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Johan Högberg

Johan Högberg

Professor | Docent
E-postadress: johan.hogberg@ki.se
Telefon: +46852487783
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: Nobels väg 13, 17177 Stockholm
Postadress: C6 Institutet för miljömedicin, C6 Biokemisk toxikologi Stenius, 171 77 Stockholm

Om mig

  • Ongoing research projects:
    - Gender differences in carcinogenesis (supported by Formas)
    - Low-dose genotoxic effects of crystalline silica particles (supported
    by AFA).

    - New type of DNA damage induced by chrystalline siliuca particles: does anti-androgenic carcinogens increase men´s sensitivity ti silica? (supported by Forte 2025 - 2027).

     

Forskningsbeskrivning

  • Recent selected publications:
    Approaches for the setting of occupational exposure limits (OELs) for
    carcinogens. [1]
    *Högberg J*, Järnberg J.Crit Rev Toxicol. 2023 Dec
  • 53(3):131-167. doi:
    10.1080/10408444.2023.2218887. Epub 2023 Jun 27.PMID: 37366107 Review
    ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory
    Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline
    Silica Particles. [2]
    Zheng H, Stenius U, *Högberg J.*Cancers (Basel). 2023 Jan 30
  • 15(3):865.
    doi: 10.3390/cancers15030865.PMID: 36765823.
    Application of Text Mining in Risk Assessment of Chemical Mixtures: A Case
    Study of Polycyclic Aromatic Hydrocarbons (PAHs). [3]
    Ali I, Dreij K, Baker S, *Högberg J*, Korhonen A, Stenius U.Environ Health
    Perspect. 2021 Jun
  • 129(6):67008. doi: 10.1289/EHP6702. Epub 2021 Jun
    24.PMID: 34165340.
    Crystalline silica particles induce DNA damage in respiratory epithelium by
    ATX secretion and Rac1 activation. [4]
    Wu R, *Högberg J*, Adner M, Stenius U, Zheng H.Biochem Biophys Res Commun.
    2021 Apr 9
  • 548:91-97. doi: 10.1016/j.bbrc.2021.02.020. Epub 2021 Feb
    23.PMID: 33636640.
    Crystalline silica particles cause rapid NLRP3-dependent mitochondrial
    depolarization and DNA damage in airway epithelial cells. [5]
    Wu R, *Högberg J*, Adner M, Ramos-Ramírez P, Stenius U, Zheng H.Part Fibre
    Toxicol. 2020 Aug 10
  • 17(1):39. doi:
    10.1186/s12989-020-00370-2.PMID: 32778128.
    [1]
    [2]
    [3]
    [4]
    [5]

Artiklar

  • Article: CANCERS. 2023;15(3):865
    Zheng H; Stenius U; Hoegberg J
  • Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2021;129(6):67008
    Ali I; Dreij K; Baker S; Hogberg J; Korhonen A; Stenius U
  • Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;548:91-97
    Wu R; Hogberg J; Adner M; Stenius U; Zheng H
  • Article: JOURNAL OF IMMUNOTOXICOLOGY. 2021;18(1):74-84
    Karri V; Liden C; Fyhrquist N; Hogberg J; Karlsson HL
  • Article: PARTICLE AND FIBRE TOXICOLOGY. 2020;17(1):39
    Wu R; Hogberg J; Adner M; Ramos-Ramirez P; Stenius U; Zheng H
  • Article: BIOMEDICINE & PHARMACOTHERAPY. 2020;127:110112
    Ghalali A; Ye Z-W; Hogberg J; Stenius U
  • Article: BIOINFORMATICS. 2019;35(9):1553-1561
    Pyysalo S; Baker S; Ali I; Haselwimmer S; Shah T; Young A; Guo Y; Hogberg J; Stenius U; Narita M; Korhonen A
  • Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2018;355:43-51
    Brostrom JM; Ghalali A; Zheng H; Hogberg J; Stenius U; Littorin M; Tinnerberg H; Broberg K
  • Article: BIOINFORMATICS. 2017;33(24):3973-3981
    Baker S; Ali I; Silins I; Pyysalo S; Guo Y; Hogberg J; Stenius U; Korhonen A
  • Article: CARCINOGENESIS. 2017;38(12):1196-1206
    Zheng H; Hogberg J; Stenius U
  • Article: MOLECULAR CANCER RESEARCH. 2017;15(6):714-722
    Ghalali A; Martin-Renedo J; Hogberg J; Stenius U
  • Article: CARCINOGENESIS. 2016;37(12):1144-1151
    Ali I; Julin B; Glynn A; Hogberg J; Berglund M; Johansson J-E; Andersson S-O; Andren O; Giovannucci E; Wolk A; Stenius U; Akesson A
  • Article: CARCINOGENESIS. 2016;37(10):985-992
    Ali I; Hogberg J; Hsieh J-H; Auerbach S; Korhonen A; Stenius U; Silins I
  • Article: BIOINFORMATICS. 2016;32(3):432-440
    Baker S; Silins I; Guo Y; Ali I; Hogberg J; Stenius U; Korhonen A
  • Article: TOXICOLOGY LETTERS. 2016;241:32-37
    Ali I; Guo Y; Silins I; Hogberg J; Stenius U; Korhonen A
  • Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2015;287(3):222-231
    Brostrom JM; Ye Z-W; Axmon A; Littorin M; Tinnerberg H; Lindh CH; Zheng H; Ghalali A; Stenius U; Jonsson BAG; Hogberg J
  • Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2015;239:164-173
    Al-Anati L; Viluksela M; Strid A; Bergman A; Andersson PL; Stenius U; Hogberg J
  • Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2014;219:159-167
    Al-Anati L; Kadekar S; Hogberg J; Stenius U
  • Article: CARCINOGENESIS. 2014;35(7):1547-1555
    Ghalali A; Wiklund F; Zheng H; Stenius U; Hogberg J
  • Article: TOXICOLOGIC PATHOLOGY. 2012;40(8):1160-1168
    Kadekar S; Peddada S; Silins I; French JE; Hogberg J; Stenius U
  • Article: JOURNAL OF RADIOLOGICAL PROTECTION. 2012;32(4):439-446
    Högberg J; Rizell M; Hultborn R; Svensson J; Henrikson O; Gjertsson P; Bernhardt P
  • Article: INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT. 2012;8(3):412-417
    Silins I; Korhonen A; Hogberg J; Stenius U
  • Article: CLINICA CHIMICA ACTA. 2012;413(7-8):727-732
    Leander K; Gigante B; Silveira A; Vikstrom M; Hamsten A; Hogberg J
  • Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2012;40(3):867-875
    Miraglia E; Hogberg J; Stenius U
  • Article: PLOS ONE. 2012;7(4):e33427
    Korhonen A; Seaghdha DO; Silins I; Sun L; Hogberg J; Stenius U
  • Article: PLOS ONE. 2012;7(8):e43209
    Kadekar S; Silins I; Korhonen A; Dreij K; Al-Anati L; Hogberg J; Stenius U
  • Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;415(4):613-618
    Ye Z-W; Ghalali A; Hogberg J; Stenius U
  • Article: BMC BIOINFORMATICS. 2011;12:69
    Guo Y; Korhonen A; Liakata M; Silins I; Hogberg J; Stenius U
  • Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2010;249(2):166-177
    Al-Anati L; Hogberg J; Stenius U
  • Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(36):27900-27910
    Mistafa O; Ghalali A; Kadekar S; Hogberg J; Stenius U
  • Article: CHEMICO-BIOLOGICAL INTERACTIONS. 2009;182(2-3):191-198
    Al-Anati L; Hogberg J; Stenius U
  • Article: TOXICOLOGICAL SCIENCES. 2008;102(2):232-240
    Malmlof M; Paajarvi G; Hogberg J; Stenius U
  • Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2008;116(3):334-339
    Hogberg J; Hanberg A; Berglund M; Skerfving S; Remberger M; Calafat AM; Filipsson AF; Jansson B; Johansson N; Appelgren M; Hakansson H
  • Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2008;365(1):131-136
    Mistafa O; Hoegberg J; Stenius U
  • Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(4):2288-2296
    Malmlof M; Roudier E; Hogberg J; Stenius U
  • Article: FOOD AND CHEMICAL TOXICOLOGY. 2006;44(9):1552-1561
    Silins I; Hogberg J; Stenius U
  • Article: THE FASEB JOURNAL. 2005;18(15):476-478
    Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
  • Article: CARCINOGENESIS. 2005;26(1):201-208
    Pääjärvi G; Viluksela M; Pohjanvirta R; Stenius U; Högberg J
  • Article: ARCHIVES OF TOXICOLOGY. 2004;78(9):540-548
    Silins I; Stenius U; Högberg J
  • Article: ANNALS OF OCCUPATIONAL HYGIENE. 2004;48(4):339-349
    Svedberg URA; Högberg HE; Högberg J; Galle B
  • Article: CANCER LETTERS. 2004;207(2):149-155
    Finnberg N; Stenius U; Högberg J
  • Article: CARCINOGENESIS. 2004;25(1):113-122
    Finnberg N; Silins I; Stenius U; Högberg J
  • Article: CARCINOGENESIS. 2003;24(6):1077-1083
    Silins I; Nordstrand M; Högberg J; Stenius U
  • Article: CARCINOGENESIS. 2001;22(12):2023-2031
    Silins I; Finnberg N; Ståhl A; Högberg J; Stenius U
  • Article: TOXICOLOGICAL SCIENCES. 2000;54(1):95-103
    Finnberg N; Stenius U; Högberg J
  • Article: HYBRIDOMA. 2000;19(1):63-72
    Thullberg M; Welcker M; Bartkova J; Kjerulff AA; Lukas J; Högberg J; Bartek J
  • Article: CELL BIOLOGY AND TOXICOLOGY. 1999;15(1):31-39
    Lennartsson P; Stenius U; Högberg J
  • Article: CANCER LETTERS. 1998;134(1):103-109
    Stenius U; Högberg J
  • Journal article: TOXICOLOGY LETTERS. 1998;95:180
    Stenius U; Lennartsson P; Högberg J
  • Article: CARCINOGENESIS. 1998;19(7):1231-1237
    Lennartsson P; Högberg J; Stenius U
  • Article: CANCER LETTERS. 1998;128(1):1-10
    Thullberg M; Grasl-Kraupp B; Högberg J; Garberg P
  • Article: TOXICOLOGY IN VITRO. 1998;12(3):279-285
    Stenius U; Stahl A; Hogberg J
  • Article: CANCER LETTERS. 1996;104(1):21-26
    Martens U; Lennartsson P; Högberg J; Stenius U
  • Article: TOXICOLOGY IN VITRO. 1995;9(6):937-943
    Warholm M; Stenius U; Ståhl A; Högberg J
  • Journal article: EPIDEMIOLOGY. 1995;6(2):s47
    Högberg J; Alexandrie AK; Sigvardsson K; Warholm M; Rannug A
  • Journal article: PHARMACOGENETICS AND GENOMICS. 1994;4(6):307-312
    Warholm M; Alexandrie AK; Högberg J; Sigvardsson K; Rannug A
  • Journal article: CARCINOGENESIS. 1994;15(8):1561-1566
    Stenius U; Warholm M; Martens U; Högberg J
  • Journal article: CARCINOGENESIS. 1990;11(1):69-73
    Stenius U; Rubin K; Gullberg D; Högberg J
  • Journal article: CARCINOGENESIS. 1989;10(3):593-599
    Stenius U; Warholm M; Rannug A; Walles S; Lundberg I; Högberg J
  • Journal article: BIOCHEMICAL PHARMACOLOGY. 1988;37(18):3401-3406
    Garberg P; Ståhl A; Warholm M; Högberg J
  • Journal article: CARCINOGENESIS. 1988;9(7):1223-1228
    Stenius U; Högberg J
  • Journal article: CHEMICO-BIOLOGICAL INTERACTIONS. 1988;67(1-2):25-31
    Ekström T; Warholm M; Kronevi T; Högberg J
  • Journal article: CHEMICO-BIOLOGICAL INTERACTIONS. 1988;66(3-4):177-187
    EKSTROM T; GARBERG P; EGESTAD B; HOGBERG J
  • Journal article: CANCER LETTERS. 1987;36(1):29-33
    Lundberg I; Högberg J; Kronevi T; Holmberg B
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Alla övriga publikationer

  • Review: CRITICAL REVIEWS IN TOXICOLOGY. 2023;53(3):131-167
    Hogberg J; Jarnberg J
  • Letter: EXCLI JOURNAL. 2020;19:490-491
    Hogberg J
  • Corrigendum: CHEMICO-BIOLOGICAL INTERACTIONS. 2017;268:148
    Al-Anati L; Kadekar S; Hogberg J; Stenius U
  • Corrigendum: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(51):26588
    Malmlöf M; Roudier E; Högberg J; Stenius U
  • Review: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2011;8(3):629-647
    Silins I; Hogberg J
  • Conference publication: CANCER RESEARCH. 2010;70:1687
    Kadekar S; Silins I; Hogberg J; Dreij K; Stenius U
  • Conference publication: EUROPEAN HEART JOURNAL. 2010;31:537
    Leander K; Gigante B; Hogberg J
  • Meeting abstract: EPIDEMIOLOGY. 2009;20(6):S175
    Grelher J; Gasparrini A; Merilainen P; Villanueva C; Kuhn A; Fletcher T; Vartiainen T; Kogevinas M; Hogberg J; Bernard A; Nieuwenhuijsen M
  • Review: EXS. 2009;99:181-208
    Högberg J; Silins I; Stenius U
  • Conference publication: CANCER RESEARCH. 2009;69
    Silins I; Korhonen A; Hogberg J; Sun L; Stenius U
  • Meeting abstract: EPIDEMIOLOGY. 2006;17(6):S299
    Hogberg J; Stenius U; Paajarvi G
  • Conference publication: CANCER RESEARCH. 2006;66(8)
    Stenius U; Roudier E; Mistafa O; Hogberg J
  • Letter: CRITICAL REVIEWS IN TOXICOLOGY. 2005;35(5):459-460
    Högberg J; Larsson K; Albin M; Järvholm B; Montelius J
  • Corrigendum: ANNALS OF OCCUPATIONAL HYGIENE. 2004;48(4):381
    Svedberg URA; Högberg HR; Högberg J; Galle B
  • Conference publication: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2002;11(10):1213S
    Högberg J; Stenius U; Silins I
  • Letter: HEPATOLOGY. 2001;33(2):480-481
    Högberg J; Stenius U
  • Letter: CARCINOGENESIS. 1999;20(1):181-182
    Stenius U; Högberg J
  • Published conference paper: TOXICOLOGY IN VITRO. 1998;12(5):607-610
    Lennartsson P; Stenius U; Hogberg J
  • Published conference paper: ATLA ALTERNATIVES TO LABORATORY ANIMALS. 1996;24(3):393-397
    Stenius U; Martens U; Hogberg J
  • Other: CARCINOGENESIS. 1995;16(8):1683-1686
    Stenius U; Högberg J
  • Book chapter: SELENIUM IN BIOLOGY AND MEDICINE. 1989;p. 74-78
    Högberg J; Garberg P; Ståhl A
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Forskningsbidrag

  • Swedish Research Council for Environment Agricultural Sciences and Spatial Planning
    1 January 2023 - 31 December 2025
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2019 - 31 December 2021

´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù

  • Professor, Institutet för miljömedicin, ̽»¨¾«Ñ¡, 2021-

Examina och utbildning

  • Docent, Rättsmedicin, ̽»¨¾«Ñ¡, 1978

Nyheter från KI

Kalenderhändelser från KI