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Ängla Mantel

Ängla Mantel

Affiliated to Research | Docent
Visiting address: Maria Aspmans gata 30A, 17164 Solna
Postal address: K2 Medicin, Solna, K2 KEP Stephansson, 171 77 Stockholm

About me

  • I am an Associate Professor in Clinical Epidemiology, affiliated with the Clinical Epidemiology Division at the Department of Medicine, Solna. I combine research in reproductive epidemiology with clinical practice as a specialist in Obstetrics and Gynecology at Karolinska University Hospital.

    My research centers on the effects of chronic maternal conditions on pregnancy outcomes, neonatal and child health, the influence of delivery characteristics on neonatal well-being and maternal reproductive outcomes, and the interplay between women's reproductive health and cardiovascular health.

     

  • My work is supported by funding from the Strategic Research Area in Epidemiology and Biostatistics (SFOepi), the Swedish Heart and Lung Foundation, and Region Stockholm.

Research

  • Pregnancy involves extensive physiological adaptations to support the growing fetus and prepare for delivery. These changes make pregnancy and the postpartum period particularly vulnerable times for both mothers and their offspring, especially for women with pre-existing chronic conditions. Moreover, pregnancy provides a critical window for identifying individuals—both mothers and children—at risk of impaired short- and long-term health, as pregnancy and perinatal outcomes are closely linked to future health trajectories.

     

  • Understanding these associations is essential for antenatal care planning, preventing pregnancy complications, and implementing effective strategies to mitigate long-term health risks for women and children.

     

  • My research focuses on the impact of specific maternal conditions—such as eating disorders, acute hepatic porphyria, and heart disease—on pregnancy, perinatal, and child health. I am also actively involved in projects exploring how the mode of delivery influences child health, including the risk of neurodevelopmental disorders.

     

  • Additionally, I have a strong interest in women-specific risk factors for cardiovascular disease. My ongoing work examines various aspects of the relationship between women’s reproductive history and their cardiovascular disease risk, aiming to shed light on mechanisms and prevention strategies.

Articles

  • Article: JACC: HEART FAILURE. 2023;11(9):1216-1228
    Mantel A; Sandstrom A; Faxen J; Andersson DC; Razaz N; Cnattingius S; Stephansson O
  • Article: BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2023;130(9):1080-1086
    Berg P; Granfors M; Riese C; Mantel A
  • Article: JOURNAL OF INHERITED METABOLIC DISEASE. 2023;46(4):675-686
    Mantel A; Vassiliou D; Lissing M; Stephansson O; Wahlin S; Sardh E
  • Article: AMERICAN HEART JOURNAL. 2023;259:42-51
    Faxen J; Benson L; Mantel A; Savarese G; Hage C; Dahlstrom U; Askling J; Lun LH; Andersson DC
  • Article: PSYCHOLOGICAL MEDICINE. 2023;53(7):3056-3064
    Zhang T; Mantel A; Runeson B; Sidorchuk A; Ruck C; Stephansson O; Larsson H; Chang Z; Mataix-Cols D; Fernandez de la Cruz L
  • Article: JOURNAL OF SURGICAL RESEARCH. 2022;280:450-458
    Ernudd I; Alga A; Sandblom G; Dahlberg M; Mantel A
  • Article: JAMA NETWORK OPEN. 2022;5(1):e2143947
    Mantel A; Ortqvist AK; Hirschberg AL; Stephansson O
  • Article: ARTHRITIS CARE AND RESEARCH. 2021;73(5):658-665
    Holmqvist M; Mantel A; Wallberg-Jonsson S; James S; Jernberg T; Askling J
  • Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2021;224(4):380.e1-380.e13
    Mantel A; Ajne G; Wollmann CL; Stephansson O
  • Article: CLINICAL RHEUMATOLOGY. 2021;40(4):1321-1329
    Sodergren A; Askling J; Bengtsson K; Forsblad-d'Elia H; Jernberg T; Lindstrom U; Ljung L; Mantel A; Jacobsson LTH
  • Article: JAMA NETWORK OPEN. 2021;4(3):e210837
    Zhang T; Brander G; Mantel A; Kuja-Halkola R; Stephansson O; Chang Z; Larsson H; Mataix-Cols D; Fernandez de la Cruz L
  • Article: JAMA PSYCHIATRY. 2020;77(3):285-293
    Mantel A; Hirschberg AL; Stephansson O
  • Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(12):2017-2024
    Mantel A; Holmqvist M; Jernberg T; Wallberg-Jonsson S; Askling J
  • Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2017;69(10):1275-1285
    Mantel A; Holmqvist M; Andersson DC; Lund LH; Askling J
  • Article: JOURNAL OF PEDIATRIC UROLOGY. 2016;12(5):304.e1-304.e7
    Engberg GR; Mantel A; Fossum M; Nordenskjold A
  • Article: EUROPEAN HEART JOURNAL. 2015;36(48):3413-3422
    Mantel A; Holmqvist M; Jernberg T; Wallberg-Jonsson S; Askling J
  • Article: ARTHRITIS & RHEUMATOLOGY. 2015;67(11):2845-2854
    Mantel A; Holmqvist M; Nyberg F; Tornling G; Frisell T; Alfredsson L; Askling J
  • Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(4):541-546
    Holmqvist M; Gransmark E; Mantel A; Alfredsson L; Jacobsson LTH; Wallberg-Jonsson S; Askling J
  • Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2012;308(13):1350-1356
    Holmqvist ME; Neovius M; Eriksson J; Mantel A; Wallberg-Jonsson S; Jacobsson LTH; Askling J

All other publications

  • Book chapter: EATING DISORDERS. 2023;p. 923-937
    Mantel Ä; Lindén Hirschberg A
  • Book chapter: EATING DISORDERS. 2023;p. 603-622
    Mantel Ä; Hirschberg AL
  • Preprint: AUTHOREA. 2022
    Berg P; Granfors M; Riese C; Mantel Ä
  • Book chapter: EATING DISORDERS. 2022;p. 1-15
    Mantel Ä; Lindén Hirschberg A
  • Book chapter: EATING DISORDERS. 2022;p. 1-20
    Mantel Ä; Hirschberg AL
  • Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:341
    Sodergren A; Askling J; Bengtsson K; Forsblad-D'Elia H; Jernberg T; Lindstrom U; Ljung L; Mantel A; Jacobsson LT
  • Thesis / dissertation: 2017
    Mantel, Ängla
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2015;67
    Mantel A; Holmqvist M; Andersson D; Lund L; Askling J
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2015;67
    Mantel A; Holmqvist M; Jernberg T; Wallberg-Jonsson S; Askling J
  • Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:399
    Mantel A; Holmqvist M; Jernberg T; Wallberg-Jonsson S; Askling J
  • Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:125-126
    Mantel A; Holmqvist M; Asplund K; Wallberg-Jonsson S; Askling J
  • Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:632
    Mantel A; Holmqvist M; Nyberg F; Tornling G; Frisell T; Alfredsson L; Askling J
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2014;66:S1264
    Mantel A; Holmqvist M; Askling J; Lund L; Andersson D
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2014;66:S606
    Holmqvist M; Mantel A; Jernberg T; James S; Wallberg-Jonsson S; Askling J
  • Conference publication: ARTHRITIS & RHEUMATOLOGY. 2011;63(10):S449
    Holmqvist M; Mantel A; Jernberg T; Jacobsson LTH; Alfredsson L; James S; Askling J

Employments

  • Affiliated to Research, Department of Medicine, ̽»¨¾«Ñ¡, 2022-2025

Degrees and Education

  • Docent, Clinical Epidemiology, ̽»¨¾«Ñ¡, 2024
  • Degree Of Doctor Of Philosophy, Department of Medicine, Solna, ̽»¨¾«Ñ¡, 2017
  • Degree Of Master Of Science In Medicine, ̽»¨¾«Ñ¡, 2013

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