Endocrinology Unit with the Lipid laboratory and Clinical Research Center
At the unit we study the role of lipid metabolism in cardiometabolic diseases, in order to develop treatments for common national diseases such as obesity and lipid disorders. The unit consists of one wet laboratory and one clinical research center with four independent research groups. The groups lead their own projects but with a continuous collaboration within the unit.
Endocrinology unit
As an integral part of the Department of Medicine, Huddinge, the Endocrinology unit is studying the role of lipid metabolism in cardiometabolic diseases. Professor Mikael Ryd茅n is heading the Unit of Endocrinology with the Lipid laboratory and Clinical Research Center.
Lipid Laboratory and Clinical Research Center
The unit is comprised by one fully equipped wet laboratory, called the Lipid laboratory, located in the at KI Campus Flemingsberg and a Clinical Research Center at the adjacent Karolinska University Hospital, Huddinge. The Clinical Research Center is part of a core facility within the Strategic Research Programme in Diabetes.
The Unit of Endocrinology with the Lipid laboratory is world leading in the studies of human white adipose tissue, with ongoing local, national and international collaborations with research groups conducting metabolic research.
Studies of white adipose tissue
Our scientific mission is to study role of human white adipose tissue in common cardiometabolic diseases. We have a long-standing record as one of the world-leading groups in the field of human adipose tissue research. Altogether, the unit consists of four independent groups led by principal investigators with specific areas of interest, senior researchers, post-doctoral fellows, PhD students and technical staff.
For more information about the research conducted at the Endocrinology Unit and the Lipid Laboratory and Clinical Research Center, please visit each research group page.
Clinical research studies
1). (inclusion 2018-ongoing)
2). (inclusion 2017-ongoing)
3). (inclusion 2015-ongoing)
4). (inclusion 2011-2014)
5). (inclusion 2014-2016)
6). Bone marrow transplant trial (inclusion 2010-2012)
7).
8). Cancer cachexi (inclusion 2004-2005)
Cardio Metabolic Unit (CMU)
The Cardio Metabolic Unit (CMU) is a research constellation, driving innovative and implementable research and education, closely integrated with specialized health care. In line with its translational approach, CMU is linked to the Department of Medicine in Huddinge and Department of Laboratory Medicine at Campus Flemingsberg, 探花精选.
Cardio Metabolic Unit CMU at KI research networks
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is academic specialist center for clinical investigation and treatment in the areas of andrology, sexual medicine and trans medicine. The center belongs to Karolinska University Hospital, but the research is conducted in a variety of fields in collaboration with the Endocrinology unit at the Department of Medicine, Huddinge at 探花精选, among other partners.
Contact:
- Med Dr, psychologist.
- Mats Holmberg, Med Dr, Chief physician.
Head of Unit
Mikael Ryden
Professor/Senior PhysicianMikael Ryd茅n is Head of the Endocrinology unit and Co-lead of the research group Ryd茅n & Mejhert lab together with .
Mikael is a senior consultant in endocrinology and Professor of adipose tissue research. He has spent the last 25 years of his career focusing on studies of white adipose tissue.
Unit administrator
Lena Lindberg
AdministratorAddress
Lipid Laboratory, Medicinaren 25, NEO, 7th Floor, H盲lsov盲gen 7 C, Campus Flemingsberg, Huddinge.
Research groups
Jan Bolinder research group
Ingrid Dahlman research group
Genetic studies of adipose tissue, obesity and insulin resistance
Alastair Kerr research group
Long noncoding RNA in the adipocyte
Jurga Laurencikiene research group
Regulation of transcription in adipose tissue
Ryd茅n & Mejhert research group
Mikael Ryd茅n & Niklas Mejhert lab
Paul Petrus research group
Preventell
Selected publications
Arner P, Bernard S, Appelsved L, Fu KY, Andersson DP, Salehpour M, et al. Nat. Med. 2019 09;25(9):1385-1389
Ryd茅n M, Petrus P, Andersson DP, Medina-G贸mez G, Escasany E, Corrales Cord贸n P, et al
J. Intern. Med. 2019 May;285(5):578-588
- . Petrus P, Mejhert N, Corrales P, Lecoutre S, Li Q, Maldonado E, et al. Cell Rep 2018 10;25(3):551-560.e5
Andersson DP, Dahlman I, Eriksson Hogling D, B盲ckdahl J, Toft E, Qvisth V, N盲slund E, Thorell A, Ryd茅n M, Arner P
J Intern Med 2019 01;285(1):92-101
- .
Arner P, Andersson DP, B盲ckdahl J, Dahlman I, Ryd茅n M. Cell Metab. 2018 Jul;28(1):45-54.e3
- .
Gao H, Kerr A, Jiao H, Hon CC, Ryd茅n M, Dahlman I, et al. EBioMedicine 2018 Apr;30():248-260
- .
Spalding KL, Bernard S, N盲slund E, Salehpour M, Possnert G, Appelsved L, et al. Nat Commun 2017 05;8():15253
- .
Ryd茅n M, Hrydziuszko O, Mileti E, Raman A, Bornholdt J, Boyd M, et al. Cell Rep 2016 08;16(9):2317-26
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Ryd茅n M, Uzunel M, H氓rd JL, Borgstr枚m E, Mold JE, Arner E, et al. Cell Metab. 2015 Sep;22(3):408-1
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Gao H, Mejhert N, Fretz JA, Arner E, Lorente-Cebri谩n S, Ehrlund A, et al. Cell Metab. 2014 Jun;19(6):981-92