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Margareta Wilhelm

Margareta Wilhelm

Senior Forskare | Docent
Telefon: +46852482823
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: Solnavägen 9, B7, 17165 Solna
Postadress: C1 Mikrobiologi, tumör- och cellbiologi, C1 Tumor Biology Wilhelm, 171 77 Stockholm

Om mig

  • Margareta Wilhelm är docent i tumörbiologi vid institutionen för mikrobiologi, tumör- och cellbiologi. Hon tog en magisterexamen i molekylärbiologi vid UmeÃ¥ universitet och avlade sin doktorsexamen i experimentell onkologi 2003 vid ̽»¨¾«Ñ¡, följt av postdoktoral utbildning vid Campbell Family Cancer Research Institute i Toronto, Kanada. Dr. Wilhelm har tilldelats en forskarassistenttjänst frÃ¥n VetenskapsrÃ¥det,  

  • Young Investigator Award frÃ¥n Cancerfonden, samt en fakultetsfinansierad seniorforskartjänst vid ̽»¨¾«Ñ¡. 
  • För närvarande innehar hon en högre forskartjänst inom barncancerforskning frÃ¥n Barncancerfonden.

Forskningsbeskrivning

  • Forskargruppen fokuserar pÃ¥ att förstÃ¥ mekanismer som reglerar tumörinitiering och -progression med ett särskilt intresse för tumörmikromiljön och infiltrerande immunceller. Vi använder transgena modeller, cellulär reprogrammering, stamceller, och organoider för att modellera tumörutveckling.

Undervisning

  • Docent in Tumor Biology
    Program Director Research education program in Tumor Biology and Oncology
    (FoTO)
    Study Director Elective track in Tumor Biology Biomedicine Master program
    Course Organizer and Teacher Biomedicine Master program

Artiklar

  • Journal article: NEURO-ONCOLOGY. 2024;:noae210
    van Bree N; Oppelt A-S; Lindstroem S; Zhou L; Boutin L; Coyle B; Swartling FJ; Johnsen JI; Braeutigam L; Wilhelm M
  • Article: NEURO-ONCOLOGY. 2024;26(9):1685-1699
    Zhou L; van Bree N; Boutin L; Ryu J; Moussaud S; Liu M; Otrocka M; Olsson M; Falk A; Wilhelm M
  • Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2022;79(10):535
    Maeso-Alonso L; Alonso-Olivares H; Martinez-Garcia N; Lopez-Ferreras L; Villoch-Fernandez J; Puente-Santamaria L; Colas-Algora N; Fernandez-Corona A; Lorenzo-Marcos ME; Jimenez B; Holmgren L; Wilhelm M; Millan J; del Peso L; Claesson-Welsh L; Marques MM; Marin MC
  • Article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2022;9:823195
    Grinkevich VV; Vema A; Fawkner K; Issaeva N; Andreotti V; Dickinson ER; Hedstrom E; Spinnler C; Inga A; Larsson L-G; Karlen A; Wilhelm M; Barran PE; Okorokov AL; Selivanova G; Zawacka-Pankau JE
  • Article: CANCERS. 2021;13(21):5493
    Milosevic J; Fransson S; Gulyas M; Olsen TK; Gallo-Oller G; Treis D; Elfman LHM; Wilhelm M; Martinsson T; Baryawno N; Kogner P; Johnsen JI
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(10):e2017089118
    Wolfsberger J; Sakil HAM; Zhou L; van Bree N; Baldisseri E; Ferreira SDS; Zubillaga V; Stantic M; Fritz N; Hartman J; Rolny C; Wilhelm MT
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(33):20127-20138
    Susanto E; Navarro AM; Zhou L; Sundstrom A; van Bree N; Stantic M; Moslem M; Tailor J; Rietdijk J; Zubillaga V; Huebner J-M; Weishaupt H; Wolfsberger J; Alafuzoff I; Nordgren A; Magnaldo T; Siesjo P; Johnsen JI; Kool M; Tammimies K; Darabi A; Swartling FJ; Falk A; Wilhelm M
  • Article: CELL DEATH AND DISEASE. 2020;11(1):52
    Navarro AM; Pronk RJ; van der Geest AT; Oliynyk G; Nordgren A; Arsenian-Henriksson M; Falk A; Wilhelm M
  • Article: CELL DEATH AND DISEASE. 2019;10(9):663
    Das I; Wilhelm M; Hoiom V; Marquez RF; Svedman FC; Hansson J; Tuominen R; Brage SE
  • Article: STEM CELL RESEARCH. 2019;34:101356
    Navarro AM; Day K; Kogner P; Wilhelm M; Falk A
  • Article: ONCOGENE. 2018;37(27):3729-3739
    Stantic M; Wolfsberger J; Sakil HAM; Wilhelm MT
  • Article: CELLULAR ONCOLOGY (DORDRECHT). 2017;40(6):631-638
    Sakil HAM; Stantic M; Wolfsberger J; Brage SE; Hansson J; Wilhelm MT
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(1):220-225
    Stantic M; Sakil HAM; Zirath H; Fang T; Sanz G; Fernandez-Woodbridge A; Marin A; Susanto E; Mak TW; Henriksson MA; Wilhelm MT
  • Article: CELL DEATH AND DISEASE. 2014;5(10):e1484
    Kostecka A; Sznarkowska A; Meller K; Acedo P; Shi Y; Sakil HAM; Kawiak A; Lion M; Krolicka A; Wilhelm M; Inga A; Zawacka-Pankau J
  • Article: EMBO REPORTS. 2014;15(4):embr201337424-391
    Zinin N; Adameyko I; Wilhelm M; Fritz N; Uhlen P; Ernfors P; Henriksson MA
  • Article: CELL DEATH AND DIFFERENTIATION. 2013;20(2):293-301
    Tomasini R; Secq V; Pouyet L; Thakur AK; Wilhelm M; Nigri J; Vasseur S; Berthezene P; Calvo E; Melino G; Mak TW; Iovanna JL
  • Article: PHYSICS IN MEDICINE AND BIOLOGY. 2012;57(22):7431-7441
    Lundstrom U; Larsson DH; Burvall A; Scott L; Westermark UK; Wilhelm M; Henriksson MA; Hertz HM
  • Article: ONCOGENE. 2010;29(49):6442-6451
    Rokaeus N; Shen J; Eckhardt I; Bykov VJN; Wiman KG; Wilhelm MT
  • Article: GENES & DEVELOPMENT. 2010;24(6):549-560
    Wilhelm MT; Rufini A; Wetzel MK; Tsuchihara K; Inoue S; Tomasini R; Itie-Youten A; Wakeham A; Arsenian-Henriksson M; Melino G; Kaplan DR; Miller FD; Mak TW
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(37):15756-15761
    Vilborg A; Glahder JA; Wilhelm MT; Bersani C; Corcoran M; Mahmoudi S; Rosenstierne M; Grander D; Farnebo M; Norrild B; Wiman KG
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(3):797-802
    Tomasini R; Tsuchihara K; Tsuda C; Lau SK; Wilhelm M; Rufini A; Tsao M-S; Iovanna JL; Jurisicova A; Melino G; Mak TW
  • Article: GENES & DEVELOPMENT. 2008;22(19):2677-2691
    Tomasini R; Tsuchihara K; Wilhelm M; Fujitani M; Rufini A; Cheung CC; Khan F; Itie-Youten A; Wakeham A; Tsao M-S; Iovanna JL; Squire J; Jurisica I; Kaplan D; Melino G; Jurisicova A; Mak TW
  • Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(1):64-72
    Hall HTL; Wilhelm MT; Saibil SD; Mak TW; Flavell RA; Ohashi PS
  • Article: FEBS LETTERS. 2002;524(1-3):69-72
    Wilhelm MT; Méndez-Vidal C; Wiman KG
  • Article: NUCLEIC ACIDS RESEARCH (NAR). 2002;30(9):1991-1996
    Méndez-Vidal C; Wilhelm MT; Hellborg F; Qian W; Wiman KG
  • Article: ONCOGENE. 2001;20(39):5466-5474
    Hellborg F; Qian W; Mendez-Vidal C; Asker C; Kost-Alimova M; Wilhelm M; Imreh S; Wiman KG
  • Visa fler

Alla övriga publikationer

  • Preprint: BIORXIV. 2024
    Boutin L; Liu M; Merville JD; Bedoya-Reina O; Wilhelm MT
  • Preprint: BIORXIV. 2024
    van Bree N; Oppelt A-S; Lindström S; Zhou L; Boutin L; Johnsen JI; Bräutigam L; Wilhelm M
  • Preprint: BIORXIV. 2024
    Zhou L; van Bree N; Boutin L; Moussaud S; Otrocka M; Falk A; Wilhelm M
  • Review: CANCERS. 2022;14(20):5009
    van Bree NFHN; Wilhelm M
  • Preprint: BIORXIV. 2022
    Maeso-Alonso L; Alonso-Olivares H; Martínez-García N; Lopez-Ferreras L; Villoch-Fernández J; Puente-Santamaría L; Colas-Algora N; Fernández-Corona A; Lorenzo-Marcos ME; Jiménez B; Holmgren L; Wilhelm M; Millan J; del Peso L; Claesson-Welsh L; Marques MM; Marin MC
  • Preprint: BIORXIV. 2021
    Grinkevich VV; Aparna V; Fawkner K; Issaeva N; Andreotti V; Dickinson ER; Hedström E; Spinnler C; Inga A; Larsson L-G; Karlén A; Wilhelm M; Barran PE; Okorokov AL; Selivanova G; Zawacka-Pankau JE
  • Preprint: BIORXIV. 2020
    Milosevic J; Fransson S; Gulyas M; Gallo-Oller G; Olsen T; Treis D; Wickström M; Elfman LHM; Sveinbjornsson B; Hertwig F; Bartenhagen C; Reinsbach S; Wilhelm M; Abel F; Javanmardi N; Thankaswamy-Kosalai S; Eissler N; Kock A; Shi Y; Tanino K; Hehir-Kwa J; Mensenkamp A; Tytgat GAM; Kanduri C; Holmberg J; Gisselsson D; Molenaar J; Jongmans M; Fischer M; Kool M; Sakaguchi K; Baryawno N; Martinsson T; Johnsen JI; Kogner P
  • Meeting abstract: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(9):s298
    Das I; Chen H; Maddalo G; Wilhelm M; Tuominen R; Hoiom V; Hansson J; Davies M; Brage S
  • Review: CELL DEATH DISCOVERY. 2018;4:7
    Navarro AM; Susanto E; Falk A; Wilhelm M
  • Corrigendum: CELL DEATH AND DISEASE. 2018;9(6):690
    Kostecka A; Sznarkowska A; Koczergo K; Acedo P; Shi Y; Sakil HAM; Kawiak A; Lion M; Krolicka A; Wilhelm M; Inga A; Zawacka-Pankau J
  • Corrigendum: CELL DEATH AND DISEASE. 2018;9:681
    Kostecka A; Sznarkowska A; Meller K; Acedo P; Shi Y; Sakil HM; Kawiak A; Lion M; Krolicka A; Wilhelm M; Inga A; Zawacka-Pankau J
  • Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):311
    Wolfsberger J; Sakil HM; Stantic M; Wilhelm M
  • Review: SEMINARS IN CANCER BIOLOGY. 2011;21(4):256-266
    Westermark UK; Wilhelm M; Frenzel A; Henriksson MA
  • Review: CELL DEATH AND DIFFERENTIATION. 2011;18(9):1434-1440
    Vilborg A; Bersani C; Wilhelm MT; Wiman KG
  • Review: JOURNAL OF MOLECULAR MEDICINE. 2010;88(7):645-652
    Vilborg A; Wilhelm MT; Wiman KG
  • Book chapter: ZINC FINGER PROTEINS: MOLECULAR BIOLOGY INTELLIGENCE UNIT. 2005;p. 76-79
    Mendez-Vidal C; Hellborg F; Wilhelm MT; Tarkowska M; Wiman KG
  • Book chapter: TRANSCRIPTION FACTORS: HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. 2004;p. 209-258
    Asker C; Bykov VJN; Mendez-Vidal C; Selivanova G; Wilhelm MT; Wiman KG
  • Thesis / dissertation: 2003
    Wilhelm, Margareta

Forskningsbidrag

  • Swedish Research Council
    1 January 2024 - 31 December 2026
  • Swedish Cancer Society
    1 January 2023
  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • Barncancerfonden
    1 January 2021 - 31 December 2021
  • Swedish Cancer Society
    1 January 2020
  • Identification of mechanisms regulating tumor development, and generation of next-generation cancer models using cellular reprogramming
    Swedish Cancer Society
    1 January 2019
  • Mechanisms controlled by p73 isoforms during tumor development
    Swedish Cancer Society
    1 January 2018
  • Swedish Research Council
    1 January 2017 - 31 December 2019
  • Mechanisms controlled by p73 isoforms during tumor development
    Swedish Cancer Society
    1 January 2017
  • Mechanisms controlled by p73 isoforms during tumor development
    Swedish Cancer Society
    1 January 2016
  • Study on how two different p73 protein variants control tumor development.
    Swedish Cancer Society
    1 January 2015
  • Study on how two different p73 protein variants control tumor development.
    Swedish Cancer Society
    1 January 2014
  • Knut and Alice Wallenberg Foundation
    1 January 2013 - 1 January 2018
  • Swedish Research Council
    1 January 2013 - 31 December 2015
  • Swedish Research Council
    1 January 2011 - 31 December 2014
  • Swedish Research Council
    1 January 2011 - 31 December 2013
  • Swedish Research Council
    1 January 2009 - 31 December 2012

´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù

  • Senior Forskare, Institutionen för mikrobiologi, tumör- och cellbiologi, ̽»¨¾«Ñ¡, 2022-

Examina och utbildning

  • Docent, Tumörbiologi, ̽»¨¾«Ñ¡, 2016
  • MEDICINE DOKTORSEXAMEN, Institutionen för onkologi-patologi, ̽»¨¾«Ñ¡, 2003

Uppdrag

  • Sektionsansvarig, Division Tumor Biology, Microbiology, Tumor and Cell biology (MTC), ̽»¨¾«Ñ¡, 2024-

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