Jacob Hollenberg
About me
Professor of Cardiology specialising in Intensive Care
Head of Centre for Resuscitation Science (Karolinska Instiutet)
Senior Consultant, Cardiology, Internal Medicine, Intensive Care (Södersjukhuset)
Research
As the director of the Center for Resuscitation Science at at ̽»¨¾«Ñ¡, I am responsible for a number of clinical studies that aim to improve the care of cardiac arrest patients.
For 20 years, our research group has been studying new methods and data on patients suffering from cardiac arrest. Several of our previous studies have been published in journals such as the New England Journal of Medicine, JAMA, Circulation, European Heart Journal and Intensive Care Medicine. We are also proud that some of our research has had a direct impact on treatment guidelines around the world, such as our studies on fire department and police dispatch in the event of cardiac arrest, simplified CPR, SMS lifesaving and hypothermia treatment. On a personal level, this becomes very concrete when patients who are admitted to the hospital after cardiac arrest and who I treat in my clinical role as a physician at MIVA (̽»¨¾«Ñ¡ intensive care unit) at Södersjukhuset have had the chance to receive new treatments methods that we have previously developed and studied in our research.
The very poor prognosis is one of the strongest driving forces for me and the goal of the research program is to increase survival after sudden cardiac arrest. I have the great privilege of leading a research group with 25-30 extremely talented researchers, doctors, nurses and statisticians. The group also includes colleagues from all over Sweden and we conduct several national and international studies and collaborations.
Our current research program consists of about 10 comprehensive projects that include the entire treatment chain from the home to the ambulance and on to the hospital's emergency and intensive care units. In the research, we originate from clinical knowledge gaps and investigate whether new technology and innovation can improve the chance of survival but also whether established treatments can be applied to new areas of use.
We conduct studies where we evaluate, among other things, whether a new world-unique custom-built defibrillator drone and SMS lifesaving can shorten the time to defibrillation and affect survival. We also study whether a simplified cardiopulmonary resuscitation method with only chest compressions is as good as traditional cardiopulmonary resuscitation, whether cooling of cardiac arrest patients' brains can improve survival, whether new drugs for cardiac arrest are effective, whether ECMO treatment can save lives in cardiac arrest and if artificial intelligence can increase the recognition of cardiac arrest at the alarm center.
Cardiac arrest outside hospitals affects 10, 000 Swedes annually. Today, only 1 in 10 survive. The overall purpose of our research is to make more people survive.
In addition to my role as a researcher, I work as a senior consultant in cardiology and intensive care at the Medical Intensive Care Unit at Södersjukhuset and work as the scientific chair of the Swedish CPR Council.
Articles
- Journal article: RESUSCITATION PLUS. 2024;20:100752
- Article: RESUSCITATION PLUS. 2024;20:100752
- Article: RESUSCITATION. 2024;203:110390
- Article: JAMA NETWORK OPEN. 2024;7(10):e2439196
- Article: RESUSCITATION. 2024;202:110312
- Journal article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2024;32(1):74
- Article: RESUSCITATION PLUS. 2024;18:100596
- Article: RESUSCITATION PLUS. 2024;18:100645
- Article: AMERICAN HEART JOURNAL. 2024;271:97-108
- Article: INTENSIVE CARE MEDICINE. 2024;50(5):678-686
- Journal article: EUROPEAN HEART JOURNAL: CASE REPORTS. 2024;8(4):ytae133
- Article: RESUSCITATION PLUS. 2024;17:100542
- Article: CIRCULATION: CARDIOVASCULAR QUALITY AND OUTCOMES. 2024;17(3):e010027
- Article: THE LANCET: DIGITAL HEALTH. 2023;5(12):e862-e871
- Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(23):7288
- Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2023;12(21):e030456
- Journal article: RESUSCITATION. 2023;192:s120
- Journal article: RESUSCITATION. 2023;192:s52
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2023;67(10):1383-1394
- Article: RESUSCITATION. 2023;193:110012
- Article: THROMBOSIS JOURNAL. 2023;21(1):101
- Article: RESUSCITATION. 2023;191:109921
- Article: RESUSCITATION. 2023;189:109896
- Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2023;82(3):200-210
- Article: EUROPEAN HEART JOURNAL OPEN. 2023;3(4):oead066
- Article: INTENSIVE CARE MEDICINE. 2023;49(7):820-830
- Article: ANNALS OF INTENSIVE CARE. 2023;13(1):31
- Article: CRITICAL CARE. 2023;27(1):86
- Article: ANNALS OF INTENSIVE CARE. 2023;13(1):12
- Article: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2023;12(2):87-95
- Article: JAMA CARDIOLOGY. 2023;8(1):81-88
- Article: EUROPEAN HEART JOURNAL. 2022;43(46):4817-4829
- Article: JOURNAL OF CLINICAL MEDICINE. 2022;11(21):6370
- Article: CRITICAL CARE. 2022;26(1):323
- Article: BRAIN SCIENCES. 2022;12(10):1374
- Article: INTENSIVE CARE MEDICINE. 2022;48(8):1024-1038
- Article: SCIENTIFIC REPORTS. 2022;12(1):12133
- Article: ANNALS OF INTENSIVE CARE. 2022;12(1):62
- Article: RESUSCITATION PLUS. 2022;10:100245
- Article: TRANSFUSION. 2022;62(6):1188-1198
- Article: JOURNAL OF CLINICAL MEDICINE. 2022;11(9):2621
- Article: EUROPEAN HEART JOURNAL. 2022;43(15):1478-1487
- Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2022;30(1):22
- Article: BMJ OPEN. 2022;12(3):e058001
- Article: RESUSCITATION PLUS. 2022;9:100190
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2022;66(3):365-374
- Article: RESUSCITATION. 2022;170:352-360
- Article: CIRCULATION. 2021;144(24):1915-1925
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2021;326(18):1807-1817
- Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.0656
- Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2021;29(1):88
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2021;384(24):2283-2294
- Article: CRITICAL CARE. 2021;25(1):198
- Article: RESUSCITATION. 2021;163:136-145
- Article: RESUSCITATION. 2021;162:11-19
- Article: RESUSCITATION. 2021;162:218-226
- Article: EUROPEAN HEART JOURNAL. 2021;42(11):1094-1106
- Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2020;76(25):2926-2936
- Article: RESUSCITATION. 2020;157:195-201
- Article: CRITICAL CARE. 2020;24(1):653
- Article: RESUSCITATION. 2020;156:196-201
- Article: HEART. 2020;106(14):1087-1093
- Article: INTENSIVE CARE MEDICINE. 2020;46(7):1361-1370
- Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2020;28(1):60
- Article: RESUSCITATION. 2020;151:67-74
- Article: INTERNATIONAL JOURNAL OF CARDIOLOGY: HEART & VASCULATURE. 2020;27:100483
- Article: BMJ OPEN. 2019;9(11):e030895
- Article: RESUSCITATION. 2019;143:142-147
- Journal article: RESUSCITATION. 2019;142:e13
- Article: CIRCULATION. 2019;139(23):2600-2609
- Article: RESUSCITATION. 2019;139:253-261
- Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2019;321(17):1677-1685
- Article: BMJ OPEN. 2019;9(5):e025531
- Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2019;27(1):40
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2019;63(4):500-505
- Article: HEART. 2019;105(8):632-638
- Article: ENVIRONMENTAL POLLUTION. 2019;245:1-8
- Article: DATA IN BRIEF. 2018;21:1541-1551
- Article: RESUSCITATION. 2018;133:118-123
- Article: HEART. 2018;104(23):1929-1936
- Article: RESUSCITATION. 2018;130:73-80
- Article: BMJ OPEN. 2018;8(6):e022092
- Article: AIR MEDICAL JOURNAL. 2018;37(3):170-173
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2017;61(10):1296-1304
- Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2017;6(10):e005873
- Article: BMJ OPEN. 2017;7(5):e014801
- Article: RESUSCITATION. 2017;115:141-147
- Article: RESUSCITATION. 2017;114:152-156
- Article: RESUSCITATION. 2017;113:33-38
- Journal article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2017;25(Suppl 1):16
- Article: RESUSCITATION. 2017;110:48-55
- Journal article: CIRCULATION. 2016;134(suppl_1)
- Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2016;24(1):124
- Article: RESUSCITATION. 2016;107:129-134
- Article: INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH. 2016;219(4-5):389-397
- Journal article: RESUSCITATION. 2015;96:45
- Journal article: RESUSCITATION. 2015;96:17
- Article: PEDIATRIC CRITICAL CARE MEDICINE. 2015;16(8):750-757
- Article: RESUSCITATION. 2015;94:28-32
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2015;372(24):2307-2315
- Article: NEW ENGLAND JOURNAL OF MEDICINE. 2015;372(24):2316-2325
- Article: RESUSCITATION. 2015;91:1-7
- Article: RESUSCITATION. 2015;90:143-149
- Article: EUROPEAN HEART JOURNAL: ACUTE CARDIOVASCULAR CARE. 2014;3(4):293-303
- Article: EUROPEAN HEART JOURNAL. 2014;35(13):861-867
- Journal article: INTERNATIONAL JOURNAL OF CLINICAL MEDICINE. 2014;2014(02):81-86
- Journal article: CIRCULATION. 2013;128(suppl_22)
- Article: BMC EMERGENCY MEDICINE. 2013;13:21
- Journal article: CIRCULATION. 2012;126(suppl_21)
- Journal article: RESUSCITATION. 2012;83:e56
- Journal article: RESUSCITATION. 2012;83:e21
- Journal article: RESUSCITATION. 2012;83:e52-e53
- Article: RESUSCITATION. 2012;83(10):1253-1258
- Article: RESUSCITATION. 2011;82(12):1514-1518
- Journal article: CIRCULATION. 2011;124(suppl_21)
- Article: HEART. 2011;97(17):1391-1396
- Journal article: RESUSCITATION. 2010;81(2):s94
- Journal article: RESUSCITATION. 2010;81(2):s88
- Article: EUROPEAN JOURNAL OF HEALTH ECONOMICS. 2010;13(6):811-818
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2010;54(5):649-652
- Article: LAKARTIDNINGEN. 2010;107(8):502-505
- Journal article: EUROPEAN HEART JOURNAL. 2010;31(3):378-379
- Article: RESUSCITATION. 2009;80(9):1025-1028
- Article: EUROPEAN HEART JOURNAL. 2009;30(14):1781-1789
- Article: SCANDINAVIAN JOURNAL OF TRAUMA, RESUSCITATION AND EMERGENCY MEDICINE. 2009;17:18
- Article: RESUSCITATION. 2009;80(3):329-333
- Journal article: ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX - PRATIQUE. 2008;2008(171):37
- Article: CIRCULATION. 2008;118(4):389-396
- Article: CIRCULATION. 2007;116(25):2908-2912
- Article: EUROPEAN JOURNAL OF EMERGENCY MEDICINE. 2007;14(5):256-259
- Article: RESUSCITATION. 2007;74(2):242-252
- Journal article: EUROPEAN JOURNAL OF EMERGENCY MEDICINE. 2006;13(5):a5-a6
- Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2005;3(8):777-783
- Article: JOURNAL OF INTERNAL MEDICINE. 2005;257(3):247-254
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All other publications
- Other: EUROPEAN HEART JOURNAL: CASE REPORTS. 2024;8(4):ytae133
- Conference publication: CIRCULATION. 2023;148(Suppl_1):a151
- Conference publication: RESUSCITATION. 2023;192:s142
- Conference publication: RESUSCITATION. 2023;192:s145
- Conference publication: RESUSCITATION. 2023;192:s162
- Conference publication: RESUSCITATION. 2023;192:s153-S154
- Preprint: RESEARCH SQUARE. 2023
- Conference publication: CIRCULATION. 2022;146(Suppl_1):a293
- Corrigendum: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2022;327(3):286
- Preprint: SSRN. 2022
- Conference publication: EUROPEAN HEART JOURNAL. 2021;42:1503
- Preprint: MEDRXIV. 2021
- Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(1):57-72
- Conference publication: EUROPEAN HEART JOURNAL. 2021;42:656
- Preprint: SSRN ELECTRONIC JOURNAL. 2021
- Preprint: MEDRXIV. 2020
- Corrigendum: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2020;64(1):139
- Preprint: SSRN ELECTRONIC JOURNAL. 2020
- Conference publication: CIRCULATION. 2019;140(Suppl_2)
- Conference publication: EUROPEAN HEART JOURNAL. 2019;40(Supplement_1):ehz745.0741
- Conference publication: RESUSCITATION. 2019;142:e20
- Conference publication: EUROPEAN HEART JOURNAL. 2019;40:2523
- Review: JOURNAL OF INTERNAL MEDICINE. 2018;283(3):238-256
- Letter: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2017;317(22):2332-2334
- Conference publication: BMJ OPEN. 2017;7(Suppl 3):a4
- Conference publication: 2017;:a3.1-a3a3
- Review: EUROPEAN HEART JOURNAL (EHJ) - CARDIOVASCULAR PHARMACOTHERAPY. 2016;2(1):54-75
- Conference publication: RESUSCITATION. 2015;96:125
- Conference publication: RESUSCITATION. 2015;96:2
- Conference publication: RESUSCITATION. 2015;96:26-27
- Conference publication: RESUSCITATION. 2015;96:21
- Conference publication: ISEE CONFERENCE ABSTRACTS. 2015;2015(1)
- Review: LAKARTIDNINGEN. 2015;112:C7E6
- Review: LAKARTIDNINGEN. 2015;112:C6CS
- Review: LAKARTIDNINGEN. 2015;112:CZ4R
- Conference publication: CIRCULATION. 2013;128(suppl_22)
- Conference publication: CIRCULATION. 2013;128(suppl_22)
- Conference publication: ISEE CONFERENCE ABSTRACTS. 2013;2013(1)
- Review: JOURNAL OF INTERNAL MEDICINE. 2013;273(6):572-583
- Letter: LAKARTIDNINGEN. 2013;110(19-20):959
- Conference publication: CIRCULATION. 2013;128(22)
- Conference publication: CIRCULATION. 2013;128(22)
- Conference publication: CIRCULATION. 2013;128(22)
- Conference publication: CIRCULATION. 2011;124(21)
- Letter: EUROPEAN HEART JOURNAL. 2010;31(3):378-379
- Thesis / dissertation: 2008
- Conference publication: EUROPEAN HEART JOURNAL. 2008;29:396-397
- Conference publication: EUROPEAN HEART JOURNAL. 2007;28:37-38
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Grants
- Swedish Research Council1 January 2024 - 31 December 2027
- Swedish Heart-Lung Foundation1 January 2020 - 31 December 2022
- Swedish Heart-Lung Foundation1 January 2020 - 31 December 2022
- Swedish Heart-Lung Foundation1 January 2020 - 31 December 2021
- Swedish Heart-Lung Foundation1 January 2020 - 31 December 2020
- Swedish Heart-Lung Foundation1 January 2019 - 31 December 2020
- Swedish Heart-Lung Foundation1 January 2019 - 31 December 2021
- Swedish Research Council1 January 2018 - 31 December 2020
- Swedish Research Council1 January 2018 - 31 December 2021
Employments
- Professor/Senior Physician, Department of Clinical Science and Education, Södersjukhuset, ̽»¨¾«Ñ¡, 2022-
Degrees and Education
- Docent, ̽»¨¾«Ñ¡, 2015
- Doctor Of Philosophy, Department of Clinical Science and Education, Södersjukhuset, ̽»¨¾«Ñ¡, 2008
- University Medical Degree, ̽»¨¾«Ñ¡, 2003