̽ѡ

Margaret Sällberg Chen

Margaret Sällberg Chen

Professor
E-postadress: margaret.chen@ki.se
Telefon: +46852488125
ö: Institutionen för Labmed / ANA Futura, Alfred Nobels Allé 8, 14152 Huddinge
Postadress: H5 Laboratoriemedicin, H5 Patologi Sällberg Chen, 171 77 Stockholm
Del av:

Om mig

  • Professor i klinisk oral immunologi. Studierektor för forskarutbildning och forskargruppledare vid Institutionen för laboratoriemedicin. Lärarrepresentant vid Kommittén för utbildning på forskarnivå (KFU) på KI.

     

  • Jag är legitimerad tandläkare och har genomgått både min forskarutbildning och grundutbildning vid ̽ѡ. Efter min postdoc vid The Scripps Research Institute i La Jolla, San Diego, fortsatte jag min forskning vid Folkhälsomyndigheten (tidigare Smittskyddsinstitutet) med fokus på att utveckla nya RNA-vacciner och immunoterapi för infektionssjukdomar och cancer.

     

  • Jag är aktiv inom forskarutbildningen genom mitt uppdrag som lärarrepresentant vid KFU, och är ordförande för styrgruppen för KID. Jag är studierektor för forskarutbildningen vid Labmed, och har tidigare varit studierektor för forskarutbildningen vid både DentMed (2010–2023) och MTC (2004). Som professor i ett kliniskt ämne har jag även omfattande pedagogisk och klinisk erfarenhet från grundutbildningen. Jag handleder doktorander och postdocs, och vår forskning stöds av flera externa forskningsanslag.

     

  • Jag har publicerat vetenskapliga artiklar som har citerats i över 4000 andra studier. Jag har även aktiva uppdrag inom nationella och internationella styrelser och är associate editor för flera internationella vetenskapliga tidskrifter.

Forskningsbeskrivning

  • Group members

    Dr. Michal Sobkowiak, Research specialist, Dr Sobkowiak holds a PhD in mucosal immunology

    Dr. Pooja Tajpara, Postdoc, Dr. Tajpara holds a Master in Biotechnology and a PhD in human tissue immunology.

    Dr. Mahin Ghorbani, Postdoc, Dr Ghorbani has a PhD in metatranscriptome analysis of gut microbiome and biomarker discovery.

    Dr. Zara Ahmad Khan, Postdoc, Dr Khan holds a PhD in human microbiota and microbial proteomics.

    PhD students: Rahul Harshad Nagadia (DDS, MD, Specialist in Oral and Maxillofacial Surgery), Khaled Al-Manei (DDS, MSc Specialist in Endodontics), Agne Kvedaraite (DDS, FTV Region Stockholm). Affiliated research student Choon Boon Too (Singapore NTU).

    Co-supervisor to PhD student: Ira Sotirova (Umeå University, Region Västerbotten) 



  • Alumni

    Tanja Näslund PhD 2009, Anna Pasetto PhD 2012, Haleh Davanian PhD 2014, Michal Sobkowiak PhD 2019. Hassan Alkharaan PhD 2021. Katie Healy PhD 2022, Zeeshan Ateeb PhD 2023, Asif Halimi PhD 2024, Liyan Lu PhD 2024.

    Dr. Anila Yasmeen, Postdoc. Dr. Balasiddaiah Anangi, Postdoc. Dr Rogier Gaiser, Dr Haleh Davanian, Dr Giorgio Garbarini, Dr Sabrina Naud.

    Research awards

    Cancerfonden, Vetenskapsrådet, KI KID faculty funds, CIMED, Johnson &
  • Johnson Innovation Award, KI/SLL SOF, ALF Stockholm, Radiumhemmets Forskningsfond, NBIS/SciLifeLab Bioinformatics Long-term Support

Undervisning

  • Formal courses taught at university level:
    - Course director “General Pathology”, Dentistry Programme KI, 2023 – present
    - Course director “Exam Work in Oral Sciences”, Dentistry Programme KI, 2015 – 2023
    - Course director “Medical Microbiology, Medical Programme KI, 2002
    - Curriculum Director, Year 2, Dentistry Programme KI, 2014- present
    - Clinical instructor for Dentistry Students (Year 3-5), Dentistry Programme KI, 2008-2017

Utvalda publikationer

  • Article: CELL HOST AND MICROBE. 2024;32(2):156-161.e3
    Muller TR; Gao Y; Wu J; Ribeiro O; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Soderdahl G; Smith CIE; Lore K; Chen MS; Ljungman P; Ingelman-Sundberg HM; Ljunggren H-G; Osterborg A; Sette A; Grifoni A; Aleman S; Buggert M
  • Article: NPJ BIOFILMS AND MICROBIOMES. 2023;9(1):104
    Ray S; Narayanan A; Vesterbacka J; Blennow O; Chen P; Gao Y; Gabarrini G; Ljunggren H-G; Buggert M; Manoharan L; Chen MS; Aleman S; Sonnerborg A; Nowak P
  • Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452
    Muller TRR; Sekine T; Trubach D; Niessl J; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Olofsson A; Hernandez SPA; Gao Y; Cai C; Soderdahl G; Smith CIE; Osterborg A; Lore K; Sallberg Chen M; Ljungman P; Ljunggren H-G; Karlsson ACC; Saini SK; Aleman S; Buggert M
  • Article: IMMUNITY. 2022;55(9):1732-1746.e5
    Gao Y; Cai C; Wullimann D; Niessl J; Rivera-Ballesteros O; Chen P; Lange J; Cuapio A; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Perez-Potti A; Sekine T; Muller TR; Boulouis C; Kammann T; Parrot T; Muvva JR; Sobkowiak M; Healy K; Bogdanovic G; Muschiol S; Soderdahl G; Osterborg A; Hellgren F; Grifoni A; Weiskopf D; Sette A; Lore K; Chen MS; Ljungman P; Sandberg JK; Smith CIE; Bergman P; Ljunggren H-G; Aleman S; Buggert M
  • Article: MED. 2022;3(2):137-153.e3
    Healy K; Pin E; Chen P; Soderdahl G; Nowak P; Mielke S; Hansson L; Bergman P; Smith CIE; Ljungman P; Valentini D; Blennow O; Osterborg A; Gabarrini G; Al-Manei K; Alkharaan H; Sobkowiak MJ; Yousef J; Mravinacova S; Cuapio A; Xu X; Akber M; Lore K; Hellstrom C; Muschiol S; Bogdanovic G; Buggert M; Ljunggren H-G; Hober S; Nilsson P; Aleman S; Chen MS
  • Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1079995
    Ghorbani M; Al-Manei K; Naud S; Healy K; Gabarrini G; Sobkowiak MJ; Chen P; Ray S; Akber M; Muschiol S; Bogdanovic G; Bergman P; Ljungman P; Buggert M; Ljunggren H-G; Pin E; Nowak P; Aleman S; Saellberg Chen M
  • Article: JCI INSIGHT. 2021;6(5):140074
    Parrot T; Healy K; Boulouis C; Sobkowiak MJ; Leeansyah E; Aleman S; Bertoletti A; Chen MS; Sandberg JK
  • Article: GUT MICROBES. 2021;13(1):1983101
    Halimi A; Gabarrini G; Sobkowiak MJ; Ateeb Z; Davanian H; Gaiser RA; Arnelo U; Valente R; Wong AYW; Moro CF; Del Chiaro M; Ozenci V; Chen MS
  • Article: GUT. 2019;68(12):2186-2194
    Gaiser RA; Halimi A; Alkharaan H; Lu L; Davanian H; Healy K; Hugerth LW; Ateeb Z; Valente R; Moro CF; Del Chiaro M; Chen MS
  • Article: JOURNAL OF HEPATOLOGY. 2019;71(4):673-684
    Soon CF; Behrendt P; Todt D; Manns MP; Wedemeyer H; Chen MS; Cornberg M
  • Article: INTERNATIONAL JOURNAL OF ORAL SCIENCE. 2019;11(2):16
    Davanian H; Gaiser RA; Silfverberg M; Hugerthz LW; Sobkowiak MJ; Lu L; Healy K; Sandberg JK; Nasman P; Karlsson J; Jansson L; EngstrancP L; Chen MS
  • Article: GASTROENTEROLOGY. 2018;155(1):180-193.e6
    Koh S; Kah J; Tham CYL; Yang N; Ceccarello E; Chia A; Chen M; Khakpoor A; Pavesi A; Tan AT; Dandri M; Bertoletti A

Artiklar

  • Journal article: JOURNAL OF DENTAL SCIENCES. 2024;19:S17-S25
    Lu L; Yan L; Sohrabi A; Lindahl K; Cederberg S; Wang R; Ye W; Aleman S; Chen MS
  • Article: EBIOMEDICINE. 2024;109:105385
    Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Gao Y; Soderdahl G; Osterborg A; Smith CIE; Vesterbacka J; Wullimann D; Cuapio A; Akber M; Bogdanovic G; Muschiol S; Aberg M; Lore K; Chen MS; Ljungman P; Buggert M; Aleman S; Ljunggren H-G
  • Article: SCIENTIFIC REPORTS. 2024;14(1):17820
    Narayanan A; Kieri O; Vesterbacka J; Manoharan L; Chen P; Ghorbani M; Ljunggren H-G; Chen MS; Aleman S; Soennerborg A; Ray S; Nowak P
  • Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1346749
    Bladh O; Aguilera K; Marking U; Kihlgren M; Norin NG; Smed-Sorensen A; Chen MS; Klingstrom J; Blom K; Russell MW; Havervall S; Thalin C; Aberg M
  • Article: ORAL ONCOLOGY. 2023;146:106556
    Al-Manei K; Sobkowiak MJ; Nagadia RH; Heymann R; Chen MS; Ozenci V
  • Article: EBIOMEDICINE. 2023;94:104700
    Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; oesterborg A; Smith CIE; Vesterbacka J; Wullimann D; Cuapio A; Akber M; Bogdanovic G; Muschiol S; aberg M; Lore K; Chen MS; Buggert M; Ljungman P; Aleman S; Ljunggren H-G
  • Article: JOURNAL OF HEMATOLOGY. 2023;12(4):170-175
    Andersson M; Wu J; Wullimann D; Gao Y; Aberg M; Muschiol S; Healy K; Naud S; Bogdanovic G; Palma M; Mellstedt H; Chen P; Ljunggren H-G; Hansson L; Chen MS; Buggert M; Ingelman-Sundberg HM; Osterborg A
  • Article: MICROBIOLOGY SPECTRUM. 2022;10(6):e0248722-e02422
    Al-Manei K; Ghorbani M; Naud S; Al-Manei KK; Sobkowiak MJ; Lund B; Hazirolan G; Chen MS; Ozenci V
  • Article: BRITISH JOURNAL OF CANCER. 2022;127(12):2133-2140
    Yu J; Ploner A; Chen MS; Zhang J; Sandborgh-Englund G; Ye W
  • Article: JOURNAL OF INFECTIOUS DISEASES. 2022;226(8):1428-1440
    Gibbs A; Healy K; Kaldhusdal V; Sundling C; Franzen-Boger M; Edfeldt G; Buggert M; Lajoie J; Fowke KR; Kimani J; Kwon DS; Andersson S; Sandberg JK; Broliden K; Davanian H; Chen MS; Tjernlund A
  • Article: JOURNAL OF VIRAL HEPATITIS. 2022;29(9):835-839
    Healy K; Freij U; Ellerstad M; Aulin LBS; Bruckle L; Hillmering H; Chen MS; Gustafsson R
  • Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2022;31(7):1418-1425
    Zhang J; Bellocco R; Sandborgh-Englund G; Yu J; Chen MS; Ye W
  • Article: MOLECULAR MEDICINE. 2022;28(1):54
    Boulouis C; Kammann T; Cuapio A; Parrot T; Gao Y; Mouchtaridi E; Wullimann D; Lange J; Chen P; Akber M; Ballesteros OR; Muvva JR; Smith CIE; Vesterbacka J; Kieri O; Nowak P; Bergman P; Buggert M; Ljunggren H-G; Aleman S; Sandberg JK
  • Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):462-471
    Sobkowiak MJ; Paquin-Proulx D; Bosnjak L; Moll M; Chen MS; Sandberg JK
  • Article: MOLECULAR MEDICINE. 2022;28(1):20
    Cuapio A; Boulouis C; Filipovic I; Wullimann D; Kammann T; Parrot T; Chen P; Akber M; Gao Y; Hammer Q; Strunz B; Potti AP; Ballesteros OR; Lange J; Muvva JR; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; Osterborg A; Smith CIE; Bogdanovic G; Muschiol S; Hellgren F; Lore K; Sobkowiak MJ; Gabarrini G; Healy K; Chen MS; Alici E; Bjorkstrom NK; Buggert M; Ljungman P; Sandberg JK; Aleman S; Ljunggren H-G
  • Article: LEUKEMIA. 2022;36(2):476-481
    Blixt L; Bogdanovic G; Buggert M; Gao Y; Hober S; Healy K; Johansson H; Kjellander C; Mravinacova S; Muschiol S; Nilsson P; Palma M; Pin E; Smith CIE; Stromberg O; Chen MS; Zain R; Hansson L; Osterborg A
  • Article: FRONTIERS IN IMMUNOLOGY. 2022;13:896242
    Silva DN; Chrobok M; Rovesti G; Healy K; Wagner AK; Maravelia P; Gatto F; Mazza M; Mazzotti L; Lohmann V; Chen MS; Sallberg M; Buggert M; Pasetto A
  • Article: EBIOMEDICINE. 2021;74:103705
    Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Chen P; Soderdahl G; Osterborg A; Smith CIE; Wullimann D; Vesterbacka J; Lindgren G; Blixt L; Friman G; Wahren-Borgstrom E; Nordlander A; Gomez AC; Akber M; Valentini D; Norlin A-C; Thalme A; Bogdanovic G; Muschiol S; Nilsson P; Hober S; Lore K; Chen MS; Buggert M; Ljunggren H-G; Ljungman P; Aleman S
  • Article: JOURNAL OF INFECTIOUS DISEASES. 2021;224(3):407-414
    Alkharaan H; Bayati S; Hellstrom C; Aleman S; Olsson A; Lindahl K; Bogdanovic G; Healy K; Tsilingaridis G; De Palma P; Hober S; Manberg A; Nilsson P; Pin E; Chen MS
  • Article: JHEP REPORTS. 2021;3(4):100318
    Healy K; Pavesi A; Parrot T; Sobkowiak MJ; Reinsbach SE; Davanian H; Tan AT; Aleman S; Sandberg JK; Bertoletti A; Chen MS
  • Visa fler

Alla övriga publikationer

  • Preprint: RESEARCH SQUARE. 2024
    Narayanan A; Kieri O; Vesterbacka J; Manoharan L; Chen P; Ghorbani M; Ljunggren H-G; Chen MS; Aleman S; Sönnerborg A; Ray S; Nowak P
  • Letter: HAEMATOLOGICA. 2024;109(2):646-651
    Ingelman-Sundberg HM; Blixt L; Wullimann D; Wu J; Gao Y; Healy K; Muschiol S; Bogdanovic G; Aberg M; Kjellander C; Grifoni A; Sette A; Aleman S; Chen P; Blennow O; Hansson L; Ljunggren H-G; Chen MS; Buggert M; Osterborg A
  • Letter: BLOOD. 2022;140(22):2403-2407
    Blixt L; Gao Y; Wullimann D; Ingelman-Sundberg HM; Muschiol S; Healy K; Bogdanovic G; Pin E; Nilsson P; Kjellander C; Grifoni A; Sette A; Chen MS; Ljunggren H-G; Buggert M; Hansson L; Osterborg A
  • Corrigendum: SCIENTIFIC REPORTS. 2022;12(1):5281
    Gaiser RA; Pessia A; Ateeb Z; Davanian H; Moro CF; Alkharaan H; Healy K; Ghazi S; Arnelo U; Valente R; Velagapudi V; Chen MS; Del Chiaro M
  • Preprint: MEDRXIV. 2020;MEDRXIV
    Morgell A; Reisz JA; Ateeb Z; Davanian H; Reinsbach SE; Halimi A; Gaiser R; Valente R; Arnelo U; Chiaro MD; Sällberg Chen M; D'Alessandro A
  • Review: CELLS. 2020;9(6):E1471-1471
    Healy K; Pasetto A; Sobkowiak MJ; Soon CF; Cornberg M; Aleman S; Chen MS
  • Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S83-S84
    Healy K; Pavesi A; Parrot T; Davanian H; Tan A; Sandberg JK; Bertoletti A; Chen MS
  • Meeting abstract: JOURNAL OF HEPATOLOGY. 2018;68:s798-s799
    Soon C; Chen MS; Manns MP; Wedemeyer H; Cornberg M
  • Conference publication: JOURNAL OF VIRAL HEPATITIS. 2018;25:123
    Soon C; Chen MS; Manns M; Wedemeyer H; Cornberg M
  • Review: EXPERT REVIEW OF VACCINES. 2016;15(5):629-640
    Chen M; Jagya N; Bansal R; Frelin L; Sallberg M
  • Review: MEDICAL MICROBIOLOGY AND IMMUNOLOGY. 2015;204(1):131-135
    Sallberg M; Frelin L; Ahlen G; Sallberg-Chen M
  • Review: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS. 2014;62(1):23-30
    Pasetto A; Aleman S; Chen M
  • Review: DRUG RESISTANCE UPDATES. 2013;16(3-5):60-67
    Ahlen G; Frelin L; Brenndorfer ED; Brass A; Weiland O; Chen M; Sallberg M
  • Meeting abstract: JOURNAL OF HEPATOLOGY. 2011;54:S476-S477
    Frelin L; Ahlen G; Chen A; Brenndorfer ED; Brass A; Holmstrom F; Chen M; Soderholm J; Milich DR; Sallberg M
  • Published conference paper: ANTIVIRAL RESEARCH. 2001;52(2):99-111
    Chen M; Sällberg M; Thung SN; Hughes J; Jones J; Milich DR
  • Thesis / dissertation: 1998
    Chen, Margaret
  • Other: JOURNAL OF INFECTIOUS DISEASES. 1995;171(5):1356-1359
    ZHANG ZX; CHEN M; SONNERBORG A; WEILAND O; SALLBERG M
  • Other: JOURNAL OF CLINICAL MICROBIOLOGY. 1995;33(3):778-780
    CHEN M; SONNERBORG A; SALLBERG M
  • Addendum: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 1995;27(5):319-324
    Weiland O; Chen M; Lindh G; Mattsson L; Schvarcz R; Sönnerborg A; Wahl M; Wejstål R; Widell A; Norkrans G

Forskningsbidrag

  • Radiumhemmets Forskningsfonder
    1 January 2024 - 31 December 2025
  • Cancerfonden
    1 January 2023 - 31 December 2025
  • Swedish Cancer Society
    1 January 2023
  • CIMED
    1 January 2022 - 31 December 2024
  • Swedish Research Council
    1 June 2021 - 31 May 2025
  • Swedish Research Council
    1 January 2021 - 31 December 2023
  • RNA as cell therapy and tumor marker to prevent cancer
    Swedish Cancer Society
    1 January 2018
  • RNA as cell therapy and tumor marker to prevent cancer
    Swedish Cancer Society
    1 January 2017
  • RNA as cell therapy and tumor marker to prevent cancer
    Swedish Cancer Society
    1 January 2016
  • T cell Receptor Transfer: Translationella Studier för Förbättrad Behandling av Virushepatit and Levercancer
    Swedish Cancer Society
    1 January 2015
  • T cell Receptor Transfer: Translationella Studier för Förbättrad Behandling av Virushepatit and Levercancer
    Swedish Cancer Society
    1 January 2014
  • Swedish Research Council
    1 January 2009 - 31 December 2010

ԲäԾԲ

  • Professor, Laboratoriemedicin, ̽ѡ, 2023-
  • Professor, Odontologi, ̽ѡ, 2023-2026

Examina och utbildning

  • DOKTORSEXAMEN I MEDICINSK VETENSKAP, Institutionen för odontologi, ̽ѡ, 1998
  • Doctor Of Medical Science, Department of Laboratory Medicine, Karolinska Institute, 1998

Uppdrag i kommitté

  • Medlem, Committee for Doctoral Education of Karolinska Instititet
  • Ordförande, Steering group for KID-funding

Nyheter från KI

Kalenderhändelser från KI