATIONAL JOURNAL OF ANDROLOGY. 2010;33:81
- Review: MOLECULAR HUMAN REPRODUCTION. 2009;15(9):521-529
- Conference publication: BIOLOGY OF REPRODUCTION. 2009;:89-90
- Other: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2006;257-258:1-5
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Grants
- Swedish Research Council1 January 2022 - 31 December 2024
- Swedish Research Council1 January 2019 - 31 December 2021
- Deutsche Forschungsgemeinschaft1 January 2010 - 31 December 2013
Employments
- Senior Lecturer, Department of Women's and Children's Health, ̽ѡ, 2021-
Degrees and Education
- Docent, ̽ѡ, 2016