探花精选

Diana Pascal

Diana Pascal

Anknuten till Forskning | Docent
E-postadress: diana.pascal@ki.se
叠别蝉枚办蝉补诲谤别蝉蝉: M48, Karolinska Universitetssjukhuset Huddinge, 14186 Stockholm
Postadress: K8 Klinisk neurovetenskap, K8 CPF R眉ck, 171 77 Stockholm
Del av:

Utvalda publikationer

  • Article: BRAIN AND BEHAVIOR. 2023;13(8):e3115
    Chen LL; Abbaspour A; Aspvall K; R眉ck C; Bulik CM; Pascal D
  • Preprint: MEDRXIV. 2023;MEDRXIV
    Chen LL; Naesstr枚m M; Halvorsen M; Fytagoridis A; Mataix-Cols D; R眉ck C; Crowley JJ; Pascal D
  • Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2023;31:100608
    Lundstrom L; Flygare O; Ivanova E; Mataix-Cols D; Enander J; Pascal D; Chen L-L; Andersson E; Ruck C
  • Article: CNS SPECTRUMS. 2023;28(1):33-40
    Chen LL; Flygare O; Wallert J; Enander J; Ivanov VZ; Ruck C; Djurfeldt D
  • Article: PSYCHOSOMATIC MEDICINE. 2021;83(7):679-692
    Chen LL; Abbaspour A; Mkoma GF; Bulik CM; Ruck C; Djurfeldt D
  • Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2021;63(8):963-968
    Visser JE; Cotton AC; Schretlen DJ; Bloch J; Tedroff K; Schechtmann G; Djurfeldt DR; Gonzalez V; Cif L; Jinnah HA
  • Article: MOLECULAR PSYCHIATRY. 2021;26(4):1234-1247
    Menchon JM; Real E; Alonso P; Aparicio MA; Segalas C; Plans G; Luyten L; Brunfaut E; Matthijs L; Raymakers S; Bervoets C; Higueras A; Katati M; Guerrero J; Hurtado M; Prieto M; Stieglitz LH; Loffelholz G; Walther S; Pollo C; Zurowski B; Tronnier V; Kordon A; Gambini O; Ranieri R; Franzini A; Messina G; Radu-Djurfeldt D; Schechtmann G; Chen L-L; Eitan R; Israel Z; Bergman H; Brelje T; Brionne TC; Conseil A; Gielen F; Schuepbach M; Nuttin B; Gabriels L
  • Article: MOLECULAR PSYCHIATRY. 2021;26(1):60-65
    Wu H; Hariz M; Visser-Vandewalle V; Zrinzo L; Coenen VA; Sheth SA; Bervoets C; Naesstrom M; Blomstedt P; Coyne T; Hamani C; Slavin K; Krauss JK; Kahl KG; Taira T; Zhang C; Sun B; Toda H; Schlaepfer T; Chang JW; Regis J; Schuurman R; Schulder M; Doshi P; Mosley P; Poologaindran A; Lazaro-Munoz G; Pepper J; Schechtmann G; Fytagoridis A; Huys D; Goncalves-Ferreira A; D'haese P-F; Neimat J; Broggi G; Vilela-Filho O; Voges J; Alkhani A; Nakajima T; Richieri R; Djurfeldt D; Fontaine P; Martinez-Alvarez R; Okamura Y; Chandler J; Watanabe K; Barcia JA; Reneses B; Lozano A; Gabriels L; De Salles A; Halpern CH; Matthews K; Fins JJ; Nuttin B
  • Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2020;183(1):38-50
    Mataix-Cols D; Hansen B; Mattheisen M; Karlsson EK; Addington AM; Boberg J; Djurfeldt DR; Halvorsen M; Lichtenstein P; Solem S; Lindblad-Toh K; Haavik J; Kvale G; Ruck C; Crowley JJ; Noh HJ; Kahler AK; de Schipper E; Zayats T
  • Article: NATURE COMMUNICATIONS. 2017;8(1):774
    Noh HJ; Tang R; Flannick J; O'Dushlaine C; Swofford R; Howrigan D; Genereux DP; Johnson J; van Grootheest G; Grunblatt E; Andersson E; Djurfeldt DR; Patel PD; Koltookian M; Hultman CM; Pato MT; Pato CN; Rasmussen SA; Jenike MA; Hanna GL; Stewart SE; Knowles JA; Ruhrmann S; Grabe H-J; Wagner M; Ruck C; Mathews CA; Walitza S; Cath DC; Feng G; Karlsson EK; Lindblad-Toh K
  • Article: PSYCHOPHARMACOLOGY. 2003;166(2):139-145
    Radu D; 脜hlin A; Svanborg P; Lindefors N

Artiklar

  • Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2024;195(8):e32983
    Chen LL; Naesstrom M; Halvorsen M; Fytagoridis A; Crowley SB; Mataix-Cols D; Ruck C; Crowley JJ; Pascal D
  • Article: MOLECULAR PSYCHIATRY. 2024;30(4):1510-1517
    Halvorsen MW; de Schipper E; Baeckman J; Strom NI; Hagen K; Lindblad-Toh K; Karlsson EK; Pedersen NL; Wallert J; Bulik CM; Fundin B; Landen M; Kvale G; Hansen B; Haavik J; Mattheisen M; Rueck C; Mataix-Cols D; Crowley JJ
  • Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2023;31:100604
    Flygare O; Andersson E; Glimsdal G; Mataix-Cols D; Pascal D; Rueck C; Enander J
  • Article: JAMA NETWORK OPEN. 2022;5(3):e221967
    Lundstrom L; Flygare O; Andersson E; Enander J; Bottai M; Ivanov VZ; Boberg J; Pascal D; Mataix-Cols D; Ruck C
  • Article: IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY. 2019;41(1):117-122
    Lonndahl L; Rasul A; Lonne-Rahm S-B; Holst M; Johansson B; El-Nour H; Djurfeldt DR; Nordlind K
  • Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27(5):462-469
    Plaven-Sigray P; Hedman E; Victorsson P; Matheson GJ; Forsberg A; Djurfeldt DR; Ruck C; Halldin C; Lindefors N; Cervenka S
  • Article: ACTA DERMATO-VENEREOLOGICA. 2016;96(6):732-736
    Rasul A; El-Nour H; Lonne-Rahm S-B; Fransson O; Johansson C; Johanson B; Zubeidi M; Seeberg E; Radu Djurfeldt D; Azmitia EC; Nordlind K
  • Article: BEHAVIOR THERAPY. 2015;46(4):423-431
    Linde J; Ruck C; Bjureberg J; Ivanov VZ; Djurfeldt DR; Ramnero J
  • Article: JAMA PSYCHIATRY. 2015;72(7):659-667
    Andersson E; Hedman E; Enander J; Djurfeldt DR; Ljotsson B; Cervenka S; Isung J; Svanborg C; Mataix-Cols D; Kaldo V; Andersson G; Lindefors N; Ruck C
  • Article: TRANSLATIONAL PSYCHIATRY. 2012;2(5):e120
    Cervenka S; Hedman E; Ikoma Y; Djurfeldt DR; Ruck C; Halldin C; Lindefors N
  • Article: BRAIN RESEARCH. 2006;1104(1):175-182
    Radu D; Tomkinson B; Zachrisson O; Weber G; de Belleroche J; Hirsch S; Lindefors N
  • Article: MOLECULAR HUMAN REPRODUCTION. 2004;10(3):159-166
    Bruse C; Radu D; Bergqvist A
  • Article: PSYCHOPHARMACOLOGY. 2002;161(4):396-403
    Radu D; 脜hlin A; Svanborg P; Lindefors N
  • Article: BRAIN RESEARCH. 2001;908(2):197-203
    Radu D; Brodin E; Weber G; Lindefors N
  • Journal article: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2001;44(S1):s182-s184
    Halldin C; Hall H; Amir A; Radu D; Perrone R; Berardi F; Colabufo N; Leopoldo M
  • Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1999;11(5):1809-1817
    Dupuis DS; Pauwels PJ; Radu D; Hall H

Alla 枚vriga publikationer

  • Poster: HTTPS://ESSFNCONGRESS.ORG/PROGRAMME/. 2023
    OP047 Genomics of severe and treatment-resistant obsessive-compulsive disorder treated with deep brain stimulation: a preliminary investigation.
    Chen LL; Fytagoridis A; Pascal D
  • Preprint: MEDRXIV. 2021
    Flygare O; Andersson E; Glimsdal G; Mataix-Cols D; Djurfeldt D; R眉ck C; Enander J
  • Preprint: MEDRXIV. 2021
    Chen LL; Flygare O; Wallert J; Enander J; Ivanov V; R眉ck C; Djurfeldt D
  • Preprint: BIORXIV. 2017
    Noh HJ; Tang R; Flannick J; O鈥橠ushlaine C; Swofford R; Howrigan D; Genereux DP; Johnson J; van Grootheest G; Gr眉nblatt E; Andersson E; Djurfeldt DR; Patel PD; Koltookian M; Hultman C; Pato MT; Pato CN; Rasmussen SA; Jenike MA; Hanna GL; Stewart SE; Knowles JA; Ruhrmann S; Grabe H-J; Wagner M; R眉ck C; Mathews CA; Walitza S; Cath DC; Feng G; Karlsson EK; Lindblad-Toh K
  • Book chapter: SKIN AND PSYCHE. 2016;p. 88-99
  • Review: LAKARTIDNINGEN. 2016;113:DXMM
    Chen LL; Schechtmann G; Ring P; Djurfeldt D
  • Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:677-678
    Sigray PP; Hedman E; Ikonen P; Matheson G; Forsberg A; Djurfeldt D; Ruck C; Halldin C; Lindefors N; Cervenka S
  • Conference publication: SCHIZOPHRENIA RESEARCH. 2006;81:212
    Radu D; Tomkinson B; Zachrisson O; Weber G; De Belleroche J; Hirsch S; Lindefors N
  • Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 2003;57(2):105
    Radu D; 脜hlin A; Svanborg P; Lindefors N
  • Conference publication: EUROPEAN PSYCHIATRY. 2002;17:51S
    Radu D; 脜hlin A; Svanborg R; Lindefors N
  • Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 2001;55(2):101-102
    Radu D; Brodin E; Weber G; Lindefors N
  • Conference publication: EUROPEAN PSYCHIATRY. 2000;15:282S
    Radu D; Sedvall G
  • Meeting abstract: SCHIZOPHRENIA RESEARCH. 2000;41(1):254-255
    Radu D; Zachrisson O; de Belleroche J; Wendt KR; Hirsh S; Lindefors N
  • Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 1999;53(2):106
    Radu D; Brodin E; Lindefors N

Forskningsbidrag

  • Swedish Research Council
    1 January 2023 - 31 December 2024
  • Europeisk studie av livskvalitet f枚r patienter med refrakt盲rt tv氓ngssyndrom vid behandling med djup hj盲rnstimulering i nucleus subtalamicus (STN) j盲mf枚rt med b盲sta medicinska behandling (EQoLOC )
    Region Stockholm
    1 January 2021 - 1 January 2023
  • MIO: Microbioma in OCD
    FRF-Stiftelsen Fonden f枚r Rehabilitering och medicinsk forskning Insamlingsstiftelse
    1 January 2021 - 1 January 2023
  • Internet-based vs face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive disorder 鈥 a randomized controlled non-inferiority trial.
    ALF Region Stockholm
    1 January 2018 - 1 January 2020
  • Utveckling, klinisk pr枚vning och implementering av KBT-behandling med internetst枚d f枚r samlarsyndrom
    Region Stockholm
    1 January 2017 - 1 January 2018
  • Deep Brain Stimulation vid tv氓ngssyndrom, utv盲rdering av ny behandlingsmetod vid sv氓r och behandlingsresistent sjukdom i ett svenskt material
    Region Stockholm
    1 January 2014 - 1 January 2015
  • PET-studier av dopamin- och serotoninsystemen i hj盲rnan: biokemiska och beteendem盲ssiga fenotyper i relation till genetisk variation hos friska f枚rs枚kspersoner och patienter med social fobi.
    Region Stockholm
    1 January 2013 - 1 January 2014
  • Djup hj盲rnstimulering (deep brain stimulation, DBS) vid behandlingsresistent tv氓ngssyndrom: effekt av bi- respektive unilateral stimulering p氓 hj盲rnans dopaminsystem - korrelationer till symptomreduktion och livskvalitetsm氓tt
    厂枚诲别谤蝉迟谤枚尘-碍枚苍颈驳蝉办补
    1 January 2013 - 1 January 2016
  • Kognitiv beteendeterapi som Internetbehandling j盲mf枚rt med gruppbehandling vid paniksyndrom och social fobi samt behandlingssvarets association med biologisk variation
    Region Stockholm
    1 January 2007 - 1 January 2009

础苍蝉迟盲濒濒苍颈苍驳补谤

  • 脰verl盲kare, specialist i psykiatri, Psykiatri Sydv盲st, OCD-Programmet, Stockholm Health Care Services, 2014-
  • Anknuten till Forskning, Klinisk neurovetenskap, 探花精选, 2023-2026
  • Anknuten forskare/post doc, Neurovetenskap, psykiatri, Klinisk neurovetenskap, 探花精选, 2013-2023
  • 脰verl盲kare, specialist i psykiatri, Psykiatri Nordv盲st, Stockholm Health Care Services, 2010-2014
  • Anknuten forskare/post doc i Nils Lindefors forskagrupp, Klinisk neurovetenskap, Klinisk neurovetenskap, 探花精选, 2005-2012
  • Specialisttj盲nstg枚ring i psykiatri, Psykiatri Nordv盲st, Stockholm Health Care Services, 2005-2010
  • Allm盲ntj盲nstg枚ring f枚r l盲kare AT, Capio S:t G枚rans Sjukhus, 2002-2004

Examina och utbildning

  • Docent, Psykiatri, 探花精选, 2025
  • Teaching and Learning in Higher Education for Health Care Professionals 7, 5 credits, 探花精选, 2023
  • Docentprogrammet, Stockholm Health Care Services, 2023
  • Psychological Models of Psilocybin Drug Administration, 1, 5 credits, 探花精选, 2023
  • Psychedelic Science 鈥 Past, Present, Future, 1, 5 credits, 探花精选, 2023
  • Clinical Trials and Good Clinical Practice - ICH GCP - upgrade, Karolinska Trial Alliance/Karolinska University Hospital, 2023
  • Danska, baskurs 2, 7.5 po盲ng, Spr氓kkurs, danska, Stockholm University, 2020
  • Danska, baskurs 1, 15 po盲ng, Spr氓kkurs, danska, Stockholm University, 2019
  • Psychopharmacology, CPD-course corresponding 3 CME credits, Psykiatri Sydv盲st, Stockholm Health Care Services, 2016
  • Psychosis, spice, and all things nice, 3 hours CPD-course corresponding 3 CME credits with Robin Murray, IOP, Kings Kollege, London, Psykiatri Sydv盲st, Stockholm Health Care Services, 2016
  • Web course for research supervisors, 探花精选, 2016
  • Training course in Deep Brain Stimulation for Obsessive Compulsive Disorder, European Continuing Medical Training ECMT-course, granting 6 European CME credits with UEMS/EACCME, Course Directors Bart Nuttin and Loes Gabr茂els, , Medtronic training program, 2012
  • Course in Clinical trials and Good Clinical Practice (GCP), KTA-Prim and CeFAM, 探花精选, 2011
  • An introduction to ACT (Acceptance and Commitment Therapy), IPULS-course corresponding 3 CME credits, Swedish Psychiatry Association, , 2011
  • The neuroanatomy of emotion, IPULS-course corresponding 3 CME credits, Swedish Psychiatry Association, 2011
  • Training course in Deep Brain Stimulation & Obsessive Compulsive Disorder, European Continuing Medical Training ECMT-course, granting 12 European CME credits with UEMS/EACCME, Course Directors Damiaan Denys and Rick Schuurman, , Medtronic training program, 2011
  • Mindfulness-based cognitive therapy for prevention of relapse/recurrence in depression with Mark Williams, University of Oxford, Dpt of Psychiatry, UK, , KBT i Utveckling, Stockholm, Sweden, 2011
  • Evidence based medicine, IPULS-course, Karolinska University Hospital, 2010
  • Seminar on medicines and environment, Environment department, Stockholm County Council, , 2010
  • Kognitiv neurovetenskap med inriktning mot psykiatri, 10 po盲ng, Clinical neuroscience, 探花精选, 2010
  • Practical Leadership, IPULS-course, NIKE Organisationspsykologi, Sigtuna, Sweden, 2009
  • To supervise the resident doctor 鈥 the ABC of supervisors, Psykiatri Nordv盲st and Swedish Psychiatry Association, Stockholm Health Care Services, 2009
  • BPBBPDADHD 鈥 clinical assessment in the complex field of affect regulation, IPULS-course granting 3 CME credits, , Swedish Psychiatry Association, Stockholm, Sweden, 2009
  • Electroconvulsive Therapy 鈥 state of the art, IPULS-course granting 3 CME credits, Swedish Psychiatry Association, Stockholm, Sweden, 2009
  • Karolinska OCD Master Class with Naomi Fineberg, visiting professor from University of Herdfordshire, UK, Center for Psychiatry Research, 探花精选, 2009
  • Grundl盲ggande psykoterapiutbildnign med inrikting KBT (Steg-1 utbildning), 45 h枚gskolepo盲ng, Psykologpartners W&W AB, Stockholm, Sweden, 2008
  • Workshop on 鈥淚ntegrative Behavior Couple Therapy (IBCT)鈥 with Andrew Christensen, dpt of Psychology, University of California, LA, course held in Stockholm, Sweden, 2008
  • Karolinska Anxiety seminars 2008: BDD, organizer Sergej Andr茅ewitch, Psykiatri Nordv盲st, Stockholm Health Care Services, 2008
  • Manualized CBT-treatment of gambling addiction, Beroendecentrum Stockholm, 2007
  • Unbound psychopharmacology, Danderyds Hospital, Psychiatry, Section for research and education FoUU, Stockholm Health Care Services, , 2006
  • MEDICINE DOKTORSEXAMEN, Institutionen f枚r klinisk neurovetenskap, 探花精选, 2005
  • ADHD in children and adults, IPULS-course granting 3 CME credits, Swedish Psychiatry Association, 2003
  • 脜ngestsjukdomar - fr氓n amygdala till v氓rdcentral, Psykiatri Karolinska, 2003
  • Neuropsychiatry: Assessment and treatment of ADHD, Autism and Aspergers Syndrom in adults, IPULS-course, Psykiatri Karolinska, 2003
  • Social insurance medicine 鈥 general insurance, F枚rs盲kringskassan, 2003
  • Motivational Interviewing, IPULS-course, 探花精选, 2003
  • Psychopharmacology, 4, 5 credits, course for PhD students, 探花精选, 1999
  • Research school for clinically active researchers, total of 6 weeks theoretical education and 10 weeks of personalized laboratory practice under supervision, course for clinically active PhD students, 探花精选, 1998
  • mRNA in situ hybridization, 1, 5 credits, course for PhD students, 探花精选, 1998
  • Basic course in 探花精选 statistics, 1, 5 credits, course for PhD students, 探花精选, 1998
  • Hur man skriver en vetenskaplig rapport, 探花精选, 1998
  • Introduction to analysis of variance ANOVA, 1, 5 credits, course for PhD students, 探花精选, 1998
  • Functional anatomy of the human brain, 3 credits, 探花精选, 1998
  • Vetenskapsteori, 探花精选, 1998
  • Medicinsk Informationsteknologi, 探花精选, 1998
  • MOLEKYL脛RBIOLOGIKURS I FORSKARSKOLANS REGI, 探花精选, 1997
  • Basal molecular biology for clinical researchers, 1, 5 credits, course for PhD students, 探花精选, 1997
  • Modern receptor pharmacology, 1, 5 credits, course for PhD students, 探花精选, 1997
  • L盲karexamen, 探花精选, 1997

Uppdrag

  • Programdirektor, Studierektor f枚r specialisterna i psykiatri vid Psykiatri Sydv盲st, Psykiatri Sydv盲st, Stockholm Health Care Services, 2022-
  • Creating and implementing clinical flow charts and control codes for assessment, treatment and follow up for OCD- and related disorders, Process owner for the OCD-process, Psykiatri Sydv盲st, Stockholm Health Care Services, , 2020-
  • A supervised clinical scientific and quality project focusing in understanding and improving clinical practice, done during residency for 15 weeks full time work., Handledare vetenskapligt arbete och kvalitetsarbete- f枚r ST-l盲kare Katarina Nilsson "Tv氓ngssyndrom och brist p氓 vitaminerna B12 och D i ett svenskt patientmaterial 鈥 ett kliniskt kvalitetsprojekt med implikationer f枚r klinikens provtagningsrutiner", Psykiatri Sydv盲st, Stockholm Health Care Services, 2020-2022
  • C-uppsats, psykologi., Bihandledare f枚r Nina Keisu, C-uppsats, "Behandlingsutfall f枚r patienter med OCD i relation till medicinering och vitaminers p氓verkan 鈥 En retrospektiv longitudinell studie.", Mittuniversitetet, 2017-2017
  • Depression, 氓ngestsyndrom och tv氓ngssyndrom hos barn och vuxna - behandlingsrekommendation: Information fr氓n L盲kemedelsverket 2016
  • 27(6):26鈥59., Depression, 氓ngestsyndrom och tv氓ngssyndrom hos barn och vuxna - behandlingsrekommendation: Information fr氓n L盲kemedelsverket 2016
  • 27(6):26鈥59., Medical Products Agency, , 2016-2016
  • Co-supervisor in 30-points examination essay in medicine, ethically approved project Dnr 2015/1236-31, Bihandledare f枚r Edvard Nilsson, med kand T 8, Examensarbete i medicin (30 po盲ng), Clinical Neuroscience, 探花精选, 2015-2016
  • Creating and implementing clinical flow charts and control codes for assessment, treatment and follow up for OCD- and related disorders, Process盲gare OCD-processen, Psykiatri Sydv盲st, Stockholm Health Care Services, , 2015-2018
  • Medical responsibility for health care given at the OCD-Program, OCD-Programmet, PSV, Psykiatri Sydv盲st, OCD-Programmet, Stockholm Health Care Services, 2015-2018
  • Member of priority group for guidelines in depression and anxiety disorders, working according to the 鈥渘ational model for open prioritizing in health care鈥, National Board of Health and Welfare, 2015-2016
  • Studierektor, Assistent, Psykiatri Sydv盲st, Stockholm Health Care Services/探花精选, 2015-2017
  • A supervised clinical scientific and quality project focusing in understanding and improving clinical practice, done during residency for 15 weeks full time work., Handledare vetenskapligt arbete och kvalitetsarbete- f枚r ST-l盲kare Sasa Markovic "Utv盲rdering av behandling med Responsprevention (ERP) f枚r patienter med Tv氓ngssyndrom", Psykiatri Nordv盲st, Stockholm Health Care Services, 2013-2014
  • A supervised clinical scientific and quality project focusing in understanding and improving clinical practice, done during residency for 15 weeks full time work., Handledare vetenskapligt arbete och kvalitetsarbete- f枚r ST-l盲kare Sigrid Storetvedt P氓 vilket s盲tt p氓verkar samtidig farmakologisk behandling utfallet av KBT vid OCD-spektrumst枚rning?, Psykiatri Nordv盲st, Stockholm Health Care Services, 2012-2012
  • Co-supervisor in 30-points examination essay in medicine, ethically approved project Dnr 2015/1236-31, Bihandledare examensuppsats f枚r Sara Gunnarsson & Michael Hoff, "Karakteristik av och behandlingsutfall f枚r patienter med tv氓ngssyndrom (OCD) vid en specialiserad psykiatrisk klinik: Vad inverkar p氓 effekten av behandling med responsprevention (ERP)?", Institutionen f枚r psykologi, Uppsala University, 2011-2011
  • Creating flow charts for clinical assessment, treatment and follow up for anxiety and OCD-RT diagnoses., Coordinator for anxiety- and OCD-processes in specialized psychiatric healthcare, Psykiatri Nordv盲st, Stockholm Health Care Services, 2010-2014
  • Hududhandledare f枚r ST-l盲kare Kim Gosai and Daniela Enache, Psykiatri Nordv盲st and Psykiatri Sydv盲st, Stockholm Health Care Services, 2010-2020
  • Prefekt, Enhetschef 脜ngestenheten Psykiatri Nordv盲st, SLSO, Anxiety department, Psykiatri Nordv盲st, Stockholm Health Care Services, 2010-2014
  • Sektionsansvarig, Kursutvecklare, kursgivare och examinator f枚r METIS-kurser f枚r svenska ST-l盲kare i psykiatri, Centre for Psychiatry Research, Stockholm Health Care Services/探花精选, 2009-

Handledning

  • Long Long Chen, Obsessive-compulsive disorder : novel insights on executive functions, gut microbiome, and genetics,

Uppdrag i kommitt茅

  • Medlem, Region Stockholms L盲kemedelskomitt茅 s Expertr氓d, rug Therapeutic Committee and the Health and Medical Care Administration, Stockholm Health Care Services, , 2013-2018
  • Medlem, Svenska PSykiatriska F枚reningen, Swedish Psychiatric Association, 2012-2014
  • Medlem, Svenska Psykiatriska F枚reningen, Swedish Psychiatric Association, 2010-2012

Konferenser och events

  • Muntliga presentationer av egna accepterade abstract, The European Society for Stereotactic and Functional Neurosurgery Congress 2023, , OP047 Genomics of severe and treatment-resistant obsessive-compulsive disorder treated with deep brain stimulation: a preliminary investigation. ABSTRACT: Individuals with severe and treatment-resistant obsessive-compulsive disorder (trOCD) represent a small but severely disabled group of patients. Since trOCD cases eligible for deep brain stimulation (DBS) probably comprise the most severe end of the OCD spectrum, we hypothesize that they may be more likely to have substantial detectable genetic contributions. Therefore, while the worldwide population of DBS-treated cases may be small (~300), screening these individuals with modern genomic methods may accelerate gene discovery in OCD. As such, we have begun to collect DNA from trOCD cases who qualify for DBS, and here we report results from whole exome sequencing and microarray genotyping of our first five cases. All participants had previously received DBS in the bed nucleus of stria terminalis (BNST), with two patients responding to the surgery and one showing a partial response. Our analyses focused on gene-disruptive rare variants (GDRVs
  • rare, predicted-deleterious single-nucleotide variants or copy number variants overlapping protein-coding genes). Three of the five cases carried a GDRV, including a missense variant in the ion transporter domain of KCNB1, a deletion at 15q11.2, and a duplication at 15q26.1. The KCNB1 variant (hg19 chr20-47991077-C-T, NM_004975.3:c.1020G>A, p.Met340Ile) causes substitution of methionine for isoleucine in the trans-membrane region of neuronal potassium voltage-gated ion channel KV2.1. This KCNB1 substitution (Met340Ile) is located in a highly constrained region of the protein where other rare missense variants have previously been associated with neurodevelopmental disorders. The patient carrying the Met340Ile variant responded to DBS, which suggests that genetic factors could potentially be predictors of treatment response in DBS for OCD. In sum, we have established a protocol for recruiting and genomically characterizing trOCD cases. Preliminary results suggest that this will be an informative strategy for finding risk genes in OCD., 2023
  • Deltagare, The 6th Maudsley Forum, Yearly psychiatry course held for international residents in Psychiatry at the Institute of Psychiatry, Kings Kollege, London, 2006
  • Poster-presentationer av egna accepterade abstract, SCNP 42nd Annual and 1st Mediterranean Meeting. 0, 6 credits., Delayed stress-induced increase in tissue level of cholecystokinin in rat prefrontal cortex: Modulation by microdialysis probe implantation鈥, Radu, D
  • Brodin, E
  • (...)
  • Lindefors, N, 2001, 2001
  • Poster-presentationer av egna accepterade abstract, The society for neuroscience 2001 Annual Meeting. Poster presentation. San Diego, California, USA. November, 10-15, 2001, 鈥淗uman CCKA receptor mRNA distribution in human and primate brain - alterations following schizophrenia 鈥漅adu, D
  • Zachrisson, O
  • de Belleroche, J
  • Hirsh, S
  • Lindefors, 2001, 2001
  • Poster-presentationer av egna accepterade abstract, 0th Biennial Winter Workshop on SCHIZOPHRENIA. Abstract. Davos, Schweiz. February, 5-11, 2000 1.5 credits, 2000
  • Poster-presentationer av egna accepterade abstract, Conference on Neuronal cholecystokinin. Poster. Queens College, Oxford, England. August, 13-18, 2000, 0, 9 credits, 2000
  • Poster-presentationer av egna accepterade abstract, 39th Annual Meeting of the Scandinavian Society for. Psychopharmacology, Copenhagen, Denmark, Cholecystokinin involvement in environmental stress and psychosis鈥, Radu, D
  • Brodin, E and Lindefors, N, 1999, 1998

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