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Ulrika Marklund

Ulrika Marklund

Senior Forskare | Docent
E-postadress: ulrika.marklund@ki.se
Telefon: +46852483519
ö: Solnavägen 9, 6C, 17177 Stockholm
Postadress: C2 Medicinsk biokemi och biofysik, C2 Molekylär neurobiologi Marklund, 171 77 Stockholm

Om mig

  • My major research interest has always been centered around the development and function of neural cell types. During my PhD at the Department of Cell and Molecular Biology at KI, I studied transcriptional determinants of specific neuronal identities including the dopaminergic and serotonergic neurons of the brain. I thereafter transitioned my research focus to the “Brain in the gut” – the Enteric Nervous System, during a postdoc at National Institute for Medical Research in Mill Hill, London, UK. Since 2013,   I have led my own research group at the Department of Medical Biochemistry and Biophysics. 

     

    1996-2001 Master in Molecular Biology, Umeå University
    1999-2000 ERASMUS exchange year, University of Manchester, UK
    2002-2008 PhD candidate, Dept Cell and Molecular Biology, Karolinska Institutet
    2009-2010 Postdoc, National Institute for Medical Research; Mill Hill,  London, UK

Forskningsbeskrivning

  • My research team focuses on neural cell diversity in the Enteric Nervous System (ENS). By determining the variety of ENS cell subtypes, the functions they normally serve and their developmental specification we aim to improve diagnostic and therapeutic principles for gut disorders. The lab addresses these basic but critical questions by transcriptome analysis coupled with viral-based activity/gene manipulations using the mouse model.

Artiklar

  • Article: NATURE NEUROSCIENCE. 2024;27(12):2267-2268
    Ernfors P; Castelo-Branco G; Uhlen P; Linnarsson S; Marklund U; Hjerling-Leffler J; Dagliyan O
  • Article: BIOMOLECULES. 2023;13(7):1063
    Herath M; Cho E; Marklund U; Franks AE; Bornstein JC; Hill-Yardin EL
  • Article: STEM CELL REPORTS. 2021;16(11):2718-2735
    Oosterveen T; Garcao P; Moles-Garcia E; Soleilhavoup C; Travaglio M; Sheraz S; Peltrini R; Patrick K; Labas V; Combes-Soia L; Marklund U; Hohenstein P; Panman L
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(6):145837
    Le T-L; Galmiche L; Levy J; Suwannarat P; Hellebrekers DM; Morarach K; Boismoreau F; Theunissen TEJ; Lefebvre M; Pelet A; Martinovic J; Gelot A; Guimiot F; Calleroz A; Gitiaux C; Hully M; Goulet O; Chardot C; Drunat S; Capri Y; Bole-Feysot C; Nitschke P; Whalen S; Mouthon L; Babcock HE; Hofstra R; de Coo IFM; Tabet A-C; Molina TJ; Keren B; Brooks A; Smeets HJM; Marklund U; Gordon CT; Lyonnet S; Amiel J; Bondurand N
  • Article: NATURE NEUROSCIENCE. 2021;24(1):34-46
    Morarach K; Mikhailova A; Knoflach V; Memic F; Kumar R; Li W; Ernfors P; Marklund U
  • Article: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2019;12:6
    Kastriti ME; Kameneva P; Kamenev D; Dyachuk V; Furlan A; Hampl M; Memic F; Marklund U; Lallemend F; Hadjab S; Calvo-Enrique L; Ernfors P; Fried K; Adameyko I
  • Article: CELL. 2018;174(4):999-1014.e22
    Zeisel A; Hochgerner H; Lonnerberg P; Johnsson A; Memic F; van der Zwan J; Haring M; Braun E; Borm LE; La Manno G; Codeluppi S; Furlan A; Lee K; Skene N; Harris KD; Hjerling-Leffler J; Arenas E; Ernfors P; Marklund U; Linnarsson S
  • Article: ELIFE. 2018;7:e34465
    Kaucka M; Petersen J; Tesarova M; Szarowska B; Kastriti ME; Xie M; Kicheva A; Annusver K; Kasper M; Symmons O; Pan L; Spitz F; Kaiser J; Hovorakova M; Zikmund T; Sunadome K; Matise MP; Wang H; Marklund U; Abdo H; Ernfors P; Maire P; Wurmser M; Chagin AS; Fried K; Adameyko I
  • Article: GASTROENTEROLOGY. 2018;154(3):624-636
    Memic F; Knoflach V; Morarach K; Sadler R; Laranjeira C; Hjerling-Leffler J; Sundstrom E; Pachnis V; Marklund U
  • Article: SCIENCE. 2017;357(6346):46
    Furlan A; Dyachuk V; Kastriti ME; Calvo-Enrique L; Abdo H; Hadjab S; Chontorotzea T; Akkuratova N; Usoskin D; Kamenev D; Petersen J; Sunadome K; Memic F; Marklund U; Fried K; Topilko P; Lallemend F; Kharchenko PV; Ernfors P; Adameyko I
  • Article: JOURNAL OF NEUROSCIENCE. 2016;36(15):4339-4350
    Memic F; Knoflach V; Sadler R; Tegerstedt G; Sundstrom E; Guillemot F; Pachnis V; Marklund U
  • Article: SCIENCE. 2014;345(6192):82-87
    Dyachuk V; Furlan A; Shahidi MK; Giovenco M; Kaukua N; Konstantinidou C; Pachnis V; Memic F; Marklund U; Mueller T; Birchmeier C; Fried K; Ernfors P; Adameyko I
  • Article: STEM CELLS AND DEVELOPMENT. 2014;23(1):5-15
    Marklund U; Alekseenko Z; Andersson E; Falci S; Westgren M; Perlmann T; Graham A; Sundstrom E; Ericson J
  • Article: DEVELOPMENT. 2010;137(23):4051-4060
    Lek M; Dias JM; Marklund U; Uhde CW; Kurdija S; Lei Q; Sussel L; Rubenstein JL; Matise MP; Arnold H-H; Jessell TM; Ericson J
  • Article: JOURNAL OF CELL SCIENCE. 2010;123(17):2931-2942
    Hansson EM; Lanner F; Das D; Mutvei A; Marklund U; Ericson J; Farnebo F; Stumm G; Stenmark H; Andersson ER; Lendahl U
  • Article: DEVELOPMENT. 2010;137(3):437-445
    Marklund U; Hansson EM; Sundstrom E; de Angelis MH; Przemeck GKH; Lendahl U; Muhr J; Ericson J
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(18):7613-7618
    Friling S; Andersson E; Thompson LH; Jonssonc ME; Hebsgaard JB; Nanou E; Alekseenko Z; Marklund U; Kjellander S; Volakakis N; Hovatta O; El Manira A; Bjorklund A; Perlmann T; Ericson J
  • Article: CELL. 2006;124(2):393-405
    Andersson E; Tryggvason U; Deng QL; Friling S; Alekseenko Z; Robert B; Perlmann T; Ericson J
  • Article: NATURE NEUROSCIENCE. 2003;6(9):933-938
    Ding YQ; Marklund U; Yuan WL; Yin J; Wegman L; Ericson J; Deneris E; Johnson RL; Chen ZF

Alla övriga publikationer

  • Editorial comment: NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. 2022;19(2):85-86
    Marklund U
  • Preprint: BIORXIV. 2020
    Morarach K; Mikhailova A; Knoflach V; Memic F; Kumar R; Li W; Ernfors P; Marklund U
  • Doctoral thesis: 2008
    Marklund U

Forskningsbidrag

  • Swedish Research Council
    1 January 2023 - 31 December 2027
  • Swedish Research Council
    1 January 2021 - 31 December 2024
  • Knut and Alice Wallenberg Foundation
    1 January 2020
  • Swedish Research Council
    1 January 2017 - 31 December 2020
  • Swedish Research Council
    1 January 2013 - 31 December 2016

ԲäԾԲ

  • Senior Forskare, Medicinsk biokemi och biofysik, ̽ѡ, 2022-

Examina och utbildning

  • Docent, Neurovetenskap, ̽ѡ, 2024
  • Filosofie Doktorsexamen, Institutionen för cell- och molekylärbiologi, ̽ѡ, 2008

Nyheter från KI

Kalenderhändelser från KI