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Felix Grassmann

Felix Grassmann

Affiliated to Research
Visiting address: Nobels väg 12a, 17165 Solna
Postal address: C8 Medicinsk epidemiologi och biostatistik, C8 MEB Czene, 171 77 Stockholm
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About me

  • I am a Researcher at the Department of Medical Epidemiology and
    Biostatistics. My research focuses on the genetic architecture of risk and
    prognosis of inherited diseases.

Research

  • The main aspect of my research is to understand the genetic architecture of
    inherited diseases and how genetics influences disease severity and
    progression. While it is important to identify the precise genetic mechanism
    and pathway underlying disease risk and to shed light on the missing
    heritability, this knowledge alone will not be sufficient to effectively
    eliminate the burden of genetically determined diseases. Therefore, my
    research aims to understand the involvement of genetic factors in the
    consequence of diseases, particularly for diseases with limited or without
    treatment options since understanding the genetics of disease severity and
    progression is a potent method to identify novel targets for treatment. In
    addition, I am interested in understanding how diseases are genetically
    related in order to shed further light on the underlying genetic architecture
    and to potentially identify novel treatment options, since a shared genetic
    basis can point to shared treatment opportunities. Finally, my research
    focuses on alternative and less explored genetic markers such as somatic
    mosaicism of sex chromosomes, which are currently emerging as an important
    marker for both risk and severity of diseases and may have important
    implications for risk prediction and disease management.

Articles

  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2024;116(6):911-919
    Xiao Q; Mao X; Ploner A; Grassmann F; Rodriguez J; Eriksson M; Hall P; Czene K
  • Journal article: CELL METABOLISM. 2024;36(5):1076-1087.e4
    Leeson-Payne A; Iyinikkel J; Malcolm C; Lam BYH; Sommer N; Dowsett GKC; de Morentin PBM; Thompson D; Mackenzie A; Chianese R; Kentistou K; Gardner EJ; Perry JRB; Grassmann F; Speakman JR; Rochford JJ; Yeo GSH; Murray F; Heisler LK
  • Article: BRITISH JOURNAL OF CANCER. 2024;130(4):620-627
    Grassmann F; Maelarstig A; Dahl L; Bendes A; Dale M; Thomas CE; Gabrielsson M; Hedman AK; Eriksson M; Margolin S; Huang T-H; Ulfstedt M; Forsberg S; Eriksson P; Johansson M; Hall P; Schwenk JM; Czene K
  • Journal article: MOLECULAR PSYCHIATRY. 2024;29(3):660-670
    McEwan AR; Hing B; Erickson JC; Hutchings G; Urama C; Norton-Hughes E; D'Ippolito M; Berry S; Delibegovic M; Grassmann F; MacKenzie A
  • Article: JAMA ONCOLOGY. 2024;10(3):372-379
    Rodriguez J; Grassmann F; Xiao Q; Eriksson M; Mao X; Bajalica-Lagercrantz S; Hall P; Czene K
  • Journal article: JOURNAL OF NEUROINFLAMMATION. 2024;21(1):33
    Pfaller AM; Kaplan L; Carido M; Grassmann F; Diaz-Lezama N; Ghaseminejad F; Wunderlich KA; Glaenzer S; Bludau O; Pannicke T; Weber BHF; Koch SF; Bonev B; Hauck SM; Grosche A
  • Article: NATURE COMMUNICATIONS. 2023;14(1):7680
    Malarstig A; Grassmann F; Dahl L; Dimitriou M; McLeod D; Gabrielson M; Smith-Byrne K; Thomas CE; Huang T-H; Forsberg SKG; Eriksson P; Ulfstedt M; Johansson M; Sokolov AV; Schioth HB; Hall P; Schwenk JM; Czene K; Hedman AK
  • Journal article: TRIALS. 2023;24(1):718
    Schmitz D; Thielemann L; Grassmann F
  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2023;115(11):1310-1317
    Mao X; He W; Eriksson M; Lindstroem LS; Holowko N; Bajalica-Lagercrantz S; Hammarstrom M; Grassmann F; Humphreys K; Easton D; Hall P; Czene K
  • Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2023;115(9):1020-1028
    Wang Q-L; Zhang Y; Zeng E; Grassmann F; He W; Czene K
  • Article: BREAST CANCER RESEARCH. 2023;25(1):93
    Middha PK; Wang X; Behrens S; Bolla MK; Wang Q; Dennis J; Michailidou K; Ahearn TU; Andrulis IL; Anton-Culver H; Arndt V; Aronson KJ; Auer PL; Augustinsson A; Baert T; Freeman LEB; Becher H; Beckmann MW; Benitez J; Bojesen SE; Brauch H; Brenner H; Brooks-Wilson A; Campa D; Canzian F; Carracedo A; Castelao JE; Chanock SJ; Chenevix-Trench G; Cordina-Duverger E; Couch FJ; Cox A; Cross SS; Czene K; Dossus L; Dugue P-A; Eliassen AH; Eriksson M; Evans DG; Fasching PA; Figueroa J; Fletcher O; Flyger H; Gabrielson M; Gago-Dominguez M; Giles GG; Gonzalez-Neira A; Grassmann F; Grundy A; Guenel P; Haiman CA; Hakansson N; Hall P; Hamann U; Hankinson SE; Harkness EF; Holleczek B; Hoppe R; Hopper JL; Houlston RS; Howell A; Hunter DJ; Ingvar C; Isaksson K; Jernstroem H; John EM; Jones ME; Kaaks R; Keeman R; Kitahara CM; Ko Y-D; Koutros S; Kurian AW; Lacey JV; Lambrechts D; Larson NL; Larsson S; Le Marchand L; Lejbkowicz F; Li S; Linet M; Lissowska J; Martinez ME; Maurer T; Mulligan AM; Mulot C; Murphy RA; Newman WG; Nielsen SF; Nordestgaard BG; Norman A; O'Brien KM; Olson JE; Patel AV; Prentice R; Rees-Punia E; Rennert G; Rhenius V; Ruddy KJ; Sandler DP; Scott CG; Shah MT; Shu X-O; Smeets A; Southey MC; Stone J; Tamimi RM; Taylor JA; Teras LR; Tomczyk K; Troester MA; Truong T; Vachon CM; Wang SS; Weinberg CR; Wildiers H; Willett W; Winham SJ; Wolk A; Yang X; Zamora MP; Zheng W; Ziogas A; Dunning AM; Pharoah PDP; Garcia-Closas M; Schmidt MK; Kraft P; Milne RL; Lindstroem S; Easton DF; Chang-Claude J
  • Article: CANCER MEDICINE. 2023;12(15):16142-16162
    Morra A; Schreurs MAC; Andrulis IL; Anton-Culver H; Augustinsson A; Beckmann MW; Behrens S; Bojesen SE; Bolla MK; Brauch H; Broeks A; Buys SS; Camp NJ; Castelao JE; Cessna MH; Chang-Claude J; Chung WK; Colonna SV; Couch FJ; Cox A; Cross SS; Czene K; Daly MB; Dennis J; Devilee P; Doerk T; Dunning AM; Dwek M; Easton DF; Eccles DM; Eriksson M; Evans DG; Fasching PA; Fehm TN; Figueroa JD; Flyger H; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Garcia-Saenz JA; Genkinger JA; Grassmann F; Guendert M; Hahnen E; Haiman C; Hamann U; Harrington PA; Hartikainen JM; Hoppe R; Hopper JL; Houlston RS; Howell A; Jakubowska A; Janni W; Jernstroem H; John EM; Johnson N; Jones ME; Kristensen VN; Kurian AW; Lambrechts D; Le Marchand L; Lindblom A; Lubinski J; Lux MP; Mannermaa A; Mavroudis D; Mulligan AM; Muranen TA; Nevanlinna H; Nevelsteen I; Neven P; Newman WG; Obi N; Offit K; Olshan AF; Park-Simon T-W; Patel AV; Peterlongo P; Phillips K-A; Plaseska-Karanfilska D; Polley EC; Presneau N; Pylkas K; Rack B; Radice P; Rashid MU; Rhenius V; Robson M; Romero A; Saloustros E; Sawyer EJ; Schmutzler RK; Schuetze S; Scott C; Shah MT; Smichkoska S; Southey MC; Tapper WJ; Teras LR; Tollenaar RAEM; Tomczyk K; Tomlinson I; Troester M; Vachon C; van Veen E; Wang Q; Wendt C; Wildiers H; Winqvist RA; Ziogas A; Hall P; Pharoah PDP; Adank M; Hollestelle A; Schmidt MK; Hooning MJ
  • Article: CANCERS. 2023;15(13):3313
    Figlioli G; Billaud A; Wang Q; Bolla MK; Dennis J; Lush M; Kvist A; Adank MA; Ahearn TU; Antonenkova NN; Auvinen P; Behrens S; Bermisheva M; Bogdanova NV; Bojesen SE; Bonanni B; Bruening T; Camp NJ; Campbell A; Castelao JE; Cessna MH; Czene K; Devilee P; Doerk T; Eriksson M; Fasching PA; Flyger H; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Glendon G; Garcia EG; Gonzalez-Neira A; Grassmann F; Guenel P; Hahnen E; Hamann U; Hillemanns P; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jakubowska A; Khusnutdinova EK; Kristensen VN; Lindblom A; Loizidou MA; Lubinski J; Mannermaa A; Maurer T; Mavroudis D; Newman WG; Obi N; Panayiotidis MI; Radice P; Rashid MU; Rhenius V; Ruebner M; Saloustros E; Sawyer EJ; Schmidt MK; Schmutzler RK; Shah MT; Southey MC; Tomlinson I; Truong T; van Veen EM; Wendt C; Yang XR; Michailidou K; Dunning AM; Pharoah PDP; Easton DF; Andrulis IL; Evans DG; Hollestelle A; Chang-Claude J; Milne RL; Peterlongo P
  • Journal article: TRIALS. 2023;24(1):407
    Schmitz D; Thielemann L; Grassmann F
  • Article: CARDIOVASCULAR RESEARCH. 2023;119(4):998-1007
    Luo J; Noordam R; Jukema JW; van Dijk KW; Hagg S; Grassmann F; le Cessie S; van Heemst D
  • Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2023;31(5):578-587
    Figlioli G; Billaud A; Ahearn TU; Antonenkova NN; Becher H; Beckmann MW; Behrens S; Benitez J; Bermisheva M; Blok MJ; Bogdanova NV; Bonanni B; Burwinkel B; Camp NJ; Campbell A; Castelao JE; Cessna MH; Chanock SJ; Czene K; Devilee P; Doerk T; Engel C; Eriksson M; Fasching PA; Figueroa JD; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Gonzalez-Neira A; Grassmann F; Guenel P; Guendert M; Hadjisavvas A; Hahnen E; Hall P; Hamann U; Harrington PA; He W; Hillemanns P; Hollestelle A; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jager A; Jakubowska A; Khusnutdinova EK; Ko Y-D; Kristensen VN; Lindblom A; Lissowska J; Lubinski J; Mannermaa A; Manoukian S; Margolin S; Mavroudis D; Newman WG; Obi N; Panayiotidis MI; Rashid MU; Rhenius V; Rookus MA; Saloustros E; Sawyer EJ; Schmutzler RK; Shah M; Sironen R; Southey MC; Suvanto M; Tollenaar RAEM; Tomlinson I; Truong T; van der Kolk LE; van Veen EM; Wappenschmidt B; Yang XR; Bolla MK; Dennis J; Dunning AM; Easton DF; Lush M; Michailidou K; Pharoah PDP; Wang Q; Adank MA; Schmidt MK; Andrulis IL; Chang-Claude J; Nevanlinna H; Chenevix-Trench G; Evans DG; Milne RL; Radice P; Peterlongo P
  • Article: GENOME MEDICINE. 2023;15(1):7
    Mueller SH; Lai AG; Valkovskaya M; Michailidou K; Bolla MK; Wang Q; Dennis J; Lush M; Abu-Ful Z; Ahearn TU; Andrulis IL; Anton-Culver H; Antonenkova NN; Arndt V; Aronson KJ; Augustinsson A; Baert T; Freeman LEB; Beckmann MW; Behrens S; Benitez J; Bermisheva M; Blomqvist C; Bogdanova NV; Bojesen SE; Bonanni B; Brenner H; Brucker SY; Buys SS; Castelao JE; Chan TL; Chang-Claude J; Chanock SJ; Choi J-Y; Chung WK; Colonna SV; Cornelissen S; Couch FJ; Czene K; Daly MB; Devilee P; Dork T; Dossus L; Dwek M; Eccles DM; Ekici AB; Eliassen AH; Engel C; Evans DG; Fasching PA; Fletcher O; Flyger H; Gago-Dominguez M; Gao Y-T; Garcia-Closas M; Garcia-Saenz JA; Genkinger J; Gentry-Maharaj A; Grassmann F; Guenel P; Gundert M; Haeberle L; Hahnen E; Haiman CA; Hakansson N; Hall P; Harkness EF; Harrington PA; Hartikainen JM; Hartman M; Hein A; Ho W-K; Hooning MJ; Hoppe R; Hopper JL; Houlston RS; Howell A; Hunter DJ; Huo D; Investigators A; Ito H; Iwasaki M; Jakubowska A; Janni W; John EM; Jones ME; Jung A; Kaaks R; Kang D; Khusnutdinova EK; Kim S-W; Kitahara CM; Koutros S; Kraft P; Kristensen VN; Kubelka-Sabit K; Kurian AW; Kwong A; Lacey JV; Lambrechts D; Le Marchand L; Li J; Linet M; Lo W-Y; Long J; Lophatananon A; Mannermaa A; Manoochehri M; Margolin S; Matsuo K; Mavroudis D; Menon U; Muir K; Murphy RA; Nevanlinna H; Newman WG; Niederacher D; O'Brien KM; Obi N; Offit K; Olopade OI; Olshan AF; Olsson H; Park SK; Patel AV; Patel A; Perou CM; Peto J; Pharoah PDP; Plaseska-Karanfilska D; Presneau N; Rack B; Radice P; Ramachandran D; Rashid MU; Rennert G; Romero A; Ruddy KJ; Ruebner M; Saloustros E; Sandler DP; Sawyer EJ; Schmidt MK; Schmutzler RK; Schneider MO; Scott C; Shah M; Sharma P; Shen C-Y; Shu X-O; Simard J; Surowy H; Tamimi RM; Tapper WJ; Taylor JA; Teo SH; Teras LR; Toland AE; Tollenaar RAEM; Torres D; Torres-Mejia G; Troester MA; Truong T; Vachon CM; Vijai J; Weinberg CR; Wendt C; Winqvist R; Wolk A; Wu AH; Yamaji T; Yang XR; Yu J-C; Zheng W; Ziogas A; Ziv E; Dunning AM; Easton DF; Hemingway H; Hamann U; Kuchenbaecker KB
  • Journal article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2023;31(5):578-587
    Figlioli G; Billaud A; Ahearn TU; Antonenkova NN; Becher H; Beckmann MW; Behrens S; Benitez J; Bermisheva M; Blok MJ; Bogdanova NV; Bonanni B; Burwinkel B; Camp NJ; Campbell A; Castelao JE; Cessna MH; Chanock SJ; Czene K; Devilee P; Doerk T; Engel C; Eriksson M; Fasching PA; Figueroa JD; Gabrielson M; Gago-Dominguez M; Garcia-Closas M; Gonzalez-Neira A; Grassmann F; Guenel P; Guendert M; Hadjisavvas A; Hahnen E; Hall P; Hamann U; Harrington PA; He W; Hillemanns P; Hollestelle A; Hooning MJ; Hoppe R; Howell A; Humphreys K; Jager A; Jakubowska A; Khusnutdinova EK; Ko Y-D; Kristensen VN; Lindblom A; Lissowska J; Lubinski J; Mannermaa A; Manoukian S; Margolin S; Mavroudis D; Newman WG; Obi N; Panayiotidis MI; Rashid MU; Rhenius V; Rookus MA; Saloustros E; Sawyer EJ; Schmutzler RK; Shah M; Sironen R; Southey MC; Suvanto M; Tollenaar RAEM; Tomlinson I; Truong T; van der Kolk LE; van Veen EM; Wappenschmidt B; Yang XR; Bolla MK; Dennis J; Dunning AM; Easton DF; Lush M; Michailidou K; Pharoah PDP; Wang Q; Adank MA; Schmidt MK; Andrulis IL; Chang-Claude J; Nevanlinna H; Chenevix-Trench G; Evans DG; Milne RL; Radice P; Peterlongo P
  • Journal article: EXPERIMENTAL EYE RESEARCH. 2022;225:109248
    den Hollander AI; Mullins RF; Orozco LD; Voigt AP; Chen H-H; Strunz T; Grassmann F; Haines JL; Kuiper JJW; Tumminia SJ; Allikmets R; Hageman GS; Stambolian D; Klaver CCW; Boeke JD; Chen H; Honigberg L; Katti S; Frazer KA; Weber BHF; Gorin MB
  • Article: DIABETOLOGIA. 2022;65(10):1676-1686
    Wang W; Luo J; Willems van Dijk K; Hagg S; Grassmann F; 't Hart LM; van Heemst D; Noordam R
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All other publications

  • Preprint: BIORXIV. 2023
    Pfaller AM; Kaplan L; Carido M; Grassmann F; Díaz-Lezama N; Ghaseminejad F; Wunderlich KA; Glänzer S; Pannicke T; Weber BHF; Koch SF; Bonev B; Hauck SM; Grosche A
  • Preprint: RES SQ. 2023;RES SQ
    Morra A; Schreurs MAC; Andrulis IL; Anton-Culver H; Augustinsson A; Beckmann MW; Behrens S; Bojesen SE; Bolla MK; Brauch H; Broeks A; Buys SS; Camp NJ; Castelao JE; Cessna MH; Chang-Claude J; Chung WK; Collaborators N; Colonna SV; Couch FJ; Cox A; Cross SS; Czene K; Daly MB; Dennis J; Devilee P; Dörk T; Dunning AM; Dwek M; Easton DF; Eccles DM; Eriksson M; Evans DG; Fasching PA; Fehm TN; Figueroa JD; Flyger H; Gabrielson M; Gago-Dominguez M; García-Closas M; García-Sáenz JA; Genkinger J; Grassmann F; Gündert M; Hahnen E; Haiman CA; Hamann U; Harrington PA; Hartikainen JM; Hoppe R; Hopper JL; Houlston RS; Howell A; Investigators A; Investigators K; Jakubowska A; Janni W; Jernström H; John EM; Johnson N; Jones ME; Kristensen VN; Kurian AW; Lambrechts D; Marchand LL; Lindblom A; Lubiński J; Lux MP; Mannermaa A; Mavroudis D; Mulligan AM; Muranen TA; Nevanlinna H; Nevelsteen I; Neven P; Newman WG; Obi N; Offit K; Olshan AF; Park-Simon T-W; Patel AV; Peterlongo P; Phillips K-A; Plaseska-Karanfilska D; Polley EC; Presneau N; Pylkäs K; Rack B; Radice P; Rashid MU; Rhenius V; Robson M; Romero A; Saloustros E; Sawyer EJ; Schmutzler RK; Schuetze S; Scott C; Shah M; Smichkoska S; Southey MC; Tapper WJ; Teras LR; Tollenaar RAEM; Tomczyk K; Tomlinson I; Troester MA; Vachon CM; van Veen EM; Wang Q; Wendt C; Wildiers H; Winqvist R; Ziogas A; Hall P; Pharoah PDP; Adank MA; Hollestelle A; Schmidt MK; Hooning MJ
  • Preprint: MEDRXIV. 2021
    Martens L; Luo J; Wermer M; van Dijk KW; Hägg S; Grassmann F; Noordam R; van Heemst D
  • Preprint: MEDRXIV. 2021
    Yang H; Bhoo-Pathy N; Brand J; Hedayati E; Grassmann F; Zeng E; Bergh J; Bian W; Ludvigsson J; Hall P; Czene K
  • Preprint: BIORXIV. 2021
    McEwan AR; Hing B; Erickson JC; Turnbull Y; Delibegovic M; Grassmann F; MacKenzie A
  • Preprint: MEDRXIV. 2021
    Luo J; Noordam R; Jukema W; van Dijk KW; Hägg S; Grassmann F; Cessie SL; van Heemst D
  • Corrigendum: HUMAN GENETICS. 2021;140(6):863
    Hagg S; Jylhava J; Wang Y; Czene K; Grassmann F
  • Preprint: BIORXIV. 2020
    Hägg S; Jylhävä J; Wang Y; Czene K; Grassmann F
  • Published conference paper: OPHTHALMOLOGY. 2020;127(2):186-195
    Liao DS; Grossi FV; El Mehdi D; Gerber MR; Brown DM; Heier JS; Wykoff CC; Singerman LJ; Abraham P; Grassmann F; Nuernberg P; Weber BHF; Deschatelets P; Kim RY; Chung CY; Ribeiro RM; Hamdani M; Rosenfeld PJ; Boyer DS; Slakter JS; Francois CG
  • Preprint: BIORXIV. 2019
    Winkler TW; Grassmann F; Brandl C; Kiel C; Günther F; Strunz T; Weidner L; Zimmermann ME; Korb CA; Poplawski A; Schuster AK; Müller-Nurasyid M; Peters A; Rauscher FG; Elze T; Horn K; Scholz M; Cañadas-Garre M; McKnight AJ; Quinn N; Hogg RE; Küchenhoff H; Heid IM; Stark KJ; Weber BH
  • Conference publication: GLIA. 2019;67:E629
    Pauly D; Agarwal D; Dana N; Schafer N; Grassmann F; Zhang NR; Gautam AK; Weber BHF; Hauck SM; Kim M; Curcio C; Stambolian D; Li M; Grosche A
  • Conference publication: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2019;60(9)
    Khan M; Cornelis S; Valero MDP; Khan MI; Stohr H; Grassmann F; Steehouwer M; Hoischen A; Ayuso C; Ramesar R; Meunier IA; Defoort S; Weber BHF; Dhaenens C-M; Cremers FP
  • Conference publication: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2019;60(9)
    Ploessl K; Lauer A; Kiel C; Brandl C; Grassmann F; Weber BHF
  • Preprint: BIORXIV. 2018
    Pauly D; Schäfer N; Grassmann F; Pfaller AM; Straub T; Weber BHF; Hauck SM; Grosche A
  • Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2018;1074:247-255
    Kiel C; Weber BHF; Grassmann F
  • Review: MOLECULAR DIAGNOSIS & THERAPY. 2017;21(1):31-43
    Berber P; Grassmann F; Kiel C; Weber BHF
  • Review: JOURNAL OF CLINICAL MEDICINE. 2015;4(2):282-303
    Brandl C; Grassmann F; Riolfi J; Weber BHF
  • Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2014;801:291-300
    Grassmann F; Heid IM; Weber BHF

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