̽»¨¾«Ñ¡

Gilberto Fisone

Gilberto Fisone

Professor | Prefekt
E-postadress: gilberto.fisone@ki.se
Telefon: +46852487375
µþ±ð²õö°ì²õ²¹»å°ù±ð²õ²õ: , Solna
Postadress: C4 Neurovetenskap, C4 Forskning Fisone, 171 77 Stockholm
Del av:

Om mig

  • Utbildning
    1990              Ph.D. Stockholm University.
    1991-1994      Postdoctoral Fellow, The Rockefeller University, New York.
    1994-1995     Assistant Professor, The Rockefeller University, New York.
    1996-2000    Assistant Professor, Department of Neuroscience, ̽»¨¾«Ñ¡.
    2000-2006  Associate Professor, Department of Neuroscience, ̽»¨¾«Ñ¡.
    From 2006   Professor of Neuroscience, Department of Neuroscience, ̽»¨¾«Ñ¡.
    From 2010    Member of the Executive Board at the Department of Neuroscience, ̽»¨¾«Ñ¡.
    From 2012    Director of Studies at the Department of Neuroscience, ̽»¨¾«Ñ¡.

    From 2018    Chair, Department of Neuroscience, ̽»¨¾«Ñ¡. 

    Akademiska priser och utmärkelser

    2022-present: Member of Academia Europaea.

    2022-present: Secretary, International Basal Ganglia Society (IBAGS).

    2020-present: Board of the Swedish Basal Ganglia Society (SWEBAGS).

    2018-present: Scientific Advisory Board, Neuroscience Inst. Cavaliere Ottolenghi, Turin, Italy.

    2018-present: Scientific Committee, Dargut and Milena Kemali Foundation

    2018-present:    Chair, Department of Neuroscience, ̽»¨¾«Ñ¡. 

    2014-present: International Union of Basic and Clinical Pharmacology (IUPHAR) Subcommittee on Dopamine Receptors

Forskningsbeskrivning

  • Vi studerar signaltransduktionsmekanismerna involverade i neurodegenerativa och psykiatriska sjukdomar, som Parkinsons sjukdom, schizofreni och drogberoende. Vi är speciellt intresserade pÃ¥ av dopamintransmission, som är djupt pÃ¥verkad vid dessa patologier.

    Vårt slutmål är att identifiera molekylära ändringar som representerar nya måltavlor för terapeutiska behandlingar. Metodologin är baserad på en kombination av molekylärbiologiska, biokemiska och beteendestuderande tekniker. Med denna strategi har vi karakteriserat viktiga mekanismer involverade i effekterna av många psykoaktiva substanser, som koffein, morfin, cannabis och antipsykotiska läkemedel.

    I andra studier, har vi identifierat ändringar i signaltransduktion kopplade till de svåra rörelserubbningar, s.k. dyskinesi, som drabbar Parkinsons patienter under behandling med levodopa. Slutligen studerar vi också de kognitiva och psykiatriska symptomer som ofta uppkommer vid Parkinsons sjukdom.

Artiklar

  • Journal article: MOLECULAR PSYCHIATRY. 2025;30(3):976-985
    Plewnia C; Masini D; Fisone G
  • Article: HELIYON. 2024;10(16):e35948
    Medeiros D; Masini D; Plewnia C; Boi L; Rosati M; Scalbert N; Fisone G
  • Journal article: ELIFE. 2024;12
    Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
  • Article: PROGRESS IN NEUROBIOLOGY. 2023;231:102536
    Medeiros DDC; Plewnia C; Mendes RV; Pisano CA; Boi L; Moraes MFD; Aguiar CL; Fisone G
  • Article: NATURE COMMUNICATIONS. 2022;13(1):5944
    Korchynska S; Rebernik P; Pende M; Boi L; Alpar A; Tasan R; Becker K; Balueva K; Saghafi S; Wulff P; Horvath TL; Fisone G; Dodt H-U; Hokfelt T; Harkany T; Romanov RA
  • Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(19):11637
    Onimus O; Valjent E; Fisone G; Gangarossa G
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(7):e2108768119
    Smedler E; Louhivuori L; Romanov RA; Masini D; Ellstrom ID; Wang C; Caramia M; West Z; Zhang S; Rebellato P; Malmersjo S; Brusini I; Kanatani S; Fisone G; Harkany T; Uhlen P
  • Article: BIOMEDICINES. 2021;9(6):598
    Masini D; Plewnia C; Bertho M; Scalbert N; Caggiano V; Fisone G
  • Article: MOVEMENT DISORDERS. 2021;36(5):1137-1146
    Feyder M; Plewnia C; Lieberman OJ; Spigolon G; Piccin A; Urbina L; Dehay B; Li Q; Nilsson P; Altun M; Santini E; Sulzer D; Bezard E; Borgkvist A; Fisone G
  • Article: CELLULAR AND MOLECULAR NEUROBIOLOGY. 2021;41(1):191-198
    Zattoni M; Garrovo C; Xerxa E; Spigolon G; Fisone G; Kristensson K; Legname G
  • Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29(5):616-628
    Adem A; Madjid N; Stiedl O; Bonito-Oliva A; Konradsson-Geuken A; Holst S; Fisone G; Ogren SO
  • Article: FRONTIERS IN NEUROSCIENCE. 2019;13:683
    Falconi A; Bonito-Oliva A; Di Bartolomeo M; Massimini M; Fattapposta F; Locuratolo N; Dainese E; Pascale E; Fisone G; D'Addario C
  • Article: NATURE NEUROSCIENCE. 2018;21(6):834-842
    Stagkourakis S; Spigolon G; Williams P; Protzmann J; Fisone G; Broberger C
  • Article: NEUROBIOLOGY OF DISEASE. 2018;110:37-46
    Spigolon G; Cavaccini A; Trusel M; Tonini R; Fisone G
  • Article: NATURE. 2018;553(7689):455-460
    Caggiano V; Leiras R; Goni-Erro H; Masini D; Bellardita C; Bouvier J; Caldeira V; Fisone G; Kiehn O
  • Article: FRONTIERS IN NEUROLOGY. 2018;9:208
    Masini D; Bonito-Oliva A; Bertho M; Fisone G
  • Article: NATURE NEUROSCIENCE. 2018;21(1):139-149
    Furth D; Vaissiere T; Tzortzi O; Xuan Y; Martin A; Lazaridis I; Spigolon G; Fisone G; Tomer R; Deisseroth K; Carlen M; Miller CA; Rumbaugh G; Meletis K
  • Article: NATURE COMMUNICATIONS. 2017;8(1):293
    Briz V; Restivo L; Pasciuto E; Juczewski K; Mercaldo V; Lo AC; Baatsen P; Gounko NV; Borreca A; Girardi T; Luca R; Nys J; Poorthuis RB; Mansvelder HD; Fisone G; Ammassari-Teule M; Arckens L; Krieger P; Meredith R; Bagni C
  • Article: NEURON. 2017;94(4):855-865.e5
    Ketzef M; Spigolon G; Johansson Y; Bonito-Oliva A; Fisone G; Silberberg G
  • Article: NATURE BIOTECHNOLOGY. 2017;35(5):444-452
    Cervo PRDV; Romanov RA; Spigolon G; Masini D; Martin-Montanez E; Toledo EM; La Manno G; Feyder M; Pifl C; Ng Y-H; Sanchez SP; Linnarsson S; Wernig M; Harkany T; Fisone G; Arenas E
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Alla övriga publikationer

  • Preprint: ELIFE. 2024
    Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
  • Preprint: BIORXIV. 2024;BIORXIV
    Stagkourakis S; Williams P; Spigolon G; Khanal S; Ziegler K; Heikkinen L; Fisone G; Broberger C
  • Book chapter: TRANSLATIONAL APPROACHES TO UNRAVELLING NON-MOTOR SYMPTOMS OF PARKINSON'S DISEASE: INTERNATIONAL REVIEW OF NEUROBIOLOGY. 2024;p. 119-186
    Boi L; Fisone G
  • Review: FRONTIERS IN PHARMACOLOGY. 2019;10:1414
    Medeiros DDC; Aguiar CL; Dutra Moraes MF; Fisone G
  • Review: JOURNAL OF NEURAL TRANSMISSION. 2018;125(8):1171-1186
    Spigolon G; Fisone G
  • Review: PROGRESS IN NEUROBIOLOGY. 2015;132:96-168
    Bastide MF; Meissner WG; Picconi B; Fasano S; Fernagut P-O; Feyder M; Francardo V; Alcacer C; Ding Y; Brambilla R; Fisone G; Stoessl AJ; Bourdenx M; Engeln M; Navailles S; De Deurwaerdere P; Ko WKD; Simola N; Morelli M; Groc L; Rodriguez M-C; Gurevich EV; Quik M; Morari M; Mellone M; Gardoni F; Tronci E; Guehl D; Tison F; Crossman AR; Kang UJ; Steece-Collier K; Fox S; Carta M; Cenci MA; Bezard E
  • Book chapter: DOPAMINE RECEPTOR TECHNOLOGIES: NEUROMETHODS. 2015;p. 79-100
    Bonito-Oliva A; Spigolon G; Fisone G
  • Editorial comment: CURRENT PROTEIN & PEPTIDE SCIENCE. 2014;15(7):647
    Fuxe K; Borroto-Escuela D; Fisone G; Agnati LF; Tanganelli S
  • Review: LEARNING & MEMORY. 2013;20(10):592-600
    Solari N; Bonito-Oliva A; Fisone G; Brambilla R
  • Review: NEUROPHARMACOLOGY. 2013;66:53-64
    Amalric M; Lopez S; Goudet C; Fisone G; Battaglia G; Nicoletti F; Pin J-P; Acher FC
  • Editorial comment: FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 2012;6:72
    Fisone G; Brambilla R
  • Editorial comment: PARKINSONS DISEASE. 2012;2012:639080-2
    Carta AR; Giuffrida A; Fisone G
  • Review: FRONTIERS IN NEUROANATOMY. 2011;5:38
    Bonito-Oliva A; Feyder M; Fisone G
  • Review: INTERNATIONAL REVIEW OF NEUROBIOLOGY. 2011;98:95-122
    Fisone G; Bezard E
  • Editorial comment: EXPERIMENTAL NEUROLOGY. 2010;226(1):11-14
    Fisone G
  • Review: TRENDS IN NEUROSCIENCES. 2009;32(10):538-547
    Valjent E; Bertran-Gonzalez J; Herve D; Fisone G; Girault J-A
  • Review: FEBS JOURNAL. 2008;275(7):1392-1399
    Santini E; Valjent E; Fisone G
  • Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2008;18:S5-S6
    Borgkvist A; Nestler EJ; Greengard P; Fisone G; Brene S
  • Published conference paper: PROGRESS IN NEUROBIOLOGY. 2007;83(5):277-292
    Schiffmann SN; Fisone G; Moresco R; Cunha RA; Ferre S
  • Published conference paper: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2007;31(1):79-88
    Borgkvist A; Fisone G
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´¡²Ô²õ³Ùä±ô±ô²Ô¾±²Ô²µ²¹°ù

  • Professor, Neurovetenskap, ̽»¨¾«Ñ¡, 2006-

Uppdrag

  • Prefekt, Neurovetenskap, ̽»¨¾«Ñ¡, 2021-

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