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Björn Fischler

Björn Fischler

Adjunct Professor
Visiting address: Enheten för pediatrik, Novum, Blickagången 6A, 14157 Huddinge
Postal address: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Pediatrik, 141 52 Huddinge
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About me

  • Adjunct Professor of Paediatrics specialising in liver diseases at the
    Department of Clinical Science, Intervention and Technology as of 1 January
    2021. Primary position: Senior consultant at the Astrid Lindgren Children’s
    Hospital, Karolinska University Hospital

Research

  • Björn Fischler’s research deals with liver disease in children,
    particularly different forms of cholestasis. His research is conducted within
    international networks and in collaboration with preclinical groups. Fischler
    has demonstrated an association between cytomegalovirus (CMV) infection and
    biliary atresia. He now intends to study whether anti-CMV medication can
    improve the severe prognosis.
    Fischler has planned and participated in an international clinical study
    showing that a new drug effectively mitigates the symptoms of the cholestatic
    condition PFIC and probably improves survival rates. The phase III study has
    recently been concluded and the drug has been licensed in Europe and USA. For
    another cholestatic disease, Alagille's syndrome, which also affects other
    organs as well as trhe immune system, Fischler is collaborating with Emma
    Andersson’s research group at KI, which has developed a mouse model. This,
    in combination with clinical data from patients, can be used to explain
    pathophysiologies and test new therapies.

Articles

  • Article: INFECTIOUS DISEASES. 2024;56(10):907-917
    Swartling L; Engman M-L; Eriksen J; Fischler B; Friman V; Hobell H; Ljungman P; Mellgren K; Naver L; Nystroem K; Otto G; Pauksens K; Pettersson K; Ryden I; Westman G; Magnusson J
  • Article: JPGN REP. 2024;5(3):303-308
    Liliemark U; Psaros Einberg A; Svensson JF; Fischler B
  • Article: HEPATOLOGY. 2024;79(6):1279-1292
    Hansen BE; Vandriel SM; Vig P; Garner W; Mogul DB; Loomes KM; Piccoli DA; Rand EB; Jankowska I; Czubkowski P; Gliwicz-Miedzinska D; Gonzales EM; Jacquemin E; Bouligand J; D'Antiga L; Nicastro E; Arnell H; Fischler B; Sokal E; Demaret T; Siew S; Stormon M; Karpen SJ; Romero R; Ebel NH; Feinstein JA; Roberts AJ; Evans HM; Sundaram SS; Chaidez A; Hardikar W; Shankar S; Fischer RT; Lacaille F; Debray D; Lin HC; Jensen MK; Jaramillo C; Karthikeyan P; Indolfi G; Verkade HJ; Larson-Nath C; Quiros-Tejeira RE; Valentino PL; Rogalidou M; Dezsofi A; Squires JE; Schwarz K; Calvo PL; Bernabeu JQ; Zizzo AN; Nebbia G; Bulut P; Santos-Silva E; Fawaz R; Nastasio S; Karnsakul W; Tamara ML; Busoms CM; Kelly DA; Sandahl TD; Jimenez-Rivera C; Banales JM; Mujawar Q; Li L-T; She H; Wang J-S; Kim KM; Oh SH; Sanchez MC; Cavalieri ML; Lee WS; Hajinicolaou C; Lertudomphonwanit C; Waisbourd-Zinman O; Arikan C; Alam S; Carvalho E; Melere M; Eshun J; Onal Z; Desai DM; Wiecek S; Pinto RB; Wolters VM; Garcia J; Beretta M; Kerkar N; Brecelj J; Rock N; Lurz E; Blondet N; Shah U; Thompson RJ; Kamath BM
  • Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2024;78(4):957-972
    Indolfi G; Gonzalez-Peralta RP; Jonas MM; Sayed MH-E; Fischler B; Sokal E; Wirth S; Nicastro E
  • Article: ORPHANET JOURNAL OF RARE DISEASES. 2023;18(1):383
    Gardin A; Ruiz M; Beime J; Cananzi M; Rathert M; Rohmer B; Grabhorn E; Almes M; Logarajah V; Pena-Quintana L; Casswall T; Darmellah-Remil A; Reyes-Dominguez A; Barkaoui E; Hierro L; Baquero-Montoya C; Baumann U; Fischler B; Gonzales E; Davit-Spraul A; Laplanche S; Jacquemin E
  • Journal article: WFUMB ULTRASOUND OPEN. 2023;1(2):100024
    Torres A; Fischler B; Koskinen SK
  • Article: PEDIATRIC TRANSPLANTATION. 2023;27(7):e14589
    Dona D; Bravo-Gallego LY; Remacha EF; Cananzi M; Gastaldi A; Canizalez JT; Stephenne X; Lacaille F; Lindemans C; Calore E; Galea N; Benetti E; Nachbaur E; Sandes AR; Teixeira A; Ferreira S; Klaudel-Dreszler M; Ackermann O; Boyer O; Espinosa L; Guereta LG; Sciveres M; Fischler B; Schwerk N; Neland M; Nicastro E; Dello Strologo L; Toporski J; Vainumae I; Rascon J; Urbonas V; del Rosal T; Lopez-Granados E; Perilongo G; Baker A; Vega PJ
  • Article: TRANSPLANTATION. 2023;107(11):2394-2405
    Hartleif S; Hodson J; Lloyd C; Cousin VL; Czubkowski P; D'Antiga L; Debray D; Demetris A; Di Giorgio A; Evans HM; Fischler B; Gonzales E; Gouw ASH; Hubscher SG; Jacquemin E; Lacaille F; Malenicka S; McLin VA; Markiewicz-Kijewska M; Mazariegos GV; Rajanayagam JK; Scheenstra R; Singer S; Smets F; Sokal E; Squires JE; Sturm E; Verkade H; Kelly DA
  • Journal article: JOURNAL OF HEPATOLOGY. 2023;78:s433
    Verboven E; Van Hul NKM; Hankeova S; Adori C; Ellis E; Fischler B; Andersson E
  • Article: HEPATOLOGY COMMUNICATIONS. 2023;7(3):e0031
    Gonzalez-Peralta RP; Wirth S; Squires RH; Mutschler F; Lang T; Pawlowska M; Sluzewski W; Majda-Stanislawska E; Fischler B; Balistreri WF; Jonas MM; Blondet N; Rosenthal P; Alkhouri N; Romero R; Grandhi A; Castronuovo P; Caro L; Du L; Rosenbloom DIS; Haber BA
  • Article: PEDIATRIC SURGERY INTERNATIONAL. 2023;39(1):117
    Liliemark U; Svensson JF; Fischler B
  • Article: JHEP REPORTS. 2023;5(2):100626
    Felzen A; van Wessel DBE; Gonzales E; Thompson RJ; Jankowska I; Shneider BL; Sokal E; Grammatikopoulos T; Kadaristiana A; Jacquemin E; Spraul A; Lipinski P; Czubkowski P; Rock N; Shagrani M; Broering D; Nicastro E; Kelly D; Nebbia G; Arnell H; Fischler B; Hulscher JBF; Serranti D; Arikan C; Polat E; Debray D; Lacaille F; Goncalves C; Hierro L; Bartolo GM; Mozer-Glassberg Y; Azaz A; Brecelj J; Dezsofi A; Calvo PL; Grabhorn E; Hartleif S; van der Woerd WJ; Kamath BM; Wang J-S; Li L; Durmaz O; Kerkar N; Jorgensen MH; Fischer R; Jimenez-Rivera C; Alam S; Cananzi M; Laverdure N; Ferreira CT; Guerrero FO; Wang H; Sency V; Kim KM; Chen H-L; de Carvalho E; Fabre A; Bernabeu JQ; Zellos A; Alonso EM; Sokol RJ; Suchy FJ; Loomes KM; McKiernan PJ; Rosenthal P; Turmelle Y; Horslen S; Schwarz K; Bezerra JA; Wang K; Hansen BE; Verkade HJ
  • Article: HEPATOLOGY. 2023;77(2):512-529
    Vandriel SM; Li L-T; She H; Wang J-S; Gilbert MA; Jankowska I; Czubkowski P; Gliwicz-Miedzinska D; Gonzales EM; Jacquemin E; Bouligand J; Spinner NB; Loomes KM; Piccoli DA; D'Antiga L; Nicastro E; Sokal E; Demaret T; Ebel NH; Feinstein JA; Fawaz R; Nastasio S; Lacaille F; Debray D; Arnell H; Fischler B; Siew S; Stormon M; Karpen SJ; Romero R; Kim KM; Baek WY; Hardikar W; Shankar S; Roberts AJ; Evans HM; Jensen MK; Kavan M; Sundaram SS; Chaidez A; Karthikeyan P; Sanchez MC; Cavalieri ML; Verkade HJ; Lee WS; Squires JE; Hajinicolaou C; Lertudomphonwanit C; Fischer RT; Larson-Nath C; Mozer-Glassberg Y; Arikan C; Lin HC; Bernabeu JQ; Alam S; Kelly DA; Carvalho E; Ferreira CT; Indolfi G; Quiros-Tejeira RE; Bulut P; Calvo PL; Onal Z; Valentino PL; Desai DM; Eshun J; Rogalidou M; Dezsofi A; Wiecek S; Nebbia G; Pinto RB; Wolters VM; Tamara ML; Zizzo AN; Garcia J; Schwarz K; Beretta M; Sandahl TD; Jimenez-Rivera C; Kerkar N; Brecelj J; Mujawar Q; Rock N; Busoms CM; Karnsakul W; Lurz E; Santos-Silva E; Blondet N; Bujanda L; Shah U; Thompson RJ; Hansen BE; Kamath BM
  • Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(3):775
    Nomden M; Alizai NK; Betalli P; Bruggink JLM; Cananzi M; Christensen VB; D'Antiga L; Davenport M; Fischler B; Hindemith L; Hukkinen M; Johansen LS; de Kleine RH; Madadi-Sanjani O; Ong EGP; Pakarinen MP; Petersen C; Ruiz M; Schunn M; Sturm E; Verkade HJ; Wildhaber BE; Hulscher JBF
  • Article: TRANSPLANT INTERNATIONAL. 2023;36:11729
    Carbone M; Della Penna A; Mazzarelli C; De Martin E; Villard C; Bergquist A; Line PD; Neuberger JM; Al-Shakhshir S; Trivedi PJ; Baumann U; Cristoferi L; Hov J; Fischler B; Hadzic NH; Debray D; D'Antiga L; Selzner N; Belli LS; Nadalin S
  • Article: EMBO MOLECULAR MEDICINE. 2022;14(12):e15809
    Hankeova S; Van Hul N; Laznovsky J; Verboven E; Mangold K; Hensens N; Adori C; Verhoef E; Zikmund T; Dawit F; Kavkova M; Salplachta J; Sjoqvist M; Johansson BR; Hassan MG; Fredriksson L; Baumgartel K; Bryja V; Lendahl U; Jheon A; Alten F; Fahnehjelm KT; Fischler B; Kaiser J; Andersson ER
  • Article: ISCIENCE. 2022;25(10):105070
    Stone VM; Utorova R; Butrym M; Sioofy-Khojine A-B; Hankaniemi MM; Ringqvist EE; Blanter M; Parajuli A; Pincikova T; Fischler B; Karpati F; Hytonen VP; Hyoty H; Hjelte L; Flodstrom-Tullberg M
  • Article: LANCET GASTROENTEROLOGY & HEPATOLOGY. 2022;7(9):830-842
    Thompson RJ; Arnell H; Artan R; Baumann U; Calvo PL; Czubkowski P; Dalgic B; D'Antiga L; Durmaz O; Fischler B; Gonzales E; Grammatikopoulos T; Gupte G; Hardikar W; Houwen RHJ; Kamath BM; Karpen SJ; Kjems L; Lacaille F; Lachaux A; Lainka E; Mack CL; Mattsson JP; McKiernan P; Ozen H; Rajwal SR; Roquelaure B; Shagrani M; Shteyer E; Soufi N; Sturm E; Tessier ME; Verkade HJ; Horn P
  • Article: JOURNAL OF PERINATOLOGY. 2022;42(6):702-707
    Teng J; Wickman L; Reilly M; Nemeth A; Fischler B; Bohlin K; Tiblad E
  • Article: EUROSURVEILLANCE. 2022;27(19):2200370
    van Beek J; Fraaij PLA; Giaquinto C; Shingadia D; Horby P; Indolfi G; Koopmans M; Acute hepatitis study group
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All other publications

  • Letter: VIRULENCE. 2024;15(1):2318582
    Vajro P; Mandato C; Fischler B
  • Letter: JOURNAL OF CLINICAL MEDICINE. 2024;13(23):7047
    Teng J; Fischler B; Bohlin K; Reilly M; Tiblad E
  • Letter: JOURNAL OF INFECTION. 2024;88(3):106127
    Vajro P; Mandato C; Fischler B
  • Letter: HEPATOLOGY COMMUNICATIONS. 2024;8(2):e0339
    Fischler B; Liliemark U; Einberg AP; Svensson JF
  • Editorial comment: ACTA PAEDIATRICA. 2024;113(1):15-18
    Fischler B; Mandato C; Vajro P
  • Conference publication: GUT. 2023;72(SUPPL_3):A13
    Hansen B; Valcheva V; Yu Q; van Wessel DBE; Thompson RJ; Gonzales E; Jankowska I; Sokal E; Grammatikopoulos T; Kadaristiana A; Jacquemin E; Spraul A; Lipinski P; Czubkowski P; Rock N; Shagrani M; Kumar K; Alkuraya F; Sateesh M; Broering D; Nicastro E; Kelly DA; Nebbia G; Arnell H; Fischler B; Serranti D; Arikan C; Polat E; Debray D; Lacaille F; Goncalves C; Hierro L; Bartolo GM; Mozer-Glassberg Y; Azaz A; Brecelj J; Dezsofi A; Calvo PL; Grabhorn E; Sturm E; van der Woerd WL; Kamath BM; Wang J-S; Li L; Durmaz O; Onal Z; Felzen A; Nomden M; Sonajalg J; Stein P; Ni Q; Clemson C; Mattsson JP; Verkade HJ
  • Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:S971-S973
    Perez CFM; Vandriel SM; Wang J-S; Li L; She H; Jankowska I; Czubkowski P; Gliwicz D; Gonzales E; Jacquemin E; Bouligand J; D'Antiga L; Nicastro E; Fischler B; Arnell H; Siew S; Stormon M; Loomes KM; Piccoli DA; Rand EB; Squires JE; Karpen SJ; Romero R; Kasahara M; Onal Z; Sokal E; Demaret T; Wiecek S; Lacaille F; Debray D; Hardikar W; Shankar S; Valentino P; Sundaram S; Chaidez A; Ebel N; Feinstein J; Mozar-Glazberg Y; Lin H; Rock N; Verkade HJ; Jensen MK; Jaramillo C; Kim K; Oh SH; Brecelj J; Alam S; Indolfi G; Blondet N; Fawaz R; Nastasio S; Calvo PL; Nebbia G; Arikan C; Larson-Nath C; Zizzo AN; Sandahl TD; Tzivinikos C; El-Koofy N; Elmonem M; Desai D; Karnsakul W; Karthikeyan P; Bulut P; Kerkar N; Wolters V; Roberts AJ; Evans H; Sanchez MC; Cavalieri ML; Kelly D; Lee WS; Hajinicolaou C; Lertudomphonwanit C; Fischer R; Bernabeu JQ; Quiros-Tejeira RE; Melere M; Carvalho E; Eshun J; Zellos A; Fi AD; Pinto RB; Schwarz K; Rogalidou M; Garcia J; Tamara ML; Beretta M; Mujawar Q; Santos-Silva E; Busoms CM; Lurz E; Goncalves C; Jimenez-Rivera C; Banales JM; Shah U; Thompson R; Hansen B; Kamath BM
  • Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:S969-S970
    Hansen B; Valcheva V; Yu Q; van Wessel D; Thompson R; Gonzales E; Jankowska I; Sokal E; Grammatikopoulos T; Kadaristiana A; Jacquemin E; Spraul A; Lipinski P; Czubkowski P; Rock N; Shagrani M; Kumar K; Alkuraya F; Sateesh M; Broering DC; Nicastro E; Kelly D; Nebbia G; Arnell H; Fischler B; Serranti D; Arikan C; Polat E; Debray D; Lacaille F; Goncalves C; Llanillo LH; Bartolo GM; Mozer-Glassberg Y; Azaz A; Brecelj J; Dezsofi A; Calvo PL; Grabhorn E; Sturm E; van der Woerd WL; Kamath BM; Wang J-S; Li L; Durmaz O; Onal Z; Felzen A; Nomden M; Sonajalg J; Stein P; Ni Q; Clemson C; Mattsson J; Verkade HJ
  • Conference publication: HEPATOLOGY. 2023;78:S121-S124
    Perez CFM; Vandriel SM; Wang J-S; Li L-T; She H; Jankowska I; Czubkowski P; Gliwicz-Miedzinska D; Gonzales EM; Jacquemin E; Bouligand J; D'Antiga L; Nicastro E; Fischler B; Arnell H; Siew S; Stormon MO; Loomes KM; Piccoli DA; Rand E; Squires JE; Karpen S; Romero R; Kasahara M; Onal Z; Sokal EM; Demaret T; Wiecek S; Lacaille F; Debray D; Hardikar W; Shankar S; Valentino PL; Sundaram SS; Chaidez A; Ebel NH; Feinstein JA; Mozer-Glassberg Y; Lin HC; Rock N; Verkade HJ; Jensen MK; Jaramillo C; Kim KM; Oh SH; Brecelj J; Alam S; Indolfi G; Blondet N; Fawaz RL; Nastasio S; Calvo PL; Nebbia G; Arikan C; Larson-Nath C; Zizzo AN; Sandahl TD; Tzivinikos C; El-Koofy NM; Elmonem MA; Desai DM; Karnsakul W; Karthikeyan P; Bulut P; Kerkar N; Wolters VM; Roberts AJ; Evans HM; Sanchez MC; Cavalieri ML; Kelly DA; Lee WS; Hajinicolaou C; Lertudomphonwanit C; Fischer RT; Bernabeu JQ; Quiros-Tejeira RE; Melere M; Carvalho E; Eshun J; Zellos A; Dezsofi A; Pinto RB; Schwarz KB; Rogalidou M; Garcia J; Tamara ML; Beretta M; Mujawar Q; Santos-Silva E; Busoms CM; Lurz E; Goncalves C; Jimenez-Rivera C; Banales JM; Shah U; Thompson RJ; Hansen BEE; Kamath BM
  • Conference publication: HEPATOLOGY. 2023;78:S20-S23
    Vandriel SM; Loomes KM; Piccoli DA; Rand E; Li L-T; She H; Wang J-S; Fawaz RL; Nastasio S; Verkade HJ; Jensen MK; Jaramillo C; Rock N; Jankowska I; Czubkowski P; Gliwicz-Miedzinska D; Lin HC; Kelly DA; Larson-Nath C; Lacaille F; Debray D; Karpen S; Romero R; Molera Busoms C; Sokal EM; Demaret T; El-Koofy NM; Elmonem MA; Sundaram SS; Chaidez A; Karthikeyan P; Karnsakul W; Hardikar W; Shankar S; Quiros-Tejeira RE; Alam S; Bulut P; Hajinicolaou C; Wolters VM; Onal Z; Gonzales EM; Jacquemin E; Bouligand J; D'Antiga L; Nicastro E; Ebel NH; Feinstein JA; Fischler B; Arnell H; Siew S; Stormon MO; Kim KM; Oh SH; Roberts AJ; Evans HM; Camila Sanchez M; Lorena Cavalieri M; Lee WS; Lertudomphonwanit C; Fischer RT; Waisbourd-Zinman O; Squires JE; Arikan C; Quintero Bernabeu J; Kasahara M; Carvalho E; Ferreira CT; Valentino PL; Indolfi G; Eshun J; Calvo PL; Desai DM; Zellos A; Dezsofi A; Wiecek S; Nebbia G; Pinto RB; Rogalidou M; Legarda Tamara M; Zizzo AN; Garcia J; Schwarz KB; Blondet N; Beretta M; Sandahl TD; Brecelj J; Goncalves C; Lurz E; Santos-Silva E; Kerkar N; Mujawar Q; Tzivinikos C; Shah U; Jimenez-Rivera C; Banales JM; Thompson RJ; Hansen BEE; Kamath BM
  • Editorial comment: ACTA PAEDIATRICA. 2022;111(9):1806-1807
    Einberg AP; Fischler B
  • Editorial comment: ACTA PAEDIATRICA. 2021;110(10):2810-2811
    Psaros Einberg A; Casswall TH; Arnell H; Nowak G; Mirazimi A; Sundin M; Fischler B
  • Preprint: BIORXIV. 2021
    Hankeova S; Van Hul N; Laznovsky J; Hensen N; Verhoef E; Zikmund T; Dawit F; Kavkova M; Salplachta J; Li L; Sjöqvist M; Johansson BR; Hassan M; Bryja V; Lendahl U; Jheon A; Wang JS; Alten F; Fahnehjelm KT; Fischler B; Kaiser J; Andersson ER
  • Editorial comment: ACTA PAEDIATRICA. 2021;110(4):1289-1290
    Marits AK; Fischler B; Chromek M
  • Conference publication: HEPATOLOGY. 2021;74(6):1387A-1389A
    Hansen BE; Vandriel SM; Vig P; Garner W; Li L-T; She H; Wang J-S; Gilbert MA; Jankowska I; Czubkowski P; Gliwicz-Miedzinska D; Gonzales EM; Jacquemin E; Bouligand J; Spinner N; Loomes KM; Piccoli DA; D'Antiga L; Nicastro E; Sokal E; Demaret T; Ebel N; Feinstein JA; Fawaz R; Nastasio S; Lacaille F; Debray D; Arnell H; Fischler B; Siew S; Stormon M; Karpen SJ; Romero R; Kim KM; Baek WY; Hardikar W; Shankar S; Roberts AJ; Evans HM; Jensen MK; Kavan M; Sundaram SS; Chaidez A; Karthikeyan P; Davison S; Sanchez MC; Cavalieri ML; Verkade HJ; Lee WS; Squires JE; Hajinicolaou C; Lertudomphonwanit C; Fischer RT; Larson-Nath C; Mozer-Glassberg Y; Arikan C; Lin HC; Bernabeu JQ; Alam S; Kelly D; Carvalho E; Ferreira CT; Indolfi G; Quiros-Tejeira RE; Bulut P; Calvo PL; Onal Z; Valentino PL; Desai DM; Eshun J; Rogalidou M; Dezsofi A; Wiecek S; Nebbia G; Pinto RB; Wolters VM; Tamara ML; Zizzo AN; Garcia J; Schwarz K; Beretta M; Sandahl TD; Jimenez-Rivera C; Kerkar N; Brecelj J; Mujawar Q; Rock N; Molera C; Karnsakul W; Lurz E; Santos-Silva E; Blondet N; Bujanda L; Shah U; Thompson RJ; Kamath BM
  • Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:87
    Bluhme E; Malenicka S; Fischler B; Nemeth A; Berg U; Jorns C
  • Conference publication: HEPATOLOGY. 2021;74:1175A-1176A
    Jorgensen MHH; Almaas R; Kharrazi G; Urbonas V; Wollen EJ; Andreassen BU; Casswall T; Fischler B
  • Conference publication: PEDIATRIC RESEARCH. 2021;90(SUPPL 1):33
    Teng J; Elwin A; Omarsdottir S; Aquilano G; Vanpee M; Nemeth A; Rahbar A; Bohlin K; Fischler B; Soderberg-Naucler C
  • Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:85
    de la Maza LM; Casswall T; Magnusson M; Fischler B; Sund M; Dlugosz R; Jorns C; Delle M
  • Editorial comment: ACTA PAEDIATRICA. 2020;109(12):2441-2442
    Psaros Einberg A; Fischler B
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Employments

  • Adjunct Professor, Department of Clinical Science, Intervention and Technology, ̽ѡ, 2021-2028

Degrees and Education

  • Docent, ̽ѡ, 2003
  • Doctor Of Philosophy, Department of Clinical Science, Intervention and Technology, ̽ѡ, 1998

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