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Begum Horuluoglu

Begum Horuluoglu

Assistant Professor
Visiting address: D2:01, Karolinska Universitetssjukhuset, 17177 Stockholm
Postal address: K2 Medicin, Solna, K2 Reuma Jakobsson P Alexanderson H, 171 77 Stockholm

About me

  • 2023- Assistant Professor, Division of Rheumatology, Center for Molecular Medicine, KI

    2019-2023: Postdoc, Division of Rheumatology, Center for Molecular Medicine, KI

    2014-2019: PhD, Molecular Biology and Genetics, Bilkent University, Turkiye & National Cancer Instiute, NIH, USA (Graduate Partnership Program)

Research

  • My research interest is to understand the immunological mechanisms that leads to autoimmunity. Having my PhD through a partnership programme between Bilkent University, Turkey, and the National Cancer Institute, National Institutes of Health, USA, I've gained a diverse academic background. With extensive training and research training in cancer immunology and autoimmunity my PhD thesis focused on investigating TLR agonists as a therapeutic tool for cancer and autoimmune diseases. Subsequently I joined Prof Ingrid Lundbergs research group to pursue my interest to understand the cellular mechanisms involved in autoimmune diseases and how we can develop targeted therapies. Our collaborative efforts extend across disciplines, working closely with e the Rheumatology Clinic (KS), T cell experts Assoc Prof Karine Chemin and Professor Vivianne Malmström, antibody engineering expert Assoc Prof Caroline Grönwall, and bioinformatics expert Assist Profe Lina Diaz Gallo.

    Since August 2023, I've held the position of Assistant Professor within Prof Lundberg's group. My focus has been on integrating molecular techniques with bioinformatic approaches to gain deeper insights into disease pathogenesis in autoimmunity with a focus on myositis. I am currently the main supervisor of a PhD student, a postdoc and a research assistant dedicated to understand the molecular mechanisms of an autoimmune disease called myositis. We are using state of the art technologies such as in-situ hybridization and single cell sequencing along with classical molecular techniques like multi-paramter flow cytometry, ELISA, IHC/IF.
     
    Research Support:
    The Myositis Association (TMA)
    Ã…ke Wiberg Stiftelse
    Alex and Eva Wallströms Stfitelse
    Professor Nanna Svartz Stiftelse
    Stiftelsen Konung Gustaf V:s 80-Ã¥rs fond
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    KI Research Foundations

Teaching

  • 2024: R workshop for multi-color flow cytometry analysis, Workshop co-organizer, KI, Stockholm, Sweden
    2023: Basic Inflammation 2705, Course co-organizer, KI, Stockholm, Sweden
    2019-2020: Introduction to Basic Immunology, Mentor, KI, Stockholm, Sweden
    2018: Journal Club for Summer Students, NCI, NIH, Frederick, USA
    2012-2017: Graduate Teaching Assistant, Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
    2008-2009: Student Teaching Assistant, Department of Chemistry, Istanbul Technical University, Istanbul, Turkey

Articles

  • Article: RHEUMATOLOGY. 2024;:1482-1492
    Galindo-Feria AS; Lodin K; Horuluoglu B; Sarrafzadeh-Zargar S; Wigren E; Graslund S; Danielsson O; Wahren-Herlenius M; Dastmalchi M; Lundberg IE
  • Article: RHEUMATOLOGY. 2024;63(5):1466-1473
    Van Gompel E; Demirdal D; Fernandes-Cerqueira C; Horuluoglu B; Galindo-Feria A; Wigren E; Graslund S; De Langhe E; Benveniste O; Notarnicola A; Chemin K; Lundberg IE
  • Article: EMBO MOLECULAR MEDICINE. 2023;15(10):e17240
    Argyriou A; Horuluoglu B; Galindo-Feria AS; Diaz-Boada JS; Sijbranda M; Notarnicola A; Dani L; van Vollenhoven A; Ramskold D; Nennesmo I; Dastmalchi M; Lundberg IE; Diaz-Gallo L-M; Chemin K
  • Article: KIDNEY INTERNATIONAL. 2023;103(5):973-985
    Sharma RK; Yoosuf N; Afonso M; Scheffschick A; Avik A; Bartoletti A; Horuluoglu B; Boada JSD; Boddul SK; Jonasdottir AD; Lovstrom B; Brauner H; Raposo B; Chemin K; Bruchfeld A; Gunnarsson I; Malmstrom V
  • Article: JOURNAL OF AUTOIMMUNITY. 2023;136:103022
    Hensvold A; Horuluoglu B; Sahlstrom P; Thyagarajan R; Boada JSD; Hansson M; Mathsson-Alm L; Gerstner C; Sippl N; Israelsson L; Wedin R; Steen J; Klareskog L; Rethi B; Catrina AI; Diaz-Gallo L-M; Malmstrom V; Gronwall C
  • Article: RHEUMATOLOGY. 2022;61(10):4145-4154
    Galindo-Feria AS; Horuluoglu B; Day J; Fernandes-Cerqueira C; Wigren E; Graslund S; Proudman S; Lundberg IE; Limaye V
  • Journal article: RHEUMATOLOGY & AUTOIMMUNITY. 2022;2(2):57-68
    Galindo-Feria AS; Horuluoglu B; Lundberg IE
  • Article: SCIENTIFIC REPORTS. 2020;10(1):6078
    Horuluoglu BH; Kayraklioglu N; Tross D; Klinman D
  • Article: INFECTION AND IMMUNITY. 2019;87(12):e00742-e00719
    Kayraklioglu N; Horuluoglu B; Elango M; Klinman DM
  • Article: JOURNAL OF AUTOIMMUNITY. 2019;99:24-32
    Horuluoglu B; Bayik D; Kayraklioglu N; Goguet E; Kaplan MJ; Klinman DM
  • Article: ANIMAL. 2017;11(10):1791-1797
    Yalcin S; Gursel I; Bilgen G; Horuluoglu BH; Gucluer G; Izzetoglu GT
  • Article: ANIMAL. 2016;10(5):805-811
    Yalcin S; Gursel I; Bilgen G; Izzetoglu GT; Horuluoglu BH; Gucluer G

All other publications

  • Letter: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(12):1796-1797
    Leijding C; Kaewin S; Andreasson KM; Horuluoglu B; Galindo-Feria AS; Van Gompel E; Dastmalchi M; Gastaldello S; Alexanderson H; Lundberg IE; Andersson DC
  • Preprint: BIORXIV. 2024
    Leijding C; Andreasson K; Horuluoglu B; Galindo-Feria AS; Van Gompel E; Dastmalchi M; Gastaldello S; Alexanderson H; Lundberg I; Andersson D
  • Editorial comment: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2023;329(24):2130-2131
    Lundberg IE; Galindo-Feria AS; Horuluoglu B
  • Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:575
    Horuluoglu B; Galindo-Feria AS; Kumar R; Kozhukh G; Diaz-Boada JS; Ramskold D; Chemin K; Malmstrom V; Lundberg IE
  • Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:574
    Notarnicola A; Hellstrom C; Horuluoglu B; Preger C; Bonomi F; De Paepe B; De Bleecker J; Van der Kooi AJ; De Visser M; Sacconi S; Machado P; Badrising UA; Rietveld A; Pruijn G; Rothwell S; Lilleker JB; Chinoy H; Benveniste O; Svenungsson E; Idborg H; Jakobsson PJ; Nilsson P; Lundberg IE
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2023;75:4882-4884
    Gonzalez-Chapa JA; Albayda J; Horuluoglu B; Michailidou D; Macedo MB; Christopher-Stine L; Lundberg I; Lood C
  • Conference publication: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023;41(2):418
    Galindo-Feria AS; Lodin K; Horuluoglu B; Sarrafzadeh-Zargar S; Wigren E; Graslund S; Danielsson O; Mohammad AJ; Leonard D; Sjowall C; Husmark T; Hemberg M; Puksic S; Lappas T; Hanna B; Wahren-Herlenius M; Dastmalchi M; Lundberg IE
  • Conference publication: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023;41(2):428
    Argyriou A; Galindo-Feria A; Horuluoglu B; Diaz-Boada JS; Notarnicola A; Dani L; Van Vol-Lenhoven A; Ramskold D; Nennesmo I; Dastmalchi M; Lundberg IE; Diaz-Gallo LM; Chemin K
  • Review: FRONTIERS IN IMMUNOLOGY. 2022;13:866087
    Galindo-Feria AS; Notarnicola A; Lundberg IE; Horuluoglu B
  • Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:141
    Horuluoglu B; Feria ASG; Chemin K; Kozukh G; Dubnovitsky A; Malmstrom V; Lundberg IE
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2021;73:1414-1416
    Galindo-Feria AS; Horuluoglu B; Day J; Cerqueira C; Wigren E; Graslund S; Proudman S; Lundberg IE; Limaye V
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2021;73:3164-3165
    Horuluoglu B; Galindo-Feria AS; Chemin K; Kozhukh G; Dubnovitsky A; Malmstrom V; Lundberg IE
  • Conference publication: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2021;50:67
    Galindo-Feria AS; Horuluoglu B; Proudman S; Day J; Wigren E; Graslund S; Fernandes-Cerqueira C; Lundberg IE; Limaye V
  • Review: METHODS IN MOLECULAR BIOLOGY. 2021;2197:51-85
    Kayraklioglu N; Horuluoglu B; Klinman DM
  • Conference publication: JOURNAL OF IMMUNOLOGY. 2019;202(1)
    Horuluoglu BH; Bayik D; Kayraklioglu N; Goguet E; Blanco LP; Kaplan MJ; Klinman DM
  • Conference publication: JOURNAL OF IMMUNOLOGY. 2018;200(1)
    Horuluoglu BH; Bayik D; Goguet E; Tross D; Blanco LP; Kaplan MJ; Klinman DM

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