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Bernhard Schmierer

Bernhard Schmierer

Researcher
Visiting address: Biomedicum Solnav盲gen 9, 17165 Solna
Postal address: C2 Medicinsk biokemi och biofysik, C2 Chemical Biology and Genome engineering Bernhard, 171 77 Stockholm
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About me

  • I am heading CRISPR Functional Genomics (CFG), formerly High Throughput
    Genome Engineering, a National SciLifeLab Facility offering massively
    parallel CRISPR-Cas applications to the Swedish and international research
    communities.

Research

  • Pooled CRISPR-Cas screening approaches enables parallel interrogation of
    thousands of protein coding genes, lncRNAs or other genetic elements for
    involvement in biological processes of interest. CFG provides access to
    verified lentiviral CRISPR guide libraries for whole genome and targeted
    loss- and gain of function studies (CRISPR knock-out, CRISPR inhibition,
    CRISPR activation, base-editing mutagenesis screens). CFG offers support from
    experimental design to data analysis.

Articles

  • Journal article: CANCERS. 2024;16(13):2437
    Issa II; Due H; Brondum RF; Veeravakaran V; Haraldsdottir H; Sylvester C; Brogaard A; Dhanjal S; Schmierer B; Dybkaer K
  • Journal article: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2024;9(1):32
    Durinova A; Smutna L; Barta P; Kamaraj R; Smutny T; Schmierer B; Pavek P; Trejtnar F
  • Journal article: CANCER RESEARCH. 2024;84(6):2025
    Dam N; Harryvan TJ; Schmierer B; Hawinkels LJAC; Kemp V
  • Article: NATURE COMMUNICATIONS. 2023;14(1):5024
    Moro CF; Geyer N; Harrizi S; Hamidi Y; Soderqvist S; Kuznyecov D; Tidholm Qvist E; Salmonson Schaad M; Hermann L; Lindberg A; Heuchel RL; Martin-Bernabe A; Dhanjal S; Navis AC; Villard C; del Valle AC; Bozoky L; Sparrelid E; Dirix L; Strell C; Ostman A; Schmierer B; Vermeulen PB; Engstrand J; Bozoky B; Gerling M
  • Journal article: CANCER RESEARCH. 2023;83(7):3778
    Weiss S; Lord A; Schmierer B; Rovsing AB; Thomsen EA; Mikkelsen JG; Ulhoi B; Pedersen JS; Borre M; Sorensen KD
  • Article: FRONTIERS IN ONCOLOGY. 2022;12:852980
    Gubat J; Selvaraju K; Sjoestrand L; Kumar Singh D; Turkina MV; Schmierer B; Sabatier P; Zubarev RA; Linder S; D'Arcy P
  • Article: ELIFE. 2021;10:e75415
    Reint G; Li Z; Labun K; Keskitalo S; Soppa I; Mamia K; Tolo E; Szymanska M; Meza-Zepeda LA; Lorenz S; Cieslar-Pobuda A; Hu X; Bordin DL; Staerk J; Valen E; Schmierer B; Varjosalo M; Taipale J; Haapaniemi E
  • Article: JOURNAL OF CELL SCIENCE. 2019;132(14):jcs234039
    Miller DSJ; Schmierer B; Hill CS
  • Article: NATURE COMMUNICATIONS. 2018;9(1):3664
    Palin K; Pitkanen E; Turunen M; Sahu B; Pihlajamaa P; Kivioja T; Kaasinen E; Valimaki N; Hanninen UA; Cajuso T; Aavikko M; Tuupanen S; Kilpivaara O; van den Berg L; Kondelin J; Tanskanen T; Katainen R; Grau M; Rauanheimo H; Plaketti R-M; Taira A; Sulo P; Hartonen T; Dave K; Schmierer B; Botla S; Sokolova M; Vaharautio A; Gladysz K; Ongen H; Dermitzakis E; Bramsen JB; Orntoft TF; Andersen CL; Ristimaki A; Lepisto A; Renkonen-Sinisalo L; Mecklin J-P; Taipale J; Aaltonen LA
  • Article: NATURE MEDICINE. 2018;24(7):927-930
    Haapaniemi E; Botla S; Persson J; Schmierer B; Taipale J
  • Article: MOLECULAR SYSTEMS BIOLOGY. 2017;13(10):945
    Schmierer B; Botla SK; Zhang J; Turunen M; Kivioja T; Taipale J
  • Article: NATURE COMMUNICATIONS. 2015;6:10050
    Morgunova E; Yin Y; Jolma A; Dave K; Schmierer B; Popov A; Eremina N; Nilsson L; Taipale J
  • Article: SCIENCE SIGNALING. 2013;6(305):ra106
    Vizan P; Miller DSJ; Gori I; Das D; Schmierer B; Hill CS
  • Article: CELL. 2013;154(4):801-813
    Yan J; Enge M; Whitington T; Dave K; Liu J; Sur I; Schmierer B; Jolma A; Kivioja T; Taipale M; Taipale J
  • Article: BIOPHYSICAL JOURNAL. 2013;104(12):2595-2606
    Zhang T; Oliveira RA; Schmierer B; Novak B
  • Article: OPEN BIOLOGY. 2011;1(3):110009
    Zhang T; Schmierer B; Novak B
  • Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(9):7648-7660
    Yang M; Ge W; Chowdhury R; Claridge TDW; Kramer HB; Schmierer B; McDonough MA; Gong L; Kessler BM; Ratcliffe PJ; Coleman ML; Schofield CJ
  • Article: INTEGRATIVE BIOLOGY (UNITED KINGDOM). 2011;3(3):197-207
    Gonzalez-Perez V; Schmierer B; Hill CS; Sear RP
  • Article: BMC SYSTEMS BIOLOGY. 2010;4:139
    Schmierer B; Novak B; Schofield CJ
  • Article: DEVELOPMENT. 2008;135(17):2927-2937
    Batut J; Schmierer B; Cao J; Raftery LA; Hill CS; Howell M
  • Show more

All other publications

  • Preprint: BIORXIV. 2024
    Sait MRB; Jachmann LH; Milivojevic M; Llorente-S谩ez C; Dhanjal S; Schumacher F; Henriksson S; Vegesna NVG; Chaban A; Mohanty P; 脰lander M; Muraleedharan S; Azadeh SF; Kleuser B; Schmierer B; Sixt BS
  • Preprint: BIORXIV. 2024
    S枚derqvist S; Viljamaa A; Geyer N; Strell C; Hekmati N; Engstrand J; Sparrelid E; Salm茅n C; Heuchel R; Zacharouli A; Ghorbani P; Harrizi S; Hamidi Y; Khorosjutina O; Milanova S; Schmierer B; Boz贸ky B; Moro CF; Gerling M
  • Book chapter: GENOME EDITING IN DRUG DISCOVERY. 2022;p. 151-164
    Persson J; Schmierer B
  • Conference publication: CANCER RESEARCH. 2022;82(22):5
    Laise P; Turunen M; Maurer HC; Garcia AC; Elyada E; Schmierer B; Tomassoni L; Worley J; Alvarez MJ; Kesner J; Tan X; Tagore S; Fernandez EC; Wong K; Wang ALE; Ge S; Iuga AC; Griffin AT; Wong W; Manji GA; Notta F; Tuveson DA; Olive KPP; Califano A
  • Conference publication: MOLECULAR THERAPY. 2022;30(4):267
    Reint G; Li Z; Labun K; Keskitalo S; Soppa I; Mamia K; Tolo E; Szymanska M; Meza-Zepeda L; Lorenz S; Cieslar-Pobuda A; Hu X; Bordin D; Staerk J; Valen E; Schmierer B; Varjosalo M; Taipale J; Haapaniemi E
  • Preprint: BIORXIV. 2020
    Laise P; Turunen M; Garcia AC; Tomassoni L; Maurer C; Elyada E; Schmierer B; Worley J; Kesner J; Tan X; Fernandez EC; Wong K; Wasko U; Tagore S; Wang A; Ge S; Iuga A; Griffin A; Wong W; Manji G; Alvarez M; Notta F; Tuveson D; Olive K; Califano A
  • Review: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL. 2020;18:2237-2246
    Iyer VS; Jiang L; Shen Y; Boddul SV; Panda SK; Kasza Z; Schmierer B; Wermeling F
  • Letter: MOLECULAR SYSTEMS BIOLOGY. 2019;15(8):e9059
    Haapaniemi E; Botla S; Persson J; Schmierer B; Taipale J
  • Letter: SCIENCE SIGNALING. 2014;7(344):lc2
    Vizan P; Miller DSJ; Schmierer B; Hill CS
  • Book chapter: ENCYCLOPEDIA OF SYSTEMS BIOLOGY. 2013;p. 29
    Schmierer B
  • Book chapter: ENCYCLOPEDIA OF SYSTEMS BIOLOGY. 2013;p. 311-314
    Schmierer B
  • Book chapter: ENCYCLOPEDIA OF SYSTEMS BIOLOGY. 2013;p. 1055-1056
    Schmierer B
  • Book chapter: ENCYCLOPEDIA OF SYSTEMS BIOLOGY. 2013;p. 1846
    Schmierer B
  • Book chapter: ENCYCLOPEDIA OF SYSTEMS BIOLOGY. 2013;p. 1802
    Schmierer B
  • Book chapter: ENCYCLOPEDIA OF SYSTEMS BIOLOGY. 2013;p. 434
    Schmierer B
  • Corrigendum: INTEGRATIVE BIOLOGY (UNITED KINGDOM). 2011;3(12):1233
    Gonzalez-Perez V; Schmierer B; Hill CS; Sear RP
  • Review: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2007;8(12):970-982
    Schmierer B; Hill CS
  • Book chapter: SMAD SIGNAL TRANSDUCTION: PROTEINS AND CELL REGULATION. 2006;p. 193-213
    Schmierer B; Hill CS

Grants

  • Swedish Research Council
    1 January 2023 - 31 December 2025
  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • FWF Austrian Science Fund
    1 June 2004 - 31 May 2006

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