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I received my PhD from the University of Basel, Switzerland. During my PhD, I worked on small RNA-mediated regulation of stem cell differentiation at the Friedrich Miescher Institute (Basel, Switzerland). As a postdoctoral researcher, I jointed Cancer Research UK and the University of Cambridge (Cambridge, UK) to study the evolution of noncoding RNAs using next-generation sequencing (NGS) methods. In 2016, I became a SciLifeLab and Wallenberg fellow at ̽����ѡ, Department of Microbiology, Tumor and Cell Biology. I am leading my independent research group at the Science for Life Laboratory (SciLifeLab) in Stockholm (Sweden).

Deciphering genome functionality

Cells do not exist in one form and adapt quickly, especially in response to metabolic changes. My group studies how this reversible cell phenotype is controlled by a sophisticated entwined interaction between RNA (long noncoding, transfer and small RNAs) and RNA-binding proteins with a particular focus on liver diseases (from fatty liver to liver cancer). We have developed and used experimental and computational multi-omics approaches (bulk and single cell genomics, transcriptomics, CRISPR technology combined with cell-based assays) to understand the differences between healthy, reversible, and diseased liver cell phenotypes. Our long-term goal is to integrate RNA and their regulators in bio̽����ѡ research not only for diagnosis and prognosis but also for therapeutic purposes.

Conference organiser

EMBO workshop ""

EpiChrom

SciLifeLab seminar series

BSc/MSc course

Methods and Concepts in Molecular Life Sciences

MSc courses

Genomics for Bio̽����ѡ scientist: Handle your gene expression data

PhD courses

Genomics for Bio̽����ѡ scientist: Handle your gene expression data

Non-coding RNAs, microRNAs and their role in human diseases

The future of medicine: the role of "chance" in development, evolutionary adaptation and diseases

Mechanisms of gene regulation in metabolism

Molecular immunology: noncoding RNAs

The epigenome: a platform for the integration of metabolic and signaling pathways in development and on the path to diseases

Epigenetics and its applications in clinical research