Marcus Buggert
Forskarassistent | Docent
E-postadress: marcus.buggert@ki.se
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postadress: H7 Medicin, Huddinge, H7 CIM Buggert, 171 77 Stockholm
Om mig
- Docent och gruppledare vid Institutionen för medicin. Min forskning
fokuserar på cellmedierad immunitet mot virusinfektioner och cancer.
Master i biomedicin vid KI, 2004-2009. Doktorandstudier vid KI, 2010-2014.
Post doc vid University of Pennsylvania, USA, 2014-2017. Docent vid KI,
2018-. Gruppledare på KI, 2019-. Docent vid KI, 2021-
Forskningsbeskrivning
- Forskningen i min grupp T-cellsimmunitet mot virusinfektioner och cancer, [1]
bedrivs vid Centrum för infektionsmedicin (CIM) i Huddinge.
​ [2]Vår grupp forskar på cellmedierad immunitet. Mer specifikt är vi
intresserade av att förstå hur minnes T-celler känner igen och eliminerar
virusinfektioner och tumörer. T-celler är kritiska för immunkontroll av de
flesta virusinfektioner och utgör också en central komponent för
immunterapier som helt har revolutionerat behandlingsalternativen inom
³¦²¹²Ô³¦±ð°ù±¹Ã¥°ù»å±ð²Ô.
Mycket av vår nuvarande förståelse av minnes T-cellfunktioner härrör
dock från studier av perifert blod hos människor. Med ny data från oss och
andra som visar att de flesta minnes T-celler i vävnader är
icke-cirkulerande residenta celler, är det nödvändigt att bättre förstå
hur, var och vilken typ av T-celler som genererar immunitet i kroppen. Min
grupp fokuserar vårt arbete kring dessa frågeställningar med det
övergripande syftet att i) studera diversitet av minnes T-celler i
mänskliga organdonatorer, ii) identifiera alternativa funktioner för minnes
T-celler i mänskliga vävnader, och iii) förstå hur minnes T-celler
upprätthåller kontrollen över tumörer och virusinfektioner, såsom HIV
och SARS-CoV-2.
[1] /medh/marcus-buggerts-grupp-t-cellsimmunitet-mot-virusinfektioner-och-cancer
[2] /en/medh/marcus-buggert-group-human-memory-cd8-t-cells
Artiklar
- Journal article: IMMUNITY. 2024;57(9):2007-2009
- Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;44(5):116
- Article: GENES AND IMMUNITY. 2024;25(2):168-169
- Article: NATURE COMMUNICATIONS. 2024;15(1):1752
- Article: CELL HOST AND MICROBE. 2024;32(2):156-161.e3
- Article: JOURNAL OF IMMUNOLOGY. 2024;212(3):389-396
- Article: NPJ BIOFILMS AND MICROBIOMES. 2023;9(1):104
- Article: SCIENCE IMMUNOLOGY. 2023;8(90):eadh0687
- Article: NATURE COMMUNICATIONS. 2023;14(1):6527
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(6):1075-1082
- Article: EBIOMEDICINE. 2023;94:104700
- Article: JOURNAL OF HEMATOLOGY. 2023;12(4):170-175
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452
- Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(7):189
- Article: CELL HOST AND MICROBE. 2023;31(6):928-936.e4
- Article: NATURE COMMUNICATIONS. 2023;14(1):2952
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):223.13
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1):63.22
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):226.09
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):75.20
- Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):75.16
- Journal article: CYTOTHERAPY. 2023;25(6):s237-s238
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(12):e2220320120
- Article: NATURE COMMUNICATIONS. 2023;14(1):1438
- Article: RESPIRATORY RESEARCH. 2023;24(1):62
- Journal article: JOURNAL OF VIRUS ERADICATION. 2022;8:100274
- Article: NATURE COMMUNICATIONS. 2022;13(1):6436
- Article: JOURNAL OF INFECTIOUS DISEASES. 2022;226(8):1428-1440
- Article: CELLS. 2022;11(19):3142
- Article: IMMUNITY. 2022;55(9):1732-1746.e5
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(6):1130-1136
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
- Article: MOLECULAR MEDICINE. 2022;28(1):54
- Journal article: JOURNAL OF IMMUNOLOGY. 2022;208(1):169.16
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(4):716-727
- Article: NATURE MEDICINE. 2022;28(3):472-476
- Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510
- Article: MED. 2022;3(2):137-153.e3
- Article: MOLECULAR MEDICINE. 2022;28(1):20
- Article: LEUKEMIA. 2022;36(2):476-481
- Journal article: NATURE MEDICINE. 2022
- Article: METHODS IN MOLECULAR BIOLOGY. 2022;2574:209-219
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:834862
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:896242
- Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1079995
- Article: EBIOMEDICINE. 2021;74:103705
- Article: SCIENCE IMMUNOLOGY. 2021;6(64):eabk0894
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(599):eabb3107
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(11):e2016580118
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:744530
- Article: PLOS ONE. 2021;16(9):e0258041
- Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
- Article: CELL. 2020;183(7):1946-1961.e15
- Article: SCIENCE IMMUNOLOGY. 2020;5(53):eabe8063
- Article: CELL. 2020;183(1):158-168.e14
- Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
- Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
- Journal article: JOURNAL OF HEPATOLOGY. 2020;73:s630-s631
- Journal article: JOURNAL OF HEPATOLOGY. 2020;73:s576
- Article: SCIENCE IMMUNOLOGY. 2020;5(49):eaba7918
- Article: JOURNAL OF VIROLOGY. 2020;94(14):e02128-e02119
- Journal article: JOURNAL OF IMMUNOLOGY. 2020;204(1_Supplement):86.46
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2019;11(523):eaax4077
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2019;129(8):3185-3200
- Article: JOURNAL OF INFECTIOUS DISEASES. 2019;219(11):1749-1754
- Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):51.5
- Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):189.7
- Journal article: JOURNAL OF IMMUNOLOGY. 2019;202(1_Supplement):121.16
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(49):E11513-E11522
- Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(137)
- Journal article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(137)
- Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):453-465
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2018;215(6):1531-1542
- Article: SCIENCE IMMUNOLOGY. 2018;3(24):eaar4526
- Journal article: JOURNAL OF IMMUNOLOGY. 2018;200(1_Supplement):120.12
- Article: JCI INSIGHT. 2018;3(7):98487
- Article: PLOS PATHOGENS. 2018;14(4):e1006973
- Article: FRONTIERS IN IMMUNOLOGY. 2018;9:19
- Article: CELL REPORTS. 2017;21(12):3458-3470
- Journal article: JOURNAL OF VIRUS ERADICATION. 2017;3:32
- Journal article: JOURNAL OF IMMUNOLOGY. 2017;198(1_Supplement):78.25
- Journal article: JOURNAL OF IMMUNOLOGY. 2017;198(1_Supplement):152.7
- Article: JCI INSIGHT. 2017;2(8):92943
- Article: TRANSLATIONAL CANCER RESEARCH. 2017;6:S65-S67
- Article: SCIENTIFIC REPORTS. 2017;7:40354
- Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2017;214(1):91-106
- Article: AIDS. 2016;30(16):2415-2426
- Article: PLOS PATHOGENS. 2016;12(8):e1005805
- Article: AIDS. 2016;30(11):1713-1722
- Article: CLINICAL IMMUNOLOGY. 2015;161(2):180-189
- Article: PLOS PATHOGENS. 2015;11(8):e1005072
- Article: FRONTIERS IN IMMUNOLOGY. 2015;6:196
- Article: PLOS ONE. 2015;10(9):e0137635
- Article: CYTOMETRY. PART A : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR ANALYTICAL CYTOLOGY. 2014;85A(11):969-977
- Article: PLOS PATHOGENS. 2014;10(7):e1004251
- Article: JOURNAL OF IMMUNOLOGY. 2014;192(10):4685-4696
- Article: JOURNAL OF IMMUNOLOGY. 2014;192(5):2099-2108
- Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(3):602-612
- Article: JOURNAL OF VIROLOGY. 2012;86(18):9802-9816
- Article: PLOS ONE. 2012;7(7):e39874
- Article: JOURNAL OF IMMUNOLOGY. 2010;184(9):5383-5391
- Journal article:Reinvigoration of Progenitor-Exhausted CD8 T Cells by anti-CTLA-4 Contributes to the Sustained Activity of Combination Checkpoint Blockade
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Alla övriga publikationer
- Letter: HAEMATOLOGICA. 2024;109(2):646-651
- Preprint: BIORXIV. 2024
- Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;98(6):e13340
- Corrigendum: NATURE IMMUNOLOGY. 2023;24(10):1778
- Review: NATURE IMMUNOLOGY. 2023;24(10):1616-1627
- Corrigendum: NATURE IMMUNOLOGY. 2023;24(9):1591
- Editorial comment: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2023;220(7):e20230550
- Review: NATURE IMMUNOLOGY. 2023;24(7):1076-1086
- Meeting abstract: JOURNAL OF IMMUNOLOGY. 2023;210(1):59.47
- Preprint: BIORXIV. 2023
- Preprint: RESEARCH SQUARE. 2023
- Preprint: RESEARCH SQUARE. 2023
- Preprint: RESEARCH SQUARE. 2023
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:241-242
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Editorial comment: FRONTIERS IN IMMUNOLOGY. 2023;14:1159452
- Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
- Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S169
- Conference publication: CYTOTHERAPY. 2023;25(6):S237-S238
- Letter: BLOOD. 2022;140(22):2403-2407
- Preprint: RESEARCH SQUARE. 2022
- Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2022;22(9):533
- Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(4):e13153
- Letter: HAEMATOLOGICA. 2022;107(4):1000-1003
- Review: MUCOSAL IMMUNOLOGY. 2022;15(3):389-397
- Preprint: BIORXIV. 2022
- Preprint: RESEARCH SQUARE. 2022
- Preprint: MEDRXIV. 2021
- Preprint: MEDRXIV. 2021
- Review: SEMINARS IN IMMUNOLOGY. 2021;55:101505
- Conference publication: JOURNAL OF IMMUNOLOGY. 2021;206:26.12
- Conference publication: CYTOTHERAPY. 2021;23(5):S90
- Preprint: BIORXIV. 2021
- Preprint: MEDRXIV. 2021
- Preprint: BIORXIV. 2021
- Preprint: SSRN ELECTRONIC JOURNAL. 2021
- Editorial comment: NATURE IMMUNOLOGY. 2021;22(1):8-9
- Preprint: SSRN. 2021
- Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:95
- Conference publication: ANNALS OF ONCOLOGY. 2020;31:S1426
- Preprint: MEDRXIV. 2020
- Preprint: BIORXIV. 2020
- Editorial comment: SCIENCE IMMUNOLOGY. 2020;5(50):eabd3638
- Preprint: MEDRXIV. 2020
- Preprint: BIORXIV. 2020
- Conference publication: ZEITSCHRIFT FUR GASTROENTEROLOGIE. 2020;58(01):e38
- Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S630-S631
- Conference publication: JOURNAL OF IMMUNOLOGY. 2020;204(1)
- Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S576
- Preprint: BIORXIV. 2019
- Review: CURRENT OPINION IN HIV AND AIDS. 2019;14(2):93-99
- Conference publication: JOURNAL OF IMMUNOLOGY. 2019;202(1)
- Conference publication: JOURNAL OF IMMUNOLOGY. 2018;200(1)
- Review: FRONTIERS IN IMMUNOLOGY. 2018;9:1602
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):318
- Conference publication: JOURNAL OF IMMUNOLOGY. 2017;198(1)
- Conference publication: JOURNAL OF IMMUNOLOGY. 2017;198(1)
- Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2017;37(2):230
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):288-289
- Conference publication: JOURNAL OF IMMUNOLOGY. 2016;196:146.4
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2016;32:307
- Review: CELLULAR IMMUNOLOGY. 2015;298(1-2):126-133
- Thesis / dissertation: 2014
- Conference publication: IMMUNOLOGY. 2014;143:108
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2013;77(4):325
- Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2011;27(10):A88
- Conference publication: 2010;:658-659
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Forskningsbidrag
- Swedish Research Council1 December 2023 - 30 November 2026
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 January 2023 - 31 December 2025
- Swedish Research Council1 December 2022 - 31 December 2026
- Swedish Research Council1 December 2022 - 30 November 2025
- Deutsche Forschungsgemeinschaft1 January 2022 - 31 December 2024
- Swedish Research Council1 December 2021 - 30 November 2024
- Swedish Research Council1 December 2021 - 30 November 2025
- Swedish Research Council1 June 2021 - 31 May 2025
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Swedish Research Council1 August 2020 - 31 December 2020
- Swedish Research Council1 January 2019 - 31 December 2022
- Define the origin and subset of PD-1+ CD8+ T cells responding to cancer immunotherapySwedish Cancer Society1 January 2019
- Swedish Research Council1 January 2015 - 31 December 2017
´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù
- Forskarassistent, Medicin, Huddinge, ̽»¨¾«Ñ¡, 2018-2026
Examina och utbildning
- Docent, Immunologi, ̽»¨¾«Ñ¡, 2021
- Medicine Doktorsexamen, Institutionen för laboratoriemedicin, ̽»¨¾«Ñ¡, 2014
Nyheter från KI
Kalenderhändelser från KI
Nyheter från externa medier
- KNUT AND ALICE WALLENBERG FOUNDATION. 2023
- KNUT OCH ALICE WALLENBERGS STIFTELSE. 2023