探花精选

Agneta Nordberg

Agneta Nordberg

Professor
Telephone: +46852482752
Visiting address: Blickag氓ngen 16, 14152 Huddinge
Postal address: H1 Neurobiologi, v氓rdvetenskap och samh盲lle, H1 Klinisk geriatrik Nordberg, 171 77 Stockholm
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About me

  • I obtained my MPharm, MD and PhD at Uppsala University, Uppsala, Sweden . After positions as Associate Professor and Senior Lecture in Pharmacology at Uppsala University I am since 1992 Professor in Clinical Neuroscience at 探花精选 and Senior Consultant at Theme Aging, Karolinska University Hospital, Stockholm.

    I have pioneered in field of cholinergic neurotransmission, nicotinic acetylcholine receptors as well as in the development of amyloid PET imaging, introducing the multi-tracer PET concept , evaluating drug mechanism of action and visualising reactive astrogliosis and tau pathology in patients with Alzheimer麓s disease (AD) and dementia disorders. My frontline research findings have been published in leading journals (500+ publications, H-index 79) and I have been PI for more than 15 clinical PET trials and received several prizes and rewards.

    I am leading a research team with a major focus on developing early diagnostic biomarkers and new drug targets in AD and other neurodegenerative proteinopathies.

    Academic honours, awards and prizes
    2020 Foundation for Research on Alzheimer/ European Grand Prix 2020 , 2017 Nominated by Swedish Research Council to Robert Bosch Stiftung Academia Net outstanding female academics , 2016 the Grand Silver Medal from 探花精选 for outstanding research, 2014 Queen Silvia prize for outstanding Alzheimer research , 2013 Wailet and Eric Forsgren prize for prominent Alzheimer research, 2006 Alois Alzheimer Award , 2004 de Leon Imaging Award in Alzheimer Research (Alz assoc USA), 2002 Life Achievement Award , ADRD conference, 2002 The Swedish Society of Medicine , Inga Sandeborg Alzheimer prize, 2001 Luigi Amaducci award in Alzheimer麓s disease, 1995 The Norage Kabi Pharmacia award 1 prize.

Research

  • Our research has a translational multimodal molecular imaging approach with the mission of further understanding of the time course and important interactions between different neurodegenerative pathophysiological processes in brain such as deposition of amyloid and tau, neuroinflammation especially reactive astrogliosis and synaptic dysfunction .

    We have a great interest in performing longitudinal brain PET studies in presymptomatic carriers of different forms of autosomal dominant AD as well as in Down麓s syndrome.

    We also want to relate pathological brain imaging and cognitive findings to fluid biomarkers for a further understanding of how early can we detect AD and other related neurodegenerative disorders and what are the implications for new promising treatment strategies.

    Furthermore, we have ongoing studies aiming to develop new selective PET tracers for alpha-synuclein, 4R tau, as well as alpha 7 nicotinic acetylcholine receptors, the latter as a synaptic marker.

Articles

  • Article: EBIOMEDICINE. 2025;112:105504
    Bluma M; Chiotis K; Bucci M; Savitcheva I; Matton A; Kivipelto M; Jeromin A; De Santis G; Di Molfetta G; Ashton NJ; Blennow K; Zetterberg H; Nordberg A
  • Article: MOLECULAR PSYCHIATRY. 2025;30(2):587-599
    Ioannou K; Bucci M; Tzortzakakis A; Savitcheva I; Nordberg A; Chiotis K
  • Article: ALZHEIMERS & DEMENTIA. 2025;21(2):e14409
    Scarpa M; Vallera E; Auselle-Bosch S; Rocha FM; Mercan BE; Roy A; Nordberg A; Kumar A
  • Article: JOURNAL OF NUCLEAR MEDICINE. 2025;66(1):110-116
    Collij LE; Bischof GN; Altomare D; Bader I; Battle M; Garcia DV; Alves IL; Wolz R; Gismondi R; Stephens A; Walker Z; Scheltens P; Nordberg A; Gispert JD; Drzezga A; Perissinotti A; Morbelli S; Buckley C; Garibotto V; Frisoni GB; Farrar G; Barkhof F
  • Article: JAMA NEUROLOGY. 2024;81(12):1304-1311
    Dubois B; Villain N; Schneider L; Fox N; Campbell N; Galasko D; Kivipelto M; Jessen F; Hanseeuw B; Boada M; Barkhof F; Nordberg A; Froelich L; Waldemar G; Frederiksen KS; Padovani A; Planche V; Rowe C; Bejanin A; Ibanez A; Cappa S; Caramelli P; Nitrini R; Allegri R; Slachevsky A; de Souza LC; Bozoki A; Widera E; Blennow K; Ritchie C; Agronin M; Lopera F; Delano-Wood L; Bombois S; Levy R; Thambisetty M; Georges J; Jones DT; Lavretsky H; Schott J; Gatchel J; Swantek S; Newhouse P; Feldman HH; Frisoni GB
  • Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51(13):3960-3977
    Sobek J; Li J; Combes BF; Gerez JA; Henrich MT; Geibl FF; Nilsson PR; Shi K; Rominger A; Oertel WH; Nitsch RM; Nordberg A; Agren H; Ni R
  • Article: BRAIN COMMUNICATIONS. 2024;6(6):fcae426
    Wheatley SH; Mohanty R; Poulakis K; Levin F; Muehlboeck JS; Nordberg A; Grothe MJ; Ferreira D; Westman E
  • Article: LAKARTIDNINGEN. 2024;121:23083
    Granholm A-C; Larsson L; 脰hman F; Zetterberg H; Hansson O; Eriksdotter M; Kern S; Nordberg A
  • Article: NEUROLOGY. 2024;103(1):e209419
    Mastenbroek SE; Sala A; Vallez Garcia D; Shekari M; Salvado G; Lorenzini L; Pieperhoff L; Wink AM; Lopes Alves I; Wolz R; Ritchie C; Boada M; Visser PJ; Bucci M; Farrar G; Hansson O; Nordberg AK; Ossenkoppele R; Barkhof F; Gispert JD; Rodriguez-Vieitez E; Collij LE
  • Article: ALZHEIMERS & DEMENTIA. 2024;20(5):3429-3441
    Bollack A; Collij LE; Garcia DV; Shekari M; Altomare D; Payoux P; Dubois B; Grau-Rivera O; Boada M; Marquie M; Nordberg A; Walker Z; Scheltens P; Scholl M; Wolz R; Schott JM; Gismondi R; Stephens A; Buckley C; Frisoni GB; Hanseeuw B; Visser PJ; Vandenberghe R; Drzezga A; Yaqub M; Boellaard R; Gispert JD; Markiewicz P; Cash DM; Farrar G; Barkhof F
  • Article: ALZHEIMERS & DEMENTIA. 2024;20(4):2589-2605
    Kumar A; Scarpa M; Nordberg A
  • Journal article: NEUROLOGY. 2024;102(6):e208053
    Hoenig M; Altomare D; Caprioglio C; Collij L; Barkhof F; Van Berckel B; Scheltens P; Farrar G; Battle MR; Theis H; Giehl K; Bischof GN; Garibotto V; Molinuevo JLL; Grau-Rivera O; Delrieu J; Payoux P; Demonet JF; Nordberg AK; Savitcheva I; Walker Z; Edison P; Stephens AW; Gismondi R; Jessen F; Buckley CJ; Gispert JD; Frisoni GB; Drzezga A
  • Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(2):328-336
    Fontana IC; Kumar A; Okamura N; Nordberg A
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S10)
    Scarpa M; Kumar A; Nordberg AK
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S17)
    Nordberg AK; Chiotis K; Fontana IC; Malarte M; Gillberg P; Bucci M; Bluma M; Kumar A
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S10)
    Rocha FM; Nordberg AK; Kumar A
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S10)
    Malarte M; Gillberg P; Kumar A; Nordberg AK
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S17)
    R茅gy M; Quenon L; Collij LE; Garc铆a DV; G茅rard T; Frisoni G; Scheltens P; Sch枚ll M; Vandenberghe R; Boada M; Marqui茅 M; Payoux P; Nordberg AK; Kivipelto M; Walker Z; Dubois B; Boutoleau鈥怋retonni猫re C; Pasquier F; Dugravot A; Gabelle A; Visser PJ; Grau鈥怰ivera O; Martinez鈥怢age P; Ritchie CW; Wolz R; Farrar G; Lhommel R; Barkhof F; Dumurgier J; Hanseeuw BJ
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S17)
    Bollack A; Collij LE; Garc铆a DV; Shekari M; Altomare D; Payoux P; Dubois B; Grau鈥怰ivera O; Rovira MB; Nordberg AK; Walker Z; Scheltens P; Sch枚ll M; Wolz R; Schmidt ME; Gismondi R; Stephens AW; Buckley C; Frisoni GB; Hanseeuw BJ; Visser PJ; Vandenberghe R; Drzezga A; Yaqub M; Boellaard R; Markiewicz PJ; Cash DM; Farrar G; Gispert JD; Barkhof F; consortium TA
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S18)
    Zeyen P; Sannemann L; Escher C; Maier F; Rostamzadeh A; Drzezga A; Giehl K; Bischof GN; H枚nig MC; Altomare D; Garibotto V; Barkhof F; Scheltens P; van Berckel BNM; Collij LE; Molinuevo JL; Grau鈥怰ivera O; Gispert JD; Delrieu J; Payoux P; Nordberg AK; Savitcheva I; Walker Z; Edison P; Demonet J; Stephens AW; Gismondi R; Farrar G; Frisoni GB; Jessen F
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All other publications

  • Preprint: RESEARCH SQUARE. 2024
    Wheatley S; Mohanty R; Poulakis K; Levin F; Muehlboeck J-S; Nordberg A; Grothe M; Ferreira D; Westman E
  • Preprint: MEDRXIV. 2024
    Collij LE; Bischof GN; Altomare D; Bader I; Battle M; Garc铆a DV; Alves IL; Wolz R; Gismondi R; Stephens A; Walker Z; Scheltens P; Nordberg A; Gispert JD; Drzezga A; Perissinotti A; Morbelli S; Buckley C; Garibotto V; Frisoni GB; Farrar G; Barkhof F
  • Editorial comment: LANCET NEUROLOGY. 2024;23(5):453-454
    Nordberg A
  • Preprint: BIORXIV. 2024
    Maschio CA; Wang J; Maheshwari U; Keller A; Rominger A; Konietzko U; Nordberg A; Hock C; Nitsch RM; Ni R
  • Editorial comment: THE LANCET. HEALTHY LONGEVITY. 2024;5(2):e88-e89
    Bucci M; Nordberg A
  • Corrigendum: MOLECULAR PSYCHIATRY. 2024;29(1):38
    Malarte M-L; Gillberg P-G; Kumar A; Bogdanovic N; Lemoine L; Nordberg A
  • Review: CELLS. 2023;12(11):1469
    Fontana IC; Scarpa M; Malarte M-L; Rocha FM; Auselle-Bosch S; Bluma M; Bucci M; Chiotis K; Kumar A; Nordberg A
  • Review: NATURE REVIEWS NEUROLOGY. 2023;19(5):278-288
    Fontana IC; Kumar A; Nordberg A
  • Corrigendum: ALZHEIMERS RESEARCH & THERAPY. 2023;15(1):80
    Mohanty R; Ferreira D; Nordberg A; Westman E
  • Editorial comment: NEUROCHEMICAL RESEARCH. 2023;48(4):1009-1014
    Nordberg A; Semyanov A; Parpura V; Zorec R
  • Preprint: BIORXIV. 2023
    Sobek J; Li J; Combes BF; Gerez JA; Nilsson PK; Henrich MT; Geibl FF; Shi K; Rominger A; Oertel WH; Nitsch RM; Nordberg A; 脜gren H; Riek R; Ni R
  • Review: JOURNAL OF NEUROCHEMISTRY. 2023;164(3):309-324
    Kumar A; Fontana IC; Nordberg A
  • Conference publication: ACTA PHYSIOLOGICA. 2023;239
    Nordberg A
  • Review: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2022;10(1):166
    Ferreira D; Mohanty R; Murray ME; Nordberg A; Kantarci K; Westman E
  • Preprint: BIORXIV. 2022
    Yang Y; Zhang W; Murzin AG; Schweighauser M; Huang M; L枚vestam S; Peak-Chew SY; Saito T; Saido TC; Macdonald J; Lavenir I; Ghetti B; Graff C; Kumar A; Nordberg A; Goedert M; Scheres SHW
  • Editorial comment: SCIENCE TRANSLATIONAL MEDICINE. 2022;14(659):eabm8302
    Zimmer ER; Pascoal TA; Rosa-Neto P; Nordberg A; Pellerin L
  • Review: FRONTIERS IN NEUROLOGY. 2022;13:1063598
    Collij LE; Farrar G; Garcia DV; Bader I; Shekari M; Lorenzini L; Pemberton H; Altomare D; Pla S; Loor M; Markiewicz P; Yaqub M; Buckley C; Frisoni GB; Nordberg A; Payoux P; Stephens A; Gismondi R; Visser PJ; Ford L; Schmidt M; Birck C; Georges J; Mett A; Walker Z; Boada M; Drzezga A; Vandenberghe R; Hanseeuw B; Jessen F; Scholl M; Ritchie C; Lopes Alves I; Gispert JD; Barkhof F; AMYPAD C
  • Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2022;49(SUPPL 1):S49-S50
    Altomare D; Barkhof F; Caprioglio C; Collij LE; Scheltens P; van Berckel BNM; Alves IL; Berkhof J; van Maurik IS; Garibotto V; Moro C; Delrieu J; Molinuevo J; Grau-Rivera O; Gispert J; Drzezga A; Jessen F; Nordberg A; Walker Z; Demonet J; Gismondi R; Farrar G; Stephens AW; Frisoni GB
  • Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2022;29:148
    Hoenig M; Caprioglio C; Collij L; Frisoni G; Barkhof F; Farrar G; Scheltens P; Delrieu J; Molinuevo J; Grau-Rivera O; Walker Z; Nordberg A; Demonet J; Stephens A; Battle M; Buckley C; Gispert J; Jessen F; Altomare D; Drzezga A
  • Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022;42(1_SUPPL):280
    Cash D; Singh N; Turkheimer F; Nordberg A
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Grants

  • Swedish Research Council
    1 January 2024 - 31 December 2027
  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • Swedish Research Council
    1 January 2018 - 31 December 2020
  • Swedish Research Council
    1 December 2017 - 31 December 2022
  • Swedish Research Council
    1 December 2017 - 31 December 2022
  • Swedish Research Council
    1 January 2017 - 31 December 2020
  • Swedish Research Council
    1 January 2017 - 31 December 2020
  • Swiss National Science Foundation
    1 September 2016 - 31 July 2017
  • New biomarkers in early diagnosis and treatment of AD
    Swedish Foundation for Strategic Research
    1 January 2015 - 31 December 2019
  • Swedish Research Council
    1 January 2014 - 31 December 2017
  • Swedish Research Council
    1 January 2013 - 31 December 2016
  • Swedish Research Council
    1 January 2011 - 31 December 2013

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