̽»¨¾«Ñ¡

Luana Naia

Luana Naia

Biträdande Lektor
E-postadress: luana.naia@ki.se
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: BlickagÃ¥ngen 6, 14157 Huddinge
Postadress: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Neurogeriatrik Ankarcrona, 171 77 Stockholm
Del av:

Om mig

  • My scientific career has been grounded on studying mitochondrial function, dynamics and mitotherapeutics with potential to reach clinical studies. I 


  • received my PhD in neuroscience and health sciences in 2017 from Faculty of Medicine, University of Coimbra, Portugal. My post-doctoral work was focused on the study of mitochondria-endoplasmic reticulum contact sites (MERCS) in neurodegeneration and drug discovery to modulate MERCS. In 2023, I was appointed as Assistant Professor at ̽»¨¾«Ñ¡ where I develop my research line which is focused on neuron-astrocyte mitochondrial communication with a focus on Alzheimer´s Disease.

Forskningsbeskrivning

  • ´ Mitochondria are the clandestine rulers of our world`
    My research is focused on mitochondrial function, dynamics, and organelle interplay (mitochondria associated membranes) in neurodegeneration. My current projects intend to explore the mechanisms underlying mitochondrial dynamics dysfunction and their contribution for bioenergetic dysregulation in Alzheimer´s disease. We are particularly interested in studying mitochondria fission, and transfer between neurons and glia cells, with a special focus on the transfer mediated by mitochondrial-derived extracellular vesicles – mitovesicles. We further aim to explore the potential of mitovesicles as a therapeutical strategy and/or biomarker for disease progression.

Undervisning

  • 2022-present: Coordinating and lecturing the PhD course Alzheimer’s disease: clinical features and pathogenic mechanisms (̽»¨¾«Ñ¡)
    2019-present: Teaching Cell death mechanisms in the PhD course Protein Mechanisms in Health and Disease, from the Clinical Research School in Molecular Medicine (̽»¨¾«Ñ¡)
    2018-present: Teaching Mechanisms of Neurodegeneration in the Master programme in Biomedicine (̽»¨¾«Ñ¡)

Artiklar

  • Journal article: CELLS. 2023;12(19):2397
    Almeida F; Ferreira IL; Naia L; Marinho D; Vilaca-Ferreira AC; Costa MD; Duarte-Silva S; Maciel P; Rego AC
  • Article: MOLECULAR PSYCHIATRY. 2023;28(9):3966-3981
    Naia L; Shimozawa M; Bereczki E; Li X; Liu J; Jiang R; Giraud R; Leal NS; Pinho CM; Berger E; Falk VL; Dentoni G; Ankarcrona M; Nilsson P
  • Article: JOURNAL OF NEUROINFLAMMATION. 2023;20(1):43
    Zysk M; Beretta C; Naia L; Dakhel A; Pavenius L; Brismar H; Lindskog M; Ankarcrona M; Erlandsson A
  • Article: JOURNAL OF ALZHEIMER'S DISEASE. 2022;90(2):565-583
    Dentoni G; Naia L; Portal B; Leal NS; Nilsson P; Lindskog M; Ankarcrona M
  • Article: CELLS. 2022;11(3):514
    Dentoni G; Naia L; Ankarcrona M
  • Article: SCIENTIFIC REPORTS. 2021;11(1):21975
    Geva M; Gershoni-Emek N; Naia L; Ly P; Mota S; Rego AC; Hayden MR; Levin LA
  • Article: NEUROTHERAPEUTICS. 2021;18(2):1017-1038
    Naia L; Ly P; Mota SI; Lopes C; Maranga C; Coelho P; Gershoni-Emek N; Ankarcrona M; Geva M; Hayden MR; Rego AC
  • Article: BMC BIOLOGY. 2021;19(1):57
    Naia L; Pinho CM; Dentoni G; Liu J; Leal NS; Ferreira DMS; Schreiner B; Filadi R; Fao L; Connolly NMC; Forsell P; Nordvall G; Shimozawa M; Greotti E; Basso E; Theurey P; Gioran A; Joselin A; Arsenian-Henriksson M; Nilsson P; Rego AC; Ruas JL; Park D; Bano D; Pizzo P; Prehn JHM; Ankarcrona M
  • Article: FREE RADICAL BIOLOGY AND MEDICINE. 2021;163:163-179
    Naia L; Carmo C; Campesan S; Fao L; Cotton VE; Valero J; Lopes C; Rosenstock TR; Giorgini F; Rego AC
  • Article: CELLS. 2020;9(12):E2552-2552
    Leal NS; Dentoni G; Schreiner B; Naia L; Piras A; Graff C; Cattaneo A; Meli G; Hamasaki M; Nilsson P; Ankarcrona M
  • Article: METHODS IN MOLECULAR BIOLOGY. 2018;1780:415-442
    Ferreira IL; Carmo C; Naia L; I Mota S; Cristina Rego A
  • Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2018;1049:59-83
    Carmo C; Naia L; Lopes C; Cristina Rego A
  • Article: HUMAN MOLECULAR GENETICS. 2017;26(21):4105-4117
    Lemos V; de Oliveira RM; Naia L; Szego E; Ramos E; Pinho S; Magro F; Cavadas C; Rego AC; Costa V; Outeiro TF; Gomes P
  • Article: MOLECULAR NEUROBIOLOGY. 2017;54(7):5385-5399
    Naia L; Rosenstock TR; Oliveira AM; Oliveira-Sousa SI; Caldeira GL; Carmo C; Laco MN; Hayden MR; Oliveira CR; Cristina Rego A
  • Article: JOURNAL OF NEUROSCIENCE. 2017;37(10):2776-2794
    Naia L; Cunha-Oliveira T; Rodrigues J; Rosenstock TR; Oliveira A; Ribeiro M; Carmo C; Oliveira-Sousa SI; Duarte AI; Hayden MR; Cristina Rego A
  • Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;483(4):1069-1077
    Naia L; Ferreira IL; Ferreiro E; Cristina Rego A
  • Article: NEUROPEPTIDES. 2016;58:73-81
    Naia L; Ribeiro M; Rodrigues J; Duarte AI; Lopes C; Rosenstock TR; Hayden MR; Cristina Rego A
  • Article: MOLECULAR NEUROBIOLOGY. 2015;51(1):331-348
    Naia L; Luisa Ferreira I; Cunha-Oliveira T; Duarte AI; Ribeiro M; Rosenstock TR; Laco MN; Ribeiro MJ; Oliveira CR; Saudou F; Humbert S; Cristina Rego A
  • Article: PLOS ONE. 2015;10(10):e0141610
    Esteves S; Duarte-Silva S; Naia L; Neves-Carvalho A; Teixeira-Castro A; Rego AC; Silva-Fernandes A; Maciel P
  • Article: NEURODEGENERATIVE DISEASES. 2015;15(4):207-218
    Silva A; Naia L; Dominguez A; Ribeiro M; Rodrigues J; Vieira OV; Lessmann V; Rego AC
  • Visa fler

Alla övriga publikationer

  • Preprint: BIORXIV. 2023
    Casas PG; Rossini M; Påvénius L; Saeed M; Arnst N; Sonda S; Bruzzone M; Berno V; Raimondi A; Sassano ML; Naia L; Agostinis P; Sturlese M; Niemeyer B; Brismar H; Ankarcrona M; Gautier A; Pizzo P; Filadi R
  • Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:920228
    Dentoni G; Castro-Aldrete L; Naia L; Ankarcrona M
  • Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2018;120:S17
    Naia L; Carmo C; Campesan S; Lopes C; Valero J; Rosenstock TR; Giorgini F; Cristina Rego A
  • Conference publication: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2018;48:55
    Naia L; Maranga C; Lopes C; Geva M; Hayden M; Cristina Rego A
  • Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1852(10):2183-2194
    Naia L; Rego AC

Forskningsbidrag

  • Start-up grant
    StratNeuro
    15 April 2024 - 15 April 2026
  • Mitovesiklar: en ny strategi för att förstÃ¥ och lindra neurodegeneration av Alzheimers sjukdom
    ³Õ±ð³Ù±ð²Ô²õ°ì²¹±è²õ°ùÃ¥»å±ð³Ù
    1 January 2024 - 31 December 2027
  • Nya innovativa vägar mot Alzheimers sjukdom: Vätskebiomarkörer och intracellulära behandlingar
    Private donation from Leif Lundblad Family and others
    1 October 2023 - 30 September 2026
  • Potential för extracellulära mitokondrier för terapi och diagnos vid Alzheimers
    Petrus och Augusta Hedlunds Stiftelse
    2 January 2022 - 31 January 2024
  • Mitochondria on the road: neuroglial crosstalk in Alzheimer’s disease
    StartNeuro – funding for postdoctoral researchers
    1 June 2020 - 31 December 2021
  • Exploring extracellular mitochondria in Alzheimer's disease: from organelle-based therapy to biomarkers
    Alzheimerfonden
    1 January 2020 - 31 December 2023

´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù

  • Biträdande Lektor, Neurobiologi, vÃ¥rdvetenskap och samhälle, ̽»¨¾«Ñ¡, 2022-2028
  • Postdoctoral Researcher, Mitochondria and neurodegeneration, Center for Neuroscience and Cell Biology (CNC), 2017-2018

Examina och utbildning

  • PhD in Neurosciences, Health Sciences – field Neuroscience, Role of lysine deacetylases on transcription regulation and mitochondrial function in Huntington's disease, Faculty of Medicine, University of Coimbra, 2017
  • Master in Biotechnology, Biotechnology in Health Sciences, University of Trás-os-Montes and Alto Douro, 2011
  • Bachelor in Genetics and Biotechnology, University of Trás-os-Montes and Alto Douro, 2008

Nyheter från KI

Kalenderhändelser från KI