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Lars Holmgren

Lars Holmgren

Professor | Prefekt | Docent
E-postadress: lars.holmgren@ki.se
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: J6:20 BioClinicum, Akademiska strÃ¥ket 1, 17164 Solna
Postadress: K7 Onkologi-Patologi, K7 Övriga Holmgren, 171 77 Stockholm

Om mig

  • Professor i tumörbiologi vid ̽»¨¾«Ñ¡ 2008-
    Ordförande tema cancer, U2/Bioclinicum planering 2012-
    Ordförande hörandeförsamling, 2013
    Ordförande nomineringsförsamling, 2011-2013
    Koordinator EU-consortium EUCAAD, 2008-2012
    Medlem av advisory board Paoli Calmette Cancer Center, Marseille
    Utvärderare av forskning, Vetenskapsrådet, Cancerfonden, Fernströms stiftelse, Internationella anslag
    Studierektor doktorandutbildning, OnkPat, 2004-2014

Forskningsbeskrivning

  • Min forskning ligger inom ämnet tumörbiologi med inriktning pÃ¥ hur individuella celler bildar funktionella organ och hur dessa processer reverteras under canceromvandling. VÃ¥ra projekt innefattar cell och molekylärbiologiska studier av pre-klinisk karaktär samt studier av patient material.

Utvalda publikationer

  • Article: NATURE COMMUNICATIONS. 2014;5:4557
    Mojallal M; Zheng Y; Hultin S; Audebert S; van Harn T; Johnsson P; Lenander C; Fritz N; Mieth C; Corcoran M; Lembo F; Hallstroem M; Hartman J; Mazure NM; Weide T; Grander D; Borg J-P; Uhlen P; Holmgren L
  • Article: NATURE COMMUNICATIONS. 2014;5:3743
    Hultin S; Zheng Y; Mojallal M; Vertuani S; Gentili C; Balland M; Milloud R; Belting H-G; Affolter M; Helker CSM; Adams RH; Herzog W; Uhlen P; Majumdar A; Holmgren L
  • Article: SCIENCE SIGNALING. 2013;6(291):ra77
    Yi C; Shen Z; Stemmer-Rachamimov A; Dawany N; Troutman S; Showe LC; Liu Q; Shimono A; Sudol M; Holmgren L; Stanger BZ; Kissil JL
  • Article: NATURE COMMUNICATIONS. 2013;4:1672
    Hayashi M; Majumdar A; Li X; Adler J; Sun Z; Vertuani S; Hellberg C; Mellberg S; Koch S; Dimberg A; Koh GY; Dejana E; Belting H-G; Affolter M; Thurston G; Holmgren L; Vestweber D; Claesson-Welsh L
  • Article: CANCER CELL. 2011;19(4):527-540
    Yi C; Troutman S; Fera D; Stemmer-Rachamimov A; Avila JL; Christian N; Persson NL; Shimono A; Speicher DW; Marmorstein R; Holmgren L; Kissil JL

Artiklar

  • Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2024;43(1):107
    Fonseca P; Cui W; Struyf N; Tong L; Chaurasiya A; Casagrande F; Zhao H; Fernando D; Chen X; Tobin NP; Seashore-Ludlow B; Lundqvist A; Hartman J; Gondor A; Ostling P; Holmgren L
  • Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2024;44(3):666-689
    Mannion AJ; Zhao H; Zhang Y; von Wright Y; Bergman O; Roy J; Saharinen P; Holmgren L
  • Article: CELLS. 2023;12(17):2158
    Cui W; Subramani A; Fonseca P; Zhang Y; Tong L; Zhang Y; Egevad L; Lundqvist A; Holmgren L
  • Article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644
    Zhang Y; Zhang Y; Hutterer E; Hultin S; Bergman O; Kolbeinsdottir S; Jin H; Forteza MJ; Ketelhuth DFJ; Roy J; Hedin U; Enge M; Matic L; Eriksson P; Holmgren L
  • Article: CELLS. 2023;12(13):1682
    Subramani A; Cui W; Zhang Y; Friman T; Zhao Z; Huang W; Fonseca P; Lui W-O; Narayanan V; Bobrowska J; Lekka M; Yan J; Conway DEE; Holmgren L
  • Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2022;79(10):535
    Maeso-Alonso L; Alonso-Olivares H; Martinez-Garcia N; Lopez-Ferreras L; Villoch-Fernandez J; Puente-Santamaria L; Colas-Algora N; Fernandez-Corona A; Lorenzo-Marcos ME; Jimenez B; Holmgren L; Wilhelm M; Millan J; del Peso L; Claesson-Welsh L; Marques MM; Marin MC
  • Article: CELL REPORTS. 2021;36(8):109616
    Zhang Y; Zhang Y; Kameishi S; Barutello G; Zheng Y; Tobin NP; Nicosia J; Hennig K; Chiu DK-C; Balland M; Barker TH; Cavallo F; Holmgren L
  • Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(10):5508-5522
    Yang Y; Neo SY; Chen Z; Cui W; Chen Y; Guo M; Wang Y; Xu H; Kurzay A; Alici E; Holmgren L; Haglund F; Wang K; Lundqvist A
  • Article: PLOS BIOLOGY. 2019;17(5):e3000253
    Rojek KO; Krzemien J; Dolezyczek H; Boguszewski PM; Kaczmarek L; Konopka W; Rylski M; Jaworski J; Holmgren L; Proszynski TJ
  • Article: SCIENTIFIC REPORTS. 2017;7(1):9540
    Hildebrand S; Hultin S; Subramani A; Petropoulos S; Zhang Y; Cao X; Mpindi J; Kalloniemi O; Johansson S; Majumdar A; Lanner F; Holmgren L
  • Article: SCIENTIFIC REPORTS. 2017;7(1):7548
    Hultin S; Subramani A; Hildebrand S; Zheng Y; Majumdar A; Holmgren L
  • Article: ACS NANO. 2017;11(7):7110-7117
    Cao L; Nicosia J; Larouche J; Zhang Y; Bachman H; Brown AC; Holmgren L; Barker TH
  • Article: SCIENTIFIC REPORTS. 2016;6:30622
    Zheng Y; Zhang Y; Barutello G; Chiu K; Arigoni M; Giampietro C; Cavallo F; Holmgren L
  • Article: ONCOIMMUNOLOGY. 2015;4(5):e1005500
    Barutello G; Curcio C; Spadaro M; Arigoni M; Trovato R; Bolli E; Zheng Y; Ria F; Quaglino E; Iezzi M; Riccardo F; Holmgren L; Forni G; Cavallo F
  • Article: EJNMMI RESEARCH. 2014;4(1):17
    Samen E; Lu L; Mulder J; Thorell J-O; Damberg P; Tegnebratt T; Holmgren L; Rundqvist H; Stone-Elander S
  • Article: CIRCULATION. 2014;129(12):1295-1302
    Connolly-Andersen A-M; Hammargren E; Whitaker H; Eliasson M; Holmgren L; Klingstrom J; Ahlm C
  • Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(13):8991-9000
    Stalin J; Harhouri K; Hubert L; Subrini C; Lafitte D; Lissitzky J-C; Elganfoud N; Robert S; Foucault-Bertaud A; Kaspi E; Sabatier F; Aurrand-Lions M; Bardin N; Holmgren L; Dignat-George F; Blot-Chabaud M
  • Article: ANGIOGENESIS. 2012;15(2):305-316
    Arigoni M; Barutello G; Lanzardo S; Longo D; Aime S; Curcio C; Iezzi M; Zheng Y; Barkefors I; Holmgren L; Cavallo F
  • Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(7):811-820
    Zhang X; Zheng Y; Fried LE; Du Y; Montano SJ; Sohn A; Lefkove B; Holmgren L; Arbiser JL; Holmgren A; Lu J
  • Article: MOLECULAR CANCER RESEARCH. 2010;8(9):1198-1206
    Zaslavsky A; Chen C; Grillo J; Baek K-H; Holmgren L; Yoon SS; Folkman J; Ryeom S
  • Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):147-151
    Holmgren L
  • Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36(8):1283-1295
    Samen E; Thorell J-O; Lu L; Tegnebratt T; Holmgren L; Stone-Elander S
  • Article: CIRCULATION RESEARCH. 2009;105(3):260-270
    Zheng Y; Vertuani S; Nystrom S; Audebert S; Meijer I; Tegnebratt T; Borg J-P; Uhlen P; Majumdar A; Holmgren L
  • Article: CELL DEATH AND DIFFERENTIATION. 2009;16(5):749-757
    Ehnfors J; Kost-Alimova M; Persson NL; Bergsmedh A; Castro J; Levchenko-Tegnebratt T; Yang L; Panaretakis T; Holmgren L
  • Article: BLOOD. 2009;113(1):244-253
    Ernkvist M; Persson NL; Audebert S; Lecine P; Sinha I; Liu M; Schlueter M; Horowitz A; Aase K; Weide T; Borg J-P; Majumdar A; Holmgren L
  • Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2008;1783(3):429-437
    Ernkvist M; Birot O; Sinha I; Veitonmaki N; Nystrom S; Aase K; Holmgren L
  • Article: THE FASEB JOURNAL. 2008;22(3):880-889
    Levchenko T; Veitonmaeki N; Lundkvist A; Gerhardt H; Ming Y; Berggren K; Kvanta A; Carlsson R; Holmgren L
  • Article: GENES & DEVELOPMENT. 2007;21(16):2055-2068
    Aase K; Ernkvist M; Ebarasi L; Jakobsson L; Majumdar A; Yi C; Birot O; Ming Y; Kvanta A; Edholm D; Aspenstrom P; Kissil J; Claesson-Welsh L; Shimono A; Holmgren L
  • Article: FEBS LETTERS. 2007;581(16):2943-2946
    Bergsmedh A; Ehnfors J; Spetz A-L; Holmgren L
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(24):9208-9213
    Holmgren L; Ambrosino E; Birot O; Tullus C; Veitonmaki N; Levchenko T; Carlson L-M; Musiari P; Iezzi M; Curcio C; Forni G; Cavallo F; Kiessling R
  • Article: THE FEBS JOURNAL. 2006;273(9):2000-2011
    Ernkvist M; Aase K; Ukomadu C; Wohlschlegel J; Blackman R; Veitonmäki N; Bratt A; Dutta A; Holmgren L
  • Article: MOLECULAR CANCER RESEARCH. 2006;4(3):187-195
    Bergsmedh A; Ehnfors J; Kawane K; Motoyama N; Nagata S; Holmgren L
  • Article: BMC CANCER. 2006;6:16
    Jiang WG; Watkins G; Douglas-Jones A; Holmgren L; Mansel RE
  • Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(41):34859-34869
    Bratt A; Birot O; Sinha I; Veitonmäki N; Aase K; Ernkvist M; Holmgren L
  • Article: ONCOGENE. 2004;23(7):1469-1473
    Levchenko T; Bratt A; Arbiser JL; Holmgren L
  • Article: JOURNAL OF CELL SCIENCE. 2003;116(18):3803-3810
    Levchenko T; Aase K; Troyanovsky B; Bratt A; Holmgren L
  • Article: ANNALS OF SURGERY. 2003;237(4):530-535
    Greene AK; Wiener S; Puder M; Yoshida A; Shi B; Perez-Atayde AR; Efstathiou JA; Holmgren L; Adamis AP; Rupnick M; Folkman J; O'Reilly MS
  • Article: MOLECULAR AND CELLULAR BIOLOGY. 2003;23(4):1260-1268
    Antonson P; Schuster GU; Wang L; Rozell B; Holter E; Flodby P; Treuter E; Holmgren L; Gustafsson J
  • Article: JOURNAL OF IMMUNOLOGY. 2002;169(10):5771-5779
    Spetz AL; Sörensen AS; Walther-Jallow L; Wahren B; Andersson J; Holmgren L; Hinkula J
  • Article: GENE. 2002;298(1):69-77
    Bratt A; Wilson WJ; Troyanovsky B; Aase K; Kessler R; Van Meir EG; Holmgren L
  • Article: CANCER RESEARCH. 2002;62(2):575-579
    Bergsmedh A; Szeles A; Spetz AL; Holmgren L
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(11):6407-6411
    Bergsmedh A; Szeles A; Henriksson M; Bratt A; Folkman MJ; Spetz AL; Holmgren L
  • Article: JOURNAL OF CELL BIOLOGY. 2001;152(6):1247-1254
    Troyanovsky B; Levchenko T; MÃ¥nsson G; Matvijenko O; Holmgren L
  • Article: JOURNAL OF IMMUNOLOGY. 1999;163(2):736-742
    Spetz AL; Patterson BK; Lore K; Andersson J; Holmgren L
  • Article: BLOOD. 1999;93(11):3956-3963
    Holmgren L; Szeles A; Rajnavölgyi E; Folkman J; Klein G; Ernberg I; Falk KI
  • Article: ANGIOGENESIS. 1999;3(4):291-293
    Lenander C; Holmgren L
  • Article: BLOOD. 1998;92(12):4730-4741
    Lucas R; Holmgren L; Garcia I; Jimenez B; Mandriota SJ; Borlat F; Sim BKL; Wu Z; Grau GE; Shing Y; Soff GA; Bouck N; Pepper MS
  • Article: ONCOGENE. 1998;17(7):819-824
    Holmgren L; Jackson G; Arbiser J
  • Article: NATURE MEDICINE. 1996;2(6):689-692
    OReilly MS; Holmgren L; Chen C; Folkman J
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(5):2002-2007
    Parangi S; O'Reilly M; Christofori G; Holmgren L; Grosfeld J; Folkman J; Hanahan D
  • Article: NATURE MEDICINE. 1995;1(2):149-153
    Holmgren L; O'Reilly MS; Folkman J
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Alla övriga publikationer

  • Review: DISEASE MODELS & MECHANISMS. 2023;16(10):dmm050361
    Mannion AJ; Holmgren L
  • Corrigendum: GENE. 2003;310:221
    Bratt A; Wilson WJ; Troyanovsky B; Aase K; Kessler R; Van Meir EG; Holmgren L
  • Published conference paper: VOX SANGUINIS. 2002;83:305-306
    Holmgren L; Bergsmedh A; Spetz AL
  • Review: CANCER AND METASTASIS REVIEWS. 1996;15(2):241-245
    Holmgren L

´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù

  • Professor, Onkologi-Patologi, ̽»¨¾«Ñ¡, 2008-

Examina och utbildning

  • Docent, Tumörbiologi, ̽»¨¾«Ñ¡, 1998

Uppdrag

  • Prefekt, Onkologi-Patologi, ̽»¨¾«Ñ¡, 2021-

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